A Randomized Controlled Trial of Adaptive Ventilation for Cheyne-Stokes Breathing in Heart Failure by Pepperell, Justin C. T, Maskell, Nick A, Jones, David R, Langford-Wiley, Beverley A, Crosthwaite, Nicky, Stradling, John R, Davies, Robert J. O

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Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised parallel trial by Pepperell, Justin CT, Ramdassingh-Dow, Sharon, Crosthwaite, Nicky, Mullins, Rebecca, Jenkinson, Crispin, Stradling, John R, Davies, Robert JO

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Effect of Thoracoscopic Talc Poudrage vs Talc Slurry via Chest Tube on Pleurodesis Failure Rate Among Patients With Malignant Pleural Effusions: A Randomized Clinical Trial by Bhatnagar, Rahul, Piotrowska, Hania E. G, Laskawiec-Szkonter, Magda, Kahan, Brennan C, Luengo-Fernandez, Ramon, Pepperell, Justin C. T, Evison, Matthew D, Holme, Jayne, Al-Aloul, Mohamed, Psallidas, Ioannis, Lim, Wei Shen, Blyth, Kevin G, Roberts, Mark E, Cox, Giles, Downer, Nicola J, Herre, Jurgen, Sivasothy, Pasupathy, Menzies, Daniel, Munavvar, Mohammed, Kyi, Moe M, Ahmed, Liju, West, Alex G, Harrison, Richard N, Prudon, Benjamin, Hettiarachchi, Gihan, Chakrabarti, Biswajit, Kavidasan, Ajikumar, Sutton, Benjamin P, Zahan-Evans, Natalie J, Quaddy, Jack L, Edey, Anthony J, Clive, Amelia O, Walker, Steven P, Little, Matthew H. R, Mei, Xue W, Harvey, John E, Hooper, Clare E, Davies, Helen E, Slade, Mark, Sivier, Merle, Miller, Robert F, Rahman, Najib M, Maskell, Nick A

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Effects of Continuous Positive Airway Pressure on Quality of Life in Patients With Moderate to Severe Obstructive Sleep Apnea : Data From a Randomized Controlled Trial by SICCOLI, Massimiliano M, PEPPERELL, Justin C. T, KOHLER, Malcolm, CRAIG, Sonya E, DAVIES, Robert J. O, STRADLING, John R

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Continuous positive airway pressure treatment for obstructive sleep apnoea reduces resting heart rate but does not affect dysrhythmias: a randomised controlled trial by CRAIG, SONYA, PEPPERELL, JUSTIN C. T., KOHLER, MALCOLM, CROSTHWAITE, NICKY, DAVIES, ROBERT J. O., STRADLING, JOHN R.

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Effect of continuous positive airway pressure therapy on circadian patterns of cardiac repolarization in patients with obstructive sleep apnoea: data from a randomized trial by Schlatzer, Christian, Bratton, Daniel J, Schwarz, Esther I, Gaisl, Thomas, Pepperell, Justin C T, Stradling, John R, Kohler, Malcolm

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The ANDANTE Project: A Worldwide Individual Data Meta-Analysis of the Effect of Sleep Apnea Treatment on Blood Pressure by Pengo, Martino F., Steier, Joerg, Parati, Gianfranco, Ayas, Najib T., Barbé, Ferran, Barnes, Maree, Campos-Rodriguez, Francisco, Cistulli, Peter, Lloberes, Patricia, Craig, Sonya, Drager, Luciano F., Durán-Cantolla, Joaquín, Litvin and Evgeniya Elfimova, Alexander, Esra, Tasali, Giontella, Alice, Fava, Cristiano, Fuchs, Sandra Costa, Fuchs, Flávio Danni, Gagnadoux, Frédéric, García-Río, Francisco, Javaheri and Daniel J Gottlieb, Sogol, Hong, Geu-Ru, Grunstein, Ronald R., Hoyos, Camilla M., Joyeux-Faure, Marie, Liu, Peter Y., Lorenzi-Filho, Geraldo, Ip, Mary S.M., Lui, Macy M.S., Martínez-García, Miguel Ángel, McEvoy, Doug, Mehra, Reena, Monasterio, Carmen, McMillan, Alison, Morrell, Mary J., Pamidi, Sushmita, Pengo, Martino, Bilo, Grzegorz, Lombardi, Carolina, Parati, Gianfranco, Peker, Yüksel, Glos, Martin, Penzel, Thomas, Pépin, Jean-Louis, Pepperell, Justin C.T., Phillips, Craig L., Quan, Stuart F., Quinnell, Tim, Salles, Gil F, Salord, Neus, Sánchez-de-la-Torre, Manuel, Irene Schwarz, Esther, Shaw, Jonathan E., Shukla, Garima, Steier, Joerg, Stradling, John, Thunström, Erik, Wang, Ji-Guang, Weaver, Terri E., Zambon, Antonella, Soranna, Davide, Zambra, Gaia

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The ANDANTE Project: A Worldwide Individual Data Meta-Analysis of the Effect of Sleep Apnea Treatment on Blood Pressure by Pengo, Martino F, Steier, Joerg, Parati, Gianfranco

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Systemic hypertension and obstructive sleep apnoea by Pepperell, Justin C.T., Davies, Robert J.O., Stradling, John R.

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Mild obstructive sleep apnoea in females: post hoc analysis of the MERGE randomised controlled trial by Wimms, Alison J, Kelly, Julia L, Turnbull, Christopher D, McMillan, Alison, Craig, Sonya E, O'Reilly, John F, Nickol, Annabel H, Decker, Meredith D, Willes, Leslee A, Calverley, Peter M A, Benjafield, Adam V, Stradling, John R, Morrell, Mary J

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SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses by Wang, Beibei, Skelly, Donal, Pan, Daniel, Omo-Dare, Nicola, Koeckerling, David, Jenkin, Daniel, Fernandes da Costa, Cristiano, Malik, Tariq, Baillie, J. Kenneth, Klenerman, Paul, Pollard, Andrew J., Conlon, Christopher, Jeffery, Katie, Stafford, Lizzie, Chand, Meera, Green, Christoper A., Harrison, Ewen M., Wai Ho, Antonia Ying, Palmarini, Massimo, Price, Nicholas, Robertson, David L., Sigfrid, Louise, Sriskandan, Shiranee, Stuart, David, Swann, Olivia V., Tedder, Richard S., Turtle, Lance CW, Zambon, Maria, Pius, Riinu, Knight, Stephen R., Harrison, Janet, Jackson, Clare, Gamble, Carrol, Plotkin, Daniel, Lee, James, Wham, Murray, Shaw, Victoria, McDonald, Sarah E., Armstrong, Jane A., Ashworth, Milton, Barlow, Samantha L., Bullock, Katie, Davis, Christopher, Dunn, Chris, King, Katharine, Kiy, Robyn T., Lant, Suzannah, Latawiec, Diane, Mancini, Maria, Metelmann, Soeren, Penrice-Randal, Rebekah, Pilgrim, Jack, van Tonder, Libby, Murphy, Lee, Morrice, Kirstie, Gilchrist, Tammy, Aldera, Erin L., Barnass, Stella, Bernatoniene, Jolanta, Bothma, Pieter, Brittain-Long, Robin, Caruth, Vikki, Collini, Paul, Dawson, Chris, Dervisevic, Samir, Dushianthan, Ahilanadan, Evans, Cariad, Harvey, Daniel, Hawcutt, Daniel B., Hodgson, Luke, Hormis, Anil, Kerrison, Caroline, Larkin, Susan, Little, Jeff, Meda, Manjula, Moon, James, Mortimore, Katherine, Murphy, Michael, O’Shea, Matthew K., Otahal, Igor, Panchatsharam, Selva, Patel, Brij, Pepperell, Justin, Peters, Mark, Price, David, Reschreiter, Henrik, Ruge, Bobby, Saluja, Taranprit, Sizer, Jeremy, Shankar-Hari, Manu, Snelson, Catherine, Staines, Nikki, Twagira, Mary, Vincent-Smith, Lisa, Visuvanathan, Shico, Welters, Ingeborg, Wolverson, Adam, Yates, Bryan, Fry, Elizabeth E., Ren, Jingshan

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Prophylactic radiotherapy for the prevention of procedure-tract metastases after surgical and large-bore pleural procedures in malignant pleural mesothelioma (SMART): a multicentre... by Clive, Amelia O, PhD, Taylor, Hazel, MSc, Dobson, Lee, MBChB, Wilson, Paula, FRCR, de Winton, Emma, FRCR, Panakis, Niki, FRCR, Pepperell, Justin, MD, Howell, Timothy, DM, Stewart, Samuel A, PhD, Penz, Erika, FRCPC, Jordan, Nikki, MSc, Morley, Anna J, BSc, Zahan-Evans, Natalie, BSc, Smith, Sarah, BSc, Batchelor, Timothy J P, FRCS, Marchbank, Adrian, FRCS, Bishop, Lesley, MD, Ionescu, Alina A, MD, Bayne, Mike, MD, Cooper, Samantha, FRCP, Kerry, Anthony, FRCP, Jenkins, Peter, PhD, Toy, Elizabeth, FRCR, Vigneswaran, Vallipuram, MD, Gildersleve, James, FRCR, Ahmed, Merina, MD[Res], McDonald, Fiona, MD[Res], Button, Mick, MA, Lewanski, Conrad, FRCR, Comins, Charles, FRCR, Dakshinamoorthy, Muthukumar, FRCR, Lee, Y C Gary, Prof, Rahman, Najib M, DPhil, Maskell, Nick A, Prof

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Clinical characteristics of children and young people admitted to hospital with covid-19 in United Kingdom: prospective multicentre observational cohort study by Halpin, Sophie, Donohue, Chloe, Ladhani, Shamez, Horby, Peter W, Docherty, Annemarie B, Semple, Malcolm G, Openshaw, Peter J M, Bach, Benjamin, Chand, Meera, Harrison, Ewen M, Hiscox, Julian A, Horby, Peter W, Klenerman, Paul, Law, Andrew, Moore, Shona C, Palmarini, Massimo, Russell, Clark D, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Thomson, Emma C, Oosthuyzen, Wilna, Norman, Lisa, Pius, Riinu, Mclean, Kenneth A, Saviciute, Egle, Leeming, Gary, Hendry, Ross, Greenhalf, William, Ahmed, Katie A, Asiimwe, Innocent G, Brennan, Benjamin, Catterall, Benjamin WA, Clark, Jordan J, Cole, Sarah, Cox, Helen, Elliott, Angela, Foster, Terry, Greenhalf, Willliam, Jones, Trevor R, Murphy, Ellen G, Small, Benjamin, Subramaniam, Krishanthi S, Tanianis, Jolanta, Trochu, Erwan, van Tonder, Libby, Wilcock, Eve, Agranoff, Daniel, Angus, Brian, Atkinson, Dougal, Barlow, Gavin, Barrett, Nicholas, Bassford, Christopher, Beadsworth, Michael, Best, Nicola, Burden, Tom, Chukkambotla, Srikanth, Cupitt, Jason, Dark, Paul, Dushianthan, Ahilanadan, Dyer, Tristan, Evans, Cariad, Fegan, Christopher, Finn, Adam, Fullerton, Duncan, Goldsmith, Arthur, Hardy, Elaine, Havalda, Peter, Holme, Anita, Kendall, Jason, Kerrison, Caroline, Larkin, Susan, Leiner, Tamas, Lillie, Patrick, MacNaughton, Emily, McCullough, Katherine, Moore, Elinoor, Morgan, Patrick, Morris, Craig, Nelson, Mark, Panchatsharam, Selva, Pintus, Stefania, Prout, Rachel, Rousseau, Guy, Ryan, Brendan, Saluja, Taranprit, Shanmuga, Prad, Sharma, Anil, Sizer, Jeremy, Smith, Richard, Snelson, Catherine, Spittle, Nick, Stambach, Tom, Tridente, Ascanio, Ustianowski, Andrew, Waddy, Sam, Whittaker, Paul, Williams, Martin, Wiselka, Martin, Young, Peter

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Characterisation of in-hospital complications associated with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol UK: a prospective, multicentre cohort study by Knight, Stephen R, Holden, Karl A, Merson, Laura, Russell, Clark D, Solomon, Tom, Carson, Gail, Olliaro, Piero, Semple, Malcolm G, Alex, Beatrice, Bach, Benjamin, Dunning, Jake, da Silva Filipe, Ana, Horby, Peter W, Law, Andrew, Price, Nicholas, Rambaut, Andrew, Robertson, David L, Scott, Janet T, de Silva, Thushan, Sigfrid, Louise, Tedder, Richard S, Thwaites, Ryan S, Turtle, Lance CW, Andrikopoulos, Petros, Liggi, Sonia, Sands, Caroline, Fairfield, Cameron J, Shaw, Catherine A, Dalton, Jo, Girvan, Michelle, Hendry, Ross, Greenhalf, William, McDonald, Sarah E, Booth, Laura, Catterall, Benjamin WA, Clarke, Emily A, Dincarslan, Oslem, Dyer, Philip, Gunning, Philip, Hartley, Catherine, Jensen, Rebecca L, Jones, Christopher B, Khandaker, Shadia, Lefteri, Daniella, Livoti, Lucia A, Middleton, Joanna, Reynolds, Will, Ridley, P. Matthew, Shaw, Victoria E, Tanianis-Hughes, Jolanta, Trochu, Erwan, Flaherty, Lisa, Massey, Hannah, Aldera, Erin L., Alegria, Ana, Barnass, Stella, Barrett, Nicholas, Basude, Sneha, Baxter, David, Beadsworth, Michael, Best, Nicola, Burden, Tom, Chukkambotla, Srikanth, Cutino-Moguel, Maria-Teresa, Douthwaite, Sam, Fullerton, Duncan, Garg, Atul, Hawcutt, Daniel B, Jennings, Paul, Kaliappan, Agilan, Kasipandian, Vidya, Koduri, Gouri, Laird, Steven, Leiner, Tamas, Little, Jeff, McEwen, Ruth, Morris, Craig, Moses, Samuel, Norris, Lillian, Panchatsharam, Selva, Pattison, Natalie, Peters, Mark, Price, David, Prout, Rachel, Richardson, Neil, Rousseau, Guy, Ryan, Brendan, Sharma, Anil, Stambach, Tom, Stewart, Richard, Thompson, Robert, Tridente, Ascanio, Vuylsteke, Alan, Waddy, Sam, Wake, Rachel, Wilson, Lawrence, Wiselka, Martin, Wootton, Daniel G, Workman, Andrew, Young, Peter

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Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion: The TIME1 Randomized Clin... by Rahman, Najib M, Pepperell, Justin, Rehal, Sunita, Saba, Tarek, Tang, Augustine, Ali, Nabeel, West, Alex, Hettiarachchi, Gihan, Mukherjee, Dipak, Samuel, Johnson, Bentley, Andrew, Dowson, Lee, Miles, Jonathan, Ryan, C. Frank, Yoneda, Ken Y, Chauhan, Anoop, Corcoran, John P, Psallidas, Ioannis, Wrightson, John M, Hallifax, Rob, Davies, Helen E, Lee, Y. C. Gary, Dobson, Melissa, Hedley, Emma L, Seaton, Douglas, Russell, Nicky, Chapman, Margaret, McFadyen, Bethan M, Shaw, Rachel A, Davies, Robert J. O, Maskell, Nick A, Nunn, Andrew J, Miller, Robert F

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Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP-UK study: a multicentre, pr... by Fairfield, Cameron J, Drake, Thomas M, Sigfrid, Louise, Docherty, Annemarie B, Girvan, Michelle, Dunning, Jake, Openshaw, Peter J M, Openshaw, Peter JM, Bach, Benjamin, Chand, Meera, Harrison, Ewen M, Hiscox, Julian A, Law, Andrew, Merson, Laura, Moore, Shona C, Russell, Clark D, Solomon, Tom, Sriskandan, Shiranee, Stuart, David, Tedder, Richard S, Palmieri, Carlo, Knight, Stephen R, Shaw, Catherine A, Marsh, Laura, Shaw, Victoria, McDonald, Sarah E, Keating, Seán, Armstrong, Jane A, Ashworth, Milton, Booth, Laura, Brennan, Benjamin, Bullock, Katie, Cooper, Louise, Davis, Christopher, Dincarslan, Oslem, Dunn, Chris, Evans, Anthony, Garcia-Dorival, Isabel, Jones, Christopher B, Khandaker, Shadia, Lant, Suzannah, Lavelle-Langham, Lara, Lefteri, Daniella, Lett, Lauren, Livoti, Lucia A, Mancini, Maria, McLauchlan, John, Murphy, Ellen G, Penrice-Randal, Rebekah, Pilgrim, Jack, Small, Benjamin, Subramaniam, Krishanthi S, Tanianis-Hughes, Jolanta, van Tonder, Libby, Wilcock, Eve, Flaherty, Lisa, MacLean, Alan, Agranoff, Daniel, Aldera, Erin L., Alegria, Ana, Bari, Shahedal, Barlow, Gavin, Barnass, Stella, Basude, Sneha, Chadwick, David, Chee, Nigel, Chukkambotla, Srikanth, Cutino-Moguel, Maria-Teresa, Dark, Paul, Donnison, Phil, Douthwaite, Sam, Dushianthan, Ahilanadan, Eziefula, Chi, Fegan, Chrisopher, Garg, Atul, Hawcutt, Daniel B, Hobrok, Maria, Jennings, Paul, Koduri, Gouri, Laha, Shondipon, Laird, Steven, MacNaughton, Emily, Mankregod, Ravish, Masson, Huw, McCullough, Katherine, Mirfenderesky, Mariyam, Mohandas, Kavya, Morris, Craig, Nagel, Megan, Papakonstantino, Danai, Pintus, Stefania, Singh Pooni, Jagtur, Prout, Rachel, Roberts, Devender, Rose, Alistair, Shawcross, Anna, Tatham, Kate, Vuylsteke, Alan, Whittaker, Paul, Wiselka, Martin

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The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection by Goldswain, Hannah, Dong, Xiaofeng, Penrice-Randal, Rebekah, Alruwaili, Muhannad, Shawli, Ghada T, Prince, Tessa, Williamson, Maia Kavanagh, Raghwani, Jayna, Randle, Nadine, Jones, Benjamin, Donovan-Banfield, I'ah, Salguero, Francisco J, Tree, Julia A, Hall, Yper, Hartley, Catherine, Erdmann, Maximilian, Bazire, James, Jearanaiwitayakul, Tuksin, Semple, Malcolm G, Openshaw, Peter J M, Baillie, J Kenneth, Emmett, Stevan R, Digard, Paul, Matthews, David A, Turtle, Lance, Darby, Alistair C, Davidson, Andrew D, Carroll, Miles W, Hiscox, Julian A

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Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses by Michael, Benedict D., Dunai, Cordelia, Needham, Edward J., Tharmaratnam, Kukatharmini, Williams, Robyn, Huang, Yun, Boardman, Sarah A., Clark, Jordan J., Sharma, Parul, Subramaniam, Krishanthi, Wood, Greta K., Collie, Ceryce, Digby, Richard, Ren, Alexander, Norton, Emma, Leibowitz, Maya, Ebrahimi, Soraya, Fower, Andrew, Fox, Hannah, Tato, Esteban, Ellul, Mark A., Sunderland, Geraint, Held, Marie, Hetherington, Claire, Egbe, Franklyn N., Palmos, Alish, Stirrups, Kathy, Grundmann, Alexander, Chiollaz, Anne-Cecile, Sanchez, Jean-Charles, Stewart, James P., Griffiths, Michael, Solomon, Tom, Breen, Gerome, Coles, Alasdair J., Kingston, Nathalie, Bradley, John R., Chinnery, Patrick F., Cavanagh, Jonathan, Irani, Sarosh R., Vincent, Angela, Baillie, J. Kenneth, Openshaw, Peter J., Semple, Malcolm G., Taams, Leonie S., Menon, David K.

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Randomized Controlled Trial of Urokinase versus Placebo for Nondraining Malignant Pleural Effusion by Mishra, Eleanor K, Clive, Amelia O, Wills, Genevieve H, Davies, Helen E, Stanton, Andrew E, Al-Aloul, Mohamed, Hart-Thomas, Alan, Pepperell, Justin, Evison, Matthew, Saba, Tarek, Harrison, Richard Neil, Guhan, Anur, Callister, Matthew E, Sathyamurthy, Ramamurthy, Rehal, Sunita, Corcoran, John P, Hallifax, Robert, Psallidas, Ioannis, Russell, Nicky, Shaw, Rachel, Dobson, Melissa, Wrightson, John M, West, Alex, Lee, Y C Gary, Nunn, Andrew J, Miller, Robert F, Maskell, Nick A, Rahman, Najib M

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Burden of SARS-CoV-2 infection in healthcare workers during second wave in England and impact of vaccines: prospective multicentre cohort study (SIREN) and mathematical model by Pople, Diane, Monk, Edward J M, Robotham, Julie, Hall, Victoria J, Adebiyi, Omoyeni, Akhtar, Talat, Aldridge, N, Ambalkar, Shrikant, Ashton, Maxine, Auckland, Cressida, Baillon, Sarah, Barnes, T, Bateman, Vhairi, Black, Karen, Brookes, Claire, Calbraith, Davina, Charlett, Andre, Colton, James, Cowley, Anna, Crosby-Nwaobi, Roxanne, Crowe, Jane, Dave, Ananta, Dawson, Joy, Democratis, Jane, Diaz, Stephanie, Dimmer, Allison, Dobbie, Laura, Duff, Christopher, Easom, Nicholas, Elumogo, Ngozi, Favager, Clair, Frieslick, Joan, Froude, Susannah, Galliford, Joanne, Game, F, Giles, J, Grant, Alison, Gray, Kim, Hams, Steve, Harman, Paula, Harris, Penny, Hawkins, April, Hettiarachchi, Nipunadi, Higham, Andrew, Hollinshead, Kathryn, Horsley, A, Howard, Joanne, Huang, Y, Hudson, Karen, Irvine, Val, Jones, C, Jorgenson, Annelysse, Kalakonda, Nagesh, Keogh, Siobhan, Kerrison, C, Khawam, Jameel, Larru, A, Lazarus, Rajeka, Linley, Ezra, Longfellow, Ruth, Luckas, Murray, Mackay, Shekoo, Malcolm, Martin, Maxwell, V, McCracken, Danielle, Milligan, Iain, Mistry, Raksha, Moran, Kelly, Murphy, Michael, Nash, Maxine, O'Kelly, A, Otter, Ashley, Patel, Manish, Pepper, Stacey, Pethick, James, Planche, Tim, Plant, Aiden, Powell, James, Prince, Stephanie, Jones, Rowan Pritchard, Rajgopal, A, Ramsay, Mary, Reynolds, T, Richardson, Lisa, Robinson, L, Roynon, Anna, Saei, Ayoub, Shah, A, Sinclair, Janet, Sovriarova, Helena, Stafford, Claire, Stewart, B, Taylor-Kerr, Andrew, Telfer, Andrew, Watson, Ekaterina, Weir, Jennifer, Williams, M, Willshaw, Stephanie, Young, Charlotte, Zheng, Qi

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