Exploring the Wnt Pathway as a Therapeutic Target for Prostate Cancer by Koushyar, Sarah, Meniel, Valerie S, Phesse, Toby J, Pearson, Helen B

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Genetic dissection of differential signaling threshold requirements for the Wnt/beta-catenin pathway in vivo by Buchert, Michael, Athineos, Dimitris, Abud, Helen E, Burke, Zoe D, Faux, Maree C, Samuel, Michael S, Jarnicki, Andrew G, Winbanks, Catherine E, Newton, Ian P, Meniel, Valerie S, Suzuki, Hiromu, Stacker, Steven A, Näthke, Inke S, Tosh, David, Huelsken, Joerg, Clarke, Alan R, Heath, Joan K, Sansom, Owen J, Ernst, Matthias

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Development and Characterisation of a New Patient-Derived Xenograft Model of AR-Negative Metastatic Castration-Resistant Prostate Cancer by Turnham, Daniel J, Mullen, Manisha S, Bullock, Nicholas P, Gilroy, Kathryn L, Richards, Anna E, Patel, Radhika, Quintela, Marcos, Meniel, Valerie S, Seaton, Gillian, Kynaston, Howard, Clarkson, Richard W E, Phesse, Toby J, Nelson, Peter S, Haffner, Michael C, Staffurth, John N, Pearson, Helen B

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B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver by Reed, Karen R, Athineos, Dimitris, Meniel, Valerie S, Wilkins, Julie A, Ridgway, Rachel A, Burke, Zoé D, Muncan, Vanesa, Clarke, Alan R, Sansom, Owen J

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Development of a low-seroprevalence, αvβ6 integrin-selective virotherapy based on human adenovirus type 10 by Bates, Emily A., Davies, James A., Váňová, Jana, Nestić, Davor, Meniel, Valerie S., Koushyar, Sarah, Cunliffe, Tabitha G., Mundy, Rosie M., Moses, Elise, Uusi-Kerttula, Hanni K., Baker, Alexander T., Cole, David K., Majhen, Dragomira, Rizkallah, Pierre J., Phesse, Toby, Chester, John D., Parker, Alan L.

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Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations by Flanagan, Dustin J, Barker, Nick, Costanzo, Natasha S Di, Mason, Elizabeth A, Gurney, Austin, Meniel, Valerie S, Koushyar, Sarah, Austin, Chloe R, Ernst, Matthias, Pearson, Helen B, Boussioutas, Alex, Clevers, Hans, Phesse, Toby J, Vincan, Elizabeth

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The αvβ6 integrin specific virotherapy, Ad5NULL-A20.FCU1, selectively delivers potent “in-tumour” chemotherapy to pancreatic ductal adenocarcinoma by Badder, Luned M., Davies, James A., Meniel, Valerie S., Marušková, Mahulena, Salvador-Barbero, Beatriz, Bayliss, Rebecca J., Phesse, Toby J., Hogan, Catherine, Parker, Alan L.

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A limited role for p53 in modulating the immediate phenotype of Apc loss in the intestine by Reed, Karen R, Meniel, Valerie S, Marsh, Victoria, Cole, Alicia, Sansom, Owen J, Clarke, Alan R

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Myc deletion rescues Apc deficiency in the small intestine by Wilkins, Julie A, Clevers, Hans, Reed, Karen R, Vass, J. Keith, Athineos, Dimitris, Muncan, Vanesa, Clarke, Alan R, Sansom, Owen J, Phesse, Toby J, Meniel, Valerie S

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Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth by Pearson, Helen B, Li, Jason, Meniel, Valerie S, Fennell, Christina M, Waring, Paul, Montgomery, Karen G, Rebello, Richard J, Macpherson, Arthi A, Koushyar, Sarah, Furic, Luc, Cullinane, Carleen, Clarkson, Richard W, Smalley, Matthew J, Simpson, Kaylene J, Phesse, Toby J, Shepherd, Peter R, Humbert, Patrick O, Sansom, Owen J, Phillips, Wayne A

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E-cadherin can limit the transforming properties of activating β-catenin mutations by Huels, David J, Ridgway, Rachel A, Radulescu, Sorina, Leushacke, Marc, Campbell, Andrew D, Biswas, Sujata, Leedham, Simon, Serra, Stefano, Chetty, Runjan, Moreaux, Guenievre, Parry, Lee, Matthews, James, Song, Fei, Hedley, Ann, Kalna, Gabriela, Ceteci, Fatih, Reed, Karen R, Meniel, Valerie S, Maguire, Aoife, Doyle, Brendan, Söderberg, Ola, Barker, Nick, Watson, Alastair, Larue, Lionel, Clarke, Alan R, Sansom, Owen J

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Proteomic profiling of a mouse model of acute intestinal Apc deletion leads to identification of potential novel biomarkers of human colorectal cancer (CRC) by Hammoudi, Abeer, Song, Fei, Reed, Karen R., Jenkins, Rosalind E., Meniel, Valerie S., Watson, Alastair J.M., Pritchard, D. Mark, Clarke, Alan R., Jenkins, John R.

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Matricellular protein SPARCL1 regulates tumor microenvironment-dependent endothelial cell heterogeneity in colorectal carcinoma by Naschberger, Elisabeth, Liebl, Andrea, Schellerer, Vera S, Schütz, Manuela, Britzen-Laurent, Nathalie, Kölbel, Patrick, Schaal, Ute, Haep, Lisa, Regensburger, Daniela, Wittmann, Thomas, Klein-Hitpass, Ludger, Rau, Tilman T, Dietel, Barbara, Méniel, Valérie S, Clarke, Alan R, Merkel, Susanne, Croner, Roland S, Hohenberger, Werner, Stürzl, Michael

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Matricellular Protein SPARCL1 Regulates Blood Vessel Integrity and Antagonizes Inflammatory Bowel Disease by Regensburger, Daniela, Tenkerian, Clara, Pürzer, Victoria, Schmid, Benjamin, Wohlfahrt, Thomas, Stolzer, Iris, López-Posadas, Rocío, Günther, Claudia, Waldner, Maximilian J, Becker, Christoph, Sticht, Heinrich, Petter, Katja, Flierl, Christian, Gass, Tobias, Thoenissen, Tim, Geppert, Carol I, Britzen-Laurent, Nathalie, Méniel, Valérie S, Ramming, Andreas, Stürzl, Michael, Naschberger, Elisabeth

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The αvβ6 integrin specific virotherapy, Ad5 NULL -A20.FCU1, selectively delivers potent "in-tumour" chemotherapy to pancreatic ductal adenocarcinoma by Badder, Luned M, Davies, James A, Meniel, Valerie S, Marušková, Mahulena, Salvador-Barbero, Beatriz, Bayliss, Rebecca J, Phesse, Toby J, Hogan, Catherine, Parker, Alan L

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Myc deletion rescues Apc deficiency in the small intestine by SANSOM, Owen J, MENIEL, Valerie S, MUNCAN, Vanesa, PHESSE, Toby J, WILKINS, Julie A, REED, Karen R, VASS, J. Keith, ATHINEOS, Dimitris, CLEVERS, Hans, CLARKE, Alan R

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E-cadherin can limit the transforming properties of activating [beta]-catenin mutations by Huels, David J, Ridgway, Rachel A, Radulescu, Sorina, Leushacke, Marc, Campbell, Andrew D, Biswas, Sujata, Leedham, Simon, Serra, Stefano, Chetty, Runjan, Moreaux, Guenievre, Parry, Lee, Matthews, James, Song, Fei, Hedley, Ann, Kalna, Gabriela, Ceteci, Fatih, Reed, Karen R, Meniel, Valerie S, Maguire, Aoife, Doyle, Brendan, Soderberg, Ola, Barker, Nick, Watson, Alastair, Larue, Lionel, Clarke, Alan R, Sansom, Owen J

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Genetic Dissection of Differential Signaling Threshold Requirements for the Wnt/[beta]-Catenin Pathway In Vivo: e1000816 by Buchert, Michael, Athineos, Dimitris, Abud, Helen E, Burke, Zoe D, Faux, Maree C, Samuel, Michael S, Jarnicki, Andrew G, Winbanks, Catherine E, Newton, Ian P, Meniel, Valerie S, Suzuki, Hiromu, Stacker, Steven A, Näthke, Inke S, Tosh, David, Huelsken, Joerg, Clarke, Alan R, Heath, Joan K, Sansom, Owen J, Ernst, Matthias

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The scaffolding protein flot2 promotes cytoneme-based transport of wnt3 in gastric cancer by Routledge, Daniel, Rogers, Sally, Ono, Yosuke, Brunt, Lucy, Meniel, Valerie, Tornillo, Giusy, Ashktorab, Hassan, Phesse, Toby J, Scholpp, Steffen

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Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling by Berenjeno, Inma M., Piñeiro, Roberto, Castillo, Sandra D., Pearce, Wayne, McGranahan, Nicholas, Dewhurst, Sally M., Meniel, Valerie, Birkbak, Nicolai J., Lau, Evelyn, Sansregret, Laurent, Morelli, Daniele, Kanu, Nnennaya, Srinivas, Shankar, Graupera, Mariona, Parker, Victoria E. R., Montgomery, Karen G., Moniz, Larissa S., Scudamore, Cheryl L., Phillips, Wayne A., Semple, Robert K., Clarke, Alan, Swanton, Charles, Vanhaesebroeck, Bart

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