Search Results - Offman, Marc N.

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  1. 1
    A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease

    A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease by Zimprich, Alexander, Benet-Pagès, Anna, Struhal, Walter, Graf, Elisabeth, Eck, Sebastian H., Offman, Marc N., Haubenberger, Dietrich, Spielberger, Sabine, Schulte, Eva C., Lichtner, Peter, Rossle, Shaila C., Klopp, Norman, Wolf, Elisabeth, Seppi, Klaus, Pirker, Walter, Presslauer, Stefan, Mollenhauer, Brit, Katzenschlager, Regina, Foki, Thomas, Hotzy, Christoph, Reinthaler, Eva, Harutyunyan, Ashot, Kralovics, Robert, Peters, Annette, Zimprich, Fritz, Brücke, Thomas, Poewe, Werner, Auff, Eduard, Trenkwalder, Claudia, Rost, Burkhard, Ransmayr, Gerhard, Winkelmann, Juliane, Meitinger, Thomas, Strom, Tim M.

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  2. 2
    Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell toxicity

    Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell toxicity by Offman, Marc N., Krol, Marcin, Patel, Naina, Krishnan, Shekhar, Liu, JiZhong, Saha, Vaskar, Bates, Paul A.

    Published in Blood
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  3. 3
    Molecular Basis of Reduced Glucosylceramidase Activity in the Most Common Gaucher Disease Mutant, N370S

    Molecular Basis of Reduced Glucosylceramidase Activity in the Most Common Gaucher Disease Mutant, N370S by Offman, Marc N., Krol, Marcin, Silman, Israel, Sussman, Joel L., Futerman, Anthony H.

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  4. 4
    A dyad of lymphoblastic lysosomal cysteine proteases degrades the antileukemic drug L-asparaginase

    A dyad of lymphoblastic lysosomal cysteine proteases degrades the antileukemic drug L-asparaginase by Patel, Naina, Krishnan, Shekhar, Offman, Marc N, Krol, Marcin, Moss, Catherine X, Leighton, Carly, van Delft, Frederik W, Holland, Mark, Liu, Jizhong, Alexander, Seema, Dempsey, Clare, Ariffin, Hany, Essink, Monika, Eden, Tim O B, Watts, Colin, Bates, Paul A, Saha, Vaskar

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  5. 5
    Comparison of a molecular dynamics model with the X-ray structure of the N370S acid-β-glucosidase mutant that causes Gaucher disease

    Comparison of a molecular dynamics model with the X-ray structure of the N370S acid-β-glucosidase mutant that causes Gaucher disease by Offman, Marc N., Krol, Marcin, Rost, Burkhard, Silman, Israel, Sussman, Joel L., Futerman, Anthony H.

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  6. 6
    Comparison of a molecular dynamics model with the X-ray structure of the N370S acid- -glucosidase mutant that causes Gaucher disease

    Comparison of a molecular dynamics model with the X-ray structure of the N370S acid- -glucosidase mutant that causes Gaucher disease by Offman, M. N., Krol, M., Rost, B., Silman, I., Sussman, J. L., Futerman, A. H.

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  7. 7
    Developing a move-set for protein model refinement

    Developing a move-set for protein model refinement by Offman, Marc N., Fitzjohn, Paul W., Bates, Paul A.

    Published in Bioinformatics
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  8. 8
    Alternating evolutionary pressure in a genetic algorithm facilitates protein model selection

    Alternating evolutionary pressure in a genetic algorithm facilitates protein model selection by Offman, Marc N, Tournier, Alexander L, Bates, Paul A

    Published in BMC structural biology
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  9. 9
    No statistical support for correlation between the positions of protein interaction sites and alternatively spliced regions

    No statistical support for correlation between the positions of protein interaction sites and alternatively spliced regions by Offman, Marc N, Nurtdinov, Ramil N, Gelfand, Mikhail S, Frishman, Dmitrij

    Published in BMC bioinformatics
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  10. 10
    Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell tonicity

    Rational engineering of L-asparaginase reveals importance of dual activity for cancer cell tonicity by OFFMAN, Marc N, KROL, Marcin, PATEL, Naina, KRISHNAN, Shekhar, JIZHONG LIU, SAHA, Vaskar, BATES, Paul A

    Published in Blood
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  11. 11
    Lymphoblasts Produce a Lysosomal Protease That Rapidly Degrades L-Asparaginase - Implications for Therapy in Childhood Acute Lymphoblastic Leukemia

    Lymphoblasts Produce a Lysosomal Protease That Rapidly Degrades L-Asparaginase - Implications for Therapy in Childhood Acute Lymphoblastic Leukemia by Patel, Naina, Krishnan, Shekhar, Offman, Marc N., Moss, Cathy X., Ariffin, Hany, vanDelft, Fred W., Yiannikouris, Olga, Leighton, Carly, Alexander, Seema, Holland, Mark, Khater, Doaa, Liu, Ji Zhong, Essink, Monika, Bates, Paul, Watts, Colin, Saha, Vaskar

    Published in Blood
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