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Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy by Al-Olabi, Lara, Polubothu, Satyamaanasa, Dowsett, Katherine, Andrews, Katrina A, Stadnik, Paulina, Joseph, Agnel P, Knox, Rachel, Pittman, Alan, Clark, Graeme, Baird, William, Bulstrode, Neil, Glover, Mary, Gordon, Kristiana, Hargrave, Darren, Huson, Susan M, Jacques, Thomas S, James, Gregory, Kondolf, Hannah, Kangesu, Loshan, Keppler-Noreuil, Kim M, Khan, Amjad, Lindhurst, Marjorie J, Lipson, Mark, Mansour, Sahar, O'Hara, Justine, Mahon, Caroline, Mosica, Anda, Moss, Celia, Murthy, Aditi, Ong, Juling, Parker, Victoria E, Rivière, Jean-Baptiste, Sapp, Julie C, Sebire, Neil J, Shah, Rahul, Sivakumar, Branavan, Thomas, Anna, Virasami, Alex, Waelchli, Regula, Zeng, Zhiqiang, Biesecker, Leslie G, Barnacle, Alex, Topf, Maya, Semple, Robert K, Patton, E Elizabeth, Kinsler, Veronica A

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C2.2 Postzygotic activating variants in mapk pathway genes cause intracranial and extracranial vascular malformations that respond to targeted inhibition by Al-Olabi, Lara, Polubothu, Satyamaanasa, Dowsett, Katherine, Andrews, Katrina A, Stadnik, Paulina, Joseph, Agnel P, Knox, Rachel, Pittman, Alan, Clark, Graeme, Baird, William, Bulstrode, Neil, Glover, Mary, Gordon, Kristiana, Hargrave, Darren, Huson, Susan M, Jacques, Thomas, James, Gregory, Kondolf, Hannah, Kangesu, Loshan, Keppler-Noreuil, Kim M, Khan, Amjad, Lindhurst, Marjorie J, Lipson, Mark, Mansour, Sahar, O’Hara, Justine, Mahon, Caroline, Mosica, Anda, Moss, Celia, Murthy, Aditi, Ong, Juling, Parker, Victoria, Rivière, Jean-Baptiste, Sapp, Julie C, Sebire, Neil J, Shah, Rahul, Sivakumar, Bran, Thomas, Anna, Virasami, Alex, Waelchli, Regula, Zeng, Zhiqiang, Biesecker, Leslie G, Barnacle, Alex, Topf, Maja, Semple, Robert, Patton, E Elizabeth, Kinsler, Veronica A

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