Kilogram-Scale GMP Manufacture of Tirzepatide Using a Hybrid SPPS/LPPS Approach with Continuous Manufacturing by Frederick, Michael O, Boyse, Raymond A, Braden, Timothy M, Calvin, Joel R, Campbell, Bradley M, Changi, Shujauddin M, Coffin, Stephanie R, Condon, Carmel, Gowran, Olivia, McClary Groh, Jennifer, Groskreutz, Stephen R, Harms, Zachary D, Humenik, Ashley A, Kallman, Neil J, Klitzing, Nicholas D, Kopach, Michael E, Kretsinger, Juliana K, Lambertus, Gordon R, Lampert, Jeffrey T, Maguire, Laura M, Moynihan, Humphrey A, Mullane, Nessa S, Murphy, John D, O’Mahony, Marie E, Richey, Rachel N, Seibert, Kevin D, Spencer, Richard D, Strege, Mark A, Tandogan, Nil, Torres Torres, Frank L, Tsukanov, Sergey V, Xia, Han

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Optimizing Therapy to Prevent Avoidable Hospital Admissions in Multimorbid Older Adults (OPERAM): cluster randomised controlled trial by Blum, Manuel R, Sallevelt, Bastiaan T G M, Spinewine, Anne, O’Mahony, Denis, Moutzouri, Elisavet, Feller, Martin, Baumgartner, Christine, Roumet, Marie, Jungo, Katharina Tabea, Schwab, Nathalie, Bretagne, Lisa, Beglinger, Shanthi, Aubert, Carole E, Wilting, Ingeborg, Thevelin, Stefanie, Murphy, Kevin, Huibers, Corlina J A, Drenth-van Maanen, A Clara, Boland, Benoit, Crowley, Erin, Eichenberger, Anne, Meulendijk, Michiel, Jennings, Emma, Adam, Luise, Roos, Marvin J, Gleeson, Laura, Shen, Zhengru, Marien, Sophie, Meinders, Arend-Jan, Baretella, Oliver, Netzer, Seraina, de Montmollin, Maria, Fournier, Anne, Mouzon, Ariane, O’Mahony, Cian, Aujesky, Drahomir, Mavridis, Dimitris, Byrne, Stephen, Jansen, Paul A F, Schwenkglenks, Matthias, Spruit, Marco, Dalleur, Olivia, Knol, Wilma, Trelle, Sven, Rodondi, Nicolas

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Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies by Kennedy, Katherine M., de Goffau, Marcus C., Perez-Muñoz, Maria Elisa, Arrieta, Marie-Claire, Bäckhed, Fredrik, Bork, Peer, Braun, Thorsten, Bushman, Frederic D., Dore, Joel, de Vos, Willem M., Earl, Ashlee M., Eisen, Jonathan A., Elovitz, Michal A., Ganal-Vonarburg, Stephanie C., Gänzle, Michael G., Garrett, Wendy S., Hall, Lindsay J., Hornef, Mathias W., Huttenhower, Curtis, Konnikova, Liza, Lebeer, Sarah, Macpherson, Andrew J., Massey, Ruth C., McHardy, Alice Carolyn, Koren, Omry, Lawley, Trevor D., Ley, Ruth E., O’Mahony, Liam, O’Toole, Paul W., Pamer, Eric G., Parkhill, Julian, Raes, Jeroen, Rattei, Thomas, Salonen, Anne, Segal, Eran, Segata, Nicola, Shanahan, Fergus, Sloboda, Deborah M., Smith, Gordon C. S., Sokol, Harry, Spector, Tim D., Surette, Michael G., Tannock, Gerald W., Walker, Alan W., Yassour, Moran, Walter, Jens

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Trends in congenital anomalies in Europe from 1980 to 2012 by Morris, Joan K, Springett, Anna L, Greenlees, Ruth, Loane, Maria, Addor, Marie-Claude, Arriola, Larraitz, Barisic, Ingeborg, Bergman, Jorieke E H, Csaky-Szunyogh, Melinda, Dias, Carlos, Draper, Elizabeth S, Garne, Ester, Gatt, Miriam, Khoshnood, Babak, Klungsoyr, Kari, Lynch, Catherine, McDonnell, Robert, Nelen, Vera, Neville, Amanda J, O'Mahony, Mary, Pierini, Anna, Queisser-Luft, Annette, Randrianaivo, Hanitra, Rankin, Judith, Rissmann, Anke, Kurinczuk, Jennifer, Tucker, David, Verellen-Dumoulin, Christine, Wellesley, Diana, Dolk, Helen

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The use of hydrophobic amino acids in protecting spray dried trehalose formulations against moisture-induced changes by Mah, Pei T., O'Connell, Peter, Focaroli, Stefano, Lundy, Ross, O'Mahony, Tom F., Hastedt, Jayne E., Gitlin, Irina, Oscarson, Stefan, Fahy, John V., Healy, Anne Marie

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Report of the Lancet Commission on the Value of Death: bringing death back into life by Sallnow, Libby, Smith, Richard, Ahmedzai, Sam H, Bhadelia, Afsan, Chamberlain, Charlotte, Cong, Yali, Doble, Brett, Dullie, Luckson, Durie, Robin, Finkelstein, Eric A, Guglani, Sam, Hodson, Melanie, Husebø, Bettina S, Kellehear, Allan, Kitzinger, Celia, Knaul, Felicia Marie, Murray, Scott A, Neuberger, Julia, O'Mahony, Seamus, Rajagopal, M R, Russell, Sarah, Sase, Eriko, Sleeman, Katherine E, Solomon, Sheldon, Taylor, Ros, Tutu van Furth, Mpho, Wyatt, Katrina

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The Combined Interpretation of 68Ga-DOTATATE PET/CT and 18F-FDG PET/CT in Metastatic Gastroenteropancreatic Neuroendocrine Tumors: A Classification System With Prognostic Impact by Hayes, Aimee R., Furtado O'Mahony, Luke, Quigley, Ann-Marie, Gnanasegaran, Gopinath, Caplin, Martyn E., Navalkissoor, Shaunak, Toumpanakis, Christos

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Clinical, environmental, and genetic determinants of multiple sclerosis in children with acute demyelination: a prospective national cohort study by Banwell, Brenda, Dr, Bar-Or, Amit, MD, Arnold, Douglas L, Prof, Sadovnick, Dessa, Prof, Narayanan, Sridar, PhD, McGowan, Melissa, MSc, O'Mahony, Julia, MSc, Magalhaes, Sandra, MSc, Hanwell, Heather, MSc, Vieth, Reinhold, Prof, Tellier, Raymond, MD, Vincent, Thierry, PhD, Disanto, Giulio, MD, Ebers, George, Prof, Wambera, Katherine, MD, Connolly, Mary B, MBBCh, Yager, Jerome, Prof, Mah, Jean K, MD, Booth, Fran, MD, Sebire, Guillaume, MD, Callen, David, MD, Meaney, Brandon, MD, Dilenge, Marie-Emmanuelle, MD, Lortie, Anne, MD, Pohl, Daniela, MD, Doja, Asif, MD, Venketaswaran, Sunita, MD, Levin, Simon, MD, MacDonald, E Athen, MD, Meek, David, MD, Wood, Ellen, MD, Lowry, Noel, MD, Buckley, David, MD, Yim, Conrad, MD, Awuku, Mark, MD, Cooper, Pamela, MD, Grand'Maison, François, MD, Baird, J Burke, MD, Bhan, Virender, MD, Marrie, Ruth Ann, MD

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Epidemiology of congenital cerebral anomalies in Europe: a multicentre, population-based EUROCAT study by Morris, Joan K, Wellesley, Diana G, Barisic, Ingeborg, Addor, Marie-Claude, Bergman, Jorieke E H, Braz, Paula, Cavero-Carbonell, Clara, Draper, Elizabeth S, Gatt, Miriam, Haeusler, Martin, Klungsoyr, Kari, Kurinczuk, Jennifer J, Lelong, Natalie, Luyt, Karen, Lynch, Catherine, O’Mahony, Mary T, Mokoroa, Olatz, Nelen, Vera, Neville, Amanda J, Pierini, Anna, Randrianaivo, Hanitra, Rankin, Judith, Rissmann, Anke, Rouget, Florence, Schaub, Bruno, Tucker, David F, Verellen-Dumoulin, Christine, Wiesel, Awi, Zymak-Zakutnia, Natalia, Lanzoni, Monica, Garne, Ester

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Epidemiology of Pierre‐Robin sequence in Europe: A population‐based EUROCAT study by Santoro, Michele, Coi, Alessio, Barišić, Ingeborg, Pierini, Anna, Addor, Marie‐Claude, Baldacci, Silvia, Ballardini, Elisa, Boban, Ljubica, Braz, Paula, Cavero‐Carbonell, Clara, Walle, Hermien E. K., Draper, Elizabeth S., Gatt, Miriam, Haeusler, Martin, Klungsøyr, Kari, Kurinczuk, Jennifer J., Materna‐Kiryluk, Anna, Lanzoni, Monica, Lelong, Nathalie, Luyt, Karen, Mokoroa, Olatz, Mullaney, Carmel, Nelen, Vera, O’Mahony, Mary T., Perthus, Isabelle, Randrianaivo, Hanitra, Rankin, Judith, Rissmann, Anke, Rouget, Florence, Schaub, Bruno, Tucker, David, Wellesley, Diana, Zymak‐Zakutnia, Nataliia, Garne, Ester

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Epidemiology of aplasia cutis congenita: A population‐based study in Europe by Coi, Alessio, Barisic, Ingeborg, Garne, Ester, Pierini, Anna, Addor, Marie‐Claude, Aizpurua Atxega, Amaia, Ballardini, Elisa, Braz, Paula, Broughan, Jennifer M., Cavero‐Carbonell, Clara, Walle, Hermien E. K., Draper, Elizabeth S., Gatt, Miriam, Häusler, Martin, Kinsner‐Ovaskainen, Agnieszka, Kurinczuk, Jennifer J., Lelong, Nathalie, Luyt, Karen, Mezzasalma, Lorena, Mullaney, Carmel, Nelen, Vera, Odak, Ljubica, O'Mahony, Mary T., Perthus, Isabelle, Randrianaivo, Hanitra, Rankin, Judith, Rissmann, Anke, Rouget, Florence, Schaub, Bruno, Tucker, David, Wellesley, Diana, Wiśniewska, Katarzyna, Yevtushok, Lyubov, Santoro, Michele

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Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2 by O’Mahony, Denise G., Ramus, Susan J., Southey, Melissa C., Meagher, Nicola S., Hadjisavvas, Andreas, John, Esther M., Hamann, Ute, Imyanitov, Evgeny N., Andrulis, Irene L., Sharma, Priyanka, Daly, Mary B., Hake, Christopher R., Weitzel, Jeffrey N., Jakubowska, Anna, Godwin, Andrew K., Arason, Adalgeir, Bane, Anita, Simard, Jacques, Soucy, Penny, Caligo, Maria A., Mai, Phuong L., Claes, Kathleen B. M., Teixeira, Manuel R., Chung, Wendy K., Lazaro, Conxi, Hulick, Peter J., Toland, Amanda E., Pedersen, Inge Sokilde, Neuhausen, Susan L., Vega, Ana, de la Hoya, Miguel, Nevanlinna, Heli, Dhawan, Mallika, Zampiga, Valentina, Danesi, Rita, Varesco, Liliana, Gismondi, Viviana, Vellone, Valerio Gaetano, James, Paul A., Janavicius, Ramunas, Nikitina-Zake, Liene, Nielsen, Finn Cilius, van Overeem Hansen, Thomas, Pejovic, Tanja, Borg, Ake, Rantala, Johanna, Offit, Kenneth, Montagna, Marco, Nathanson, Katherine L., Domchek, Susan M., Osorio, Ana, García, María J., Karlan, Beth Y., De Fazio, Anna, Bowtell, David, McGuffog, Lesley, Leslie, Goska, Parsons, Michael T., Dörk, Thilo, Speith, Lisa-Marie, dos Santos, Elizabeth Santana, da Costa, Alexandre André B. A., Radice, Paolo, Peterlongo, Paolo, Papi, Laura, Engel, Christoph, Hahnen, Eric, Schmutzler, Rita K., Wappenschmidt, Barbara, Easton, Douglas F., Tischkowitz, Marc, Singer, Christian F., Tan, Yen Yen, Whittemore, Alice S., Sieh, Weiva, Brenton, James D., Yannoukakos, Drakoulis, Fostira, Florentia, Konstantopoulou, Irene, Soukupova, Jana, Vocka, Michal, Chenevix-Trench, Georgia, Pharoah, Paul D. P., Antoniou, Antonis C., Goldgar, David E., Spurdle, Amanda B., Michailidou, Kyriaki

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Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies by Ambler, Gareth, Lee, Keon-Joo, Shiozawa, Masayuki, Lovelock, Caroline, Hennerici, Michael, Lam, Bonnie Yin Ka, Gattringer, Thomas, Uysal, Ender, Bornstein, Natan M, Assayag, Einor Ben, Hara, Hideo, Seiffge, David J, Al-Shahi Salman, Rustam, Lip, Gregory Y H, Mas, Jean-Louis, Legrand, Laurence, Karayiannis, Christopher, Abrigo, Jill, Leung, Thomas, Chu, Winnie, Hayden, Derek, Williams, David J, Barbato, Carmen, Browning, Simone, Maaijwee, Noortje, Delmaire, Christine, van Oostenbrugge, Robert, Lou, Min, Kandiah, Nagaendran, de Leeuw, Frank-Erik, Fluri, Felix, Srikanth, Velandai, Jung, Simon, Heo, Ji Hoe, Veltkamp, Roland, Ay, Hakan, Lau, Kui Kai, Jouvent, Eric, Rothwell, Peter M, Bae, Hee-Joon, Werring, David J, Sword, Jane, Kelly, Deborah, Smith, Matthew, Elmarim, Abduelbaset, Esisi, Bernard, Hassan, Ahamad, Cohen, David, Proschel, Harald, Burn, Mathew, Marsh, Rachel, Prabhakaran, Mathuri, Sprigg, Nikola, Manawadu, Dulka, England, Timothy, Power, Michael, Dani, Krishna, Mangion, David, Corrigan, John, Brown, Martin, Charidimou, Andreas, Banerjee, Gargi, El-Koussy, Marwan, Maeder, Philippe, Gass, Achim, Vicaut, Eric, Sato, Shoichiro, Miwa, Kaori, Ly, John, Singhal, Shahoo, Thilemann, Sebastian, Fladt, Joachim, Han, Moon-Ku, Kang, Jihoon, Murphy, Sean, Carty, Fiona, Schembri, Mark, Marín, Rebeca, Camps-Renom, Pol, Guisado-Alonso, Daniel, Nuñez, Fidel, Ikeda, Syuhei, Zerna, Charlotte, Armitage, Paul, Thrippleton, Michael, Dennis, Martin, Kwan, Joseph Shiu Kwong, Chang, Richard, Chan, Chung Yan, Wong, Edmund Ka Ming, Leung, Kam Tat, Ramos, Lino, De Schryver, Els, Jöbsis, Joost, van der Sande, Jaap, Brouwers, Paul, Schoonewille, Wouter, Linn, Cisca, Mess, Werner, Ward, Nicholas

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Project Respect: LGBTQ+ Experiences with Healthcare Providers for Serious Illness (SA317A) by Stein, Gary L., Berkman, Cathy, O'Mahony, Sean, Godfrey, David, Javier, Noelle Marie, Maingi, Shail, Rosa, William E., Acquaviva, Kimberly D.

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High rates of health care utilization in pediatric multiple sclerosis: A Canadian population-based study by Marrie, Ruth Ann, O'Mahony, Julia, Maxwell, Colleen J, Ling, Vicki, Yeh, E Ann, Arnold, Douglas L, Bar-Or, Amit, Banwell, Brenda

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Microneedle array design determines the induction of protective memory CD8+ T cell responses induced by a recombinant live malaria vaccine in mice by Carey, John B, Pearson, Frances E, Vrdoljak, Anto, McGrath, Marie G, Crean, Abina M, Walsh, Patrick T, Doody, Timothy, O'Mahony, Conor, Hill, Adrian V S, Moore, Anne C

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Prevalence of microcephaly in Europe: population based study by Morris, Joan K, Rankin, Judith, Garne, Ester, Loane, Maria, Greenlees, Ruth, Addor, Marie-Claude, Arriola, Larraitz, Barisic, Ingeborg, Bergman, Jorieke E H, Csaky-Szunyogh, Melinda, Dias, Carlos, Draper, Elizabeth S, Gatt, Miriam, Khoshnood, Babak, Klungsoyr, Kari, Kurinczuk, Jennifer J, Lynch, Catherine, McDonnell, Robert, Nelen, Vera, Neville, Amanda J, O’Mahony, Mary T, Pierini, Anna, Randrianaivo, Hanitra, Rissmann, Anke, Tucker, David, Verellen-Dumoulin, Christine, de Walle, Hermien E K, Wellesley, Diana, Wiesel, Awi, Dolk, Helen

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Prevention of Neural Tube Defects in Europe: A Public Health Failure by Morris, Joan K., Addor, Marie-Claude, Ballardini, Elisa, Barisic, Ingeborg, Barrachina-Bonet, Laia, Braz, Paula, Cavero-Carbonell, Clara, Den Hond, Elly, Garne, Ester, Gatt, Miriam, Haeusler, Martin, Khoshnood, Babak, Lelong, Nathalie, Kinsner-Ovaskainen, Agnieszka, Kiuru-Kuhlefelt, Sonja, Klungsoyr, Kari, Latos-Bielenska, Anna, Limb, Elizabeth, O'Mahony, Mary T, Perthus, Isabelle, Pierini, Anna, Rankin, Judith, Rissmann, Anke, Rouget, Florence, Sayers, Gerardine, Sipek, Antonin, Stevens, Sarah, Tucker, David, Verellen-Dumoulin, Christine, de Walle, Hermien E. K., Wellesley, Diana, Wertelecki, Wladimir, Bermejo-Sanchez, Eva

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Epidemiology of achondroplasia: A population‐based study in Europe by Coi, Alessio, Santoro, Michele, Garne, Ester, Pierini, Anna, Addor, Marie‐Claude, Alessandri, Jean‐Luc, Bergman, Jorieke E. H., Bianchi, Fabrizio, Boban, Ljubica, Braz, Paula, Cavero‐Carbonell, Clara, Gatt, Miriam, Haeusler, Martin, Klungsøyr, Kari, Kurinczuk, Jennifer J., Lanzoni, Monica, Lelong, Nathalie, Luyt, Karen, Mokoroa, Olatz, Mullaney, Carmel, Nelen, Vera, Neville, Amanda J., O'Mahony, Mary T., Perthus, Isabelle, Rankin, Judith, Rissmann, Anke, Rouget, Florence, Schaub, Bruno, Tucker, David, Wellesley, Diana, Wisniewska, Katarzyna, Zymak‐Zakutnia, Nataliia, Barišić, Ingeborg

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Abnormal effector and regulatory T cell subsets in paediatric-onset multiple sclerosis by Mexhitaj, Ina, Nyirenda, Mukanthu H, Li, Rui, O'Mahony, Julia, Rezk, Ayman, Rozenberg, Ayal, Moore, Craig S, Johnson, Trina, Sadovnick, Dessa, Collins, D Louis, Arnold, Douglas L, Gran, Bruno, Yeh, E Ann, Marrie, Ruth Ann, Banwell, Brenda, Bar-Or, Amit

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