Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites by Field, Jessica J, Pera, Benet, Gallego, Juan Estévez, Calvo, Enrique, Rodríguez-Salarichs, Javier, Sáez-Calvo, Gonzalo, Zuwerra, Didier, Jordi, Michel, Andreu, José M, Prota, Andrea E, Ménchon, Grégory, Miller, John H, Altmann, Karl-Heinz, Díaz, J. Fernando

Get full text

Quinazolinone-Based Anticancer Agents: Synthesis, Antiproliferative SAR, Antitubulin Activity, and Tubulin Co-crystal Structure by Dohle, Wolfgang, Jourdan, Fabrice L, Menchon, Grégory, Prota, Andrea E, Foster, Paul A, Mannion, Pascoe, Hamel, Ernest, Thomas, Mark P, Kasprzyk, Philip G, Ferrandis, Eric, Steinmetz, Michel O, Leese, Mathew P, Potter, Barry V. L

Get full text

Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent by Jost, Marco, Chen, Yuwen, Gilbert, Luke A., Horlbeck, Max A., Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y., Stern, Jacob J., Prota, Andrea E., Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O., Tanenbaum, Marvin E., Weissman, Jonathan S.

Get full text

A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin by Menchon, Grégory, Prota, Andrea E., Lucena-Agell, Daniel, Bucher, Pascal, Jansen, Rolf, Irschik, Herbert, Müller, Rolf, Paterson, Ian, Díaz, J. Fernando, Altmann, Karl-Heinz, Steinmetz, Michel O.

Get full text

Pharmaceutical-Grade Rigosertib Is a Microtubule-Destabilizing Agent by Jost, Marco, Chen, Yuwen, Gilbert, Luke A., Horlbeck, Max A., Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y., Stern, Jacob J., Prota, Andrea E., Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O., Tanenbaum, Marvin E., Weissman, Jonathan S.

Get full text

Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents by Brindisi, Margherita, Ulivieri, Cristina, Alfano, Gloria, Gemma, Sandra, de Asís Balaguer, Francisco, Khan, Tuhina, Grillo, Alessandro, Chemi, Giulia, Menchon, Grégory, Prota, Andrea E., Olieric, Natacha, Lucena-Agell, Daniel, Barasoain, Isabel, Diaz, J. Fernando, Nebbioso, Angela, Conte, Mariarosaria, Lopresti, Ludovica, Magnano, Stefania, Amet, Rebecca, Kinsella, Paula, Zisterer, Daniela M., Ibrahim, Ola, O'Sullivan, Jeff, Morbidelli, Lucia, Spaccapelo, Roberta, Baldari, Cosima, Butini, Stefania, Novellino, Ettore, Campiani, Giuseppe, Altucci, Lucia, Steinmetz, Michel O., Brogi, Simone

Get full text

Structure-Based Virtual Ligand Screening on the XRCC4/DNA Ligase IV Interface by Menchon, Grégory, Bombarde, Oriane, Trivedi, Mansi, Négrel, Aurélie, Inard, Cyril, Giudetti, Brigitte, Baltas, Michel, Milon, Alain, Modesti, Mauro, Czaplicki, Georges, Calsou, Patrick

Get full text

Tetrahydroisoquinoline Sulfamates as Potent Microtubule Disruptors: Synthesis, Antiproliferative and Antitubulin Activity of Dichlorobenzyl-Based Derivatives, and a Tubulin Cocryst... by Dohle, Wolfgang, Prota, Andrea E, Menchon, Grégory, Hamel, Ernest, Steinmetz, Michel O, Potter, Barry V. L

Get full text

Anisomycin Injection in Area CA3 of the Hippocampus Impairs Both Short-Term and Long-Term Memories of Contextual Fear by Remaud, Jessica, Ceccom, Johnatan, Carponcy, Julien, Dugué, Laura, Menchon, Gregory, Pech, Stéphane, Halley, Helene, Francés, Bernard, Dahan, Lionel

Get full text

Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ pathology are detected... by Suárez‐Calvet, Marc, Karikari, Thomas K, Ashton, Nicholas J, Lantero Rodríguez, Juan, Milà‐Alomà, Marta, Gispert, Juan Domingo, Salvadó, Gemma, Minguillon, Carolina, Fauria, Karine, Shekari, Mahnaz, Grau‐Rivera, Oriol, Arenaza‐Urquijo, Eider M, Sala‐Vila, Aleix, Sánchez‐Benavides, Gonzalo, González‐de‐Echávarri, José Maria, Kollmorgen, Gwendlyn, Stoops, Erik, Vanmechelen, Eugeen, Zetterberg, Henrik, Blennow, Kaj, Molinuevo, José Luis, Beteta, Annabella, Cacciaglia, Raffaele, Cañas, Alba, Deulofeu, Carme, Cumplido, Irene, Dominguez, Ruth, Emilio, Maria, Falcon, Carles, Fuentes, Sherezade, Hernandez, Laura, Huesa, Gema, Huguet, Jordi, Marne, Paula, Menchón, Tania, Operto, Grégory, Polo, Albina, Pradas, Sandra, Soteras, Anna, Vilanova, Marc, Vilor‐Tejedor, Natalia

Get full text

Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder: Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group by Boedhoe, Premika S.W, Abe, Yoshinari, Alonso, Pino, Ameis, Stephanie H, Anticevic, Alan, Arnold, Paul D, Beucke, Jan C, Bollettini, Irene, Bose, Anushree, Brem, Silvia, Calvo, Anna, Calvo, Rosa, Denys, Damiaan, Feusner, Jamie D, Fitzgerald, Kate D, Fouche, Jean-Paul, Fridgeirsson, Egill A, Hibar, Derrek P, Hoexter, Marcelo Q, Hu, Hao, Jahanshad, Neda, James, Anthony, Kathmann, Norbert, Kaufmann, Christian, Lazaro, Luisa, Lochner, Christine, Marsh, Rachel, Martínez-Zalacaín, Ignacio, Mataix-Cols, David, Menchón, José M, Minuzzi, Luciano, Nakamae, Takashi, Nakao, Tomohiro, Nurmi, Erika, O’Neill, Joseph, Piacentini, John, Piras, Fabrizio, Piras, Federica, Reess, Tim J, Sato, Joao R, Soriano-Mas, Carles, Stevens, Michael C, Szeszko, Philip R, van Wingen, Guido A, Venkatasubramanian, Ganesan, Walitza, Susanne, Wang, Zhen, Yun, Je-Yeon, Stein, Dan J, Boedhoe, Premika S.W, Abe, Yoshinari, Anticevic, Alan, Batistuzzo, Marcelo C, Benedetti, Francesco, Bollettini, Irene, Bose, Anushree, Calvo, Anna, Calvo, Rosa, Cheng, Yuqi, Ciullo, Valentina, Denys, Damiaan, Drechsler, Renate, Fang, Yu, Feusner, Jamie D, Fouche, Jean-Paul, Hanna, Gregory L, Hauser, Tobias U, Huyser, Chaim, Iorio, Mariangela, James, Anthony, Khadka, Sabin, Kwon, Jun Soo, Liu, Yanni, Marsh, Rachel, Martínez-Zalacaín, Ignacio, Mataix-Cols, David, McCracken, James T, Miguel, Euripedes C, Morer, Astrid, Narumoto, Jin, Nishida, Seiji, Nurmi, Erika, Pariente, Jose C, Pittenger, Christopher, Piras, Fabrizio, Piras, Federica, Poletti, Sara, Reddy, Y.C. Janardhan, Tang, Jinsong, Vecchio, Daniela, Veltman, Dick J, Venkatasubramanian, Ganesan, Wang, Zhen, Watanabe, Anri, Xu, Jian, Xu, Xiufeng, Yun, Je-Yeon, Zhao, Qing, Thompson, Paul M, van den Heuvel, Odile A

Get full text

Distinct Subcortical Volume Alterations in Pediatric and Adult OCD: A Worldwide Meta- and Mega-Analysis by Boedhoe, Premika S.W, Schmaal, Lianne, Abe, Yoshinari, Ameis, Stephanie H, Batistuzzo, Marcelo C, Benedetti, Francesco, Beucke, Jan C, Bose, Anushree, Brem, Silvia, Calvo, Anna, Cheng, Yuqi, Cho, Kang Ik K, Dallaspezia, Sara, Gruner, Patricia, Hanna, Gregory L, Hibar, Derrek P, Hoexter, Marcelo Q, Hu, Hao, Huyser, Chaim, Jahanshad, Neda, Kaufmann, Christian, Koch, Kathrin, Lazaro, Luisa, Liu, Yanni, Lochner, Christine, Marsh, Rachel, Mataix-Cols, David, Menchón, José M, Minuzzi, Luciano, Narayanaswamy, Janardhanan C, Piras, Fabrizio, Piras, Federica, Pittenger, Christopher, Reddy, Y.C. Janardhan, Sato, Joao R, Soreni, Noam, Szeszko, Philip R, Xu, Jian, Xu, Xiufeng, Yun, Je-Yeon, Zhao, Qing, Stein, Dan J, Ameis, Stephanie H, Bargalló, Nuria, Batistuzzo, Marcelo C, Benedetti, Francesco, Beucke, Jan C, Boedhoe, Premika S.W, Calvo, Anna, Calvo, Rosa, Cath, Danielle C, Cheng, Yuqi, Cho, Kang Ik K, de Vries, Froukje E, Fang, Yu, Fitzgerald, Kate D, Fouche, Jean-Paul, Giménez, Mònica, Hanna, Gregory L, Hu, Hao, Huyser, Chaim, Ikari, Keisuke, Jahanshad, Neda, Kathmann, Norbert, Kaufmann, Christian, Khadka, Sabin, Koch, Kathrin, Kwon, Jun Soo, Lazaro, Luisa, Liu, Yanni, Lochner, Christine, Marsh, Rachel, Martínez-Zalacaín, Ignacio, Mataix-Cols, David, Menchón, José M, Minuzzii, Luciano, Morer, Astrid, Nakamae, Takashi, Nakao, Tomohiro, Pittenger, Christopher, Reddy, Y.C. Janardhan, Sato, Joao R, Simpson, H. Blair, Soreni, Noam, Soriano-Mas, Carles, Spalletta, Gianfranco, Stein, Dan J, Stevens, Michael C, Szeszko, Philip R, Thompson, Paul M, Venkatasubramanian, Ganesan, van den Heuvel, Odile A, van der Werf, Ysbrand D, van Wingen, Guido A, Walitza, Susanne, Wang, Zhen, Xu, Jian, Xu, Xiufeng, Yun, Je-Yeon, Zhao, Qing

Get full text

Association between insomnia and cognitive performance, gray matter volume, and white matter microstructure in cognitively unimpaired adults by Grau-Rivera, Oriol, Operto, Grégory, Falcón, Carles, Sánchez-Benavides, Gonzalo, Cacciaglia, Raffaele, Brugulat-Serrat, Anna, Gramunt, Nina, Salvadó, Gemma, Suárez-Calvet, Marc, Minguillon, Carolina, Iranzo, Álex, Gispert, Juan Domingo, Molinuevo, José Luis

Get full text

Mapping Cortical and Subcortical Asymmetry in Obsessive-Compulsive Disorder: Findings From the ENIGMA Consortium by Kong, Xiang-Zhen, Boedhoe, Premika S.W., Ameis, Stephanie H., Assogna, Francesca, Batistuzzo, Marcelo C., Benedetti, Francesco, Bollettini, Irene, Brem, Silvia, Buitelaar, Jan, Dallaspezia, Sara, Denys, Damiaan, Ely, Benjamin A., Fitzgerald, Kate D., Fridgeirsson, Egill A., Glahn, David C., Hirano, Yoshiyuki, Huyser, Chaim, James, Anthony, Jaspers-Fayer, Fern, Kaufmann, Christian, Koch, Kathrin, Liu, Yanni, Lochner, Christine, Menchón, José M., Moreira, Pedro S., Nakagawa, Akiko, Narayanaswamy, Janardhanan C., Nurmi, Erika L., Pariente, Jose C., Piras, Federica, Pittenger, Christopher, Rus-Oswald, Oana Georgiana, Simpson, H. Blair, van Rooij, Daan, Venkatasubramanian, Ganesan, Wang, Zhen, Yun, Je-Yeon, Boedhoe, Premika S.W., Alonso, Pino, Anticevic, Alan, Arnold, Paul D., Assogna, Francesca, Batistuzzo, Marcelo C., Benedetti, Francesco, Beucke, Jan C., Brem, Silvia, Brennan, Brian P., Calvo, Rosa, Cheng, Yuqi, Dallaspezia, Sara, Denys, Damiaan, de Vries, Froukje E., de Wit, Stella J., Ely, Benjamin A., Esteves, Madalena, Falini, Andrea, Fitzgerald, Kate D., Fouche, Jean-Paul, Fridgeirsson, Egill A., Hall, Geoff, Hu, Hao, Huyser, Chaim, Jahanshad, Neda, Kuno, Masaru, Kvale, Gerd, Liu, Yanni, Magalhães, Ricardo, Marsh, Rachel, Masuda, Yasutaka, Mataix-Cols, David, Miguel, Euripedes C., Nakamae, Takashi, Nakao, Tomohiro, Narayanaswamy, Janardhanan C., Nurmi, Erika L., Pariente, Jose C., Piras, Fabrizio, Poletti, Sara, Rus-Oswald, Oana Georgiana, Sakai, Yuki, Shimizu, Eiji, Simpson, H. Blair, Stern, Emily R., Stevens, Michael C., Szeszko, Philip R., Takahashi, Jumpei, Tang, Jinsong, Thorsen, Anders Lillevik, van Wingen, Guido A., Veltman, Dick J., Venkatasubramanian, Ganesan, Walitza, Susanne, Xu, Jian, Xu, Xiufeng, Yoshida, Tokiko, Yun, Je-Yeon, Zarei, Mojtaba, Zhao, Qing, Stein, Dan J., Francks, Clyde

Get full text

Centiloid cut-off values for optimal agreement between PET and CSF core AD biomarkers by Salvadó, Gemma, Molinuevo, José Luis, Brugulat-Serrat, Anna, Falcon, Carles, Grau-Rivera, Oriol, Suárez-Calvet, Marc, Pavia, Javier, Niñerola-Baizán, Aida, Perissinotti, Andrés, Lomeña, Francisco, Minguillon, Carolina, Fauria, Karine, Zetterberg, Henrik, Blennow, Kaj, Gispert, Juan Domingo

Get full text

Age, sex and APOE-ε4 modify the balance between soluble and fibrillar β-amyloid in non-demented individuals: topographical patterns across two independent cohorts by Cacciaglia, Raffaele, Salvadó, Gemma, Molinuevo, José Luis, Shekari, Mahnaz, Falcon, Carles, Operto, Gregory, Suárez-Calvet, Marc, Milà-Alomà, Marta, Sala, Arianna, Rodriguez-Vieitez, Elena, Kollmorgen, Gwendlyn, Suridjan, Ivonne, Blennow, Kaj, Zetterberg, Henrik, Gispert, Juan Domingo

Get full text

Structural neuroimaging biomarkers for obsessive-compulsive disorder in the ENIGMA-OCD consortium: medication matters by Bruin, Willem B., Taylor, Luke, Thomas, Rajat M., Shock, Jonathan P., Zhutovsky, Paul, Abe, Yoshinari, Alonso, Pino, Ameis, Stephanie H., Anticevic, Alan, Arnold, Paul D., Assogna, Francesca, Benedetti, Francesco, Beucke, Jan C., Boedhoe, Premika S. W., Bollettini, Irene, Bose, Anushree, Brem, Silvia, Brennan, Brian P., Buitelaar, Jan K., Calvo, Rosa, Cheng, Yuqi, Cho, Kang Ik K., Dallaspezia, Sara, Denys, Damiaan, Ely, Benjamin A., Feusner, Jamie D., Fitzgerald, Kate D., Fouche, Jean-Paul, Fridgeirsson, Egill A., Gruner, Patricia, Gürsel, Deniz A., Hauser, Tobias U., Hirano, Yoshiyuki, Hoexter, Marcelo Q., Hu, Hao, Huyser, Chaim, Ivanov, Iliyan, James, Anthony, Jaspers-Fayer, Fern, Kathmann, Norbert, Kaufmann, Christian, Koch, Kathrin, Kuno, Masaru, Kvale, Gerd, Kwon, Jun Soo, Liu, Yanni, Lochner, Christine, Lázaro, Luisa, Marques, Paulo, Marsh, Rachel, Martínez-Zalacaín, Ignacio, Mataix-Cols, David, Menchón, José M., Minuzzi, Luciano, Moreira, Pedro S., Morer, Astrid, Morgado, Pedro, Nakagawa, Akiko, Nakamae, Takashi, Nakao, Tomohiro, Narayanaswamy, Janardhanan C., Nurmi, Erika L., O’Neill, Joseph, Pariente, Jose C., Perriello, Chris, Piacentini, John, Piras, Fabrizio, Piras, Federica, Reddy, Y. C. Janardhan, Rus-Oswald, Oana G., Sakai, Yuki, Sato, João R., Schmaal, Lianne, Shimizu, Eiji, Simpson, H. Blair, Soreni, Noam, Soriano-Mas, Carles, Spalletta, Gianfranco, Stern, Emily R., Stevens, Michael C., Stewart, S. Evelyn, Szeszko, Philip R., Tolin, David F., Venkatasubramanian, Ganesan, Wang, Zhen, Yun, Je-Yeon, van Rooij, Daan, Thompson, Paul M., van den Heuvel, Odile A., Stein, Dan J., van Wingen, Guido A.

Get full text

Patterns of white matter hyperintensities associated with cognition in middle-aged cognitively healthy individuals by Brugulat-Serrat, Anna, Salvadó, Gemma, Sudre, Carole H., Grau-Rivera, Oriol, Suárez-Calvet, Marc, Falcon, Carles, Sánchez-Benavides, Gonzalo, Gramunt, Nina, Fauria, Karine, Cardoso, M. Jorge, Barkhof, Frederik, Molinuevo, José Luis, Gispert, Juan Domingo

Get full text

An Empirical Comparison of Meta- and Mega-Analysis With Data From the ENIGMA Obsessive-Compulsive Disorder Working Group by Boedhoe, Premika S W, Heymans, Martijn W, Schmaal, Lianne, Abe, Yoshinari, Alonso, Pino, Ameis, Stephanie H, Anticevic, Alan, Arnold, Paul D, Batistuzzo, Marcelo C, Benedetti, Francesco, Beucke, Jan C, Bollettini, Irene, Bose, Anushree, Brem, Silvia, Calvo, Anna, Calvo, Rosa, Cheng, Yuqi, Cho, Kang Ik K, Ciullo, Valentina, Dallaspezia, Sara, Denys, Damiaan, Feusner, Jamie D, Fitzgerald, Kate D, Fouche, Jean-Paul, Fridgeirsson, Egill A, Gruner, Patricia, Hanna, Gregory L, Hibar, Derrek P, Hoexter, Marcelo Q, Hu, Hao, Huyser, Chaim, Jahanshad, Neda, James, Anthony, Kathmann, Norbert, Kaufmann, Christian, Koch, Kathrin, Kwon, Jun Soo, Lazaro, Luisa, Lochner, Christine, Marsh, Rachel, Martínez-Zalacaín, Ignacio, Mataix-Cols, David, Menchón, José M, Minuzzi, Luciano, Morer, Astrid, Nakamae, Takashi, Nakao, Tomohiro, Narayanaswamy, Janardhanan C, Nishida, Seiji, Nurmi, Erika L, O'Neill, Joseph, Piacentini, John, Piras, Fabrizio, Piras, Federica, Reddy, Y C Janardhan, Reess, Tim J, Sakai, Yuki, Sato, Joao R, Simpson, H Blair, Soreni, Noam, Soriano-Mas, Carles, Spalletta, Gianfranco, Stevens, Michael C, Szeszko, Philip R, Tolin, David F, van Wingen, Guido A, Venkatasubramanian, Ganesan, Walitza, Susanne, Wang, Zhen, Yun, Je-Yeon, Thompson, Paul M, Stein, Dan J, van den Heuvel, Odile A, Twisk, Jos W R

Get full text

Associations of medication with subcortical morphology across the lifespan in OCD: Results from the international ENIGMA Consortium by Ivanov, Iliyan, Boedhoe, Premika S.W., Abe, Yoshinari, Alonso, Pino, Ameis, Stephanie H., Arnold, Paul D., Balachander, Srinivas, Baker, Justin T., Banaj, Nerisa, Bargalló, Nuria, Batistuzzo, Marcelo C., Benedetti, Francesco, Beucke, Jan C., Bollettini, Irene, Brem, Silvia, Brennan, Brian P., Buitelaar, Jan, Calvo, Rosa, Cheng, Yuqi, Cho, Kang Ik K., Dallaspezia, Sara, Denys, Damiaan, Diniz, Juliana B., Ely, Benjamin A., Feusner, Jamie D., Ferreira, Sónia, Fitzgerald, Kate D., Fontaine, Martine, Gruner, Patricia, Hanna, Gregory L., Hirano, Yoshiyuki, Hoexter, Marcelo Q., Huyser, Chaim, Ikari, Keisuke, James, Anthony, Jaspers-Fayer, Fern, Jiang, Hongyan, Kathmann, Norbert, Kaufmann, Christian, Kim, Minah, Koch, Kathrin, Kwon, Jun Soo, Lázaro, Luisa, Liu, Yanni, Lochner, Christine, Marsh, Rachel, Martínez-Zalacaín, Ignacio, Mataix-Cols, David, Menchón, José M., Minuzzi, Luciano, Morer, Astrid, Morgado, Pedro, Nakagawa, Akiko, Nakamae, Takashi, Nakao, Tomohiro, Narayanaswamy, Janardhanan C., Nurmi, Erika L., Oh, Sanghoon, Perriello, Chris, Piacentini, John C., Picó-Pérez, Maria, Piras, Fabrizio, Piras, Federica, Reddy, Y.C. Janardhan, Manrique, Daniela Rodriguez, Sakai, Yuki, Shimizu, Eiji, Simpson, H. Blair, Soreni, Noam, Soriano-Mas, Carles, Spalletta, Gianfranco, Stern, Emily R., Stevens, Michael C., Stewart, S. Evelyn, Szeszko, Philip R., Tolin, David F., van Rooij, Daan, Veltman, Dick J., van der Werf, Ysbrand D., van Wingen, Guido A., Venkatasubramanian, Ganesan, Walitza, Susanne, Wang, Zhen, Watanabe, Anri, Wolters, Lidewij H., Xu, Xiufeng, Yun, Je-Yeon, Zarei, Mojtaba, Zhang, Fengrui, Zhao, Qing, Jahanshad, Neda, Thomopoulos, Sophia I., Thompson, Paul M., Stein, Dan J., van den Heuvel, Odile A., O'Neill, Joseph, Poletti, Sara, Fridgeirsson, Egill Axfjord, Ikuta, Toshikazu, de Wit, Stella J.

Get full text