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A Novel Metabotropic Glutamate Receptor 5 Positive Allosteric Modulator Acts at a Unique Site and Confers Stimulus Bias to mGlu5 Signaling
by
Noetzel, M.J.
,
Gregory, K.J.
,
Vinson, P.N.
,
Manka, J.T.
,
Stauffer, S.R.
,
Lindsley, C.W.
,
Niswender, C.M.
,
Xiang, Z.
,
Conn, P.J.
Published in
Molecular pharmacology
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Molecular Pharmacology
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Allosteric Regulation - Drug Effects
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Allosteric Regulation - Physiology
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Animals
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Benzamides - Metabolism
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Benzamides - Pharmacology
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Binding Sites - Drug Effects
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Binding Sites - Physiology
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Cells, Cultured
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Female
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Hek293 Cells
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Humans
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Life Sciences & Biomedicine
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Male
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Pharmacology & Pharmacy
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Phthalimides - Metabolism
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Phthalimides - Pharmacology
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Rats
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Rats, Sprague-Dawley
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Receptor, Metabotropic Glutamate 5
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Receptors, Metabotropic Glutamate - Agonists
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