Transformation of the Fallopian Tube Secretory Epithelium Leads to High-Grade Serous Ovarian Cancer in Brca;Tp53;Pten Models by Perets, Ruth, Wyant, Gregory A., Muto, Katherine W., Bijron, Jonathan G., Poole, Barish B., Chin, Kenneth T., Chen, Jin Yun H., Ohman, Anders W., Stepule, Corey D., Kwak, Soongu, Karst, Alison M., Hirsch, Michelle S., Setlur, Sunita R., Crum, Christopher P., Dinulescu, Daniela M., Drapkin, Ronny

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Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy by McAuliffe, Shannon M, Morgan, Stefanie L, Wyant, Gregory A, Tran, Lieu T, Muto, Katherine W, Chen, Yu Sarah, Chin, Kenneth T, Partridge, Justin C, Poole, Barish B, Cheng, Kuang-Hung, Daggett, John, Cullen, Kristen, Kantoff, Emily, Hasselbatt, Kathleen, Berkowitz, Julia, Muto, Michael G, Berkowitz, Ross S, Aster, Jon C, Matulonis, Ursula A, Dinulescu, Daniela M

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Harnessing structure-activity relationship to engineer a cisplatin nanoparticle for enhanced antitumor efficacy by Paraskar, Abhimanyu S., Soni, Shivani, Chin, Kenneth T., Chaudhuri, Padmaparna, Muto, Katherine W., Berkowitz, Julia, Handlogten, Michael W., Alves, Nathan J., Bilgicer, Basar, Dinulescu, Daniela M., Mashelkar, Raghunath A., Sengupta, Shiladitya

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Cholesterol-tethered platinum II-based supramolecular nanoparticle increases antitumor efficacy and reduces nephrotoxicity by Sengupta, Poulomi, Basu, Sudipta, Soni, Shivani, Pandey, Ambarish, Roy, Bhaskar, Oh, Michael S, Chin, Kenneth T, Paraskar, Abhimanyu S, Sarangi, Sasmit, Connor, Yamicia, Sabbisetti, Venkata S, Kopparam, Jawahar, Kulkarni, Ashish, Muto, Katherine, Amarasiriwardena, Chitra, Jayawardene, Innocent, Lupoli, Nicola, Dinulescu, Daniela M, Bonventre, Joseph V, Mashelkar, Raghunath A, Sengupta, Shiladitya

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Abstract 1951: Targeting cancer by a chimeric nanoparticle formulation of Cisplatin and PI828, a PI3 kinase inhibitor by Roy, Bhaskar, Sengupta, Poulomi, Dinulescu, Daniela, Muto, Katherine, Papa, Anne Laure, Basu, Sudipta, Sengupta, Shiladitya

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Abstract PR01: Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in BRCA/P53 models by Wyant, Gregory A, Perets, Ruth, Muto, Katherine, Poole, Barish B., Chen, Jin YH, Ohman, Anders W, Setlur, Sunita R, Crum, Christopher P., Drapkin, Ronny, Dinulescu, Daniela M.

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Abstract 3292: A genetically engineered mouse model for high grade serous “ovarian” carcinoma arising in the fallopian tube by Perets, Ruth, Muto, Katherine W., Bijron, Jonathan G., Kenneth, Chin T., Poole, Barish B., Crum, Christopher P., Dinulescu, Daniela M., Drapkin, Ronny

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Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapy by McAuliffe, Shannon M., Morgan, Stefanie L., Wyant, Gregory A., Tran, Lieu T., Muto, Katherine W., Chen, Yu Sarah, Chin, Kenneth T., Partridge, Justin C., Poole, Barish B., Cheng, Kuang-Hung, Daggett, John, Cullen, Kristen, Kantoff, Emily, Hasselbatt, Kathleen, Berkowitz, Julia, Muto, Michael G., Berkowitz, Ross S., Aster, Jon C., Matulonis, Ursula A., Dinulescu, Daniela M.

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Spearmint ( l -Carvone) Oil and Wintergreen (Methyl Salicylate) Oil Emulsion Is an Effective Immersion Anesthetic of Fishes by Danner, G. Russell, Muto, Katherine W., Zieba, Anna M., Stillman, Chelsea M., Seggio, Joseph A., Ahmad, S. Tariq

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Enhanced Efficacy of Simultaneous PD-1 and PD-L1 Immune Checkpoint Blockade in High-Grade Serous Ovarian Cancer by Wan, Changxin, Keany, Matthew P, Dong, Han, Al-Alem, Linah F, Pandya, Unnati M, Lazo, Suzan, Boehnke, Karsten, Lynch, Katherine N, Xu, Rui, Zarrella, Dominique T, Gu, Shengqing, Cejas, Paloma, Lim, Klothilda, Long, Henry W, Elias, Kevin M, Horowitz, Neil S, Feltmate, Colleen M, Muto, Michael G, Worley, Jr, Michael J, Berkowitz, Ross S, Matulonis, Ursula A, Nucci, Marisa R, Crum, Christopher P, Rueda, Bo R, Brown, Myles, Liu, Xiaole Shirley, Hill, Sarah J

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Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation by Malta, Tathiane M., Gentles, Andrew J., Weinstein, John N., Czerwińska, Patrycja, Heyn, Holger, Godwin, Andrew K., Zhang, Jiashan (Julia), Wu, Ye, Liu, Yuexin, Reynolds, Sheila, Akbani, Rehan, Kanchi, Rupa S., Ladanyi, Marc, Peto, Myron, Bowlby, Reanne, Schein, Jacqueline E., Sipahimalani, Payal, Thiessen, Nina, Cope, Leslie, Weisenberger, Daniel J., Hoyle, Alan P., Mieczkowski, Piotr A., Shi, Yan, Veluvolu, Umadevi, Zhou, Wanding, Bellair, Michelle, Creighton, Chad J., Gibbs, Richard A., Li, Wei, Xi, Liu, Zhao, Fengmei, Mardis, Elaine R., Paulauskis, Joseph, Eschbacher, Jennifer, Ittmann, Michael, Le, Xuan, Thorp, Richard, Lyadov, Vladimir, Setdikova, Galiya, Raut, Chandrajit P., Barrett, Wendi, Karlan, Beth Y., Hu, Hai, Bennett, Joseph, Chabot, John, Hibshoosh, Hanina, Potapova, Olga, Voronina, Olga, Berchuck, Andrew, McCall, Shannon, Olson, Jeffrey J., Ramalingam, Suresh, Stoop, Hans, Guillermo, Armando López, Castle, Erik, Kopp, Karla, Roberts, Lewis, Stanton, Melissa, Yang, Ju Dong, Broaddus, Russell, Guo, Charles, Moran, Cesar, Tamboli, Pheroze, Thompson, Timothy, Tsao, Anne, Wistuba, Ignacio, Haydu, Lauren, Saw, Robyn, Scolyer, Richard, Thompson, John, Reuter, Victor, Drwiega, Paul, Hung, Nguyen Phi, Pass, Harvey, Gorincioi, Ghenadie, Gilbert, Sebastien, Tamakawa, Raina, Chevalier, Simone, Morrison, Carl, Borgia, Jeffrey A., Junker, Kerstin, Bragazzi, Maria Consiglia, Moiseenko, Fedor, Duell, Rebecca, Pilarski, Robert, Senecal, Kelly, Henderson, Joel, Schadendorf, Dirk, Olabode, Oluwole, Nelson, Mark, Roggin, Kevin, Carey, Francis, Carney, Michael, Hernandez, Brenda, Walker, Joan, Valdivieso, Federico, Luketich, James, Tirapelli, Daniela, Catto, James, Kovatich, Albert J.

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The Shadow Knows: Using Shadows to Investigate the Structure of the Pretransitional Disk of HD 100453 by Long, Zachary C., Fernandes, Rachel B., Sitko, Michael, Wagner, Kevin, Muto, Takayuki, Hashimoto, Jun, Follette, Katherine, Grady, Carol A., Fukagawa, Misato, Hasegawa, Yasuhiro, Kluska, Jacques, Kraus, Stefan, Mayama, Satoshi, McElwain, Michael W., Oh, Daehyon, Tamura, Motohide, Uyama, Taichi, Wisniewski, John P., Yang, Yi

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Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas by Kim, Jaegil, Mishra, Lopa, Wang, Zhining, Liu, Jia, Getz, Gad, Lawrence, Michael S., Saksena, Gordon, Voet, Doug, Zhang, Wei, Hegde, Apurva M., Korkut, Anil, Sanchez-Vega, Francisco, Sander, Chris, Schultz, Nikolaus, Stuart, Joshua M., Parker, Joel S., Ally, Adrian, Carlsen, Rebecca, Kasaian, Katayoon, Ma, Yussanne, Marra, Marco A., Berger, Ashton C., Cherniack, Andrew D., Shih, Juliann, Kucherlapati, Melanie H., Maglinte, Dennis T., Hale, Walker, Korchina, Viktoriya, Morgan, Margaret, Santibanez, Jireh, Wang, Linghua, Wheeler, David A., Fulton, Robert S., Thompson, Eric, Bowen, Jay, Gerken, Mark, Leraas, Kristen M., Reis, Rui M., Kohl, Bernard, Berkowitz, Ross, Malykh, Andrei, Fulop, Jordonna, Sloan, Andrew E., Larson, Caroline, Iacocca, Mary, Roman-Roman, Sergio, Stern, Marc-Henri, Cheng, Feixiong, Delman, Keith, Maithel, Shishir, Chen, Chu, Stoehr, Robert, Edenfield, W. Jeffrey, Bubley, Glenn, De Rienzo, Assunta, Richards, William G., Kalkanis, Steven, Scarpace, Lisa, Martignetti, John A., Borad, Mitesh, O’Neill, Brian Patrick, Que, Florencia, Smyrk, Thomas, Esmaeli, Bita, Sood, Anil, Kakavand, Hojabr, Mann, Graham, Gopalan, Anuradha, Singh, Bhuvanesh, Miller, Judy, Yang, Hannah, Melamed, Jonathan, Caraman, Irina, Clipca, Adrian, Mura, Sergiu, Albert, Monique, Bartlett, John, Urba, Walter, Raymond, Daniel, Kumar, Bahavna, Sexton, Katherine C., Fassnacht, Martin, Graefen, Markus, Tennstedt, Pierre, Kendler, Ady, Campos, Benito, Jacobus, Laura, Adebamowo, Sally N., Giordano, Thomas, Mes-Masson, Anne-Marie, Moore, Kathleen, Moxley, Katherine, Pinero, Edna M. Mora, Dos Santos, Jose Sebastião, Agnew, Kathy, Godwin, Eryn M., Shipman, Cassaundra, Carey, Thomas, Wolf, Gregory, Van Tine, Brian

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lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer by Li, Song, Wan, Yunhu, Wu, Ye, Akbani, Rehan, Rao, Arvind, Luna, Augustin, Phillips, Sarah M., Sumer, S. Onur, Spellman, Paul, Benz, Christopher, Dhalla, Noreen, Holt, Robert, Sadeghi, Sara, Sipahimalani, Payal, Thiessen, Nina, Van Den Berg, David J., Perou, Charles M., Simons, Janae V., Doddapaneni, HarshaVardhan, Li, Wei, Bailey, Matthew, Ding, Li, Mallery, David, Shelton, Troy, Gastier-Foster, Julie M., Zmuda, Erik, Corcoran, Niall, Eschbacher, Jennifer, Noss, Ardene, Andry, Chris, Raut, Chandrajit P., Barrett, Wendi, De Rose, Agostino, Giuliante, Felice, Hagedorn, Curt H., Bennett, Joseph, Rabeno, Brenda, Swanson, Patricia, Staugaitis, Susan M., Chabot, John, Potapova, Olga, Secord, Angeles, Hanh, Phan Thi, Juhl, Hartmut, Akeredolu, Teniola, Birrer, Michael, Flotte, Thomas, Ho, Thai, Roberts, Lewis, Stanton, Melissa, Yang, Ju Dong, Gonzalez, Ana Maria Angulo, Bondaruk, Jolanta, Fujimoto, Junya, Gershenwald, Jeffrey, Lazar, Alexander J., Meric-Bernstam, Funda, Moran, Cesar, Synott, Maria, Wilmott, James, Reuter, Victor, Nair, Praveen, Metwalli, Adam R., Schmidt, Laura S., Vocke, Cathy D., Cernat, Mircea, Chemencedji, Inga, Pirtac, Maria, Alexopoulou, Iakovina, Tamakawa, Raina, Timmers, Henri, Schilero, Cathy, Smolenski, Kathy, Manikhas, George, Alvaro, Domenico, Chesla, David, Moiseenko, Fedor, Aziz, Dina, Elder, J. Bradley, Mandt, Randy, Wakely, Paul, Powers, James, Chan, June M., Landen, Charles N., Roggin, Kevin, Hernandez, Brenda, Unterberg, Andreas, Knudson, Michael, Knutson, Tina, Godwin, Andrew K., Bocklage, Therese, Postier, Russel, Zuna, Rosemary, Feldman, Michael, Dhir, Rajiv, Tirapelli, Daniela, Catto, James, Shelley, Carl Simon, Fong, Kwun M., Shriver, Craig D.

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Near-infrared Imaging of a Spiral in the CQ Tau Disk by Uyama, Taichi, Muto, Takayuki, Mawet, Dimitri, Christiaens, Valentin, Hashimoto, Jun, Kudo, Tomoyuki, Kuzuhara, Masayuki, Ruane, Garreth, Beichman, Charles, Absil, Olivier, Akiyama, Eiji, Bae, Jaehan, Bottom, Michael, Choquet, Elodie, Currie, Thayne, Dong, Ruobing, Follette, Katherine B., Fukagawa, Misato, Guidi, Greta, Huby, Elsa, Kwon, Jungmi, Mayama, Satoshi, Meshkat, Tiffany, Reggiani, Maddalena, Ricci, Luca, Serabyn, Eugene, Tamura, Motohide, Testi, Leonardo, Wallack, Nicole, Williams, Jonathan, Zhu, Zhaohuan

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A novel classification of residual disease after interval debulking surgery for advanced-stage ovarian cancer to better distinguish oncologic outcome by Manning-Geist, Beryl L., Hicks-Courant, Katherine, Gockley, Allison A., Clark, Rachel M., Del Carmen, Marcela G., Growdon, Whitfield B., Horowitz, Neil S., Berkowitz, Ross S., Muto, Michael G., Worley, Michael J.

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Moving beyond “complete surgical resection” and “optimal”: Is low-volume residual disease another option for primary debulking surgery? by Manning-Geist, Beryl L., Hicks-Courant, Katherine, Gockley, Allison A., Clark, Rachel M., del Carmen, Marcela G., Growdon, Whitfield B., Horowitz, Neil S., Berkowitz, Ross S., Muto, Michael G., Worley, Michael J.

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RECOVERY OF THE CANDIDATE PROTOPLANET HD 100546 b WITH GEMINI/NICI AND DETECTION OF ADDITIONAL (PLANET-INDUCED?) DISK STRUCTURE AT SMALL SEPARATIONS by Currie, Thayne, Muto, Takayuki, Kudo, Tomoyuki, Honda, Mitsuhiko, Brandt, Timothy D, Grady, Carol, Fukagawa, Misato, Burrows, Adam, Janson, Markus, Kuzuhara, Masayuki

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Enhanced Efficacy of Aurora Kinase Inhibitors in G2/M Checkpoint Deficient TP53 Mutant Uterine Carcinomas Is Linked to the Summation of LKB1–AKT–p53 Interactions by Lynch, Katherine N., Liu, Joyce F., Kesten, Nikolas, Chow, Kin-Hoe, Shetty, Aniket, He, Ruiyang, Afreen, Mosammat Faria, Yuan, Liping, Matulonis, Ursula A., Growdon, Whitfield B., Muto, Michael G., Horowitz, Neil S., Feltmate, Colleen M., Worley, Michael J., Berkowitz, Ross S., Crum, Christopher P., Rueda, Bo R., Hill, Sarah J.

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SEEDS ADAPTIVE OPTICS IMAGING OF THE ASYMMETRIC TRANSITION DISK OPH IRS 48 IN SCATTERED LIGHT by Follette, Katherine B, Grady, Carol A, Swearingen, Jeremy R, Sitko, Michael L, Champney, Elizabeth H, van der Marel, Nienke, Takami, Michihiro, Kuchner, Marc J, Close, Laird M, Muto, Takayuki

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