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Mebendazole is unique among tubulin-active drugs in activating the MEK–ERK pathway
by
Andersson, Claes R.
,
Selvin, Tove
,
Blom, Kristin
,
Rubin, Jenny
,
Berglund, Malin
,
Jarvius, Malin
,
Lenhammar, Lena
,
Parrow, Vendela
,
Loskog, Angelica
,
Fryknäs, Mårten
,
Nygren, Peter
,
Larsson, Rolf
Published in
Scientific reports
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Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition
by
Blom, Kristin
,
Rubin, Jenny
,
Berglund, Malin
,
Jarvius, Malin
,
Lenhammar, Lena
,
Parrow, Vendela
,
Andersson, Claes
,
Loskog, Angelica
,
Fryknäs, Mårten
,
Nygren, Peter
,
Larsson, Rolf
Published in
BMC research notes
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AKN-028 induces cell cycle arrest, downregulation of Myc associated genes and dose dependent reduction of tyrosine kinase activity in acute myeloid leukemia
by
Eriksson, Anna
,
Kalushkova, Antonia
,
Jarvius, Malin
,
Hilhorst, Riet
,
Rickardson, Linda
,
Kultima, Hanna Göransson
,
de Wijn, Rik
,
Hovestad, Liesbeth
,
Fryknäs, Mårten
,
Öberg, Fredrik
,
Larsson, Rolf
,
Parrow, Vendela
,
Höglund, Martin
Published in
Biochemical pharmacology
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Abstract 3843: LSD1 modulation by allosteric ligands
by
Emond, Wei B.
,
Geitmann, Matthis
,
Jarvius, Malin
,
Koehler, Konrad
,
Källblad, Per
,
Niklasson, Mia
,
Parrow, Vendela
,
Sawant, Rajiv
,
Sjöberg, Maria
,
Winquist, Johan
,
Segerman, Anna
,
Bremberg, Ulf
Published in
Cancer research (Chicago, Ill.)
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The anticancer effect of mebendazole may be due to M1 monocyte/macrophage activation via ERK1/2 and TLR8-dependent inflammasome activation
by
Blom, Kristin
,
Senkowski, Wojciech
,
Jarvius, Malin
,
Berglund, Malin
,
Rubin, Jenny
,
Lenhammar, Lena
,
Parrow, Vendela
,
Andersson, Claes
,
Loskog, Angelica
,
Fryknäs, Mårten
,
Nygren, Peter
,
Larsson, Rolf
Published in
Immunopharmacology and immunotoxicology
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Abstract 705: Potentiation of immunotherapy by LSD1 modulation
by
Emond, Wei B.
,
Sawant, Rajiv
,
Geitmann, Matthis
,
Winquist, Johan
,
Brandt, Peter
,
Bremberg, Ulf
,
Källblad, Per
,
Parrow, Vendela
,
Andersson, Claes
,
Blom, Kristin
,
Najafi, Nasrin
,
Bergström, Tobias
,
Swartling, Fredrik J.
,
Hellström, Mats
,
Koehler, Konrad F.
Published in
Cancer research (Chicago, Ill.)
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Picropodophyllin causes mitotic arrest and catastrophe by depolymerizing microtubules via insulin-like growth factor-1 receptor-independent mechanism
by
Waraky, Ahmed
,
Akopyan, Karen
,
Parrow, Vendela
,
Strömberg, Thomas
,
Axelson, Magnus
,
Abrahmsén, Lars
,
Lindqvist, Arne
,
Larsson, Olle
,
Aleem, Eiman
Published in
Oncotarget
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AKN-028 induces cell cycle arrest, downregulation of Myc associated genes and a dose dependent reduction of kinase activity in acute myeloid leukemia
by
Eriksson, Anna
,
Kalushkova, Antonia
,
Jarvius, Malin
,
Hilhorst, Riet
,
Rickardson, Linda
,
Göransson Kultima, Hanna
,
de Wijn, Rik
,
Fryknäs, Mårten
,
Öberg, Fredrik
,
Larsson, Rolf
,
Parrow, Vendela
,
Höglund, Martin
Published in
Biochemical pharmacology
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AKN-028, a FLT-3 Kinase Inhibitor In Preclinical Development, Induces Significant Gene Regulation That Differs From PKC-412
by
Parrow, Vendela C
,
Eriksson, Anna
,
Göransson, Hanna
,
Rickardson, Linda
,
Lehmann, Fredrik
,
Lenhammar, Lena
,
Larsson, Rolf
,
Hoglund, Martin
Published in
Blood
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Identification of AKN-032, a novel 2-aminopyrazine tyrosine kinase inhibitor, with significant preclinical activity in acute myeloid leukemia
by
Eriksson, Anna
,
Höglund, Martin
,
Lindhagen, Elin
,
Åleskog, Anna
,
Hassan, Sadia Bashir
,
Ekholm, Carina
,
Fhölenhag, Karin
,
Jensen, Annika Jenmalm
,
Löthgren, Agneta
,
Scobie, Martin
,
Larsson, Rolf
,
Parrow, Vendela
Published in
Biochemical pharmacology
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In vivo evaluation of a novel, orally bioavailable, small molecule growth hormone receptor antagonist
by
Rosengren, Linda
,
Parrow, Vendela
,
Chmielewska, Joanna
,
Mode, Agneta
,
Fhölenhag, Karin
Published in
Growth hormone & IGF research
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Antisense and Sense RNA Probe Hybridization to Immobilized Crude Cellular Lysates: A Tool to Screen Growth Hormone Antagonists
by
Rosengren, Linda
,
Simko, Hanna
,
Aryan, Ladan
,
Axelsson-Lendin, Pia
,
Chmielewska, Joanna
,
Mode, Agneta
,
Parrow, Vendela
Published in
SLAS discovery
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