Long lasting neutralization of C5 by SKY59, a novel recycling antibody, is a potential therapy for complement-mediated diseases by Fukuzawa, Taku, Sampei, Zenjiro, Haraya, Kenta, Ruike, Yoshinao, Shida-Kawazoe, Meiri, Shimizu, Yuichiro, Gan, Siok Wan, Irie, Machiko, Tsuboi, Yoshinori, Tai, Hitoshi, Sakiyama, Tetsushi, Sakamoto, Akihisa, Ishii, Shinya, Maeda, Atsuhiko, Iwayanagi, Yuki, Shibahara, Norihito, Shibuya, Mitsuko, Nakamura, Genki, Nambu, Takeru, Hayasaka, Akira, Mimoto, Futa, Okura, Yuu, Hori, Yuji, Habu, Kiyoshi, Wada, Manabu, Miura, Takaaki, Tachibana, Tatsuhiko, Honda, Kiyofumi, Tsunoda, Hiroyuki, Kitazawa, Takehisa, Kawabe, Yoshiki, Igawa, Tomoyuki, Hattori, Kunihiro, Nezu, Junichi

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Exploitation of Elevated Extracellular ATP to Specifically Direct Antibody to Tumor Microenvironment by Mimoto, Futa, Tatsumi, Kanako, Shimizu, Shun, Kadono, Shojiro, Haraya, Kenta, Nagayasu, Miho, Suzuki, Yuki, Fujii, Etsuko, Kamimura, Masaki, Hayasaka, Akira, Kawauchi, Hiroki, Ohara, Kazuhiro, Matsushita, Masayuki, Baba, Takeshi, Susumu, Hiroaki, Sakashita, Takuya, Muraoka, Terushige, Aso, Kosuke, Katada, Hitoshi, Tanaka, Eriko, Nakagawa, Kenji, Hasegawa, Masami, Ayabe, Miho, Yamamoto, Tessai, Tanba, Shigero, Ishiguro, Takahiro, Kamikawa, Takayuki, Nambu, Takeru, Kibayashi, Tatsuya, Azuma, Yumiko, Tomii, Yasushi, Kato, Atsuhiko, Ozeki, Kazuhisa, Murao, Naoaki, Endo, Mika, Kikuta, Junichi, Kamata-Sakurai, Mika, Ishii, Masaru, Hattori, Kunihiro, Igawa, Tomoyuki

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Engineered monoclonal antibody with novel antigen-sweeping activity in vivo by Igawa, Tomoyuki, Maeda, Atsuhiko, Haraya, Kenta, Tachibana, Tatsuhiko, Iwayanagi, Yuki, Mimoto, Futa, Higuchi, Yoshinobu, Ishii, Shinya, Tamba, Shigero, Hironiwa, Naoka, Nagano, Kozue, Wakabayashi, Tetsuya, Tsunoda, Hiroyuki, Hattori, Kunihiro

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Novel asymmetrically engineered antibody Fc variant with superior FcγR binding affinity and specificity compared with afucosylated Fc variant by Mimoto, Futa, Igawa, Tomoyuki, Kuramochi, Taichi, Katada, Hitoshi, Kadono, Shojiro, Kamikawa, Takayuki, Shida-Kawazoe, Meiri, Hattori, Kunihiro

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MHC-associated peptide proteomics enabling highly sensitive detection of immunogenic sequences for the development of therapeutic antibodies with low immunogenicity by Sekiguchi, Nobuo, Kubo, Chiyomi, Takahashi, Ayako, Muraoka, Kumiko, Takeiri, Akira, Ito, Shunsuke, Yano, Mariko, Mimoto, Futa, Maeda, Atsuhiko, Iwayanagi, Yuki, Wakabayashi, Tetsuya, Takata, Shotaro, Murao, Naoaki, Chiba, Shuichi, Ishigai, Masaki

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Inhibitory FcγRIIb-Mediated Soluble Antigen Clearance from Plasma by a pH-Dependent Antigen-Binding Antibody and Its Enhancement by Fc Engineering by Iwayanagi, Yuki, Igawa, Tomoyuki, Maeda, Atsuhiko, Haraya, Kenta, Wada, Naoko A, Shibahara, Norihito, Ohmine, Ken, Nambu, Takeru, Nakamura, Genki, Mimoto, Futa, Katada, Hitoshi, Ito, Shunsuke, Tachibana, Tatsuhiko, Jishage, Kou-ichi, Hattori, Kunihiro

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Abstract 1872: A DLL3/CD3/CD137 trispecific T cell engager shows potent antitumor activity in small cell lung cancer models by Mikami, Hirofumi, Feng, Shu, Naoi, Sotaro, Azuma, Yumiko, Kayukawa, Yoko, Tsunenari, Toshiaki, Asanuma, Kentaro, Iwabuchi, Ryutaro, Nagano, Hiroaki, Shinozuka, Junko, Yamazaki, Masaki, Kuroi, Haruka, Gan, Siok Wan, Chichili, Priyanka, Shimizu, Shun, Matsuda, Yutaka, Ishii, Shinya, Kamikawaji, Shogo, Kinoshita, Yasuko, Shimizu, Yuichiro, Sakamoto, Akihisa, Muraoka, Masaru, Takahashi, Noriyuki, Kawa, Tatsuya, Shiraiwa, Hirotake, Kashima, Kenji, Mimoto, Futa, Kamata-Sakurai, Mika, Kitazawa, Takehisa, Igawa, Tomoyuki

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Engineered Monoclonal Antibody with Novel Antigen-Sweeping Activity In Vivo. e63236 by Igawa, Tomoyuki, Maeda, Atsuhiko, Haraya, Kenta, Tachibana, Tatsuhiko, Iwayanagi, Yuki, Mimoto, Futa, Higuchi, Yoshinobu, Ishii, Shinya, Tamba, Shigero, Hironiwa, Naoka

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A unique catalytic triad revealed by the crystal structure of APE0912, a short-chain dehydrogenase/reductase family protein from Aeropyrum pernix K1 by Yamamura, Akihiro, Ichimura, Takefumi, Mimoto, Futa, Ohtsuka, Jun, Miyazono, Ken-Ichi, Okai, Masahiko, Kamo, Masayuki, Lee, Woo-Cheol, Nagata, Koji, Tanokura, Masaru

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MHC-associated peptide proteomics enabling highly sensitive detection of immunogenic sequences for the development of therapeutic antibodies with low immunogenicity by Sekiguchi, Nobuo, Kubo, Chiyomi, Takahashi, Ayako, Muraoka, Kumiko, Takeiri, Akira, Ito, Shunsuke, Yano, Mariko, Mimoto, Futa, Maeda, Atsuhiko, Iwayanagi, Yuki, Wakabayashi, Tetsuya, Takata, Shotaro, Murao, Naoaki, Chiba, Shuichi, Ishigai, Masaki

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