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Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics
by
YANG, Yili
,
KITAGAKI, Jirouta
,
LI, Chou-Chi H
,
KENTEN, John H
,
BEUTLER, John A
,
VOUSDEN, Karen H
,
WEISSMAN, Allan M
,
DAI, Ren-Ming
,
YIEN CHE TSAI
,
LORICK, Kevin L
,
LUDWIG, Robert L
,
PIERRE, Shervon A
,
JENSEN, Jane P
,
DAVYDOV, Ilia V
,
OBEROI, Pankaj
Published in
Cancer research (Chicago, Ill.)
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Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells
by
Yang, Yili
,
Ludwig, Robert L.
,
Jensen, Jane P.
,
Pierre, Shervon A.
,
Medaglia, Maxine V.
,
Davydov, Ilia V.
,
Safiran, Yassamin J.
,
Oberoi, Pankaj
,
Kenten, John H.
,
Phillips, Andrew C.
,
Weissman, Allan M.
,
Vousden, Karen H.
Published in
Cancer cell
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Cancer Cell
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Cancer Research
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Apoptosis - Drug Effects
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Cell Line, Tumor
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Life Sciences & Biomedicine
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Mice
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Oncology
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Tumor Suppressor Protein P53 - Metabolism
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Ubiquitin - Metabolism
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Antineoplastic Agents
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Biological And Medical Sciences
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Cell Cycle Proteins - Metabolism
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Cyclin-Dependent Kinase 4
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