Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587 by Figueroa, Javier, Phillips, Lynette M, Shahar, Tal, Hossain, Anwar, Gumin, Joy, Kim, Hoon, Bean, Andrew J, Calin, George A, Fueyo, Juan, Walters, Edgar T, Kalluri, Raghu, Verhaak, Roel G, Lang, Frederick F

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IGFBP2 Activates the NF-κB Pathway to Drive Epithelial-Mesenchymal Transition and Invasive Character in Pancreatic Ductal Adenocarcinoma by Gao, Song, Sun, Yan, Zhang, Xuebin, Hu, Limei, Liu, Yuexin, Chua, Corrine Yingxuan, Phillips, Lynette M, Ren, He, Fleming, Jason B, Wang, Huamin, Chiao, Paul J, Hao, Jihui, Zhang, Wei

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Tumor-specific polycistronic miRNA delivered by engineered exosomes for the treatment of glioblastoma by McDonald, Malcolm F, Hossain, Anwar, Momin, Eric N, Hasan, Irtiza, Singh, Sanjay, Adachi, Satoshi, Gumin, Joy, Ledbetter, Daniel, Yang, Jing, Long, Lihong, Daou, Marc, Gopakumar, Sricharan, Phillips, Lynette M, Parker Kerrigan, Brittany, Lang, Frederick F

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Glioma progression is mediated by an addiction to aberrant IGFBP2 expression and can be blocked using anti-IGFBP2 strategies by Phillips, Lynette M, Zhou, Xinhui, Cogdell, David E, Chua, Corrine Yingxuan, Huisinga, Anouk, R Hess, Kenneth, Fuller, Gregory N, Zhang, Wei

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An immune-competent, replication-permissive Syrian Hamster glioma model for evaluating Delta-24-RGD oncolytic adenovirus by Phillips, Lynette M, Li, Shoudong, Gumin, Joy, Daou, Marc, Ledbetter, Daniel, Yang, Jing, Singh, Sanjay, Parker Kerrigan, Brittany C, Hossain, Anwar, Yuan, Ying, Gomez-Manzano, Candelaria, Fueyo, Juan, Lang, Frederick F

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Driver or passenger effects of augmented c-Myc and Cdc20 in gliomagenesis by Ji, Ping, Zhou, Xinhui, Liu, Qun, Fuller, Gregory N, Phillips, Lynette M, Zhang, Wei

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TMIC-46. TRANSCRIPTIONAL HETEROGENEITY AND MECHANISTIC PATHWAYS OF RECURRENT GLIOBLASTOMA: INSIGHTS FROM A PRE-CLINICAL RECURRENT TUMOR MODEL by Fayyad Zaman, Mohammad, Daou, Marc, Phillips, Lynette M, Singh, Sanjay, Long, Lihong, Gumin, Joy, Ledbetter, Daniel, Lang, Frederick F

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Abstract 1736: Targeting Hsp90-Cdc37 complex overcomes drug resistance in glioma cells harboring FGFR3-TACC3 fusion gene by Li, Tao, Mehraein-Ghomi, Farideh, Namjoshi, Sanjeev V., Phillips, Lynette M., Ballard, Elizabeth A., Forbes, Mary E., Chou, ping-Chieh, Yang, Xuejun, Zhang, Wei

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Glioma progression is mediated by an addiction to aberrant IGFBP2 expression and can be blocked using anti-IGFBP2 strategies: Reversible effects of IGFBP2 expression mediate glioma... by Phillips, Lynette M, Zhou, Xinhui, Cogdell, David E, Chua, Corrine Yingxuan, Huisinga, Anouk, R Hess, Kenneth, Fuller, Gregory N, Zhang, Wei

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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program by Taliun, Daniel, Kessler, Michael D., Carlson, Jedidiah, Taliun, Sarah A. Gagliano, Kang, Hyun Min, Pitsillides, Achilleas N., Emde, Anne-Katrin, Clarke, Wayne E., Shetty, Amol C., Wong, Quenna, Bobo, Dean M., Aguet, François, Albert, Christine, Aslibekyan, Stella, Barnard, John, Barr, R. Graham, Barwick, Lucas, Becker, Lewis C., Bielak, Lawrence F., Blangero, John, Bowden, Donald W., Burchard, Esteban G., Chalazan, Brandon, Chasman, Daniel I., Chen, Yii-Der Ida, Choi, Seung Hoan, Chung, Mina K., Curran, Joanne E., Daya, Michelle, Ellinor, Patrick T., Fatkin, Diane, Fingerlin, Tasha, Forer, Lukas, Franceschini, Nora, Germer, Soren, Gladwin, Mark T., Hall, Michael E., He, Jiang, Johnsen, Jill M., Johnson, Andrew D., Kardia, Sharon L. R., Klemmer, Robert, Kooperberg, Charles, Köttgen, Anna, Lange, Leslie A., Lin, Xihong, Lin, Keng-Han, Liu, Chunyu, Loos, Ruth J. F., Gerszten, Robert, Lunetta, Kathryn L., Mak, Angel C. Y., Manichaikul, Ani, Manning, Alisa K., Mathias, Rasika A., McManus, David D., McGarvey, Stephen T., Meigs, James B., Minear, Mollie A., Mitchell, Braxton D., Mohanty, Sanghamitra, Montasser, May E., Montgomery, Courtney, Morrison, Alanna C., Murabito, Joanne M., Natale, Andrea, Nelson, Sarah C., Palmer, Nicholette D., Pankratz, Nathan, Peyser, Patricia A., Post, Wendy S., Psaty, Bruce M., Rao, D. C., Reiner, Alexander P., Roden, Dan, Rotter, Jerome I., Schoenherr, Sebastian, Seo, Jeong-Sun, Sheu, Wayne H., Smith, Nicholas L., Smith, Jennifer A., Stilp, Adrienne M., Telen, Marilyn, Thornton, Timothy A., Tracy, Russell P., Van Den Berg, David J., Vasan, Ramachandran S., Vrieze, Scott, Weng, Lu-Chen, Zhao, Xutong, Boerwinkle, Eric, Gibbs, Richard, Rich, Stephen S., Silverman, Edwin K., Qasba, Pankaj, Gan, Weiniu, Zöllner, Sebastian, Wilson, James G., Laurie, Cathy C., Jaquish, Cashell E.

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Inherited causes of clonal haematopoiesis in 97,691 whole genomes by Weinstock, Joshua S., Nandakumar, Satish K., Bao, Erik L., Szeto, Mindy D., Liao, Xiaotian, Nasser, Joseph, Laurie, Cecelia, Burugula, Bala Bharathi, Gibson, Christopher J., Lin, Amy E., Aguet, Francois, Ardlie, Kristin, Mitchell, Braxton D., Barnes, Kathleen C., Moscati, Arden, Redline, Susan, Psaty, Bruce M., Silverman, Edwin K., Weiss, Scott T., Palmer, Nicholette D., Vasan, Ramachandran S., Burchard, Esteban G., He, Jiang, Kaplan, Robert C., Smith, Nicholas L., Arnett, Donna K., Schwartz, David A., Guo, Xiuqing, Konkle, Barbara A., Custer, Brian, Peralta, Juan M., Gui, Hongsheng, Meyers, Deborah A., McGarvey, Stephen T., Chen, Ida Yii-Der, Shoemaker, M. Benjamin, Peyser, Patricia A., Broome, Jai G., Wang, Fei Fei, North, Kari E., Launer, Lenore J., Cade, Brian E., Bis, Joshua C., Cho, Michael H., Lasky-Su, Jessica, Bowden, Donald W., Cupples, L. Adrienne, Mak, Angel C. Y., Smith, Jennifer A., Kelly, Tanika N., Aslibekyan, Stella, Heckbert, Susan R., Tiwari, Hemant K., Yang, Ivana V., Heit, John A., Johnsen, Jill M., Curran, Joanne E., Wenzel, Sally E., Rao, Dabeeru C., Darbar, Dawood, Moon, Jee-Young, Tracy, Russell P., Buth, Erin J., Rafaels, Nicholas, Loos, Ruth J. F., Liu, Yongmei, Hou, Lifang, Lee, Jiwon, Kachroo, Priyadarshini, Freedman, Barry I., Levy, Daniel, Bielak, Lawrence F., Hixson, James E., Floyd, James S., Whitsel, Eric A., Ellinor, Patrick T., Irvin, Marguerite R., Fingerlin, Tasha E., Armasu, Sebastian M., Wheeler, Marsha M., Blangero, John, Williams, L. Keoki, Levy, Bruce D., Sheu, Wayne Huey-Herng, Roden, Dan M., Taylor, Kent D., Johnson, Andrew D., Auer, Paul L., Kooperberg, Charles, Laurie, Cathy C., Blackwell, Thomas W., Smith, Albert V., Lange, Ethan, Rotter, Jerome I., Kitzman, Jacob O., Lander, Eric S., Ebert, Benjamin L., Reiner, Alexander P., Jaiswal, Siddhartha, Kathiresan, Sekar

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Pd-Catalyzed Synthesis of Aryl and Heteroaryl Triflones from Reactions of Sodium Triflinate with Aryl (Heteroaryl) Triflates by Smyth, Lynette A, Phillips, Eric M, Chan, Vincent S, Napolitano, José G, Henry, Rodger, Shekhar, Shashank

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Rare variants in RTEL1 are associated with familial interstitial pneumonia by Cogan, Joy D, Kropski, Jonathan A, Zhao, Min, Mitchell, Daphne B, Rives, Lynette, Markin, Cheryl, Garnett, Errine T, Montgomery, Keri H, Mason, Wendi R, McKean, David F, Powers, Julia, Murphy, Elissa, Olson, Lana M, Choi, Leena, Cheng, Dong-Sheng, Blue, Elizabeth Marchani, Young, Lisa R, Lancaster, Lisa H, Steele, Mark P, Brown, Kevin K, Schwarz, Marvin I, Fingerlin, Tasha E, Schwartz, David A, Lawson, William E, Loyd, James E, Zhao, Zhongming, Phillips, 3rd, John A, Blackwell, Timothy S

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Probable digenic inheritance of Diamond–Blackfan anemia by Furuta, Yutaka, Tinker, Rory J, Gulsevin, Alican, Neumann, Serena M., Hamid, Rizwan, Cogan, Joy D., Rives, Lynette, Liu, Qi, Chen, Hua‐Chang, Joos, Karen M., Phillips, John A.

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Review and metabolomic profiling of unsolved case reveals newly reported autosomal dominant congenital disorder of glycosylation, type Iw formerly thought to only be an autosomal r... by Ezell, Kimberly M., Furuta, Yutaka, Oglesbee, Devin, Pivnick, Eniko K., Rinker, David, Sheehan, Jonathan H., Tinker, Rory J., Hamid, Rizwan, Cogan, Joy D., Rives, Lynette, Neumann, Serena, Corner, Brian, Koziura, Mary, Phillips, John A.

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Measuring Debilitating and Facilitating Anxiety Within Nursing Simulation by Reed, Janet M., Dodson, Tracy, Phillips, Lynette, Petrinec, Amy

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Innate killing of Leishmania donovani by macrophages of the splenic marginal zone requires IRF-7 by Phillips, Rebecca, Svensson, Mattias, Aziz, Naveed, Maroof, Asher, Brown, Najmeeyah, Beattie, Lynette, Signoret, Nathalie, Kaye, Paul M

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A medical odyssey of a 72‐year‐old man with Charcot–Marie–Tooth disease type 2 newly diagnosed with biallelic variants in SORD gene causing sorbitol dehydrogenase deficiency... by Furuta, Yutaka, Nelson, Erica T., Neumann, Serena M., Phillips, John A., Hamid, Rizwan, Tinker, Rory J., Cogan, Joy D., Rives, Lynette, Newman, John H.

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Whole genome sequence analysis of blood lipid levels in >66,000 individuals by Selvaraj, Margaret Sunitha, Li, Xihao, Li, Zilin, Pampana, Akhil, Zhang, David Y., Park, Joseph, Aslibekyan, Stella, Bis, Joshua C., Brody, Jennifer A., Cade, Brian E., Chuang, Lee-Ming, Chung, Ren-Hua, Curran, Joanne E., de las Fuentes, Lisa, de Vries, Paul S., Duggirala, Ravindranath, Freedman, Barry I., Graff, Mariaelisa, Guo, Xiuqing, Heard-Costa, Nancy, Hidalgo, Bertha, Hwu, Chii-Min, Irvin, Marguerite R., Kelly, Tanika N., Kral, Brian G., Lange, Leslie, Li, Xiaohui, Lisa, Martin, Lubitz, Steven A., Manichaikul, Ani W., Michael, Preuss, Montasser, May E., Morrison, Alanna C., Naseri, Take, O’Connell, Jeffrey R., Palmer, Nicholette D., Peyser, Patricia A., Reupena, Muagututia S., Smith, Jennifer A., Sun, Xiao, Taylor, Kent D., Tracy, Russell P., Tsai, Michael Y., Wang, Zhe, Wang, Yuxuan, Bao, Wei, Wilkins, John T., Yanek, Lisa R., Zhao, Wei, Arnett, Donna K., Blangero, John, Boerwinkle, Eric, Bowden, Donald W., Chen, Yii-Der Ida, Correa, Adolfo, Cupples, L. Adrienne, Dutcher, Susan K., Ellinor, Patrick T., Fornage, Myriam, Gabriel, Stacey, Germer, Soren, Gibbs, Richard, He, Jiang, Kaplan, Robert C., Kardia, Sharon L. R., Kim, Ryan, Kooperberg, Charles, Loos, Ruth J. F., Viaud-Martinez, Karine A, Mathias, Rasika A., McGarvey, Stephen T., Mitchell, Braxton D., Nickerson, Deborah, North, Kari E., Psaty, Bruce M., Redline, Susan, Reiner, Alexander P., Vasan, Ramachandran S., Rich, Stephen S., Willer, Cristen, Rotter, Jerome I., Rader, Daniel J., Lin, Xihong, Peloso, Gina M., Natarajan, Pradeep

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Exome sequencing of 457 autism families recruited online provides evidence for autism risk genes by Feliciano, Pamela, Zhou, Xueya, Astrovskaya, Irina, Turner, Tychele N., Wang, Tianyun, Brueggeman, Leo, Barnard, Rebecca, Hsieh, Alexander, Snyder, LeeAnne Green, Muzny, Donna M., Sabo, Aniko, Gibbs, Richard A., Eichler, Evan E., O’Roak, Brian J., Michaelson, Jacob J., Volfovsky, Natalia, Shen, Yufeng, Chung, Wendy K.

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