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Physiological levels of folic acid reveal purine alterations in Lesch-Nyhan disease
by
López, José M.
,
Outtrim, Esther L.
,
Fu, Rong
,
Sutcliffe, Diane J.
,
Torres, Rosa J.
,
Jinnah, H. A.
Published in
Proceedings of the National Academy of Sciences - PNAS
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Proceedings Of The National Academy Of Sciences - Pnas
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Accumulation
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Adenosine Triphosphate
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Adenosine Triphosphate - Metabolism
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Aicar
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Aminoimidazole Carboxamide - Analogs & Derivatives
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Aminoimidazole Carboxamide - Metabolism
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Biological Sciences
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Brain
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Cell Culture Techniques
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Cerebrospinal Fluid
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Culture Media
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Culture Media, Conditioned - Chemistry
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Depletion
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Fibroblasts
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Fibroblasts - Metabolism
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Folic Acid
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Folic Acid - Analysis
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Guanine
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Humans
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Hyperuricemia
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