Translational PK/PD for the Development of Novel Antibiotics-A Drug Developer's Perspective by Bissantz, Caterina, Zampaloni, Claudia, David-Pierson, Pascale, Dieppois, Guennaelle, Guenther, Andreas, Trauner, Andrej, Winther, Lotte, Stubbings, William

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Cryopreserved human hepatocytes in suspension are a convenient high throughput tool for the prediction of metabolic clearance by Jouin, Delphine, Blanchard, Nadège, Alexandre, Eliane, Delobel, Frédéric, David-Pierson, Pascale, Lavé, Thierry, Jaeck, Daniel, Richert, Lysiane, Coassolo, Philippe

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Simulation-Based Evaluation of PK/PD Indices for Meropenem Across Patient Groups and Experimental Designs by Kristoffersson, Anders N., David-Pierson, Pascale, Parrott, Neil J., Kuhlmann, Olaf, Lave, Thierry, Friberg, Lena E., Nielsen, Elisabet I.

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Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy by Ratni, Hasane, Karp, Gary M, Weetall, Marla, Naryshkin, Nikolai A, Paushkin, Sergey V, Chen, Karen S, McCarthy, Kathleen D, Qi, Hongyan, Turpoff, Anthony, Woll, Matthew G, Zhang, Xiaoyan, Zhang, Nanjing, Yang, Tianle, Dakka, Amal, Vazirani, Priya, Zhao, Xin, Pinard, Emmanuel, Green, Luke, David-Pierson, Pascale, Tuerck, Dietrich, Poirier, Agnes, Muster, Wolfgang, Kirchner, Stephan, Mueller, Lutz, Gerlach, Irene, Metzger, Friedrich

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β‑Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease by Hilpert, Hans, Guba, Wolfgang, Woltering, Thomas J, Wostl, Wolfgang, Pinard, Emmanuel, Mauser, Harald, Mayweg, Alexander V, Rogers-Evans, Mark, Humm, Roland, Krummenacher, Daniela, Muser, Thorsten, Schnider, Christian, Jacobsen, Helmut, Ozmen, Laurence, Bergadano, Alessandra, Banner, David W, Hochstrasser, Remo, Kuglstatter, Andreas, David-Pierson, Pascale, Fischer, Holger, Polara, Alessandra, Narquizian, Robert

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Translating pharmacology models effectively to predict therapeutic benefit by Dudal, Sherri, Bissantz, Caterina, Caruso, Antonello, David-Pierson, Pascale, Driessen, Wouter, Koller, Erich, Krippendorff, Ben-Fillippo, Lechmann, Martin, Olivares-Morales, Andrés, Paehler, Axel, Rynn, Caroline, Türck, Dietrich, Van De Vyver, Arthur, Wang, Ken, Winther, Lotte

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Aminothiazoles as γ-secretase modulators by Lübbers, Thomas, Flohr, Alexander, Jolidon, Synese, David-Pierson, Pascale, Jacobsen, Helmut, Ozmen, Laurence, Baumann, Karlheinz

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Aminothiazoles as [gamma]-secretase modulators by Luebbers, Thomas, Flohr, Alexander, Jolidon, Synese, David-Pierson, Pascale, Jacobsen, Helmut, Ozmen, Laurence, Baumann, Karlheinz

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Novel orally active, dibenzazepinone-based γ-secretase inhibitors by Peters, Jens-Uwe, Galley, Guido, Jacobsen, Helmut, Czech, Christian, David-Pierson, Pascale, Kitas, Eric A., Ozmen, Laurence

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5-Hydroxyindole-2-carboxylic Acid Amides: Novel Histamine-3 Receptor Inverse Agonists for the Treatment of Obesity by Pierson, Pascale David, Fettes, Alec, Freichel, Christian, Gatti-McArthur, Silvia, Hertel, Cornelia, Huwyler, Jörg, Mohr, Peter, Nakagawa, Toshito, Nettekoven, Matthias, Plancher, Jean-Marc, Raab, Susanne, Richter, Hans, Roche, Olivier, Rodríguez Sarmiento, Rosa María, Schmitt, Monique, Schuler, Franz, Takahashi, Tadakatsu, Taylor, Sven, Ullmer, Christoph, Wiegand, Ruby

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Benzodioxoles: Novel Cannabinoid-1 Receptor Inverse Agonists for the Treatment of Obesity by Alig, Leo, Alsenz, Jochem, Andjelkovic, Mirjana, Bendels, Stefanie, Bénardeau, Agnès, Bleicher, Konrad, Bourson, Anne, David-Pierson, Pascale, Guba, Wolfgang, Hildbrand, Stefan, Kube, Dagmar, Lübbers, Thomas, Mayweg, Alexander V, Narquizian, Robert, Neidhart, Werner, Nettekoven, Matthias, Plancher, Jean-Marc, Rocha, Cynthia, Rogers-Evans, Mark, Röver, Stephan, Schneider, Gisbert, Taylor, Sven, Waldmeier, Pius

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Substituted 2-oxo-azepane derivatives are potent, orally active γ-secretase inhibitors by Kitas, Eric A., Galley, Guido, Jakob-Roetne, Roland, Flohr, Alexander, Wostl, Wolfgang, Mauser, Harald, Alker, André M., Czech, Christian, Ozmen, Laurence, David-Pierson, Pascale, Reinhardt, Dieter, Jacobsen, Helmut

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