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Search Results - McNaughton-Smith, G
Search Results - McNaughton-Smith, G
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N-(6-Chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): A Novel, Selective KCNQ2/Q3 Potassium Channel Activator
by
Wickenden, A D
,
Krajewski, J L
,
London, B
,
Wagoner, P K
,
Wilson, W A
,
Clark, S
,
Roeloffs, R
,
McNaughton-Smith, G
,
Rigdon, G C
Published in
Molecular pharmacology
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In Vivo Profile of ICA-27243 [N-(6-Chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a Potent and Selective KCNQ2/Q3 (Kv7.2/Kv7.3) Activator in Rodent Anticonvulsant Models
by
Roeloffs, Rosemarie
,
Wickenden, Alan D
,
Crean, Christopher
,
Werness, Stephen
,
McNaughton-Smith, Grant
,
Stables, James
,
McNamara, James O
,
Ghodadra, Neil
,
Rigdon, Greg C
Published in
The Journal of pharmacology and experimental therapeutics
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ICA-17043, a novel Gardos channel blocker, prevents sickled red blood cell dehydration in vitro and in vivo in SAD mice
by
Stocker, Jonathan W.
,
De Franceschi, Lucia
,
McNaughton-Smith, Grant A.
,
Corrocher, Roberto
,
Beuzard, Yves
,
Brugnara, Carlo
Published in
Blood
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Exploration of beta-turn scaffolding motifs as components of sialyl Le(X) mimetics and their relevance to P-selectin
by
Hanessian, S
,
Huynh, H K
,
Reddy, G V
,
McNaughton-Smith, G
,
Ernst, B
,
Kolb, H C
,
Magnani, J
,
Sweeley, C
Published in
Bioorganic & medicinal chemistry letters
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Exploration of β-turn scaffolding motifs as components of sialyl Lex mimetics and their relevance to P-selectin
by
HANESSIAN, S
,
HUYNH, H. K
,
REDDY, G. V
,
MCNAUGHTON-SMITH, G
,
ERNST, B
,
KOLB, H. C
,
MAGNANI, J
,
SWEELEY, C
Published in
Bioorganic & medicinal chemistry letters
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The stereoselective synthesis of unsaturated nine-membered lactones using the Malherbe-Bellus variant of the Claisen rearrangement
by
KLING, M. R
,
MCNAUGHTON-SMITH, G. A
,
TAYLOR, R. J. K
Published in
Journal of the Chemical Society. Chemical communications
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Design and synthesis of conformationally constrained amino acids as versatile scaffolds and peptide mimetics
by
Hanessian, Stephen
,
McNaughton-Smith, Grant
,
Lombart, Henry-Georges
,
Lubell, William D.
Published in
Tetrahedron
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Process Development and Optimization for Production of a Potassium Ion Channel Blocker, ICA-17043
by
Mobele, Bingidimi I
,
Venkatraman, Sripathy
,
McNaughton-Smith, Grant
,
Gibb, Cameron
,
Ulysse, Luckner G
,
Lindmark, Carl A
,
Shaw, Stephen
,
Marron, Brian
,
Spear, Kerry
,
Suto, Mark J
Published in
Organic process research & development
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Synthesis of (4 S)-hydroxymethyl-(2 R)-(2-propyl)-butyrolactone: A quest for a practical route to an important hydroxyethylene isostere chiron
by
Hanessian, Stephen
,
Abad-Grillo, Teresa
,
McNaughton-Smith, Grant
Published in
Tetrahedron
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N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of Epilepsy
by
Amato, George
,
Roeloffs, Rosemarie
,
Rigdon, Greg C
,
Antonio, Brett
,
Mersch, Theresa
,
McNaughton-Smith, Grant
,
Wickenden, Alan D
,
Fritch, Paul
,
Suto, Mark J
Published in
ACS medicinal chemistry letters
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Synthesis and in vitro antiprotozoal evaluation of substituted phenalenone analogues
by
Rosquete, Laura I.
,
Cabrera-Serra, M. Gabriela
,
Piñero, José E.
,
Martín-Rodríguez, Patricia
,
Fernández-Pérez, Leandro
,
Luis, Javier G.
,
McNaughton-Smith, Grant
,
Abad-Grillo, Teresa
Published in
Bioorganic & medicinal chemistry
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A versatile synthesis of a β-turn peptidomimetic scaffold: An approach towards a designed model antagonist of the tachykinin NK-2 receptor
by
Hanessian, Stephen
,
McNaughton-Smith, Grant
Published in
Bioorganic & medicinal chemistry letters
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The preparation of 9-substituted Δ 5-octenolides: Synthesis of 8-deoxy-pseudo-ascidiatrienolide C
by
McNaughton-Smith, Grant A.
,
Taylor, Richard J.K.
Published in
Tetrahedron
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