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Search Results - Perlow-Poehnelt, Rebecca A
Search Results - Perlow-Poehnelt, Rebecca A
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Substrate Discrimination by Formamidopyrimidine-DNA Glycosylase: Distinguishing Interactions within the Active Site
by
Perlow-Poehnelt, Rebecca A
,
Zharkov, Dmitry O
,
Grollman, Arthur P
,
Broyde, Suse
Published in
Biochemistry (Easton)
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The spacious active site of a Y-family DNA polymerase facilitates promiscuous nucleotide incorporation opposite a bulky carcinogen-DNA adduct: elucidating the structure-function re...
by
Perlow-Poehnelt, Rebecca A
,
Likhterov, Ilya
,
Scicchitano, David A
,
Geacintov, Nicholas E
,
Broyde, Suse
Published in
The Journal of biological chemistry
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Increased Flexibility Enhances Misincorporation: TEMPERATURE EFFECTS ON NUCLEOTIDE INCORPORATION OPPOSITE A BULKY CARCINOGEN-DNA ADDUCT BY A Y-FAMILY DNA POLYMERASE
by
Perlow-Poehnelt, Rebecca A
,
Likhterov, Ilya
,
Wang, Lihua
,
Scicchitano, David A
,
Geacintov, Nicholas E
,
Broyde, Suse
Published in
The Journal of biological chemistry
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Increased Flexibility Enhances Misincorporation
by
Perlow-Poehnelt, Rebecca A.
,
Likhterov, Ilya
,
Wang, Lihua
,
Scicchitano, David A.
,
Geacintov, Nicholas E.
,
Broyde, Suse
Published in
The Journal of biological chemistry
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The Spacious Active Site of a Y-Family DNA Polymerase Facilitates Promiscuous Nucleotide Incorporation Opposite a Bulky Carcinogen-DNA Adduct
by
Perlow-Poehnelt, Rebecca A.
,
Likhterov, Ilya
,
Scicchitano, David A.
,
Geacintov, Nicholas E.
,
Broyde, Suse
Published in
The Journal of biological chemistry
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Biaryl ethers as potent allosteric inhibitors of reverse transcriptase and its key mutant viruses: Aryl substituted pyrazole as a surrogate for the pyrazolopyridine motif
by
Su, Dai-Shi
,
Lim, John J.
,
Tinney, Elizabeth
,
Tucker, Thomas J.
,
Saggar, Sandeep
,
Sisko, John T.
,
Wan, Bang-Lin
,
Young, Mary Beth
,
Anderson, Kenneth D.
,
Rudd, Deanne
,
Munshi, Vandna
,
Bahnck, Carolyn
,
Felock, Peter J.
,
Lu, Meiquing
,
Lai, Ming-Tain
,
Touch, Sinoeun
,
Moyer, Gregory
,
DiStefano, Daniel J.
,
Flynn, Jessica A.
,
Liang, Yuexia
,
Sanchez, Rosa
,
Perlow-Poehnelt, Rebecca
,
Miller, Mike
,
Vacca, Joe P.
,
Williams, Theresa M.
,
Anthony, Neville J.
Published in
Bioorganic & medicinal chemistry letters
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Discovery of 3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): A Potent, Orally Bioavailable HIV-1 Non-Nucleoside Reverse Tra...
by
Tucker, Thomas J
,
Sisko, John T
,
Tynebor, Robert M
,
Williams, Theresa M
,
Felock, Peter J
,
Flynn, Jessica A
,
Lai, Ming-Tain
,
Liang, Yuexia
,
McGaughey, Georgia
,
Liu, Meiquing
,
Miller, Mike
,
Moyer, Gregory
,
Munshi, Vandna
,
Perlow-Poehnelt, Rebecca
,
Prasad, Sridhar
,
Reid, John C
,
Sanchez, Rosa
,
Torrent, Maricel
,
Vacca, Joseph P
,
Wan, Bang-Lin
,
Yan, Youwei
Published in
Journal of medicinal chemistry
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Biaryl Ethers as Novel Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Key Mutant Viruses
by
Su, Dai-Shi
,
Lim, John J
,
Tinney, Elizabeth
,
Wan, Bang-Lin
,
Young, Mary Beth
,
Anderson, Kenneth D
,
Rudd, Deanne
,
Munshi, Vandna
,
Bahnck, Carolyn
,
Felock, Peter J
,
Lu, Meiquing
,
Lai, Ming-Tain
,
Touch, Sinoeun
,
Moyer, Gregory
,
DiStefano, Daniel J
,
Flynn, Jessica A
,
Liang, Yuexia
,
Sanchez, Rosa
,
Perlow-Poehnelt, Rebecca
,
Miller, Mike
,
Vacca, Joe P
,
Williams, Theresa M
,
Anthony, Neville J
Published in
Journal of medicinal chemistry
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The design and synthesis of diaryl ether second generation HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) with enhanced potency versus key clinical mutations
by
Tucker, Thomas J.
,
Saggar, Sandeep
,
Sisko, John T.
,
Tynebor, Robert M.
,
Williams, Theresa M.
,
Felock, Peter J.
,
Flynn, Jessica A.
,
Lai, Ming-Tain
,
Liang, Yuexia
,
McGaughey, Georgia
,
Liu, Meiquing
,
Miller, Mike
,
Moyer, Gregory
,
Munshi, Vandna
,
Perlow-Poehnelt, Rebecca
,
Prasad, Sridhar
,
Sanchez, Rosa
,
Torrent, Maricel
,
Vacca, Joseph P.
,
Wan, Bang-Lin
,
Yan, Youwei
Published in
Bioorganic & medicinal chemistry
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10
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Substituted tetrahydroquinolines as potent allosteric inhibitors of reverse transcriptase and its key mutants
by
Su, Dai-Shi
,
Lim, John J.
,
Tinney, Elizabeth
,
Wan, Bang-Lin
,
Young, Mary Beth
,
Anderson, Kenneth D.
,
Rudd, Deanne
,
Munshi, Vandna
,
Bahnck, Carolyn
,
Felock, Peter J.
,
Lu, Meiqing
,
Lai, Ming-Tain
,
Touch, Sinoeun
,
Moyer, Gregory
,
DiStefano, Daniel J.
,
Flynn, Jessica A.
,
Liang, Yuexia
,
Sanchez, Rosa
,
Prasad, Sridhar
,
Yan, Youwei
,
Perlow-Poehnelt, Rebecca
,
Torrent, Maricel
,
Miller, Mike
,
Vacca, Joe P.
,
Williams, Theresa M.
,
Anthony, Neville J.
Published in
Bioorganic & medicinal chemistry letters
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