Discovery and Preclinical Pharmacology of a Novel, Potent, Nonsteroidal Estrogen Receptor Agonist/Antagonist, CP-336156, a Diaryltetrahydronaphthalene by Rosati, Robert L, Da Silva Jardine, Paul, Cameron, Kimberly O, Thompson, David D, Ke, Hua Zhu, Toler, Steven M, Brown, Thomas A, Pan, Lydia C, Ebbinghaus, Charles F, Reinhold, Anthony R, Elliott, Nancy C, Newhouse, Bradley N, Tjoa, Christina M, Sweetnam, Paul M, Cole, Mark J, Arriola, Mark W, Gauthier, Jeffrey W, Crawford, D. Todd, Nickerson, David F, Pirie, Christine M, Qi, Hong, Simmons, Hollis A, Tkalcevic, George T

Get full text

Monitoring the quality of conduct of clinical trials: a survey of current practices by Morrison, Briggs W, Cochran, Chrissy J, White, Jennifer Giangrande, Harley, Joan, Kleppinger, Cynthia F, Liu, An, Mitchel, Jules T, Nickerson, David F, Zacharias, Cynthia R, Kramer, Judith M, Neaton, James D

Get full text

Pyrazolinone-piperidine dipeptide growth hormone secretagogues (GHSs): Discovery of capromorelin by Carpino, Philip A, Lefker, Bruce A, Toler, Steven M, Pan, Lydia C, Hadcock, John R, Cook, Ewell R, DiBrino, Joseph N, Campeta, Anthony M, DeNinno, Shari L, Chidsey-Frink, Kristin L, Hada, William A, Inthavongsay, John, Mangano, F.Michael, Mullins, Michelle A, Nickerson, David F, Ng, Oicheng, Pirie, Christine M, Ragan, John A, Rose, Colin R, Tess, David A, Wright, Ann S, Yu, Li, Zawistoski, Michael P, DaSilva-Jardine, Paul A, Wilson, Theresa C, Thompson, David D

Get full text

Discovery and biological characterization of capromorelin analogues with extended half-lives by Carpino, Philip A., Lefker, Bruce A., Toler, Steven M., Pan, Lydia C., Hadcock, John R., Murray, Marianne C., Cook, Ewell R., DiBrino, Joseph N., DeNinno, Shari L., Chidsey-Frink, Kristin L., Hada, William A., Inthavongsay, John, Lewis, Sharon K., Mangano, F.Michael, Mullins, Michelle A., Nickerson, David F., Ng, Oicheng, Pirie, Christine M., Ragan, John A., Rose, Colin R., Tess, David A., Wright, Ann S., Yu, Li, Zawistoski, Michael P., Pettersen, John C., DaSilva-Jardine, Paul A., Wilson, Theresa C., Thompson, David D.

Get full text

Theoretical study of cis-trans isomerization in simple transition-metal complexes by Marynick, Dennis S, Askari, Sasan, Nickerson, David F

Get full text

Binding of Fluvastatin to Blood Cells and Plasma Proteins by Tse, Francis L.S., Nickerson, David F., Yardley, William S.

Get full text

Pyrazolinone-piperidine dipeptide growth hormone secretagogues (GHSs) by Carpino, Philip A, Lefker, Bruce A, Toler, Steven M, Pan, Lydia C, Hadcock, John R, Cook, Ewell R, DiBrino, Joseph N, Campeta, Anthony M, DeNinno, Shari L, Chidsey-Frink, Kristin L, Hada, William A, Inthavongsay, John, Mangano, F.Michael, Mullins, Michelle A, Nickerson, David F, Ng, Oicheng, Pirie, Christine M, Ragan, John A, Rose, Colin R, Tess, David A, Wright, Ann S, Yu, Li, Zawistoski, Michael P, DaSilva-Jardine, Paul A, Wilson, Theresa C, Thompson, David D

Get full text

First-pass metabolism and biliary recirculation of droloxifene in the female Sprague- Dawley rat by NICKERSON, DAVID F., TESS, DAVID A., TOLER, STEVEN M.

Get full text

Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants by Fu, Wenqing, O’Connor, Timothy D., Jun, Goo, Kang, Hyun Min, Abecasis, Goncalo, Leal, Suzanne M., Gabriel, Stacey, Rieder, Mark J., Altshuler, David, Shendure, Jay, Nickerson, Deborah A., Bamshad, Michael J., NHLBI Exome Sequencing Project, Akey, Joshua M.

Get full text

Recurrent Gain-of-Function Mutation in PRKG1 Causes Thoracic Aortic Aneurysms and Acute Aortic Dissections by Guo, Dong-chuan, Regalado, Ellen, Casteel, Darren E., Santos-Cortez, Regie L., Gong, Limin, Kim, Jeong Joo, Dyack, Sarah, Horne, S. Gabrielle, Chang, Guijuan, Jondeau, Guillaume, Boileau, Catherine, Coselli, Joseph S., Li, Zhenyu, Leal, Suzanne M., Shendure, Jay, Rieder, Mark J., Bamshad, Michael J., Nickerson, Deborah A., Kim, Choel, Milewicz, Dianna M.

Get full text

An overview of the CellML API and its implementation by Miller, Andrew K, Marsh, Justin, Reeve, Adam, Garny, Alan, Britten, Randall, Halstead, Matt, Cooper, Jonathan, Nickerson, David P, Nielsen, Poul F

Get full text

Pathogenic Variants for Mendelian and Complex Traits in Exomes of 6,517 European and African Americans: Implications for the Return of Incidental Results by Tabor, Holly K., Auer, Paul L., Jamal, Seema M., Chong, Jessica X., Yu, Joon-Ho, Gordon, Adam S., Graubert, Timothy A., O’Donnell, Christopher J., Rich, Stephen S., Nickerson, Deborah A., Bamshad, Michael J.

Get full text

The Physiome Model Repository 2 by YU, Tommy, LLOYD, Catherine M, NIELSEN, Poul M. F, NICKERSON, David P, COOLING, Michael T, MILLET, Andrew K, GARNY, Alan, TERKILDSEN, Jonna R, LAWSON, James, BRITTEN, Randall D, HUNTER, Peter J

Get full text

Improved Identification of von Hippel-Lindau Gene Alterations in Clear Cell Renal Tumors by Nickerson, Michael L, Jaeger, Erich, Shi, Yangu, Durocher, Jeffrey A, Mahurkar, Sunil, Zaridze, David, Matveev, Vsevolod, Janout, Vladimir, Kollarova, Hellena, Bencko, Vladimir, Navratilova, Marie, Szeszenia-Dabrowska, Neonilia, Mates, Dana, Mukeria, Anush, Holcatova, Ivana, Schmidt, Laura S, Toro, Jorge R, Karami, Sara, Hung, Rayjean, Gerard, Gary F, Linehan, W Marston, Merino, Maria, Zbar, Berton, Boffetta, Paolo, Brennan, Paul, Rothman, Nathaniel, Chow, Wong-Ho, Waldman, Frederic M, Moore, Lee E

Get full text

Periodontal Ehlers-Danlos Syndrome Is Caused by Mutations in C1R and C1S, which Encode Subcomponents C1r and C1s of Complement by Kapferer-Seebacher, Ines, Pepin, Melanie, Werner, Roland, Aitman, Timothy J., Nordgren, Ann, Stoiber, Heribert, Thielens, Nicole, Gaboriaud, Christine, Amberger, Albert, Schossig, Anna, Gruber, Robert, Giunta, Cecilia, Bamshad, Michael, Björck, Erik, Chen, Christina, Chitayat, David, Dorschner, Michael, Schmitt-Egenolf, Marcus, Hale, Christopher J., Hanna, David, Hennies, Hans Christian, Heiss-Kisielewsky, Irene, Lindstrand, Anna, Lundberg, Pernilla, Mitchell, Anna L., Nickerson, Deborah A., Reinstein, Eyal, Rohrbach, Marianne, Romani, Nikolaus, Schmuth, Matthias, Silver, Rachel, Taylan, Fulya, Vandersteen, Anthony, Vandrovcova, Jana, Weerakkody, Ruwan, Yang, Margaret, Pope, F. Michael, Aleck, Kirk, Banki, Zoltan, Dudas, Joszef, Dumfahrt, Herbert, Haririan, Hady, Hartsfield, James K., Kagen, Charles N., Lindert, Uschi, Meitinger, Thomas, Posch, Wilfried, Pritz, Christian, Ross, David, Schroer, Richard J., Wick, Georg, Wildin, Robert, Wilflingseder, Doris, Byers, Peter H., Zschocke, Johannes

Get full text

Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide by Walpole, Sebastian, Pritchard, Antonia L, Cebulla, Colleen M, Pilarski, Robert, Stautberg, Meredith, Davidorf, Frederick H, de la Fouchardière, Arnaud, Cabaret, Odile, Golmard, Lisa, Stoppa-Lyonnet, Dominique, Garfield, Erin, Njauw, Ching-Ni, Cheung, Mitchell, Turunen, Joni A, Repo, Pauliina, Järvinen, Reetta-Stiina, van Doorn, Remco, Jager, Martine J, Luyten, Gregorius P M, Marinkovic, Marina, Chau, Cindy, Potrony, Miriam, Höiom, Veronica, Helgadottir, Hildur, Pastorino, Lorenza, Bruno, William, Andreotti, Virginia, Dalmasso, Bruna, Ciccarese, Giulia, Queirolo, Paola, Mastracci, Luca, Wadt, Karin, Kiilgaard, Jens Folke, Speicher, Michael R, van Poppelen, Natasha, Kilic, Emine, Al-Jamal, Rana'a T, Dianzani, Irma, Betti, Marta, Bergmann, Carsten, Santagata, Sandro, Dahiya, Sonika, Taibjee, Saleem, Burke, Jo, Poplawski, Nicola, O'Shea, Sally J, Newton-Bishop, Julia, Adlard, Julian, Adams, David J, Lane, Anne-Marie, Kim, Ivana, Klebe, Sonja, Racher, Hilary, Harbour, J William, Nickerson, Michael L, Murali, Rajmohan, Palmer, Jane M, Howlie, Madeleine, Symmons, Judith, Hamilton, Hayley, Warrier, Sunil, Glasson, William, Johansson, Peter, Robles-Espinoza, Carla Daniela, Ossio, Raul, de Klein, Annelies, Puig, Susana, Ghiorzo, Paola, Nielsen, Maartje, Kivelä, Tero T, Tsao, Hensin, Testa, Joseph R, Gerami, Pedram, Stern, Marc-Henri, Paillerets, Brigitte Bressac-de, Abdel-Rahman, Mohamed H, Hayward, Nicholas K

Get full text

Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype by Sawyer, Sarah L, Tian, Lei, Kähkönen, Marketta, Schwartzentruber, Jeremy, Kircher, Martin, Majewski, Jacek, Dyment, David A, Innes, A Micheil, Boycott, Kym M, Moreau, Lisa A, Moilanen, Jukka S, Greenberg, Roger A

Get full text

Association of Arrhythmia-Related Genetic Variants With Phenotypes Documented in Electronic Medical Records by Van Driest, Sara L, Wells, Quinn S, Stallings, Sarah, Bush, William S, Gordon, Adam, Nickerson, Deborah A, Kim, Jerry H, Crosslin, David R, Jarvik, Gail P, Carrell, David S, Ralston, James D, Larson, Eric B, Bielinski, Suzette J, Olson, Janet E, Ye, Zi, Kullo, Iftikhar J, Abul-Husn, Noura S, Scott, Stuart A, Bottinger, Erwin, Almoguera, Berta, Connolly, John, Chiavacci, Rosetta, Hakonarson, Hakon, Rasmussen-Torvik, Laura J, Pan, Vivian, Persell, Stephen D, Smith, Maureen, Chisholm, Rex L, Kitchner, Terrie E, He, Max M, Brilliant, Murray H, Wallace, John R, Doheny, Kimberly F, Shoemaker, M. Benjamin, Li, Rongling, Manolio, Teri A, Callis, Thomas E, Macaya, Daniela, Williams, Marc S, Carey, David, Kapplinger, Jamie D, Ackerman, Michael J, Ritchie, Marylyn D, Denny, Joshua C, Roden, Dan M

Get full text

Polymorphisms within the C-Reactive Protein (CRP) Promoter Region Are Associated with Plasma CRP Levels by Carlson, Christopher S., Aldred, Shelley Force, Lee, Philip K., Tracy, Russell P., Schwartz, Stephen M., Rieder, Mark, Liu, Kiang, Williams, O. Dale, Iribarren, Carlos, Lewis, E. Cora, Fornage, Myriam, Boerwinkle, Eric, Gross, Myron, Jaquish, Cashell, Nickerson, Deborah A., Myers, Richard M., Siscovick, David S., Reiner, Alexander P.

Get full text

Punctuated Evolution of Prostate Cancer Genomes by Baca, Sylvan C., Prandi, Davide, Lawrence, Michael S., Mosquera, Juan Miguel, Romanel, Alessandro, Drier, Yotam, Park, Kyung, Kitabayashi, Naoki, MacDonald, Theresa Y., Ghandi, Mahmoud, Van Allen, Eliezer, Kryukov, Gregory V., Sboner, Andrea, Theurillat, Jean-Philippe, Soong, T. David, Nickerson, Elizabeth, Auclair, Daniel, Tewari, Ashutosh, Beltran, Himisha, Onofrio, Robert C., Boysen, Gunther, Guiducci, Candace, Barbieri, Christopher E., Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L., Saksena, Gordon, Voet, Douglas, Ramos, Alex H., Winckler, Wendy, Cipicchio, Michelle, Ardlie, Kristin, Kantoff, Philip W., Berger, Michael F., Gabriel, Stacey B., Golub, Todd R., Meyerson, Matthew, Lander, Eric S., Elemento, Olivier, Getz, Gad, Demichelis, Francesca, Rubin, Mark A., Garraway, Levi A.

Get full text