Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity by Zhong, Wenqun, Lu, Youtao, Han, Xuexiang, Yang, Jingbo, Qin, Zhiyuan, Zhang, Wei, Yu, Ziyan, Wu, Bin, Liu, Shujing, Xu, Wei, Zheng, Cathy, Schuchter, Lynn M., Karakousis, Giorgos C., Mitchell, Tara C., Amaravadi, Ravi, Flowers, Ahron J., Gimotty, Phyllis A., Xiao, Min, Mills, Gordon, Herlyn, Meenhard, Dong, Haidong, Mitchell, Michael J., Kim, Junhyong, Xu, Xiaowei, Guo, Wei

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BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth by Wang, Tao, Xiao, Min, Ge, Yingbin, Krepler, Clemens, Belser, Eric, Lopez-Coral, Alfonso, Xu, Xiaowei, Zhang, Gao, Azuma, Rikka, Liu, Qin, Liu, Rui, Li, Ling, Amaravadi, Ravi K, Xu, Wei, Karakousis, Giorgos, Gangadhar, Tara C, Schuchter, Lynn M, Lieu, Melissa, Khare, Sanika, Halloran, Molly B, Herlyn, Meenhard, Kaufman, Russel E

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Inhibition of Age-Related Therapy Resistance in Melanoma by Rosiglitazone-Mediated Induction of Klotho by Behera, Reeti, Kaur, Amanpreet, Webster, Marie R, Kim, Suyeon, Ndoye, Abibatou, Kugel, 3rd, Curtis H, Alicea, Gretchen M, Wang, Joshua, Ghosh, Kanad, Cheng, Phil, Lisanti, Sofia, Marchbank, Katie, Dang, Vanessa, Levesque, Mitchell, Dummer, Reinhard, Xu, Xiaowei, Herlyn, Meenhard, Aplin, Andrew E, Roesch, Alexander, Caino, Cecilia, Altieri, Dario C, Weeraratna, Ashani T

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MFF Regulation of Mitochondrial Cell Death Is a Therapeutic Target in Cancer by Seo, Jae Ho, Chae, Young Chan, Kossenkov, Andrew V, Lee, Yu Geon, Tang, Hsin-Yao, Agarwal, Ekta, Gabrilovich, Dmitry I, Languino, Lucia R, Speicher, David W, Shastrula, Prashanth K, Storaci, Alessandra Maria, Ferrero, Stefano, Gaudioso, Gabriella, Caroli, Manuela, Tosi, Davide, Giroda, Massimo, Vaira, Valentina, Rebecca, Vito W, Herlyn, Meenhard, Xiao, Min, Fingerman, Dylan, Martorella, Alessandra, Skordalakes, Emmanuel, Altieri, Dario C

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Melanoma chemotherapy leads to the selection of ABCB5-expressing cells by Chartrain, Marine, Riond, Joëlle, Stennevin, Aline, Vandenberghe, Isabelle, Gomes, Bruno, Lamant, Laurence, Meyer, Nicolas, Gairin, Jean Edouard, Guilbaud, Nicolas, Annereau, Jean Philippe

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Cell state dependent effects of Bmal1 on melanoma immunity and tumorigenicity by Zhang, Xue, Pant, Shishir M., Ritch, Cecily C., Tang, Hsin-Yao, Shao, Hongguang, Dweep, Harsh, Gong, Yao-Yu, Brooks, Rebekah, Brafford, Patricia, Wolpaw, Adam J., Lee, Yool, Weeraratna, Ashani, Sehgal, Amita, Herlyn, Meenhard, Kossenkov, Andrew, Speicher, David, Sorger, Peter K., Santagata, Sandro, Dang, Chi V.

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Discovery of a Selective Inhibitor of Oncogenic B-Raf Kinase with Potent Antimelanoma Activity by Tsai, James, Lee, John T., Wang, Weiru, Zhang, Jiazhong, Cho, Hanna, Mamo, Shumeye, Bremer, Ryan, Gillette, Sam, Kong, Jun, Haass, Nikolas K., Sproesser, Katrin, Li, Ling, Smalley, Keiran S. M., Fong, Daniel, Zhu, Yong-Liang, Marimuthu, Adhirai, Nguyen, Hoa, Lam, Billy, Liu, Jennifer, Cheung, Ivana, Rice, Julie, Suzuki, Yoshihisa, Luu, Catherine, Settachatgul, Calvin, Shellooe, Rafe, Cantwell, John, Kim, Sung-Hou, Schlessinger, Joseph, Zhang, Kam Y. J., West, Brian L., Powell, Ben, Habets, Gaston, Zhang, Chao, Ibrahim, Prabha N., Hirth, Peter, Artis, Dean R., Herlyn, Meenhard, Bollag, Gideon

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Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2 by O'Connell, Michael P, Marchbank, Katie, Webster, Marie R, Valiga, Alexander A, Kaur, Amanpreet, Vultur, Adina, Li, Ling, Herlyn, Meenhard, Villanueva, Jessie, Liu, Qin, Yin, Xiangfan, Widura, Sandy, Nelson, Janelle, Ruiz, Nivia, Camilli, Tura C, Indig, Fred E, Flaherty, Keith T, Wargo, Jennifer A, Frederick, Dennie T, Cooper, Zachary A, Nair, Suresh, Amaravadi, Ravi K, Schuchter, Lynn M, Karakousis, Giorgos C, Xu, Wei, Xu, Xiaowei, Weeraratna, Ashani T

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Targeting Extracellular Matrix Remodeling Restores BRAF Inhibitor Sensitivity in BRAFi-resistant Melanoma by Marusak, Charles, Thakur, Varsha, Li, Yuan, Freitas, Juliano T, Zmina, Patrick M, Thakur, Vijay S, Chang, Mayland, Gao, Ming, Tan, Jiufeng, Xiao, Min, Lu, Yiling, Mills, Gordon B, Flaherty, Keith, Frederick, Dennie T, Miao, Benchun, Sullivan, Ryan J, Moll, Tabea, Boland, Genevieve M, Herlyn, Meenhard, Zhang, Gao, Bedogni, Barbara

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Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions by DiTullio, Richard A, Vassiliou, Leandros-Vassilios F, Karakaidos, Panagiotis, Kastrinakis, Nikolaos G, Halazonetis, Thanos D, Liloglou, Triantafillos, Yoneta, Akihiro, Kletsas, Dimitris, Kotsinas, Athanassios, Kittas, Christos, Zacharatos, Panayotis, Gorgoulis, Vassilis G, Herlyn, Meenhard, Venere, Monica, Levy, Brynn

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Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases by Smalley, Keiran S M, Haass, Nikolas K, Brafford, Patricia A, Lioni, Mercedes, Flaherty, Keith T, Herlyn, Meenhard

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Abstract IA01: Strategies for targeted and immune therapy in melanoma by Herlyn, Meenhard

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Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors by Yang, Ruifeng, Zheng, Ying, Li, Ling, Liu, Shujing, Burrows, Michelle, Wei, Zhi, Nace, Arben, Herlyn, Meenhard, Cui, Rutao, Guo, Wei, Cotsarelis, George, Xu, Xiaowei

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Co‐targeting BET and MEK as salvage therapy for MAPK and checkpoint inhibitor‐resistant melanoma by Echevarría‐Vargas, Ileabett M, Reyes‐Uribe, Patricia I, Guterres, Adam N, Yin, Xiangfan, Kossenkov, Andrew V, Liu, Qin, Zhang, Gao, Krepler, Clemens, Cheng, Chaoran, Wei, Zhi, Somasundaram, Rajasekharan, Karakousis, Giorgos, Xu, Wei, Morrissette, Jennifer JD, Lu, Yiling, Mills, Gordon B, Sullivan, Ryan J, Benchun, Miao, Frederick, Dennie T, Boland, Genevieve, Flaherty, Keith T, Weeraratna, Ashani T, Herlyn, Meenhard, Amaravadi, Ravi, Schuchter, Lynn M, Burd, Christin E, Aplin, Andrew E, Xu, Xiaowei, Villanueva, Jessie

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Oncogenic RAS Regulates Long Noncoding RNA Orilnc1 in Human Cancer by Zhang, Dongmei, Zhang, Gao, Hu, Xiaowen, Wu, Lawrence, Feng, Yi, He, Sidan, Zhang, Youyou, Hu, Zhongyi, Yang, Lu, Tian, Tian, Xu, Weiting, Wei, Zhi, Lu, Yiling, Flaherty, Keith T, Zhong, Xiaomin, Mills, Gordon B, Gimotty, Phyllis A, Xu, Xiaowei, Herlyn, Meenhard, Zhang, Lin

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Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence by Singleton, Katherine R., Crawford, Lorin, Tsui, Elizabeth, Manchester, Haley E., Maertens, Ophelia, Liu, Xiaojing, Liberti, Maria V., Magpusao, Anniefer N., Stein, Elizabeth M., Tingley, Jennifer P., Frederick, Dennie T., Boland, Genevieve M., Flaherty, Keith T., McCall, Shannon J., Krepler, Clemens, Sproesser, Katrin, Herlyn, Meenhard, Adams, Drew J., Locasale, Jason W., Cichowski, Karen, Mukherjee, Sayan, Wood, Kris C.

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HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation by Zhang, Wei, Yang, Jiegang, Wang, Beike, Lu, Youtao, Yang, Jingbo, Zhong, Wenqun, Yu, Ziyan, Qin, Zhiyuan, Xiao, Bolin, Wang, Kuiming, Ma, Yi Y., Amaravadi, Ravi, Herlyn, Meenhard, Kim, Junhyong, Xu, Xiaowei, Guo, Wei

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CDKN2B Loss Promotes Progression from Benign Melanocytic Nevus to Melanoma by McNeal, Andrew S, Liu, Kevin, Nakhate, Vihang, Natale, Christopher A, Duperret, Elizabeth K, Capell, Brian C, Dentchev, Tzvete, Berger, Shelley L, Herlyn, Meenhard, Seykora, John T, Ridky, Todd W

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Inhibition of endothelin-B receptor signaling synergizes with MAPK pathway inhibitors in BRAF mutated melanoma by Schäfer, Alexander, Haenig, Benedicte, Erupathil, Julie, Strickner, Panja, Sabato, Daniela, Welford, Richard W. D., Klaeylé, Lhéanna, Simon, Elise, Krepler, Clemens, Brafford, Patricia, Xiao, Min, Herlyn, Meenhard, Gstaiger, Matthias, Lehembre, Francois, Renz, Imke

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Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion by Grugan, Katharine D., Miller, Charles G., Yao, Yao, Michaylira, Carmen Z., Ohashi, Shinya, Klein-Szanto, Andres J., Diehl, J. Alan, Herlyn, Meenhard, Han, May, Nakagawa, Hiroshi, Rustgi, Anil K., Donahoe, Patricia K.

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