Bispecific antibody target pair discovery by high-throughput phenotypic screening using in vitro combinatorial Fab libraries by Bhatta, Pallavi, Whale, Kevin D, Sawtell, Amy K, Thompson, Clare L, Rapecki, Stephen E, Cook, David A, Twomey, Breda M, Mennecozzi, Milena, Starkie, Laura E, Barry, Emily M C, Peters, Shirley J, Kamal, Ahmad M, Finney, Helene M

Get full text

On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation by Sopp, Joshua M., Peters, Shirley J., Rowley, Tania F., Oldham, Robert J., James, Sonya, Mockridge, Ian, French, Ruth R., Turner, Alison, Beers, Stephen A., Humphreys, David P., Cragg, Mark S.

Get full text

Molecular Insights into the Thermal Stability of mAbs with Variable-Temperature Ion-Mobility Mass Spectrometry by Pacholarz, Kamila J., Peters, Shirley J., Garlish, Rachel A., Henry, Alistair J., Taylor, Richard J., Humphreys, David P., Barran, Perdita E.

Get full text

Engineering an Improved IgG4 Molecule with Reduced Disulfide Bond Heterogeneity and Increased Fab Domain Thermal Stability by Peters, Shirley J., Smales, C. Mark, Henry, Alistair J., Stephens, Paul E., West, Shauna, Humphreys, David P.

Get full text

Engineered hexavalent Fc proteins with enhanced Fc-gamma receptor avidity provide insights into immune-complex interactions by Rowley, Tania F., Peters, Shirley J., Aylott, Mike, Griffin, Robert, Davies, Nicola L., Healy, Louise J., Cutler, Rona M., Eddleston, Alison, Pither, Thomas L., Sopp, Joshua M., Zaccheo, Oliver, Fossati, Gianluca, Cain, Katharine, Ventom, Andrew M., Hailu, Hanna, Ward, Eleanor J., Sherington, John, Brennan, Frank R., Fallah-Arani, Farnaz, Humphreys, David P.

Get full text

Bispecific antibody target pair discovery by high-throughput phenotypic screening using in vitro combinatorial Fab libraries by Bhatta, Pallavi, Whale, Kevin D., Sawtell, Amy K., Thompson, Clare L., Rapecki, Stephen E., Cook, David A., Twomey, Breda M., Mennecozzi, Milena, Starkie, Laura E., Barry, Emily M. C., Peters, Shirley J., Kamal, Ahmad M., Finney, Helene M.

Get full text

The Effect of a New Multimodal Perioperative Anesthetic Regimen on Postoperative Pain, Side Effects, Rehabilitation, and Length of Hospital Stay After Total Joint Arthroplasty by Peters, Christopher L., Shirley, Brayton, Erickson, Jill

Get full text

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms by Gordon, David E, Hiatt, Joseph, Bouhaddou, Mehdi, Rezelj, Veronica V, Ulferts, Svenja, Braberg, Hannes, Jureka, Alexander S, Obernier, Kirsten, Guo, Jeffrey Z, Batra, Jyoti, Kaake, Robyn M, Weckstein, Andrew R, Owens, Tristan W, Gupta, Meghna, Pourmal, Sergei, Titus, Erron W, Cakir, Merve, Soucheray, Margaret, McGregor, Michael, Cakir, Zeynep, Jang, Gwendolyn, O'Meara, Matthew J, Tummino, Tia A, Zhang, Ziyang, Foussard, Helene, Rojc, Ajda, Zhou, Yuan, Kuchenov, Dmitry, Hüttenhain, Ruth, Xu, Jiewei, Eckhardt, Manon, Swaney, Danielle L, Fabius, Jacqueline M, Ummadi, Manisha, Tutuncuoglu, Beril, Rathore, Ujjwal, Modak, Maya, Haas, Paige, Haas, Kelsey M, Naing, Zun Zar Chi, Pulido, Ernst H, Shi, Ying, Barrio-Hernandez, Inigo, Memon, Danish, Petsalaki, Eirini, Dunham, Alistair, Marrero, Miguel Correa, Burke, David, Koh, Cassandra, Vallet, Thomas, Silvas, Jesus A, Azumaya, Caleigh M, Billesbølle, Christian, Brilot, Axel F, Campbell, Melody G, Diallo, Amy, Dickinson, Miles Sasha, Diwanji, Devan, Herrera, Nadia, Hoppe, Nick, Kratochvil, Huong T, Liu, Yanxin, Merz, Gregory E, Moritz, Michelle, Nguyen, Henry C, Nowotny, Carlos, Puchades, Cristina, Rizo, Alexandrea N, Schulze-Gahmen, Ursula, Smith, Amber M, Sun, Ming, Young, Iris D, Zhao, Jianhua, Asarnow, Daniel, Biel, Justin, Bowen, Alisa, Braxton, Julian R, Chen, Jen, Chio, Cynthia M, Chio, Un Seng, Deshpande, Ishan, Doan, Loan, Faust, Bryan, Flores, Sebastian, Jin, Mingliang, Kim, Kate, Lam, Victor L, Li, Fei, Li, Junrui, Li, Yen-Li, Li, Yang, Liu, Xi, Lo, Megan, Lopez, Kyle E, Melo, Arthur A, Moss, 3rd, Frank R, Nguyen, Phuong, Paulino, Joana, Pawar, Komal Ishwar, Peters, Jessica K

Request full text

Pathological Computed Tomography Features Associated With Adverse Outcomes After Mild Traumatic Brain Injury: A TRACK-TBI Study With External Validation in CENTER-TBI by Yuh, Esther, Jain, Sonia, Sun, Xiaoying, Pisică, Dana, Harris, Mark H, Taylor, Sabrina R, Markowitz, Amy J, Mukherjee, Pratik, Verheyden, Jan, Giacino, Joseph T, Levin, Harvey, McCrea, Michael, Stein, Murray B, Temkin, Nancy R, Diaz-Arrastia, Ramon, Robertson, Claudia, Lingsma, Hester F, Okonkwo, David O, Maas, Andrew I. R, Manley, Geoffrey T, Andelic, Nada, Andreassen, Lasse, Anke, Audny Gabriele Wagner, Frisvold, Shirin, Helseth, Eirik, Røe, Cecilie, Røise, Olav, Skandsen, Toril, Vik, Anne, Åkerlund, Cecilia, Amrein, Krisztina, Antoni, Anna, Audibert, Gerard, Azouvi, Philippe, Azzolini, Maria luisa, Bartels, Ronald, Barzo, Pal, Beauvais, Romuald, Beer, Ronny, Bellander, Bo-michael, Belli, Antonio, Benali, Habib, Berardino, Maurizio, Beretta, Luigi, Blaabjerg, Morten, Bragge, Peter, Brazinova, Alexandra, Brinck, Vibeke, Brooker, Joanne, Brorsson, Camilla, Buki, Andras, Bullinger, Monika, Cabeleira, Manuel, Caccioppola, Alessio, Calappi, Emiliana, Calvi, Maria rosa

Request full text

High bias gas flows increase lung injury in the ventilated preterm lamb by Bach, Katinka P, Kuschel, Carl A, Hooper, Stuart B, Bertram, Jean, McKnight, Sue, Peachey, Shirley E, Zahra, Valerie A, Flecknoe, Sharon J, Oliver, Mark H, Wallace, Megan J, Bloomfield, Frank H

Get full text

An integrated encyclopedia of DNA elements in the human genome by Kundaje, Anshul, Collins, Patrick J, Davis, Carrie A, Khatun, Jainab, Lajoie, Bryan R, Landt, Stephen G, Safi, Alexias, Altshuler, Robert C, Cheng, Chao, Greven, Melissa, Hoffman, Michael M, Lassmann, Timo, Thurman, Robert E, Wu, Weisheng, Xi, Hualin S, Zhuang, Jiali, Gunter, Chris, Dekker, Job, Elnitski, Laura, Giddings, Morgan C, Margulies, Elliott H, Stamatoyannopoulos, John A, Wold, Barbara, Kuiper, Heather C, Dobin, Alex, Tanzer, Andrea, Xue, Chenghai, Zaleski, Chris, Roder, Maik, Baer, Michael T, Bell, Kimberly, Gordon, Assaf, Howald, Cedric, Johnson, Rory, Kingswood, Colin, Li, Guoliang, Luo, Oscar J, Robyr, Daniel, Ruan, Xiaoan, Skancke, Jorgen, Suzuki, Ana Maria, Takahashi, Hazuki, Tilgner, Hagen, Wang, Huaien, Hayashizaki, Yoshihide, Hannon, Gregory J, Malladi, Venkat S, Dreszer, Timothy R, Showers, Kimberly A, London, Darin, Zhang, Zhancheng, Keefe, Damian, Zheng, Meizhen, Vielmetter, Jost, Jain, Preti, Pusey, Barbara, Meadows, Sarah K, Absher, Devin M, Pennachio, Len A, Abyzov, Alexej, Barrell, Daniel, Bignell, Alexandra, Diekhans, Mark, Ezkurdia, Iakes, Frankish, Adam, Hunt, Toby, Jungreis, Irwin, Loveland, Jane, Manthravadi, Deepa, Pei, Baikang, Snow, Catherine, Zhang, Zhengdong, Alexander, Roger P, Balasubramanian, Suganthi, Bettinger, Keith, Cayting, Philip, Habegger, Lukas, Lamarre-Vincent, Nathan, Lindahl-Allen, Marianne, Monahan, Hannah, Patacsil, Dorrelyn, Struhl, Kevin, Ma, Lijia, Inoue, Daigo, Kellner, Tanja, Kirchmaier, Stephan, Bates, Daniel L, Canfield, Theresa K, Boatman, Lisa, Neph, Shane J, Roach, Vaughn, Sanchez, Minerva E, Shafer, Anthony O, Vernot, Benjamin, Weaver, Molly A, Akey, Joshua M, Bender, Michael, Navas, Patrick, Hussami, Nadine, Schaub, Marc A

Get full text

Defining the Newborn Blood Spot Screening Reference Interval for TSH: Impact of Ethnicity by Peters, Catherine, Brooke, Ivan, Heales, Simon, Ifederu, Adeboye, Langham, Shirley, Hindmarsh, Peter, Cole, Tim J

Get full text

Fluid balance and outcome in critically ill patients with traumatic brain injury (CENTER-TBI and OzENTER-TBI): a prospective, multicentre, comparative effectiveness study by Frisvold, Shirin, Menon, David Krishna, Moore, Elizabeth Madeleine, Steyerberg, Ewout Willem, van der Jagt, Mathieu, Cooper, Jamie D., Schoechl, Herbert, Van Praag, Dominique, Maas, Andrew I.R., Vande Vyvere, Thijs, Depreitere, Bart, Van Hecke, Wim, Ghuysen, Alexandre, Gao, Guoyi, Jiang, Ji-yao, Fabricius, Martin, Raj, Rahul, Pirinen, Matti, Audibert, Gérard, Degos, Vincent, Benali, Habib, Galanaud, Damien, Legrand, Valerie, Dahyot-Fizelier, Claire, Kowark, Ana, Vajkoczy, Peter, Maegele, Marc, Gratz, Johannes, Bullinger, Monika, Younsi, Alexander, Sakowitz, Oliver, Melegh, Béla, Sorinola, Abayomi, Kovács, Noémi, Nyirádi, József, Amrein, Krisztina, Azzolini, Maria Luisa, Stocchetti, Nino, Carbonara, Marco, Citerio, Giuseppe, Chieregato, Arturo, Chevallard, Giorgio, Della Corte, Francesco, Rossi, Sandra, Tamosuitis, Tomas, Rocka, Saulius, Steyerberg, Ewout W., Kompanje, Erwin, Timmers, Marjolijn, Haitsma, Iain, van der Jagt, Mathieu, Voormolen, Daphne, Wiegers, Eveline, Polinder, Suzanne, Tibboel, Dick, van Wijk, Roel, van Dijck, Jeroen T.J.M., Schoonman, Guus, Te Ao, Braden, Andelic, Nada, Frisvold, Shirin, Vik, Anne, Ples, Horia, Vulekovic, Peter, Karan, Mladen, Golubovic, Jagoš, Taylor, Mark Steven, Majdan, Marek, Sahuquillo, Juan, Radoi, Andreea, Lanyon, Linda, George, Pradeep, Muraleedharan, Visakh, Ackerlund, Cecilia, Koskinen, Lars-Owe, Sundström, Nina, Manara, Alex, Coles, Jonathan, Stamatakis, Emmanuel, Williams, Guy, Ercole, Ari, Dixit, Abhishek, Newcombe, Virginia, McFadyen, Charles, Adams, Hadie, McMahon, Catherine, Rueckert, Daniel, Esser, Patrick, van Heugten, Caroline, Stanworth, Simon, Otesile, Olubukola, Lightfoot, Roger, Horton, Lindsay, Rosand, Jonathan, Wang, Kevin K.W., Yang, Zhihui, Gruen, Russell L., Cameron, Peter, Varma, Dinesh, Jordan, Andrea

Get full text

Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network by Stoll, Barbara J, Hansen, Nellie I, Bell, Edward F, Shankaran, Seetha, Laptook, Abbot R, Walsh, Michele C, Hale, Ellen C, Newman, Nancy S, Schibler, Kurt, Carlo, Waldemar A, Kennedy, Kathleen A, Poindexter, Brenda B, Finer, Neil N, Ehrenkranz, Richard A, Duara, Shahnaz, Sánchez, Pablo J, O'Shea, T Michael, Goldberg, Ronald N, Van Meurs, Krisa P, Faix, Roger G, Phelps, Dale L, Frantz, 3rd, Ivan D, Watterberg, Kristi L, Saha, Shampa, Das, Abhik, Higgins, Rosemary D

Get full text

Increased age, high body mass index and low HDL-C levels are related to an echolucent carotid intima-media: the METEOR study by Peters, S. A. E., Lind, L., Palmer, M. K., Grobbee, D. E., Crouse III, J. R, O'Leary, D. H., Evans, G. W., Raichlen, J., Bots, M. L., den Ruijter, H. M.

Get full text

Characterization of the association between 8q24 and colon cancer: gene-environment exploration and meta-analysis by Hutter, Carolyn M, Slattery, Martha L, Duggan, David J, Muehling, Jill, Curtin, Karen, Hsu, Li, Beresford, Shirley A A, Rajkovic, Aleksandar, Sarto, Gloria E, Marshall, James R, Hammad, Nazik, Wallace, Robert, Makar, Karen W, Prentice, Ross L, Caan, Bette J, Potter, John D, Peters, Ulrike

Get full text

Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study by Wiegers, Eveline, Sewalt, Charlie, De Keyser, Véronique, Kunzmann, Kevin, von Steinbüchel, Nicole, Wilson, Lindsay, Maas, Andrew I R, Ackerlund, Cecilia, Andelic, Nada, Auslands, Kaspars, Bartels, Ronald, Barzó, Pál, Bellander, Bo-Michael, Benali, Habib, Brazinova, Alexandra, Brorsson, Camilla, Caccioppola, Alessio, Carbonara, Marco, Castaño-León, Ana M, Chevallard, Giorgio, Chieregato, Arturo, Coles, Jonathan, Cooper, Jamie D, Correia, Marta, Depreitere, Bart, Dijkland, Simone, Đilvesi, Đula, Donoghue, Emma, Dulière, Guy-Loup, Esser, Patrick, Feigin, Valery L, Foks, Kelly, Frisvold, Shirin, Furmanov, Alex, Gagliardo, Pablo, Gantner, Dashiell, Glocker, Ben, Gomez, Pedro A, Gratz, Johannes, Gravesteijn, Benjamin, Grossi, Francesca, Haagsma, Juanita A., Haitsma, Iain, Helbok, Raimund, Helseth, Eirik, Huijben, Jilske, Jankowski, Stefan, Karan, Mladen, Kolias, Angelos G, Kompanje, Erwin, Kondziella, Daniel, Lagares, Alfonso, Lanyon, Linda, Lejeune, Aurelie, Levi, Leon, Lightfoot, Roger, Maegele, Marc, McMahon, Catherine, Muraleedharan, Visakh, Murray, Lynnette, Negru, Ancuta, Noirhomme, Quentin, Piippo-Karjalainen, Anna, Ples, Horia, Raj, Rahul, Real, Ruben, Rhodes, Jonathan, Roe, Cecilie, Rosand, Jonathan, Rosenthal, Guy, Rossi, Sandra, Rusnák, Martin, Sanchez-Porras, Renan, Schäfer, Nadine, Schoechl, Herbert, Schou, Rico Frederik, Schwendenwein, Elisabeth, Skandsen, Toril, Sorinola, Abayomi, Stewart, William, Synnot, Anneliese, Theadom, Alice, Thomas, Matt, Tibboel, Dick, Trapani, Tony, Van der Steen, Gregory, van Dijck, Jeroen T J M, Van Hecke, Wim, van Heugten, Caroline, van Wijk, Roel P J, Vande Vyvere, Thijs, Verheyden, Jan, Vulekovic, Petar, Williams, Guy, Wilson, Lindsay, Winzeck, Stefan, Younsi, Alexander, Zelinkova, Veronika, Ziverte, Agate, Zoerle, Tommaso

Get full text

Intramyocardial, Autologous CD34+ Cell Therapy for Refractory Angina by Losordo, Douglas W, Henry, Timothy D, Davidson, Charles, Sup Lee, Joon, Costa, Marco A, Bass, Theodore, Mendelsohn, Farrell, Fortuin, F David, Pepine, Carl J, Traverse, Jay H, Amrani, David, Ewenstein, Bruce M, Riedel, Norbert, Story, Kenneth, Barker, Kerry, Povsic, Thomas J, Harrington, Robert A, Schatz, Richard A

Get full text

Incidence, aetiology, and sequelae of viral meningitis in UK adults: a multicentre prospective observational cohort study by McGill, Fiona, Griffiths, Michael J, Bonnett, Laura J, Geretti, Anna Maria, Michael, Benedict D, Beeching, Nicholas J, McKee, David, Scarlett, Paula, Hart, Ian J, Mutton, Kenneth J, Jung, Agam, Adan, Guleed, Gummery, Alison, Sulaiman, Wan Aliaa Wan, Ennis, Katherine, Martin, Antony P, Haycox, Alan, Miller, Alastair, Solomon, Tom, Adedeji, Adekola, Katharine, Ajdukiewicz, David, Birkenhead, Thomas, Blanchard, Antony, Cadwgan, David, Chadwick, John, Cheesbrough, Richard, Cooke, John, Croall, Iain, Crossingham, James, Dunbar, Simon, Ellis, Camelia, Faris, Peter, Flegg, Clive, Graham, Katherine, Gray, Shirley, Hammersley, Kevin, Jones, Matthew, Jones, Ildiko, Kustos, Susan, Larkin, Karim, Mahawish, Sarah, Maxwell, Jane, Minton, Kavya, Mohandas, Martin, Mostert, Ed, Moran, Christopher, Murphy, Monika, Pasztor, Hassan, Paraiso, Nikhil, Premchand, Haris, Rathur, Mark, Roberts, Amy, Robinson, Andrew, Rosser, Stefan, Schumacher, Monty, Silverdale, Philip, Stanley, Neil, Todd, Alastair, Watt, Martin, Wiselka

Get full text

Occurrence and timing of withdrawal of life-sustaining measures in traumatic brain injury patients: a CENTER-TBI study by van Veen, Ernest, van der Jagt, Mathieu, Citerio, Giuseppe, Stocchetti, Nino, Gommers, Diederik, Burdorf, Alex, Menon, David K., Maas, Andrew I. R., Kompanje, Erwin J. O., Lingsma, Hester F.

Get full text