Diastereoselective synthesis of fused cyclopropyl-3-amino-2,4-oxazine β-amyloid cleaving enzyme (BACE) inhibitors and their biological evaluation by Low, Jonathan D., Bartberger, Michael D., Cheng, Yuan, Whittington, Doug, Xue, Quifen, Wood, Stephen, Allen, Jennifer R., Minatti, Ana E.

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Discovery of a Covalent Inhibitor of KRAS G12C (AMG 510) for the Treatment of Solid Tumors by Lanman, Brian A, Allen, Jennifer R, Allen, John G, Amegadzie, Albert K, Ashton, Kate S, Booker, Shon K, Chen, Jian Jeffrey, Chen, Ning, Frohn, Michael J, Goodman, Guy, Kopecky, David J, Liu, Longbin, Lopez, Patricia, Low, Jonathan D, Ma, Vu, Minatti, Ana E, Nguyen, Thomas T, Nishimura, Nobuko, Pickrell, Alexander J, Reed, Anthony B, Shin, Youngsook, Siegmund, Aaron C, Tamayo, Nuria A, Tegley, Christopher M, Walton, Mary C, Wang, Hui-Ling, Wurz, Ryan P, Xue, May, Yang, Kevin C, Achanta, Pragathi, Bartberger, Michael D, Canon, Jude, Hollis, L Steven, McCarter, John D, Mohr, Christopher, Rex, Karen, Saiki, Anne Y, San Miguel, Tisha, Volak, Laurie P, Wang, Kevin H, Whittington, Douglas A, Zech, Stephan G, Lipford, J Russell, Cee, Victor J

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Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors by Lanman, Brian A, Allen, Jennifer R, Allen, John G, Amegadzie, Albert K, Ashton, Kate S, Booker, Shon K, Chen, Jian Jeffrey, Chen, Ning, Frohn, Michael J, Goodman, Guy, Kopecky, David J, Liu, Longbin, Lopez, Patricia, Low, Jonathan D, Ma, Vu, Minatti, Ana E, Nguyen, Thomas T, Nishimura, Nobuko, Pickrell, Alexander J, Reed, Anthony B, Shin, Youngsook, Siegmund, Aaron C, Tamayo, Nuria A, Tegley, Christopher M, Walton, Mary C, Wang, Hui-Ling, Wurz, Ryan P, Xue, May, Yang, Kevin C, Achanta, Pragathi, Bartberger, Michael D, Canon, Jude, Hollis, L. Steven, McCarter, John D, Mohr, Christopher, Rex, Karen, Saiki, Anne Y, San Miguel, Tisha, Volak, Laurie P, Wang, Kevin H, Whittington, Douglas A, Zech, Stephan G, Lipford, J. Russell, Cee, Victor J

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Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer’s disease by Chen, Jian Jeffrey, Liu, Qingyian, Yuan, Chester, Gore, Vijay, Lopez, Patricia, Ma, Vu, Amegadzie, Albert, Qian, Wenyuan, Judd, Ted C., Minatti, Ana E., Brown, James, Cheng, Yuan, Xue, May, Zhong, Wenge, Dineen, Thomas A., Epstein, Oleg, Human, Jason, Kreiman, Charles, Marx, Isaac, Weiss, Matthew M., Hitchcock, Stephen A., Powers, Timothy S., Chen, Kui, Wen, Paul H., Whittington, Douglas A., Cheng, Alan C., Bartberger, Michael D., Hickman, Dean, Werner, Jonathan A., Vargas, Hugo M., Everds, Nancy E., Vonderfecht, Steven L., Dunn, Robert T., Wood, Stephen, Fremeau, Robert T., White, Ryan D., Patel, Vinod F.

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Development of 2-aminooxazoline 3-azaxanthene β-amyloid cleaving enzyme (BACE) inhibitors with improved selectivity against Cathepsin D by Low, Jonathan D, Bartberger, Michael D, Chen, Kui, Cheng, Yuan, Fielden, Mark R, Gore, Vijay, Hickman, Dean, Liu, Qingyian, Allen Sickmier, E, Vargas, Hugo M, Werner, Jonathan, White, Ryan D, Whittington, Douglas A, Wood, Stephen, Minatti, Ana E

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Development of 2-aminooxazoline 3-azaxanthene β-amyloid cleaving enzyme (BACE) inhibitors with improved selectivity against Cathepsin DThe authors declare no competing interests.El... by Low, Jonathan D, Bartberger, Michael D, Chen, Kui, Cheng, Yuan, Fielden, Mark R, Gore, Vijay, Hickman, Dean, Liu, Qingyian, Allen Sickmier, E, Vargas, Hugo M, Werner, Jonathan, White, Ryan D, Whittington, Douglas A, Wood, Stephen, Minatti, Ana E

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Development of 2-aminooxazoline 3-azaxanthene β-amyloid cleaving enzyme (BACE) inhibitors with improved selectivity against Cathepsin D† †The authors declare no competing interests... by Low, Jonathan D., Bartberger, Michael D., Chen, Kui, Cheng, Yuan, Fielden, Mark R., Gore, Vijay, Hickman, Dean, Liu, Qingyian, Allen Sickmier, E., Vargas, Hugo M., Werner, Jonathan, White, Ryan D., Whittington, Douglas A., Wood, Stephen, Minatti, Ana E.

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