LP-18: Challenges and Opportunities in Use of the Minipig for Nonclinical Pharmaceutical Development: Results of the Second IQ DruSafe Minipig Survey by Harding, J., Datta, K., Olaharski, D., Clarke, D., Flandre, T., French, K., Leach, M., Mohr, S., Strein, D., Gauthier, B.

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Non-clinical identification and characterization of KRAS G12D inhibitors by Brooun, A., Bae, J.H., Chen, H., Li, P., Lin, B., Fagan, P., Irimia, A., Nevarez, R., Zhang, J., Chen, P., Olaharski, D., Chiang, G., Vernier, J.M., Shoemaker, R.

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Tetraploidy and chromosomal instability are early events during cervical carcinogenesis by Olaharski, Andrew J., Sotelo, Rita, Solorza-Luna, Gilberto, Gonsebatt, Maria E., Guzman, Patricia, Mohar, Alejandro, Eastmond, David A.

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Discovery of AG-120 (Ivosidenib): A First-in-Class Mutant IDH1 Inhibitor for the Treatment of IDH1 Mutant Cancers by Popovici-Muller, Janeta, Lemieux, René M, Artin, Erin, Saunders, Jeffrey O, Salituro, Francesco G, Travins, Jeremy, Cianchetta, Giovanni, Cai, Zhenwei, Zhou, Ding, Cui, Dawei, Chen, Ping, Straley, Kimberly, Tobin, Erica, Wang, Fang, David, Muriel D, Penard-Lacronique, Virginie, Quivoron, Cyril, Saada, Véronique, de Botton, Stéphane, Gross, Stefan, Dang, Lenny, Yang, Hua, Utley, Luke, Chen, Yue, Kim, Hyeryun, Jin, Shengfang, Gu, Zhiwei, Yao, Gui, Luo, Zhiyong, Lv, Xiaobing, Fang, Cheng, Yan, Liping, Olaharski, Andrew, Silverman, Lee, Biller, Scott, Su, Shin-San M, Yen, Katharine

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Chromosomal malsegregation and micronucleus induction in vitro by the DNA topoisomerase II inhibitor fisetin by Olaharski, A.J., Mondrala, S.T., Eastmond, D.A.

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Interlaboratory Evaluation of Genomic Signatures for Predicting Carcinogenicity in the Rat by Fielden, Mark R., Nie, Alex, McMillian, Michael, Elangbam, Chandi S., Trela, Bruce A., Yang, Yi, Dunn, Robert T., Dragan, Yvonne, Fransson-Stehen, Ronny, Bogdanffy, Matthew, Adams, Stephen P., Foster, William R., Chen, Shen-Jue, Rossi, Phil, Kasper, Peter, Jacobson-Kram, David, Tatsuoka, Kay S., Wier, Patrick J., Gollub, Jeremy, Halbert, Donald N., Roter, Alan, Young, Jamie K., Sina, Joseph F., Marlowe, Jennifer, Martus, Hans-Joerg, Aubrecht, Jiri, Olaharski, Andrew J., Roome, Nigel, Nioi, Paul, Pardo, Ingrid, Snyder, Ron, Perry, Richard, Lord, Peter, Mattes, William, Car, Bruce D.

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Elevated levels of tetraploid cervical cells in human papillomavirus‐positive Papanicolaou smears diagnosed as atypical squamous cells of undetermined significance by Olaharski, Andrew J., Eastmond, David A.

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