Loss of TET2 in hematopoietic cells leads to DNA hypermethylation of active enhancers and induction of leukemogenesis by Rasmussen, Kasper D, Jia, Guangshuai, Johansen, Jens V, Pedersen, Marianne T, Rapin, Nicolas, Bagger, Frederik O, Porse, Bo T, Bernard, Olivier A, Christensen, Jesper, Helin, Kristian

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TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells by Rasmussen, Kasper D, Berest, Ivan, Keβler, Sandra, Nishimura, Koutarou, Simón-Carrasco, Lucía, Vassiliou, George S, Pedersen, Marianne T, Christensen, Jesper, Zaugg, Judith B, Helin, Kristian

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Genome-wide profiling identifies a DNA methylation signature that associates with TET2 mutations in diffuse large B-cell lymphoma by Asmar, Fazila, Punj, Vasu, Christensen, Jesper, Pedersen, Marianne T, Pedersen, Anja, Nielsen, Anders B, Hother, Christoffer, Ralfkiaer, Ulrik, Brown, Peter, Ralfkiaer, Elisabeth, Helin, Kristian, Grønbæk, Kirsten

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Molecular Regulation of MHC Class I Chain-Related Protein A Expression after HDAC-Inhibitor Treatment of Jurkat T Cells by Andresen, Lars, Jensen, Helle, Pedersen, Marianne T, Hansen, Karen A, Skov, Soren

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Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders by Tucker-Drob, Elliot M., Yu, Dongmei, Ge, Tian, Derks, Eske M., Keski-Rahkonen, Anna, Kirov, George, Asherson, Philip, Baldursson, Gísli, Bybjerg-Grauholm, Jonas, Churchhouse, Claire, Crosbie, Jennifer, Demontis, Ditte, Grove, Jakob, Martin, Joanna, McGough, James J., Pedersen, Carsten B., Poulsen, Jesper B., Rothenberger, Aribert, Schachar, Russell, Turley, Patrick, Arking, Dan E., Collins, Ryan L., Coon, Hilary, Delorme, Richard, Hope, Sigrun, Nyegaard, Mette, Pinto, Dalila, Qvist, Per, Talkowski, Michael E., Albani, Diego, Alda, Martin, Bass, Nicholas, Bauer, Michael, Cichon, Sven, Clarke, Toni-Kim, Czerski, Piotr M., Fischer, Sascha B., Frank, Josef, Goes, Fernando S., Holland, Dominic, Jones, Lisa A., Joachim, Oedegaard Ketil, Maaser, Anna, Malt, Ulrik F., McMahon, Francis J., Montgomery, Grant W., Myers, Richard M., Nöthen, Markus M., Perry, Amy, Vieta, Eduard, Aschauer, Harald, Bencko, Vladimir, Burghardt, Roland, Carlberg, Laura, Guo, Yiran, Klump, Kelly L., Le Hellard, Stephanie, Monteleone, Alessio Maria, Seitz, Jochen, Treasure, Janet, Wade, Tracey D., Wichmann, H-Erich, Woodside, D. Blake, Grabe, Hans J., Horn, Carsten, Penninx, Brenda WJH, Schulte, Eva C., Smith, Daniel J., Alexander, Madeline, Begemann, Martin, Campion, Dominique, Ehrenreich, Hannelore, Murphy, Kieran C., Riley, Brien, Sham, Pak C., van Os, Jim, Weiser, Mark, Brown, Lawrence W., Cheon, Keun-Ah, Denys, Damiaan, Gilbert, Donald L., Grados, Marco A., Ibanez-Gomez, Laura, King, Robert A., Leventhal, Bennett L., Okun, Michael S., Piras, Federica, Robertson, Mary, Samuels, Jack F., Spalletta, Gianfranco, Stein, Dan J., Stewart, S Evelyn, Storch, Eric A., Stranger, Barbara, Tübing, Jennifer, Visscher, Frank, Wagner, Michael, Santangelo, Susan L., Thornton, Laura M., Neale, Benjamin M.

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Arimoclomol increases the transcription of lysosomal genes, including and , to facilitate lysosomal function by Petersen, Nikolaj H.T., Klein, Pontus, Valacca, Cristina, Bie, Anne, Magnoni, Raffaella, Pedersen, Marianne T., Lampp, Andrea C., Fog, Cathrine K., Kirkegaard, Thomas T.

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Arimoclomol increases the transcription of lysosomal genes, including NPC1 and NPC2, to facilitate lysosomal function by Petersen, Nikolaj H.T., Klein, Pontus, Valacca, Cristina, Bie, Anne, Magnoni, Raffaella, Pedersen, Marianne T., Lampp, Andrea C., Fog, Cathrine K., Kirkegaard, Thomas T.

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DNMT3AR882H mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice by Scourzic, L, Couronné, L, Pedersen, M T, Della Valle, V, Diop, M, Mylonas, E, Calvo, J, Mouly, E, Lopez, C K, Martin, N, Fontenay, M, Bender, A, Guibert, S, Dubreuil, P, Dessen, P, Droin, N, Pflumio, F, Weber, M, Gaulard, P, Helin, K, Mercher, T, Bernard, O A

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Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap by Gandal, Michael J, Haney, Jillian R, Parikshak, Neelroop N, Leppa, Virpi, Ramaswami, Gokul, Hartl, Chris, Schork, Andrew J, Appadurai, Vivek, Buil, Alfonso, Werge, Thomas M, Liu, Chunyu, White, Kevin P, Horvath, Steve, Geschwind, Daniel H

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Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank by Coleman, Jonathan R. I., Peyrot, Wouter J., Purves, Kirstin L., Davis, Katrina A. S., Rayner, Christopher, Choi, Shing Wan, Hübel, Christopher, Gaspar, Héléna A., Kan, Carol, Van der Auwera, Sandra, Adams, Mark James, Lyall, Donald M., Choi, Karmel W., Dunn, Erin C., Vassos, Evangelos, Danese, Andrea, Maughan, Barbara, Grabe, Hans J., Lewis, Cathryn M., O’Reilly, Paul F., McIntosh, Andrew M., Smith, Daniel J., Wray, Naomi R., Hotopf, Matthew, Eley, Thalia C., Breen, Gerome

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Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia by The Psychiatric Genomics Consortium, The Autism Spectrum Disorders Working Group Of, Anney, Richard J L, Ripke, Stephan, Anttila, Verneri, Grove, Jakob, Holmans, Peter, Huang, Hailiang, Klei, Lambertus, Lee, Phil H, Medland, Sarah E, Neale, Benjamin, Robinson, Elise, Weiss, Lauren A, Zwaigenbaum, Lonnie, Yu, Timothy W, Wittemeyer, Kerstin, Willsey, a Jeremy, Wijsman, Ellen M, Werge, Thomas, Wassink, Thomas H, Waltes, Regina, Walsh, Christopher A, Wallace, Simon, Vorstman, Jacob a S, Vieland, Veronica J, Vicente, Astrid M, Vanengeland, Herman, Tsang, Kathryn, Thompson, Ann P, Szatmari, Peter, Svantesson, Oscar, Steinberg, Stacy, Stefansson, Kari, Stefansson, Hreinn, State, Matthew W, Soorya, Latha, Silagadze, Teimuraz, Scherer, Stephen W, Schellenberg, Gerard D, Sandin, Sven, Sanders, Stephan J, Saemundsen, Evald, Rouleau, Guy A, Rogé, Bernadette, Roeder, Kathryn, Roberts, Wendy, Reichert, Jennifer, Reichenberg, Abraham, Rehnström, Karola, Regan, Regina, Poustka, Fritz, Poultney, Christopher S, Piven, Joseph, Pinto, Dalila, Pericak-Vance, Margaret A, Pejovic-Milovancevic, Milica, Pedersen, Marianne Giørtz, Pedersen, Carsten Bøcker, Paterson, Andrew D, Parr, Jeremy R, Pagnamenta, Alistair T, Oliveira, Guiomar, Nurnberger, John I, Nordentoft, Merete, Murtha, Michael T, Mouga, Susana, Mortensen, Preben Bo, Mors, Ole, Morrow, Eric M, Moreno-De-Luca, Daniel, Monaco, Anthony P, Minshew, Nancy, Merikangas, Alison, Mcmahon, William M, Mcgrew, Susan G, Mattheisen, Manuel, Martsenkovsky, Igor, Martin, Donna M, Mane, Shrikant M, Magnusson, Pall, Magalhaes, Tiago, Maestrini, Elena, Lowe, Jennifer K, Lord, Catherine, Levitt, Pat, Martin, Christa Lese, Ledbetter, David H, Leboyer, Marion, Lecouteur, Ann S, Ladd-Acosta, Christine, Kolevzon, Alexander, Klauck, Sabine M, Jacob, Suma, Iliadou, Bozenna, Hultman, Christina M, Hougaard, David M, Hertz-Picciotto, Irva, Hendren, Robert, Hansen, Christine Søholm, Haines, Jonathan L

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Elevated polygenic burden for autism is associated with differential DNA methylation at birth by Hannon, Eilis, Schendel, Diana, Ladd-Acosta, Christine, Grove, Jakob, Hansen, Christine Søholm, Andrews, Shan V, Hougaard, David Michael, Bresnahan, Michaeline, Mors, Ole, Hollegaard, Mads Vilhelm, Bækvad-Hansen, Marie, Hornig, Mady, Mortensen, Preben Bo, Børglum, Anders D, Werge, Thomas, Pedersen, Marianne Giørtz, Nordentoft, Merete, Buxbaum, Joseph, Daniele Fallin, M, Bybjerg-Grauholm, Jonas, Reichenberg, Abraham, Mill, Jonathan

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Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns by Czamara, Darina, Eraslan, Gökçen, Page, Christian M., Lahti, Jari, Lahti-Pulkkinen, Marius, Hämäläinen, Esa, Kajantie, Eero, Laivuori, Hannele, Villa, Pia M., Reynolds, Rebecca M., Nystad, Wenche, Håberg, Siri E., London, Stephanie J., O’Donnell, Kieran J., Garg, Elika, Meaney, Michael J., Entringer, Sonja, Wadhwa, Pathik D., Buss, Claudia, Jones, Meaghan J., Lin, David T. S., MacIsaac, Julie L., Kobor, Michael S., Koen, Nastassja, Zar, Heather J., Koenen, Karestan C., Dalvie, Shareefa, Stein, Dan J., Kondofersky, Ivan, Müller, Nikola S., Theis, Fabian J., Räikkönen, Katri, Binder, Elisabeth B.

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A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank by Shen, Xueyi, Howard, David M., Adams, Mark J., Hill, W. David, Clarke, Toni-Kim, Deary, Ian J., Whalley, Heather C., McIntosh, Andrew M.

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Association of polygenic score for major depression with response to lithium in patients with bipolar disorder by Amare, Azmeraw T., Schubert, Klaus Oliver, Clark, Scott R., Papiol, Sergi, Cearns, Micah, Heilbronner, Urs, Degenhardt, Franziska, Tekola-Ayele, Fasil, Hsu, Yi-Hsiang, Shekhtman, Tatyana, Adli, Mazda, Akula, Nirmala, Akiyama, Kazufumi, Ardau, Raffaella, Arias, Bárbara, Aubry, Jean-Michel, Backlund, Lena, Bhattacharjee, Abesh Kumar, Bellivier, Frank, Bengesser, Susanne, Biernacka, Joanna M., Birner, Armin, Brichant-Petitjean, Clara, Cervantes, Pablo, Chen, Hsi-Chung, Chillotti, Caterina, Cichon, Sven, Cruceanu, Cristiana, Czerski, Piotr M., Dalkner, Nina, Del Zompo, Maria, DePaulo, J. Raymond, Étain, Bruno, Jamain, Stephane, Falkai, Peter, Forstner, Andreas J., Frisen, Louise, Frye, Mark A., Fullerton, Janice M., Gard, Sébastien, Garnham, Julie S., Goes, Fernando S., Grof, Paul, Hashimoto, Ryota, Hauser, Joanna, Herms, Stefan, Hoffmann, Per, Hofmann, Andrea, Jiménez, Esther, Kahn, Jean-Pierre, Kassem, Layla, Kuo, Po-Hsiu, Kato, Tadafumi, Kelsoe, John R., Kliwicki, Sebastian, König, Barbara, Landén, Mikael, Lavebratt, Catharina, Leboyer, Marion, Leckband, Susan G., Tortorella, Alfonso, Martinsson, Lina, McCarthy, Michael J., McElroy, Susan L., Colom, Francesc, Mitjans, Marina, Mondimore, Francis M., Monteleone, Palmiero, Nievergelt, Caroline M., Nöthen, Markus M., Novák, Tomas, Ozaki, Norio, Pfennig, Andrea, Potash, James B., Reif, Andreas, Reininghaus, Eva, Rybakowski, Janusz K., Schofield, Peter R., Schweizer, Barbara W., Severino, Giovanni, Shilling, Paul D., Shimoda, Katzutaka, Simhandl, Christian, Slaney, Claire M., Squassina, Alessio, Stamm, Thomas, Stopkova, Pavla, Maj, Mario, Turecki, Gustavo, Vieta, Eduard, Veeh, Julia, Witt, Stephanie H., Wright, Adam, Zandi, Peter P., Mitchell, Philip B., Bauer, Michael, Alda, Martin, Rietschel, Marcella, Schulze, Thomas G., Baune, Bernhard T.

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Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium by Peyrot, Wouter J., Milaneschi, Yuri, Madden, Pamela A.F., Ripke, Stephan, Mullins, Niamh, Heat, Andrew C., Fisher, Helen L., Byrne, Enda M., Air, Tracy A., Wray, Naomi R., Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Air, Tracy M., Blackwood, Douglas H.R., Bryois, Julien, Bybjerg-Grauholm, Jonas, Cai, Na, Clarke, Toni-Kim, Crawford, Gregory E., Dolan, Conor V., Escott-Price, Valentina, Farnush, Kiadeh, Farhadi Hassan, Finucane, Hilary K., Forstner, Andreas J., Frank, Josef, Hansen, Thomas F., Herms, Stefan, Hicki, Ian B., Hoffmann, Per, Homuth, Georg, Horn, Carsten, Hottenga, Jouke-Jan, Hougaard, David M., Ising, Marcus, Jansen, Rick, Jorgenson, Eric, Kohane, Isaac S., Kretzschmar, Warren W., Li, Yihan, MacKinnon, Dean F., Maier, Wolfgang, Marchini, Jonathan, Mbarek, Hamdi, McGuffin, Peter, Medland, Sarah E., Mehta, Divya, Middeldorp, Christel M., Mihailov, Evelin, Mondimore, Francis M., Mullins, Niamh, Nauck, Matthias, Nyholt, Dale R., Oskarsson, Hogni, Painter, Jodie N., Pedersen, Marianne Giørtz, Peterson, Roseann E., Pistis, Giorgio, Qvist, Per, Rice, John P., Rivera, Margarita, Shen, Ling, Shi, Jianxin, Smit, Johannes H., Steinberg, Stacy, Strohmaier, Jana, Teumer, Alexander, Thorgeirsson, Thorgeir E., Trubetskoy, Vassily, Uitterlinden, André G., van Hemert, Albert M., Wang, Yunpeng, Webb, Bradley T., Weinsheimer, Shantel Marie, Wu, Yang, Xi, Hualin S., Yang, Jian, Arolt, Volker, de Geus, E.J.C., Hamilton, Steven P., Hayward, Caroline, Kendler, Kenneth S., Madden, Pamela A.F., Magnusson, Patrik K., Metspalu, Andres, Nöthen, Markus M., Penninx, Brenda W.J.H., Schaefer, Catherine, Schulze, Thomas G., Uher, Rudolf, Werge, Thomas, Lewis, Cathryn M., Levinson, Douglas F., Breen, Gerome, Børglum, Anders D., Sullivan, Patrick F., Breen, Gerome, Martin, Nick G., Grabe, Hans J.

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Genome-wide association study of school grades identifies genetic overlap between language ability, psychopathology and creativity by Rajagopal, Veera M., Ganna, Andrea, Coleman, Jonathan R. I., Allegrini, Andrea, Voloudakis, Georgios, Grove, Jakob, Als, Thomas D., Horsdal, Henriette T., Petersen, Liselotte, Appadurai, Vivek, Schork, Andrew, Buil, Alfonso, Bulik, Cynthia M., Bybjerg-Grauholm, Jonas, Bækvad-Hansen, Marie, Hougaard, David M., Mors, Ole, Nordentoft, Merete, Werge, Thomas, Mortensen, Preben Bo, Breen, Gerome, Roussos, Panos, Plomin, Robert, Agerbo, Esben, Børglum, Anders D., Demontis, Ditte

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Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders by Andlauer, Till F. M., Guzman-Parra, Jose, Streit, Fabian, Strohmaier, Jana, González, Maria José, Gil Flores, Susana, Cabaleiro Fabeiro, Francisco J., del Río Noriega, Francisco, Perez, Fermin Perez, Haro González, Jesus, Orozco Diaz, Guillermo, de Diego-Otero, Yolanda, Moreno-Küstner, Berta, Auburger, Georg, Degenhardt, Franziska, Heilmann-Heimbach, Stefanie, Herms, Stefan, Hoffmann, Per, Frank, Josef, Foo, Jerome C., Treutlein, Jens, Witt, Stephanie H., Cichon, Sven, Kogevinas, Manolis, Rivas, Fabio, Mayoral, Fermín, Müller-Myhsok, Bertram, Forstner, Andreas J., Nöthen, Markus M., Rietschel, Marcella

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Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression by Hanscombe, Ken B., Euesden, Jack, Choi, Shing Wan, Binder, Elisabeth B., Blackwood, Douglas H.R., Colodro-Conde, Lucía, Dannlowski, Udo, Dunn, Erin C., de Geus, Eco J.C., Grabe, Hans J., Jones, Ian, Knowles, James A., Kutalik, Zoltán, Müller-Myhsok, Bertram, Penninx, Brenda W.J.H., Shyn, Stanley I., Sullivan, Patrick F., Tiemeier, Henning, Weissman, Myrna M., Ripke, Stephan, Byrne, Enda M., Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Castelao, Enrique, Christensen, Jane Hvarregaard, Couvy-Duchesne, Baptiste, Craddock, Nick, Davies, Gail, Derks, Eske M., Dolan, Conor V., Eley, Thalia C., Gaspar, Héléna A., Gill, Michael, Goes, Fernando S., Gordon, Scott D., Grove, Jakob, Hickie, Ian B., Hottenga, Jouke-Jan, Jansen, Rick, Jones, Ian, Jorgenson, Eric, Kraft, Julia, Li, Yihan, Lind, Penelope A., MacIntyre, Donald J., Mbarek, Hamdi, McGrath, Patrick, Mehta, Divya, Milaneschi, Yuri, Mullins, Niamh, Nivard, Michel G., Nyholt, Dale R., O'Reilly, Paul F., Oskarsson, Hogni, Pedersen, Carsten Bøcker, Pedersen, Marianne Giørtz, Peterson, Roseann E., Pistis, Giorgio, Rivera, Margarita, Mirza, Saira Saeed, Schoevers, Robert, Schulte, Eva C., Shen, Ling, Shi, Jianxin, Sinnamon, Grant C.B., Smit, Johannes H., Steinberg, Stacy, Tansey, Katherine E., Teumer, Alexander, Van der Auwera, Sandra, Wang, Yunpeng, Weinsheimer, Shantel Marie, Willemsen, Gonneke, Wu, Yang, Yang, Jian, de Geus, EJC, DePaulo, J. Raymond, Esko, Tõnu, Grabe, Hans J., Hamilton, Steven P., Hayward, Caroline, Heath, Andrew C., Kendler, Kenneth S., Lewis, Glyn, Magnusson, Patrik K., Nordentoft, Merete, Pedersen, Nancy L., Penninx, Brenda W.J.H., Porteous, David J., Potash, James B., Schaefer, Catherine, Tiemeier, Henning, Werge, Thomas, Levinson, Douglas F., Breen, Gerome, Sullivan, Patrick F., O'Reilly, Paul F., Lewis, Cathryn M.

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TET Proteins and Histone Modifications in Hematopoiesis by Helin, Kristian, Rasmusssen, Kasper D., Pedersen, Marianne T., Jia, Guangshuai, Williams, Kristine, Johansen, Jens V., Cloos, Paul A.C., Bernard, Olivier A., Christensen, Jesper

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