A Human Cellular Model for Studying the Regulation of Glucagon-Like Peptide-1 Secretion by Reimer, Raylene A, Darimont, Christian, Gremlich, Sandrine, Nicolas-Métral, Valérie, Rüegg, Urs T, Macé, Katherine

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The effects of CYP3A4 induction and inhibition on the pharmacokinetics of alisporivir in humans by Barve, Avantika, Kovacs, Steven J., Ke, June, Crabbe, Rafael, Grosgurin, Peter, Menetrey, Annick, Nicolas-Métral, Valerie, Dabovic, Kristina, Dole, Kiran, Zhang, Jie, Praestgaard, Jens, Sunkara, Gangadhar, Stein, Daniel

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Model-based translation of results from in vitro to in vivo experiments for afabicin activity against Staphylococcus aureus by Saporta, Raphaël, Nielsen, Elisabet I, Menetrey, Annick, Cameron, David R, Nicolas-Metral, Valérie, Friberg, Lena E

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Bone and Joint Tissue Penetration of the Staphylococcus -Selective Antibiotic Afabicin in Patients Undergoing Elective Hip Replacement Surgery by Menetrey, Annick, Janin, Annick, Pullman, John, Overcash, J Scott, Haouala, Amina, Leylavergne, François, Turbe, Laurent, Wittke, Frederick, Nicolas-Métral, Valérie

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Erythropoietin Stimulates Proliferation and Interferes with Differentiation of Myoblasts by Ogilvie, Martha, Yu, Xiaobing, Nicolas-Metral, Valerie, Pulido, Silvia M., Liu, Chun, Ruegg, Urs T., Noguchi, Constance Tom

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Pharmacological control of cellular calcium handling in dystrophic skeletal muscle by Ruegg, Urs T, Nicolas-Métral, Valérie, Challet, Corinne, Bernard-Hélary, Katy, Dorchies, Olivier M, Wagner, Stéphanie, Buetler, Timo M

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Single-Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of a FabI Inhibitor, the Prodrug Debio 1450 and Its Active Moiety Debio 1452, Administered I... by Hafkin, Barry, Berg, Jolene K, Kaplan, Nachum, Métral, Valérie Nicolas, Ménétrey, Annick, Alcorn, Harry, Wittke, Frederick

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797Single-Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of a FabI Inhibitor, the Prodrug Debio 1450 and Its Active Moiety Debio 1452, Administere... by Hafkin, Barry, Berg, Jolene K, Kaplan, Nachum, Métral, Valérie Nicolas, Ménétrey, Annick, Jr, Harry Alcorn, Wittke, Frederick

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A Phase I, Open-Label, Multicenter, Dose-escalation Study of the Oral Selective FGFR Inhibitor Debio 1347 in Patients with Advanced Solid Tumors Harboring FGFR Gene Alterations by Voss, Martin H, Hierro, Cinta, Heist, Rebecca S, Cleary, James M, Meric-Bernstam, Funda, Tabernero, Josep, Janku, Filip, Gandhi, Leena, Iafrate, A John, Borger, Darrell R, Ishii, Nobuya, Hu, Youyou, Kirpicheva, Yulia, Nicolas-Metral, Valerie, Pokorska-Bocci, Anna, Vaslin Chessex, Anne, Zanna, Claudio, Flaherty, Keith T, Baselga, Jose

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Evaluating Debio 1347 in Patients with FGFR Fusion-Positive Advanced Solid Tumors from the FUZE Multicenter, Open-Label, Phase II Basket Trial by Grivas, Petros, Garralda, Elena, Meric-Bernstam, Funda, Mellinghoff, Ingo K, Goyal, Lipika, Harding, James J, Dees, E Claire, Bahleda, Rastislav, Azad, Nilofer S, Karippot, Asha, Kurzrock, Razelle, Tabernero, Josep, Kononen, Juha, Ng, Matthew C H, Mehta, Rutika, Uboha, Nataliya V, Bigot, Frédéric, Boni, Valentina, Bowyer, Samantha E, Breder, Valeriy, Cervantes, Andrés, Chan, Nancy, Cleary, James M, Dhawan, Mallika, Eefsen, Rikke L, Ewing, James, Graham, Donna M, Guren, Tormod K, Won Kim, Jin, Koynov, Krassimir, Oh, Do-Youn, Redman, Rebecca, Yen, Chia-Jui, Spetzler, David, Roubaudi-Fraschini, Marie-Claude, Nicolas-Metral, Valerie, Ait-Sarkouh, Rafik, Zanna, Claudio, Ennaji, Abdallah, Pokorska-Bocci, Anna, Flaherty, Keith T

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Abstract CT228: Formulation switch and pharmacokinetics/pharmacodynamics of Debio 1347 (CH5183284), a novel FGFR inhibitor, in a first-in-human dose escalation trial in solid tumor... by Nicolas-Metral, Valerie, Vaslin, Anne, Supko, Jeffrey G., Nakai, Kiyohiko, Ishii, Nobuya, Menetrey, Annick, Roubaudi-Fraschini, Marie-Claude, Marfurt, Judith, Chabaud, Sebastien, Layer, Andreas, Purcea, Daniela, Douchain, Jerome, Zanna, Claudio

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Mdx myotubes have normal excitability but show reduced contraction-relaxation dynamics by Nicolas-Metral, V, Raddatz, E, Kucera, P, Ruegg, U T

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