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Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity
by
Mabanglo, Mark F.
,
Wilson, Brian
,
Noureldin, Mahmoud
,
Kimani, Serah W.
,
Mamai, Ahmed
,
Krausser, Chiara
,
González-Álvarez, Héctor
,
Srivastava, Smriti
,
Mohammed, Mohammed
,
Hoffer, Laurent
,
Chan, Manuel
,
Avrumutsoae, Jamie
,
Li, Alice Shi Ming
,
Hajian, Taraneh
,
Tucker, Sarah
,
Green, Stuart
,
Szewczyk, Magdalena
,
Barsyte-Lovejoy, Dalia
,
Santhakumar, Vijayaratnam
,
Ackloo, Suzanne
,
Loppnau, Peter
,
Li, Yanjun
,
Seitova, Almagul
,
Kiyota, Taira
,
Wang, Jue George
,
Privé, Gilbert G.
,
Kuntz, Douglas A.
,
Patel, Bhashant
,
Rathod, Vaibhavi
,
Vala, Anand
,
Rout, Bhimsen
,
Aman, Ahmed
,
Poda, Gennady
,
Uehling, David
,
Ramnauth, Jailall
,
Halabelian, Levon
,
Marcellus, Richard
,
Al-awar, Rima
,
Vedadi, Masoud
Published in
Nature communications
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Discovery of Nanomolar DCAF1 Small Molecule Ligands
by
Li, Alice Shi Ming
,
Kimani, Serah
,
Wilson, Brian
,
Noureldin, Mahmoud
,
González-Álvarez, Héctor
,
Mamai, Ahmed
,
Hoffer, Laurent
,
Guilinger, John P.
,
Zhang, Ying
,
von Rechenberg, Moritz
,
Disch, Jeremy S.
,
Mulhern, Christopher J.
,
Slakman, Belinda L.
,
Cuozzo, John W.
,
Dong, Aiping
,
Poda, Gennady
,
Mohammed, Mohammed
,
Saraon, Punit
,
Mittal, Manish
,
Modh, Pratik
,
Rathod, Vaibhavi
,
Patel, Bhashant
,
Ackloo, Suzanne
,
Santhakumar, Vijayaratnam
,
Szewczyk, Magdalena M
,
Barsyte-Lovejoy, Dalia
,
Arrowsmith, Cheryl H.
,
Marcellus, Richard
,
Guié, Marie-Aude
,
Keefe, Anthony D.
,
Brown, Peter J.
,
Halabelian, Levon
,
Al-awar, Rima
,
Vedadi, Masoud
Published in
Journal of medicinal chemistry
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