Control of human pancreatic beta cell kinome by glucagon‐like peptide‐1 receptor biased agonism by Xiao, Jiannan, El Eid, Liliane, Buenaventura, Teresa, Boutry, Raphaël, Bonnefond, Amélie, Jones, Ben, Rutter, Guy A., Froguel, Philippe, Tomas, Alejandra

Get full text

Neonatal hyperglycaemia and abnormal development of the pancreas by Flechtner, Isabelle, MD, MSc, Vaxillaire, Martine, Dpharm, PhD, Cavé, Hélène, Dpharm, PhD, Scharfmann, Raphael, PhD, Froguel, Philippe, MD, PhD, Polak, Michel, MD, PhD

Get full text

High prevalence of leptin and melanocortin-4 receptor gene mutations in children with severe obesity from Pakistani consanguineous families by Saeed, Sadia, Butt, Taeed A., Anwer, Mehwish, Arslan, Muhammad, Froguel, Philippe

Get full text

Cloning of adiponectin receptors that mediate antidiabetic metabolic effects by YAMAUCHI, Toshimasa, KAMON, Junji, MURAKAMI, Koji, OHTEKI, Toshiaki, UCHIDA, Shoko, TAKEKAWA, Sato, WAKI, Hironori, TSUNO, Nelson H, SHIBATA, Yoichi, TERAUCHI, Yasuo, FROGUEL, Philippe, TOBE, Kazuyuki, ITO, Yusuke, KOYASU, Shigeo, TAIRA, Kazunari, KITAMURA, Toshio, SHIMIZU, Takao, NAGAI, Ryozo, KADOWAKI, Takashi, TSUCHIDA, Atsushi, YOKOMIZO, Takehiko, KITA, Shunbun, SUGIYAMA, Takuya, MIYAGISHI, Makoto, HARA, Kazuo, TSUNODA, Masaki

Get full text

Persistent or Transient Human β Cell Dysfunction Induced by Metabolic Stress: Specific Signatures and Shared Gene Expression with Type 2 Diabetes by Marselli, Lorella, Piron, Anthony, Suleiman, Mara, Colli, Maikel L., Yi, Xiaoyan, Khamis, Amna, Carrat, Gaelle R., Rutter, Guy A., Bugliani, Marco, Giusti, Laura, Ronci, Maurizio, Ibberson, Mark, Turatsinze, Jean-Valery, Boggi, Ugo, De Simone, Paolo, De Tata, Vincenzo, Lopes, Miguel, Nasteska, Daniela, De Luca, Carmela, Tesi, Marta, Bosi, Emanuele, Singh, Pratibha, Campani, Daniela, Schulte, Anke M., Solimena, Michele, Hecht, Peter, Rady, Brian, Bakaj, Ivona, Pocai, Alessandro, Norquay, Lisa, Thorens, Bernard, Canouil, Mickaël, Froguel, Philippe, Eizirik, Decio L., Cnop, Miriam, Marchetti, Piero

Get full text

Pathogenic monoallelic variants in GLIS3 increase type 2 diabetes risk and identify a subgroup of patients sensitive to sulfonylureas by Meulebrouck, Sarah, Scherrer, Victoria, Boutry, Raphaël, Toussaint, Bénédicte, Vaillant, Emmanuel, Dechaume, Aurélie, Loiselle, Hélène, Balkau, Beverley, Charpentier, Guillaume, Franc, Sylvia, Marre, Michel, Baron, Morgane, Vaxillaire, Martine, Derhourhi, Mehdi, Boissel, Mathilde, Froguel, Philippe, Bonnefond, Amélie

Get full text

Dominant PDX1 deficiency causes highly penetrant diabetes at different ages, associated with obesity and exocrine pancreatic deficiency: Lessons for precision medicine by Kouidrat, Youssef, Le Collen, Lauriane, Vaxillaire, Martine, Dechaume, Aurélie, Toussaint, Bénédicte, Vaillant, Emmanuel, Amanzougarene, Souhila, Derhourhi, Mehdi, Delemer, Brigitte, Azahaf, Mustapha, Froguel, Philippe, Bonnefond, Amélie

Get full text

The loss-of-function PCSK9 p.R46L genetic variant does not alter glucose homeostasis by Bonnefond, Amélie, Yengo, Loïc, Le May, Cédric, Fumeron, Fréderic, Marre, Michel, Balkau, Beverley, Charpentier, Guillaume, Franc, Sylvia, Froguel, Philippe, Cariou, Bertrand

Get full text

Genetic variants of interferon-response factor 5 are associated with the incidence of chronic kidney disease: the D.E.S.I.R. study by Fumeron, Frédéric, Velho, Gilberto, Alzaid, Fawaz, El Boustany, Ray, Vandiedonck, Claire, Bonnefond, Amélie, Froguel, Philippe, Potier, Louis, Marre, Michel, Balkau, Beverley, Roussel, Ronan, Venteclef, Nicolas

Get full text

Childhood Obesity Is Associated with Shorter Leukocyte Telomere Length by Buxton, Jessica L, Walters, Robin G, Visvikis-Siest, Sophie, Meyre, David, Froguel, Philippe, Blakemore, Alexandra I. F

Get full text

Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity by Kilpeläinen, Tuomas O., Ntalla, Ioanna, Aschard, Hugues, Vojinovic, Dina, Aslibekyan, Stella, Feitosa, Mary F., Musani, Solomon K., Wang, Zhe, Bartz, Traci M., Bielak, Lawrence F., Hartwig, Fernando P., Horimoto, Andrea R. V. R., Li, Changwei, Sim, Xueling, Smith, Albert V., Alver, Maris, Amini, Marzyeh, Divers, Jasmin, Evangelou, Evangelos, Gao, Chuan, Harris, Sarah E., Zhao, Jing Hua, Kraja, Aldi T., Kühnel, Brigitte, Nolte, Ilja M., Rauramaa, Rainer, Riaz, Muhammad, Robino, Antonietta, Rueedi, Rico, Takeuchi, Fumihiko, Varga, Tibor V., Li, Xiaoyin, Amin, Najaf, Arnett, Donna K., Canouil, Mickaël, Chen, Yii-Der Ida, de Mutsert, Renée, de Silva, H. Janaka, Demirkan, Ayşe, Ding, Jingzhong, Eaton, Charles B., Gabriel, Kelley P., Giulianini, Franco, Gu, Chi Charles, Gu, Dongfeng, Harris, Tamara B., Heikkinen, Sami, Jonas, Jost B., Koh, Woon-Puay, Komulainen, Pirjo, Kritchevsky, Stephen B., Langefeld, Carl D., Launer, Lenore J., Leander, Karin, Lemaitre, Rozenn N., Liang, Jingjing, Mägi, Reedik, Mohlke, Karen L., Nwuba, Chiamaka Vivian, O’Connell, Jeff, Papanicolau, George J., Peters, Annette, Peyser, Patricia A., Polasek, Ozren, Poveda, Alaitz, Rose, Lynda M., Rudan, Igor, Sidney, Stephen S., Starr, John M., Sternfeld, Barbara, Tang, Hua, van Heemst, Diana, Xiang, Yong-Bing, Yu, Caizheng, Yuan, Jian-Min, Boehnke, Michael, Bowden, Donald W., de Faire, Ulf, Deary, Ian J., Gieger, Christian, Samani, Nilesh J., van der Harst, Pim, Van Vliet-Ostaptchouk, Jana V., Wareham, Nicholas J., Weir, David R., Wu, Tangchun, Franks, Paul W., Hayward, Caroline, Kardia, Sharon L. R., Mook-Kanamori, Dennis O., Province, Michael A., Redline, Susan, van Duijn, Cornelia M., Rotter, Jerome I., Gauderman, W. James, Munroe, Patricia B., Fornage, Myriam, Cupples, L. Adrienne, Rao, Dabeeru C., Loos, Ruth J. F.

Get full text

Genetic Loci Associated With C-Reactive Protein Levels and Risk of Coronary Heart Disease by Elliott, Paul, Chambers, John C, Zhang, Weihua, Clarke, Robert, Hopewell, Jemma C, Peden, John F, Erdmann, Jeanette, Braund, Peter, Engert, James C, Bennett, Derrick, Coin, Lachlan, Ashby, Deborah, Tzoulaki, Ioanna, Brown, Ian J, Mt-Isa, Shahrul, McCarthy, Mark I, Peltonen, Leena, Freimer, Nelson B, Farrall, Martin, Ruokonen, Aimo, Hamsten, Anders, Lim, Noha, Froguel, Philippe, Waterworth, Dawn M, Vollenweider, Peter, Waeber, Gerard, Jarvelin, Marjo-Riitta, Mooser, Vincent, Scott, James, Hall, Alistair S, Schunkert, Heribert, Anand, Sonia S, Collins, Rory, Samani, Nilesh J, Watkins, Hugh, Kooner, Jaspal S

Get full text

Epigenetic changes associated with hyperglycaemia exposure in the longitudinal D.E.S.I.R. cohort by Khamis, Amna, Ning, Lijiao, Balkau, Beverley, Bonnefond, Amélie, Canouil, Mickaël, Roussel, Ronan, Froguel, Philippe

Get full text

Lack of association between the Pro12Ala polymorphism of the PPAR-γ2 gene and type 2 diabetes mellitus in the Qatari consanguineous population by Badii, Ramin, Bener, Abdulbari, Zirie, Mahmoud, Al-Rikabi, Ammar, Simsek, Mehmet, Al-Hamaq, Abdulla O. A. A., Ghoussaini, Maya, Froguel, Philippe, Wareham, Nick J.

Get full text

What should the genome-wide significance threshold be? Empirical replication of borderline genetic associations by PANAGIOTOU, Orestis A, IOANNIDIS, John P. A

Get full text

Pluripotent stem cells as a potential tool for disease modelling and cell therapy in diabetes by Abdelalim, Essam M, Bonnefond, Amélie, Bennaceur-Griscelli, Annelise, Froguel, Philippe

Get full text

A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism by de Smith, Adam J., Purmann, Carolin, Walters, Robin G., Ellis, Richard J., Holder, Susan E., Van Haelst, Mieke M., Brady, Angela F., Fairbrother, Una L., Dattani, Mehul, Keogh, Julia M., Henning, Elana, Yeo, Giles S.H., O'Rahilly, Stephen, Froguel, Philippe, Farooqi, I. Sadaf, Blakemore, Alexandra I.F.

Get full text

PLCL1 rs7595412 variation is not associated with hip bone size variation in postmenopausal Danish women by Cauchi, Stéphane, Byrjalsen, Inger, Durand, Emmanuelle, Karsdal, Morten A, Froguel, Philippe

Get full text

Postnatal weight and height growth velocities at different ages between birth and 5 y and body composition in adolescent boys and girls by Botton, Jérémie, Heude, Barbara, Maccario, Jean, Ducimetière, Pierre, Charles, Marie-Aline

Get full text

Epigenetic and Transcriptomic Programming of HSC Quiescence Signaling in Large for Gestational Age Neonates by Pelletier, Alexandre, Carrier, Arnaud, Zhao, Yongmei, Canouil, Mickaël, Derhourhi, Mehdi, Durand, Emmanuelle, Berberian-Ferrato, Lionel, Greally, John, Hughes, Francine, Froguel, Philippe, Bonnefond, Amélie, Delahaye, Fabien

Get full text