AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer by Cross, Darren A E, Ashton, Susan E, Ghiorghiu, Serban, Eberlein, Cath, Nebhan, Caroline A, Spitzler, Paula J, Orme, Jonathon P, Finlay, M Raymond V, Ward, Richard A, Mellor, Martine J, Hughes, Gareth, Rahi, Amar, Jacobs, Vivien N, Red Brewer, Monica, Ichihara, Eiki, Sun, Jing, Jin, Hailing, Ballard, Peter, Al-Kadhimi, Katherine, Rowlinson, Rachel, Klinowska, Teresa, Richmond, Graham H P, Cantarini, Mireille, Kim, Dong-Wan, Ranson, Malcolm R, Pao, William

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Structure- and Reactivity-Based Development of Covalent Inhibitors of the Activating and Gatekeeper Mutant Forms of the Epidermal Growth Factor Receptor (EGFR) by Ward, Richard A, Anderton, Mark J, Ashton, Susan, Bethel, Paul A, Box, Matthew, Butterworth, Sam, Colclough, Nicola, Chorley, Christopher G, Chuaqui, Claudio, Cross, Darren A. E, Dakin, Les A, Debreczeni, Judit É, Eberlein, Cath, Finlay, M. Raymond V, Hill, George B, Grist, Matthew, Klinowska, Teresa C. M, Lane, Clare, Martin, Scott, Orme, Jonathon P, Smith, Peter, Wang, Fengjiang, Waring, Michael J

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Protein–Ligand Crystal Structures Can Guide the Design of Selective Inhibitors of the FGFR Tyrosine Kinase by Norman, Richard A, Schott, Anne-Kathrin, Andrews, David M, Breed, Jason, Foote, Kevin M, Garner, Andrew P, Ogg, Derek, Orme, Jonathon P, Pink, Jennifer H, Roberts, Karen, Rudge, David A, Thomas, Andrew P, Leach, Andrew G

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Discovery of a Potent and Selective EGFR Inhibitor (AZD9291) of Both Sensitizing and T790M Resistance Mutations That Spares the Wild Type Form of the Receptor by Finlay, M. Raymond V, Anderton, Mark, Ashton, Susan, Ballard, Peter, Bethel, Paul A, Box, Matthew R, Bradbury, Robert H, Brown, Simon J, Butterworth, Sam, Campbell, Andrew, Chorley, Christopher, Colclough, Nicola, Cross, Darren A. E, Currie, Gordon S, Grist, Matthew, Hassall, Lorraine, Hill, George B, James, Daniel, James, Michael, Kemmitt, Paul, Klinowska, Teresa, Lamont, Gillian, Lamont, Scott G, Martin, Nathaniel, McFarland, Heather L, Mellor, Martine J, Orme, Jonathon P, Perkins, David, Perkins, Paula, Richmond, Graham, Smith, Peter, Ward, Richard A, Waring, Michael J, Whittaker, David, Wells, Stuart, Wrigley, Gail L

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The evolution of eProtocols that enable reproducible clinical research and care methods by Blagev, Denitza P., Hirshberg, Eliotte L., Sward, Katherine, Thompson, B. Taylor, Brower, Roy, Truwit, Jonathon, Hite, Duncan, Steingrub, Jay, Orme, James F., Clemmer, Terry P., Weaver, Lindell K., Thomas, Frank, Grissom, Colin K., Sorenson, Dean, Sittig, Dean F., Wallace, C. Jane, East, Thomas D., Warner, Homer R., Morris, Alan H.

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Multicenter validation of a computer-based clinical decision support tool for glucose control in adult and pediatric intensive care units by Thompson, B Taylor, Orme, James F, Zheng, Hui, Luckett, Peter M, Truwit, Jonathon D, Willson, Douglas F, Duncan Hite, R, Brower, Roy G, Bernard, Gordon R, Curley, Martha A Q, Steingrub, Jay S, Sorenson, Dean K, Sward, Kathy, Hirshberg, Ellie, Morris, Alan H

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