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Identification of hnRNP-A1 as a pharmacodynamic biomarker of type I PRMT inhibition in blood and tumor tissues
by
Noto, Paul B.
,
Sikorski, Timothy W.
,
Zappacosta, Francesca
,
Wagner, Craig D.
,
Montes de Oca, Rocio
,
Szapacs, Matthew E.
,
Annan, Roland S.
,
Liu, Yan
,
McHugh, Charles F.
,
Mohammad, Helai P.
,
Piccoli, Steven P.
,
Creasy, Caretha L.
Published in
Scientific reports
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The Medicinal Chemistry of Liver X Receptor (LXR) Modulators
by
Tice, Colin M
,
Noto, Paul B
,
Fan, Kristi Yi
,
Zhuang, Linghang
,
Lala, Deepak S
,
Singh, Suresh B
Published in
Journal of medicinal chemistry
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Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists
by
Lotesta, Stephen D.
,
Marcus, Andrew P.
,
Zheng, Yajun
,
Leftheris, Katerina
,
Noto, Paul B.
,
Meng, Shi
,
Kandpal, Geeta
,
Chen, Guozhou
,
Zhou, Jing
,
McKeever, Brian
,
Bukhtiyarov, Yuri
,
Zhao, Yi
,
Lala, Deepak S.
,
Singh, Suresh B.
,
McGeehan, Gerard M.
Published in
Bioorganic & medicinal chemistry
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Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) β Agonist
by
Zheng, Yajun
,
Zhuang, Linghang
,
Fan, Kristi Yi
,
Tice, Colin M
,
Zhao, Wei
,
Dong, Chengguo
,
Lotesta, Stephen D
,
Leftheris, Katerina
,
Lindblom, Peter R
,
Liu, Zhijie
,
Shimada, Jun
,
Noto, Paul B
,
Meng, Shi
,
Hardy, Andrew
,
Howard, Lamont
,
Krosky, Paula
,
Guo, Joan
,
Lipinski, Kerri
,
Kandpal, Geeta
,
Bukhtiyarov, Yuri
,
Zhao, Yi
,
Lala, Deepak
,
Van Orden, Rebecca
,
Zhou, Jing
,
Chen, Guozhou
,
Wu, Zhongren
,
McKeever, Brian M
,
McGeehan, Gerard M
,
Gregg, Richard E
,
Claremon, David A
,
Singh, Suresh B
Published in
Journal of medicinal chemistry
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Regulation of sphingomyelin phosphodiesterase acid-like 3A gene (SMPDL3A) by liver X receptors
by
Noto, Paul B
,
Bukhtiyarov, Yuri
,
Shi, Meng
,
McKeever, Brian M
,
McGeehan, Gerard M
,
Lala, Deepak S
Published in
Molecular pharmacology
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Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core
by
Tice, Colin M.
,
Noto, Paul B.
,
Fan, Kristi Yi
,
Zhao, Wei
,
Lotesta, Stephen D.
,
Dong, Chengguo
,
Marcus, Andrew P.
,
Zheng, Ya-Jun
,
Chen, Guozhou
,
Wu, Zhongren
,
Van Orden, Rebecca
,
Zhou, Jing
,
Bukhtiyarov, Yuri
,
Zhao, Yi
,
Lipinski, Kerri
,
Howard, Lamont
,
Guo, Joan
,
Kandpal, Geeta
,
Meng, Shi
,
Hardy, Andrew
,
Krosky, Paula
,
Gregg, Richard E.
,
Leftheris, Katerina
,
McKeever, Brian M.
,
Singh, Suresh B.
,
Lala, Deepak
,
McGeehan, Gerard M.
,
Zhuang, Linghang
,
Claremon, David A.
Published in
Bioorganic & medicinal chemistry letters
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Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists
by
Lotesta, Stephen D.
,
Marcus, Andrew P.
,
Zheng, Yajun
,
Leftheris, Katerina
,
Noto, Paul B.
,
Meng, Shi
,
Kandpal, Geeta
,
Chen, Guozhou
,
Zhou, Jing
,
McKeever, Brian
,
Bukhtiyarov, Yuri
,
Zhao, Yi
,
Lala, Deepak S.
,
Singh, Suresh B.
,
McGeehan, Gerard M.
Published in
Bioorganic & medicinal chemistry
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Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million pa...
by
Paciorek, Christopher J
,
Singleton, Rosie K
,
Ikeda, Nayu
,
Laxmaiah, Avula
,
Widyahening, Indah S
,
Abarca-Gómez, Leandra
,
Agdeppa, Imelda A
,
Ahrens, Wolfgang
,
Al-Raddadi, Rajaa
,
Auvinen, Juha
,
Azimi-Nezhad, Mohsen
,
Benson, Lowell S
,
Bernabe-Ortiz, Antonio
,
Bia, Daniel
,
Bo, Simona
,
Bugge, Anna
,
Cameron, Christine
,
Censi, Laura
,
Cheraghian, Bahman
,
Chien, Kuo-Liong
,
Chiolero, Arnaud
,
Costanzo, Simona
,
Crujeiras, Ana B
,
Cruz, Juan J
,
Cuschieri, Sarah
,
De Curtis, Amalia
,
De Henauw, Stefaan
,
Diaz, Alejandro
,
Dorobantu, Maria
,
Dushpanova, Anar
,
Eggertsen, Robert
,
Ferrante, Daniel
,
Ferrario, Marco M
,
Frikke-Schmidt, Ruth
,
Fuchs, Flavio D
,
Fuchs, Sandra C
,
Gao, Jingli
,
Giampaoli, Simona
,
Gonçalves, Mauer
,
Graff-Iversen, Sidsel
,
Guerrero, Ramiro
,
Gurzkowska, Beata
,
Halkjær, Jytte
,
Hambleton, Ian R
,
Ibrahim Wong, Norazizah
,
Kazakbaeva, Gyulli M
,
Kheiri, Bahareh
,
Kurjata, Pawel
,
Le Coroller, Gwenaëlle
,
Lingam, Vijaya
,
Magliano, Dianna J
,
Mahasampath, Gowri
,
McFarlane, Shelly R
,
Miller, Jody C
,
Molnár, Dénes
,
Mondo, Charles K
,
Mursu, Jaakko
,
Nabipour, Iraj
,
Nang, Ei Ei K
,
Nejatizadeh, Azim
,
Noorbala, Ahmad Ali
,
Nsour, Mohannad Al
,
Oliveira, Isabel O
,
Palli, Domenico
,
Pavlyshyn, Halyna
,
Pilotto, Lorenza
,
Puhakka, Soile E
,
Qasrawi, Radwan F
,
Ramachandra Rao, Sudha
,
Ramos, Elisabete
,
Rech, Cassiano Ricardo
,
Revilla, Luis
,
Roggenbuck, Ulla
,
Roy, Joel GR
,
Safarpour, Ali Reza
,
Safiri, Saeid
,
Salanave, Benoit
,
Salomaa, Veikko
,
Sathish, Thirunavukkarasu
,
Sebert, Sylvain
,
Silva, Diego Augusto Santos
,
Sparboe-Nilsen, Bente
,
Stein, Aryeh D
,
Stessman, Jochanan
,
Tai, E Shyong
,
Tan, Eng Joo
,
Taylor, Julie
,
Tham, Yih Chung
,
Trichopoulou, Antonia
,
Tshepo, Lechaba
,
Turley, Maria L
,
Uusitalo, Hannu MT
,
van den Born, Bert-Jan
,
Van Schoor, Natasja M
,
Virtanen, Jyrki K
,
Voutilainen, Ari
,
Wei, Wenbin
,
Wiecek, Andrzej
,
Zhang, Luxia
,
Ezzati, Majid
Published in
The Lancet (British edition)
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Phase 1 study of GSK3368715, a type I PRMT inhibitor, in patients with advanced solid tumors
by
El-Khoueiry, Anthony B.
,
Clarke, James
,
Neff, Tobias
,
Crossman, Tim
,
Ratia, Nirav
,
Rathi, Chetan
,
Noto, Paul
,
Tarkar, Aarti
,
Garrido-Laguna, Ignacio
,
Calvo, Emiliano
,
Rodón, Jordi
,
Tran, Ben
,
O’Dwyer, Peter J.
,
Cuker, Adam
,
Abdul Razak, Albiruni R.
Published in
British journal of cancer
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Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
by
Di Cesare, Mariachiara
,
Danaei, Goodarz
,
Bilano, Ver
,
Bovet, Pascal
,
Mondo, Charles K
,
Neuhauser, Hannelore K
,
Sundström, Johan
,
Smeeth, Liam
,
Ezzati, Majid
,
Acosta-Cazares, Benjamin
,
Agyemang, Charles
,
Al Raddadi, Rajaa
,
Al Woyatan, Rihab
,
Ängquist, Lars
,
Ariansen, Inger
,
Banegas, José R
,
Batieha, Anwar M
,
Bernabe-Ortiz, Antonio
,
Blokstra, Anneke
,
Bobak, Martin
,
Brajkovich, Imperia
,
Cardoso, Viviane C
,
Caserta, Carmelo A
,
Chamukuttan, Snehalatha
,
Chen, Shuohua
,
Chetrit, Angela
,
Clays, Els
,
Cooper, Cyrus
,
Dehghan, Abbas
,
Dhana, Klodian
,
Dulskiene, Virginija
,
Elosua, Roberto
,
Faeh, David
,
Farzadfar, Farshad
,
Franco, Oscar H
,
Frontera, Guillermo
,
Furusawa, Takuro
,
Geleijnse, Johanna M
,
Gianfagna, Francesco
,
Grøntved, Anders
,
Gurzkowska, Beata
,
Houti, Leila
,
Hu, Yonghua
,
Husseini, Abdullatif S
,
Kafatos, Anthony
,
Kauhanen, Jussi
,
Kaur, Prabhdeep
,
Kemper, Han C G
,
Khalili, Davood
,
Khang, Young-Ho
,
Le, Tuyen D
,
Lekhraj, Rampal
,
Luksiene, Dalia
,
Manios, Yannis
,
Marrugat, Jaume
,
Matijasevich, Alicia
,
Posso, Anselmo J Mc Donald
,
McFarlane, Shelly R
,
Menon, Geetha R
,
Møller, Niels C
,
Molnár, Dénes
,
Momenan, Amirabbas
,
Moreno, Luis A
,
Mostafa, Aya
,
Mota, Jorge
,
Navarrete-Muñoz, Eva Maria
,
Noto, Davide
,
Parnell, Winsome R
,
Peixoto, Sergio Viana
,
Pelletier, Catherine
,
Pereira, Alexandre C
,
Pilotto, Lorenza
,
Plans-Rubió, Pedro
,
Porta, Miquel
,
Riboli, Elio
,
Rigo, Fernando
,
Robinson, Sian M
,
Rubinstein, Adolfo
,
Salonen, Jukka T
,
Salvetti, Massimo
,
Sans, Susana
,
Saramies, Jouko L
,
Schargrodsky, Herman
,
Sibai, Abla M
,
Slusarczyk, Przemyslaw
,
So, Hung-Kwan
,
Solfrizzi, Vincenzo
,
Song, Yi
,
Sørensen, Thorkild IA
,
Tang, Line
,
Tao, Yong
,
Topbas, Murat
,
Trichopoulou, Antonia
,
Veronesi, Giovanni
,
Vrdoljak, Ana
,
Wojtyniak, Bogdan
,
Wu, Frederick C
,
Yusoff, Ahmad F
,
Yusoff, Muhammad Fadhli M
,
Zheng, Yingffeng
Published in
The Lancet (British edition)
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Disruption of cholinergic neurotransmission exacerbates Aβ-related cognitive impairment in preclinical Alzheimer's disease
by
Lim, Yen Ying
,
Maruff, Paul
,
Schindler, Rachel
,
Ott, Brian R
,
Salloway, Stephen
,
Yoo, Don C
,
Noto, Richard B
,
Santos, Cláudia Y
,
Snyder, Peter J
Published in
Neurobiology of aging
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Disruption of cholinergic neurotransmission, within a cognitive challenge paradigm, is indicative of Aβ-related cognitive impairment in preclinical Alzheimer's disease after a 27-m...
by
Alber, Jessica
,
Maruff, Paul
,
Santos, Cláudia Y
,
Ott, Brian R
,
Salloway, Stephen P
,
Yoo, Don C
,
Noto, Richard B
,
Thompson, Louisa I
,
Goldfarb, Danielle
,
Arthur, Edmund
,
Song, Alex
,
Snyder, Peter J
Published in
Alzheimer's research & therapy
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Disruption of cholinergic neurotransmission, within a cognitive challenge paradigm, is indicative of A[beta]-related cognitive impairment in preclinical Alzheimer's disease after a...
by
Alber, Jessica
,
Maruff, Paul
,
Santos, Cláudia Y
,
Ott, Brian R
,
Salloway, Stephen P
,
Yoo, Don C
,
Noto, Richard B
,
Thompson, Louisa I
,
Goldfarb, Danielle
,
Arthur, Edmund
,
Song, Alex
,
Snyder, Peter J
Published in
Alzheimer's research & therapy
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Single Photon Emission Computed Tomography, Magnetic Resonance Imaging Hyperintensity, and Cognitive Impairments in Patients With Vascular Dementia
by
Cohen, Ronald A.
,
Paul, Robert H.
,
Zawacki, Tricia M.
,
Sethi, Manish
,
Ott, Brian R.
,
Moser, David J.
,
Stone, William
,
Noto, Richard
,
Gordon, Norman
Published in
Journal of neuroimaging
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