A2AR Adenosine Signaling Suppresses Natural Killer Cell Maturation in the Tumor Microenvironment by Young, Arabella, Ngiow, Shin Foong, Gao, Yulong, Patch, Ann-Marie, Barkauskas, Deborah S, Messaoudene, Meriem, Lin, Gene, Coudert, Jerome D, Stannard, Kimberley A, Zitvogel, Laurence, Degli-Esposti, Mariapia A, Vivier, Eric, Waddell, Nicola, Linden, Joel, Huntington, Nicholas D, Souza-Fonseca-Guimaraes, Fernando, Smyth, Mark J

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Whole-genome landscape of mucosal melanoma reveals diverse drivers and therapeutic targets by Newell, Felicity, Kong, Yan, Wilmott, James S., Johansson, Peter A., Ferguson, Peter M., Cui, Chuanliang, Li, Zhongwu, Kazakoff, Stephen H., Burke, Hazel, Dodds, Tristan J., Patch, Ann-Marie, Nones, Katia, Tembe, Varsha, Shang, Ping, van der Weyden, Louise, Wong, Kim, Holmes, Oliver, Lo, Serigne, Leonard, Conrad, Wood, Scott, Xu, Qinying, Rawson, Robert V., Mukhopadhyay, Pamela, Dummer, Reinhard, Levesque, Mitchell P., Jönsson, Göran, Wang, Xuan, Yeh, Iwei, Wu, Hong, Joseph, Nancy, Bastian, Boris C., Long, Georgina V., Spillane, Andrew J., Shannon, Kerwin F., Thompson, John F., Saw, Robyn P. M., Adams, David J., Si, Lu, Pearson, John V., Hayward, Nicholas K., Waddell, Nicola, Mann, Graham J., Guo, Jun, Scolyer, Richard A.

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A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing by Alioto, Tyler S., Buchhalter, Ivo, Derdak, Sophia, Hutter, Barbara, Eldridge, Matthew D., Hovig, Eivind, Heisler, Lawrence E., Beck, Timothy A., Simpson, Jared T., Tonon, Laurie, Sertier, Anne-Sophie, Patch, Ann-Marie, Jäger, Natalie, Ginsbach, Philip, Drews, Ruben, Paramasivam, Nagarajan, Kabbe, Rolf, Chotewutmontri, Sasithorn, Diessl, Nicolle, Previti, Christopher, Schmidt, Sabine, Brors, Benedikt, Feuerbach, Lars, Heinold, Michael, Gröbner, Susanne, Korshunov, Andrey, Tarpey, Patrick S., Butler, Adam P., Hinton, Jonathan, Jones, David, Menzies, Andrew, Raine, Keiran, Shepherd, Rebecca, Stebbings, Lucy, Teague, Jon W., Ribeca, Paolo, Giner, Francesc Castro, Beltran, Sergi, Raineri, Emanuele, Dabad, Marc, Heath, Simon C., Gut, Marta, Denroche, Robert E., Harding, Nicholas J., Yamaguchi, Takafumi N., Fujimoto, Akihiro, Nakagawa, Hidewaki, Quesada, Víctor, Valdés-Mas, Rafael, Nakken, Sigve, Vodák, Daniel, Bower, Lawrence, Lynch, Andrew G., Anderson, Charlotte L., Waddell, Nicola, Pearson, John V., Grimmond, Sean M., Peto, Myron, Spellman, Paul, He, Minghui, Kandoth, Cyriac, Lee, Semin, Zhang, John, Létourneau, Louis, Ma, Singer, Seth, Sahil, Torrents, David, Xi, Liu, Wheeler, David A., López-Otín, Carlos, Campo, Elías, Campbell, Peter J., Boutros, Paul C., Puente, Xose S., Gerhard, Daniela S., Pfister, Stefan M., McPherson, John D., Hudson, Thomas J., Schlesner, Matthias, Lichter, Peter, Eils, Roland, Jones, David T. W., Gut, Ivo G.

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Whole genome sequencing of melanomas in adolescent and young adults reveals distinct mutation landscapes and the potential role of germline variants in disease susceptibility by Wilmott, James S., Johansson, Peter A., Newell, Felicity, Waddell, Nicola, Ferguson, Peter, Quek, Camelia, Patch, Ann‐Marie, Nones, Katia, Shang, Ping, Pritchard, Antonia L., Kazakoff, Stephen, Holmes, Oliver, Leonard, Conrad, Wood, Scott, Xu, Qinying, Saw, Robyn P. M., Spillane, Andrew J., Stretch, Jonathan R., Shannon, Kerwin F., Kefford, Richard F., Menzies, Alexander M., Long, Georgina V., Thompson, John F., Pearson, John V., Mann, Graham J., Hayward, Nicholas K., Scolyer, Richard A.

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Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis by Nones, Katia, Waddell, Nicola, Wayte, Nicci, Patch, Ann-Marie, Bailey, Peter, Newell, Felicity, Holmes, Oliver, Fink, J. Lynn, Quinn, Michael C. J., Tang, Yue Hang, Lampe, Guy, Quek, Kelly, Loffler, Kelly A., Manning, Suzanne, Idrisoglu, Senel, Miller, David, Xu, Qinying, Waddell, Nick, Wilson, Peter J., Bruxner, Timothy J. C., Christ, Angelika N., Harliwong, Ivon, Nourse, Craig, Nourbakhsh, Ehsan, Anderson, Matthew, Kazakoff, Stephen, Leonard, Conrad, Wood, Scott, Simpson, Peter T., Reid, Lynne E., Krause, Lutz, Hussey, Damian J., Watson, David I., Lord, Reginald V., Nancarrow, Derek, Phillips, Wayne A., Gotley, David, Smithers, B. Mark, Whiteman, David C., Hayward, Nicholas K., Campbell, Peter J., Pearson, John V., Grimmond, Sean M., Barbour, Andrew P.

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Genome‐wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT‐ROBO, ITGA2 and MET signaling by Nones, Katia, Waddell, Nic, Song, Sarah, Patch, Ann‐Marie, Miller, David, Johns, Amber, Wu, Jianmin, Kassahn, Karin S., Wood, David, Bailey, Peter, Fink, Lynn, Manning, Suzanne, Christ, Angelika N., Nourse, Craig, Kazakoff, Stephen, Taylor, Darrin, Leonard, Conrad, Chang, David K., Jones, Marc D., Thomas, Michelle, Watson, Clare, Pinese, Mark, Cowley, Mark, Rooman, Ilse, Pajic, Marina, Butturini, Giovanni, Malpaga, Anna, Corbo, Vincenzo, Crippa, Stefano, Falconi, Massimo, Zamboni, Giuseppe, Castelli, Paola, Lawlor, Rita T., Gill, Anthony J., Scarpa, Aldo, Pearson, John V., Biankin, Andrew V., Grimmond, Sean M.

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Evaluating Diff‐Quik cytology smears for large‐panel mutation testing in lung cancer—Predicting DNA content and success with low‐malignant‐cellularity samples by Fielding, David I., Dalley, Andrew J., Singh, Mahendra, Nandakumar, Lakshmy, Lakis, Vanessa, Chittoory, Haarika, Fairbairn, David, Patch, Ann‐Marie, Kazakoff, Stephen H., Ferguson, Kaltin, Bashirzadeh, Farzad, Bint, Michael, Pahoff, Carl, Son, Jung Hwa, Hodgson, Alan, Sharma, Sowmya, Waddell, Nicola, Lakhani, Sunil R., Hartel, Gunter, Nones, Katia, Simpson, Peter T.

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EIF1AX and NRAS Mutations Co-occur and Cooperate in Low-Grade Serous Ovarian Carcinomas by Etemadmoghadam, Dariush, Azar, Walid J, Lei, Ying, Moujaber, Tania, Garsed, Dale W, Kennedy, Catherine J, Fereday, Sian, Mitchell, Chris, Chiew, Yoke-Eng, Hendley, Joy, Sharma, Raghwa, Harnett, Paul R, Li, Jason, Christie, Elizabeth L, Patch, Ann-Marie, George, Joshy, Au-Yeung, George, Mir Arnau, Gisela, Holloway, Timothy P, Semple, Timothy, Pearson, John V, Waddell, Nicola, Grimmond, Sean M, Köbel, Martin, Rizos, Helen, Lomakin, Ivan B, Bowtell, David D L, deFazio, Anna

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Insulin gene mutations as a cause of permanent neonatal diabetes by Støy, Julie, Edghill, Emma L, Flanagan, Sarah E, Ye, Honggang, Paz, Veronica P, Pluzhnikov, Anna, Below, Jennifer E, Hayes, M. Geoffrey, Cox, Nancy J, Lipkind, Gregory M, Lipton, Rebecca B, Greeley, Siri Atma W, Patch, Ann-Marie, Ellard, Sian, Steiner, Donald F, Hattersley, Andrew T, Philipson, Louis H, Bell, Graeme I

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Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation in CIDEC by Rubio‐Cabezas, Oscar, Puri, Vishwajeet, Murano, Incoronata, Saudek, Vladimir, Semple, Robert K., Dash, Satya, Hyden, Caroline S. S., Bottomley, William, Vigouroux, Corinne, Magré, Jocelyne, Raymond‐Barker, Philippa, Murgatroyd, Peter R., Chawla, Anil, Skepper, Jeremy N., Chatterjee, V. Krishna, Suliman, Sara, Patch, Ann‐Marie, Agarwal, Anil K., Garg, Abhimanyu, Barroso, Inês, Cinti, Saverio, Czech, Michael P., Argente, Jesús, O'Rahilly, Stephen, Savage, David B.

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Germline and somatic variant identification using BGISEQ-500 and HiSeq X Ten whole genome sequencing by Patch, Ann-Marie, Nones, Katia, Kazakoff, Stephen H, Newell, Felicity, Wood, Scott, Leonard, Conrad, Holmes, Oliver, Xu, Qinying, Addala, Venkateswar, Creaney, Jenette, Robinson, Bruce W, Fu, Shujin, Geng, Chunyu, Li, Tong, Zhang, Wenwei, Liang, Xinming, Rao, Junhua, Wang, Jiahao, Tian, Mingyu, Zhao, Yonggang, Teng, Fei, Gou, Honglan, Yang, Bicheng, Jiang, Hui, Mu, Feng, Pearson, John V, Waddell, Nicola

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Recessive mutations in the INS gene result in neonatal diabetes through reduced insulin biosynthesis by Garin, Intza, Edghill, Emma L, Akerman, Ildem, Rubio-Cabezas, Oscar, Rica, Itxaso, Locke, Jonathan M, Maestro, Miguel Angel, Alshaikh, Adnan, Bundak, Ruveyde, del Castillo, Gabriel, Deeb, Asma, Deiss, Dorothee, Fernandez, Juan M, Godbole, Koumudi, Hussain, Khalid, O'Connell, Michele, Klupa, Thomasz, Kolouskova, Stanislava, Mohsin, Fauzia, Perlman, Kusiel, Sumnik, Zdenek, Rial, Jose M, Ugarte, Estibaliz, Vasanthi, Thiruvengadam, Johnstone, Karen, Flanagan, Sarah E, Martínez, Rosa, Castaño, Carlos, Patch, Ann-Marie, Fernández-Rebollo, Eduardo, Raile, Klemens, Morgan, Noel, Harries, Lorna W, Castaño, Luis, Ellard, Sian, Ferrer, Jorge, de Nanclares, Guiomar Perez, Hattersley, Andrew T

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Unexpected UVR and non-UVR mutation burden in some acral and cutaneous melanomas by Rawson, Robert V, Johansson, Peter A, Hayward, Nicholas K, Waddell, Nicola, Patch, Ann-Marie, Lo, Serigne, Pearson, John V, Thompson, John F, Mann, Graham J, Scolyer, Richard A, Wilmott, James S

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Injection site vaccinology of a recombinant vaccinia-based vector reveals diverse innate immune signatures by Hazlewood, Jessamine E, Dumenil, Troy, Le, Thuy T, Slonchak, Andrii, Kazakoff, Stephen H, Patch, Ann-Marie, Gray, Lesley-Ann, Howley, Paul M, Liu, Liang, Hayball, John D, Yan, Kexin, Rawle, Daniel J, Prow, Natalie A, Suhrbier, Andreas

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Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer by Bonazzi, Vanessa F, Kondrashova, Olga, Smith, Deborah, Nones, Katia, Sengal, Asmerom T, Ju, Robert, Packer, Leisl M, Koufariotis, Lambros T, Kazakoff, Stephen H, Davidson, Aimee L, Ramarao-Milne, Priya, Lakis, Vanessa, Newell, Felicity, Rogers, Rebecca, Davies, Claire, Nicklin, James, Garrett, Andrea, Chetty, Naven, Perrin, Lewis, Pearson, John V, Patch, Ann-Marie, Waddell, Nicola, Pollock, Pamela M

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Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer by Kane, Alexandra M., Fennell, Lochlan J., Liu, Cheng, Borowsky, Jennifer, McKeone, Diane M., Bond, Catherine E., Kazakoff, Stephen, Patch, Ann-Marie, Koufariotis, Lambros T., Pearson, John, Waddell, Nicola, Leggett, Barbara A., Whitehall, Vicki L.J.

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Wolcott-Rallison Syndrome Is the Most Common Genetic Cause of Permanent Neonatal Diabetes in Consanguineous Families by Rubio-Cabezas, Oscar, Patch, Ann-Marie, Minton, Jayne A. L., Flanagan, Sarah E., Edghill, Emma L., Hussain, Khalid, Balafrej, Amina, Deeb, Asma, Buchanan, Charles R., Jefferson, Ian G., Mutair, Angham, Hattersley, Andrew T., Ellard, Sian

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Whole exome sequencing of an asbestos-induced wild-type murine model of malignant mesothelioma by Sneddon, Sophie, Patch, Ann-Marie, Dick, Ian M, Kazakoff, Stephen, Pearson, John V, Waddell, Nicola, Allcock, Richard J N, Holt, Robert A, Robinson, Bruce W S, Creaney, Jenette

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Somatic point mutation calling in low cellularity tumors by Kassahn, Karin S, Holmes, Oliver, Nones, Katia, Patch, Ann-Marie, Miller, David K, Christ, Angelika N, Harliwong, Ivon, Bruxner, Timothy J, Xu, Qinying, Anderson, Matthew, Wood, Scott, Leonard, Conrad, Taylor, Darrin, Newell, Felicity, Song, Sarah, Idrisoglu, Senel, Nourse, Craig, Nourbakhsh, Ehsan, Manning, Suzanne, Wani, Shivangi, Steptoe, Anita, Pajic, Marina, Cowley, Mark J, Pinese, Mark, Chang, David K, Gill, Anthony J, Johns, Amber L, Wu, Jianmin, Wilson, Peter J, Fink, Lynn, Biankin, Andrew V, Waddell, Nicola, Grimmond, Sean M, Pearson, John V

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Mutation load in melanoma is affected by MC1R genotype by Johansson, Peter A., Pritchard, Antonia L., Patch, Ann‐Marie, Wilmott, James S., Pearson, John V., Waddell, Nicola, Scolyer, Richard A., Mann, Graham J., Hayward, Nicholas K.

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