Identification of hnRNP-A1 as a pharmacodynamic biomarker of type I PRMT inhibition in blood and tumor tissues by Noto, Paul B., Sikorski, Timothy W., Zappacosta, Francesca, Wagner, Craig D., Montes de Oca, Rocio, Szapacs, Matthew E., Annan, Roland S., Liu, Yan, McHugh, Charles F., Mohammad, Helai P., Piccoli, Steven P., Creasy, Caretha L.

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The Medicinal Chemistry of Liver X Receptor (LXR) Modulators by Tice, Colin M, Noto, Paul B, Fan, Kristi Yi, Zhuang, Linghang, Lala, Deepak S, Singh, Suresh B

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Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists by Lotesta, Stephen D., Marcus, Andrew P., Zheng, Yajun, Leftheris, Katerina, Noto, Paul B., Meng, Shi, Kandpal, Geeta, Chen, Guozhou, Zhou, Jing, McKeever, Brian, Bukhtiyarov, Yuri, Zhao, Yi, Lala, Deepak S., Singh, Suresh B., McGeehan, Gerard M.

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Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) β Agonist by Zheng, Yajun, Zhuang, Linghang, Fan, Kristi Yi, Tice, Colin M, Zhao, Wei, Dong, Chengguo, Lotesta, Stephen D, Leftheris, Katerina, Lindblom, Peter R, Liu, Zhijie, Shimada, Jun, Noto, Paul B, Meng, Shi, Hardy, Andrew, Howard, Lamont, Krosky, Paula, Guo, Joan, Lipinski, Kerri, Kandpal, Geeta, Bukhtiyarov, Yuri, Zhao, Yi, Lala, Deepak, Van Orden, Rebecca, Zhou, Jing, Chen, Guozhou, Wu, Zhongren, McKeever, Brian M, McGeehan, Gerard M, Gregg, Richard E, Claremon, David A, Singh, Suresh B

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Regulation of sphingomyelin phosphodiesterase acid-like 3A gene (SMPDL3A) by liver X receptors by Noto, Paul B, Bukhtiyarov, Yuri, Shi, Meng, McKeever, Brian M, McGeehan, Gerard M, Lala, Deepak S

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Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core by Tice, Colin M., Noto, Paul B., Fan, Kristi Yi, Zhao, Wei, Lotesta, Stephen D., Dong, Chengguo, Marcus, Andrew P., Zheng, Ya-Jun, Chen, Guozhou, Wu, Zhongren, Van Orden, Rebecca, Zhou, Jing, Bukhtiyarov, Yuri, Zhao, Yi, Lipinski, Kerri, Howard, Lamont, Guo, Joan, Kandpal, Geeta, Meng, Shi, Hardy, Andrew, Krosky, Paula, Gregg, Richard E., Leftheris, Katerina, McKeever, Brian M., Singh, Suresh B., Lala, Deepak, McGeehan, Gerard M., Zhuang, Linghang, Claremon, David A.

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Phase 1 study of GSK3368715, a type I PRMT inhibitor, in patients with advanced solid tumors by El-Khoueiry, Anthony B., Clarke, James, Neff, Tobias, Crossman, Tim, Ratia, Nirav, Rathi, Chetan, Noto, Paul, Tarkar, Aarti, Garrido-Laguna, Ignacio, Calvo, Emiliano, Rodón, Jordi, Tran, Ben, O’Dwyer, Peter J., Cuker, Adam, Abdul Razak, Albiruni R.

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Abstract 892: Afamitresgene autoleucel (afami-cel; formerly ADP-A2M4) demonstrates durable clinical responses by inducing broad immune engagement with anti-tumor activity by McAlpine, Cheryl, Isabelle, Martin, Broad, Robyn, Naidoo, Revashnee, Liddle, Ashley, Duperret, Elizabeth, Noto, Paul, Wang, Ruoxi, Batrakou, Dzmitry, Middha, Sumit, Evans, Chris

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The potent, selective RORγt blocker, VTP-43742, suppresses Th17 production in vivo and provides greater benefit than IL-17 blockade in the EAE model of autoimmunity (THER3P.968) by Zhao, Yi, Meng, Shi, Noto, Paul, Bukhtiyarov, Yuri, Stadanlick, Jason, Zhuang, Linghang, Dillard, Lawrence, Claremon, David, Gregg, Richard, McGeehan, Gerard, Lala, Deepak

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Epigenetic modulation of estrogen receptor-α by pRb family proteins : A novel mechanism in breast cancer by MACALUSO, Marcella, MONTANARI, Micaela, NOTO, Paul Bart, GREGORIO, Valter, BRONNER, Christian, GIORDANO, Antonio

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Alternative stabilities of a proline‐rich antibacterial peptide in vitro and in vivo by Noto, Paul Bart, Abbadessa, Giovanni, Cassone, Marco, Mateo, George D., Agelan, Alexis, Wade, John D., Szabo, Dora, Kocsis, Bela, Nagy, Karoly, Rozgonyi, Ferenc, Otvos, Laszlo

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Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists by Lotesta, Stephen D., Marcus, Andrew P., Zheng, Yajun, Leftheris, Katerina, Noto, Paul B., Meng, Shi, Kandpal, Geeta, Chen, Guozhou, Zhou, Jing, McKeever, Brian, Bukhtiyarov, Yuri, Zhao, Yi, Lala, Deepak S., Singh, Suresh B., McGeehan, Gerard M.

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VTP-43742 is a potent and selective RORγt blocker that demonstrates oral efficacy in a mouse model of autoimmunity through suppression of IL-17A production (THER7P.945) by McGeehan, Gerard, Bukhtiyarov, Yuri, Zhao, Yi, Meng, Shi, Noto, Paul, Stadanlick, Jason, Kruk, Barbara, Hardy, Andrew, Lipinski, Kerri, Kandpal, Geeta, Algayer, Bethany, Guo, Joan, Guo, Rong, Marcus, Andrew, Lotesta, Stephen, Dong, Chengguo, Fan, Kristi, Jia, Lanqi, Yuan, Jing, Zheng, Yajun, Zhuang, Linghang, Dillard, Lawrence, Claremon, David, Gregg, Richard, Lala, Deepak

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Potassium and magnesium uptake and fertiliser use efficiency by oil palm at contrasting sites in Sumatra, Indonesia by Prabowo, Noto E., Foster, Hugh L., Nelson, Paul N.

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Comparing methods of detecting and segmenting unruptured intracranial aneurysms on TOF-MRAS: The ADAM challenge by Timmins, Kimberley M., van der Schaaf, Irene C., Bennink, Edwin, Ruigrok, Ynte M., An, Xingle, Baumgartner, Michael, Bourdon, Pascal, De Feo, Riccardo, Noto, Tommaso Di, Dubost, Florian, Fava-Sanches, Augusto, Feng, Xue, Giroud, Corentin, Group, Inteneural, Hu, Minghui, Jaeger, Paul F., Kaiponen, Juhana, Klimont, Michał, Li, Yuexiang, Li, Hongwei, Lin, Yi, Loehr, Timo, Ma, Jun, Maier-Hein, Klaus H., Marie, Guillaume, Menze, Bjoern, Richiardi, Jonas, Rjiba, Saifeddine, Shah, Dhaval, Shit, Suprosanna, Tohka, Jussi, Urruty, Thierry, Walińska, Urszula, Yang, Xiaoping, Yang, Yunqiao, Yin, Yin, Velthuis, Birgitta K., Kuijf, Hugo J.

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An unusual association of hadrosaur and therizinosaur tracks within Late Cretaceous rocks of Denali National Park, Alaska by Fiorillo, Anthony R., McCarthy, Paul J., Kobayashi, Yoshitsugu, Tomsich, Carla S., Tykoski, Ronald S., Lee, Yuong-Nam, Tanaka, Tomonori, Noto, Christopher R.

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Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million pa... by Paciorek, Christopher J, Singleton, Rosie K, Ikeda, Nayu, Laxmaiah, Avula, Widyahening, Indah S, Abarca-Gómez, Leandra, Agdeppa, Imelda A, Ahrens, Wolfgang, Al-Raddadi, Rajaa, Auvinen, Juha, Azimi-Nezhad, Mohsen, Benson, Lowell S, Bernabe-Ortiz, Antonio, Bia, Daniel, Bo, Simona, Bugge, Anna, Cameron, Christine, Censi, Laura, Cheraghian, Bahman, Chien, Kuo-Liong, Chiolero, Arnaud, Costanzo, Simona, Crujeiras, Ana B, Cruz, Juan J, Cuschieri, Sarah, De Curtis, Amalia, De Henauw, Stefaan, Diaz, Alejandro, Dorobantu, Maria, Dushpanova, Anar, Eggertsen, Robert, Ferrante, Daniel, Ferrario, Marco M, Frikke-Schmidt, Ruth, Fuchs, Flavio D, Fuchs, Sandra C, Gao, Jingli, Giampaoli, Simona, Gonçalves, Mauer, Graff-Iversen, Sidsel, Guerrero, Ramiro, Gurzkowska, Beata, Halkjær, Jytte, Hambleton, Ian R, Ibrahim Wong, Norazizah, Kazakbaeva, Gyulli M, Kheiri, Bahareh, Kurjata, Pawel, Le Coroller, Gwenaëlle, Lingam, Vijaya, Magliano, Dianna J, Mahasampath, Gowri, McFarlane, Shelly R, Miller, Jody C, Molnár, Dénes, Mondo, Charles K, Mursu, Jaakko, Nabipour, Iraj, Nang, Ei Ei K, Nejatizadeh, Azim, Noorbala, Ahmad Ali, Nsour, Mohannad Al, Oliveira, Isabel O, Palli, Domenico, Pavlyshyn, Halyna, Pilotto, Lorenza, Puhakka, Soile E, Qasrawi, Radwan F, Ramachandra Rao, Sudha, Ramos, Elisabete, Rech, Cassiano Ricardo, Revilla, Luis, Roggenbuck, Ulla, Roy, Joel GR, Safarpour, Ali Reza, Safiri, Saeid, Salanave, Benoit, Salomaa, Veikko, Sathish, Thirunavukkarasu, Sebert, Sylvain, Silva, Diego Augusto Santos, Sparboe-Nilsen, Bente, Stein, Aryeh D, Stessman, Jochanan, Tai, E Shyong, Tan, Eng Joo, Taylor, Julie, Tham, Yih Chung, Trichopoulou, Antonia, Tshepo, Lechaba, Turley, Maria L, Uusitalo, Hannu MT, van den Born, Bert-Jan, Van Schoor, Natasja M, Virtanen, Jyrki K, Voutilainen, Ari, Wei, Wenbin, Wiecek, Andrzej, Zhang, Luxia, Ezzati, Majid

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Postibrutinib outcomes in patients with mantle cell lymphoma by Martin, Peter, Maddocks, Kami, Leonard, John P., Ruan, Jia, Goy, Andre, Wagner-Johnston, Nina, Rule, Simon, Advani, Ranjana, Iberri, David, Phillips, Tycel, Spurgeon, Stephen, Kozin, Eliana, Noto, Katherine, Chen, Zhengming, Jurczak, Wojciech, Auer, Rebecca, Chmielowska, Ewa, Stilgenbauer, Stephan, Bloehdorn, Johannes, Portell, Craig, Williams, Michael E., Dreyling, Martin, Barr, Paul M., Chen-Kiang, Selina, DiLiberto, Maurizio, Furman, Richard R., Blum, Kristie A.

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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Di Cesare, Mariachiara, Danaei, Goodarz, Bilano, Ver, Bovet, Pascal, Mondo, Charles K, Neuhauser, Hannelore K, Sundström, Johan, Smeeth, Liam, Ezzati, Majid, Acosta-Cazares, Benjamin, Agyemang, Charles, Al Raddadi, Rajaa, Al Woyatan, Rihab, Ängquist, Lars, Ariansen, Inger, Banegas, José R, Batieha, Anwar M, Bernabe-Ortiz, Antonio, Blokstra, Anneke, Bobak, Martin, Brajkovich, Imperia, Cardoso, Viviane C, Caserta, Carmelo A, Chamukuttan, Snehalatha, Chen, Shuohua, Chetrit, Angela, Clays, Els, Cooper, Cyrus, Dehghan, Abbas, Dhana, Klodian, Dulskiene, Virginija, Elosua, Roberto, Faeh, David, Farzadfar, Farshad, Franco, Oscar H, Frontera, Guillermo, Furusawa, Takuro, Geleijnse, Johanna M, Gianfagna, Francesco, Grøntved, Anders, Gurzkowska, Beata, Houti, Leila, Hu, Yonghua, Husseini, Abdullatif S, Kafatos, Anthony, Kauhanen, Jussi, Kaur, Prabhdeep, Kemper, Han C G, Khalili, Davood, Khang, Young-Ho, Le, Tuyen D, Lekhraj, Rampal, Luksiene, Dalia, Manios, Yannis, Marrugat, Jaume, Matijasevich, Alicia, Posso, Anselmo J Mc Donald, McFarlane, Shelly R, Menon, Geetha R, Møller, Niels C, Molnár, Dénes, Momenan, Amirabbas, Moreno, Luis A, Mostafa, Aya, Mota, Jorge, Navarrete-Muñoz, Eva Maria, Noto, Davide, Parnell, Winsome R, Peixoto, Sergio Viana, Pelletier, Catherine, Pereira, Alexandre C, Pilotto, Lorenza, Plans-Rubió, Pedro, Porta, Miquel, Riboli, Elio, Rigo, Fernando, Robinson, Sian M, Rubinstein, Adolfo, Salonen, Jukka T, Salvetti, Massimo, Sans, Susana, Saramies, Jouko L, Schargrodsky, Herman, Sibai, Abla M, Slusarczyk, Przemyslaw, So, Hung-Kwan, Solfrizzi, Vincenzo, Song, Yi, Sørensen, Thorkild IA, Tang, Line, Tao, Yong, Topbas, Murat, Trichopoulou, Antonia, Veronesi, Giovanni, Vrdoljak, Ana, Wojtyniak, Bogdan, Wu, Frederick C, Yusoff, Ahmad F, Yusoff, Muhammad Fadhli M, Zheng, Yingffeng

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Disruption of cholinergic neurotransmission exacerbates Aβ-related cognitive impairment in preclinical Alzheimer's disease by Lim, Yen Ying, Maruff, Paul, Schindler, Rachel, Ott, Brian R, Salloway, Stephen, Yoo, Don C, Noto, Richard B, Santos, Cláudia Y, Snyder, Peter J

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