588 A First-in-patient Phase I Study of the Novel Gamma Secretase Inhibitor PF-03084014 in Patients with Advanced Solid Tumor Malignancies by Messersmith, W.A, LoRusso, P.M, Cleary, J.M, Dasari, A, Huang, B, Shaik, N.M, Cesari, R, McLachlan, K.R, Kern, K.A, Shapiro, G.I

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Avelumab or talazoparib in combination with binimetinib in metastatic pancreatic ductal adenocarcinoma: dose-finding results from phase Ib of the JAVELIN PARP MEKi trial by Rodon Ahnert, J., Tan, D.S.-W., Garrido-Laguna, I., Harb, W., Bessudo, A., Beck, J.T., Rottey, S., Bahary, N., Kotecki, N., Zhu, Z., Deng, S., Kowalski, K., Wei, C., Pathan, N., Laliberte, R.J., Messersmith, W.A.

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366 A Phase 1 study of continuous dosing with PX-866, an irreversible, pan-isoform inhibitor of PI3 kinase by Jimeno, A, Herbst, R.S, Falchook, G.S, Messersmith, W.A, Camidge, D.R, Peterson, S.R, Hausman, D.F, Kurzrock, R, Eckhardt, S.G, Hong, D.S

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77 POSTER Prediction and in vivo validation of AZD0530 sensitivity by gene expression profiling in human pancreatic tumor xenografts by Rajeshkumar, N.V, Tan, A.C, Wheelhouse, J, Jimeno, A, Messersmith, W.A, Green, T.P, Hidalgo, M

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402 POSTER A phase I study of gemcitabine, capecitabine and vandetanib in patients with advanced solid tumors with an expanded cohort in biliary and pancreatic malignancies by Leong, S, Obryant, C.L, Messersmith, W.A, Diab, S, Kane, M.A, Nallapreddy, S, Weekes, C, Spratlin, J, Call, J, Eckhardt, S.G

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Connexin 43 gap junction proteins are up-regulated in remyelinating spinal cord by Roscoe, W.A., Messersmith, E., Meyer-Franke, A., Wipke, B., Karlik, S.J.

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