Proposed Therapeutic Range of Treosulfan in Reduced Toxicity Pediatric Allogeneic Hematopoietic Stem Cell Transplant Conditioning: Results From a Prospective Trial by Chiesa, Robert, Standing, Joseph F., Winter, Robert, Nademi, Zohreh, Chu, Jan, Pinner, Danielle, Kloprogge, Frank, McLellen, Susan, Amrolia, Persis J., Rao, Kanchan, Lucchini, Giovanna, Silva, Juliana, Ciocarlie, Oana, Lazareva, Arina, Gennery, Andrew R., Doncheva, Bilyana, Cant, Andrew J., Hambleton, Sophie, Flood, Terence, Rogerson, Elizabeth, Devine, Kirsty, Prunty, Helen, Heales, Simon, Veys, Paul, Slatter, Mary

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Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells by Qasim, Waseem, Zhan, Hong, Samarasinghe, Sujith, Adams, Stuart, Amrolia, Persis, Stafford, Sian, Butler, Katie, Rivat, Christine, Wright, Gary, Somana, Kathy, Ghorashian, Sara, Pinner, Danielle, Ahsan, Gul, Gilmour, Kimberly, Lucchini, Giovanna, Inglott, Sarah, Mifsud, William, Chiesa, Robert, Peggs, Karl S, Chan, Lucas, Farzeneh, Farzin, Thrasher, Adrian J, Vora, Ajay, Pule, Martin, Veys, Paul

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Genome-edited, donor-derived allogeneic anti-CD19 chimeric antigen receptor T cells in paediatric and adult B-cell acute lymphoblastic leukaemia: results of two phase 1 studies by Benjamin, Reuben, Yallop, Deborah, Jozwik, Agnieszka, Mirci-Danicar, Oana C, Lucchini, Giovanna, Pinner, Danielle, Jain, Nitin, Maus, Marcela V, Frigault, Matthew J, Mohty, Mohamad, Gianella-Borradori, Athos, Binlich, Florence, Vitry, Fabien, Thomas, Elisabeth, Philippe, Anne, Dupouy, Sandra, Marchiq, Ibtissam, Almena-Carrasco, Maria, Ferry, Nicolas, Veys, Paul, Qasim, Waseem, Graham, Charlotte, Yallop, Deborah, Jozwik, Agnieszka, Pagliuca, Antonio, Kassam, Shireen, Kazmi, Majid, Kuhnl, Andrea, Metaxa, Victoria, Bonganay, Laarni, Stewart, Orla, Catt, Lorraine, Lewis, Jen, Farzaneh, Farzin, Chappell, Jackie, Mason, Alice, Dunlop, Alan, Cheung, Gary, Giemza, Elka, Qasim, Waseem, Ciocarlie, Oana, Lucchini, Giovanna, Pinner, Danielle, Chu, Jan, Amrolia, Persis, Chiesa, Robert, Silva, Juliana, Finch, Maria, Young, Lindsey, Samarasinghe, Sujith, Rao, Anupama, Vora, Ajay, Gilmour, Kimberley, Rivat, Christine, Murphy, Clare, Ahsan, Gulrukh, Said Shamsah, Rasha, James, Jesmina, Inglott, Sarah, Wright, Gary, Izotova, Natalia, Jain, Nitin, Konopleva, Marina, Wierda, William, Jabbour, Elias, Kebrieai, Partow, McGee, Kara, Frigault, Matthew, Brown, Jami, Hock, Hanno, McKeown, Meaghan A, Mathews, Richard, Spitzer, Thomas, Boissel, Nicolas, Raffoux, Emmanuel, Lengliné, Etienne, Itzykson, Raphael, Rabian, Florence, Larghero, Jérôme, Madelaine, Isabelle, Azoulay, Elie, Caillat-Zucman, Sophie, Meunier, Martine, Celli-Lebras, Karine, Tremorin, Marie-Thérèse, Baruchel, André, Grain, Audrey, Alimi, Aurélia, Roupret, Julie, Chaillou, Delphine, Fenneteau, Odile, Lainey, Elodie, Naudin, Jerome, Brissot, Eolia, Dulery, Remy, Malard, Florent, Mediavilla, Clémence, Bonnin, Agnès, Ledraa, Tounes, Daguenel-Nguyen, Anne

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Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia by Ottaviano, Giorgio, Georgiadis, Christos, Gkazi, Soragia Athina, Syed, Farhatullah, Zhan, Hong, Etuk, Annie, Preece, Roland, Chu, Jan, Kubat, Agnieszka, Adams, Stuart, Veys, Paul, Vora, Ajay, Rao, Kanchan, Qasim, Waseem

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CD19/CD22 targeting with cotransduced CAR T cells to prevent antigen-negative relapse after CAR T-cell therapy for B-cell ALL by Ghorashian, Sara, Lucchini, Giovanna, Richardson, Rachel, Nguyen, Kyvi, Terris, Craig, Guvenel, Aleks, Oporto-Espuelas, Macarena, Yeung, Jenny, Pinner, Danielle, Chu, Jan, Williams, Lindsey, Ko, Ka-Yuk, Walding, Chloe, Watts, Kelly, Inglott, Sarah, Thomas, Rebecca, Connor, Christopher, Adams, Stuart, Gravett, Emma, Gilmour, Kimberly, Lal, Alka, Kunaseelan, Sangeetha, Popova, Bilyana, Lopes, Andre, Ngai, Yenting, Hackshaw, Allan, Kokalaki, Evangelia, Carulla, Milena Balasch, Mullanfiroze, Khushnuma, Lazareva, Arina, Pavasovic, Vesna, Rao, Anupama, Bartram, Jack, Vora, Ajay, Chiesa, Robert, Silva, Juliana, Rao, Kanchan, Bonney, Denise, Wynn, Robert, Pule, Martin, Hough, Rachael, Amrolia, Persis J

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TT52CAR19: Phase 1 Trial of CRISPR/Cas9 Edited Allogeneic CAR19 T Cells for Paediatric Relapsed/Refractory B-ALL by Ottaviano, Giorgio, Georgiadis, Christos, Syed, Farhatullah, Gkazi, Soragia Athina, Zhan, Hong, Etuk, Annie, Chu, Jan, Pinner, Danielle, Inglott, Sarah, Gilmour, Kimberly, Adams, Stuart, Kricke, Susanne, Izotova, Natalia, Ladon, Dariusz, Kubat, Agnieszka, Veys, Paul, Vora, Ajay, Rao, Kanchan, Qasim, Waseem

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Tvt CAR7: Phase 1 Clinical Trial of Base-Edited "Universal” CAR7 T Cells for Paediatric Relapsed/Refractory T-ALL by Chiesa, Robert, Georgiadis, Christos, Ottaviano, Giorgio, Syed, Farhatullah, Braybrook, Toni, Etuk, Annie, Zhan, Hong, Gkazi, Soragia Athina, Preece, Roland, Adams, Stuart, Thomas, Rebecca, Awuah, Arnold, Gilmour, Kimberly, Mhaldien, Lana, Chu, Jan, Pinner, Danielle, Kubat, Agnieszka, Veys, Paul, Rao, Kanchan, Lucchini, Giovanna, O'Connor, David, Vora, Ajay, Qasim, Waseem

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Dual Antigen Targeting with Co-Transduced CD19/22 CAR T Cells May Prevent Antigen-Negative Relapse after CAR T Cell Therapy for Relapsed/Refractory ALL by Ghorashian, Sara, Lucchini, Giovanna, Richardson, Rachel, Nguyen, Kyvi, Terris, Craig, Oporto-Espuelas, Macarena, Yeung, Jenny, Pinner, Danielle, Chu, Jan, Williams, Lindsey, Ko, Ka-yuk, Walding, Chloe, Watts, Kelly, Inglott, Sarah, Adams, Stuart, Gravett, Emma, Gilmour, Kimberly, Lal, Alka, Kunaseelan, Sangeetha, Popova, Bilyana, Lopes, Andre, Ngai, Yenting, Kokalaki, Evangelia K, Balasch Carulla, Milena, Mullanfiroze, Khushnuma, Lazareva, Arina, Pavasovic, Vesna, Rao, Anupama, Bartram, Jack, Vora, Ajay, Chiesa, Robert, Silva, Juliana, Rao, Kanchan, Clesham, Katherine, Bonney, Denise, Wynn, Robert F, Pule, Martin, Hough, Rachael E, Amrolia, Persis J

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Therapy of Paediatric B-ALL with a Fast Off Rate CD19 CAR Leads to Enhanced Expansion and Prolonged CAR T Cell Persistence in Patients with Low Bone Marrow Tumour Burden, and Is As... by Ghorashian, Sara, Kramer, Anne Marijn, Onuoha, Shimobi, Wright, Gary, Bartram, Jack Luke, Richardson, Rachel, Albon, Sarah J, Casanovas Company, Joan, Castro, Fernanda, Popova, Bilyana, Villanueva, Krystal, Yeung, Jenny, Guvenel, Aleks, Wawrzyniecka, Patrycja, Pinner, Danielle, Chu, Jan, Lucchini, Giovanna, Silva, Juliana, Ciocarlie, Oana, Lazareva, Arina, Inglott, Sarah, Gilmour, Kimberly, Ahsan, Gulrukh, Champion, Kim, Lopes, Andre, Hackshaw, Allan, Farzaneh, Farzin, Chiesa, Robert, Rao, Kanchan, Bonney, Denise, Samarasinghe, Sujith, Goulden, Nicholas John, Vora, Ajay, Veys, Paul, Hough, Rachael E, Wynn, Robert, Pule, Martin, Amrolia, Persis J

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A Novel Low Affinity CD19CAR Results in Durable Disease Remissions and Prolonged CAR T Cell Persistence without Severe CRS or Neurotoxicity in Patients with Paediatric ALL by Ghorashian, Sara, Kramer, Anne Marijn, Albon, Sarah Jayne, Wright, Gary, Castro, Fernanda, Popova, Bilyana, Casanovas Company, Joan, Irving, Catherine, Vetharoy, Winston, Richardson, Rachel, Pinner, Danielle, Chu, Jan, Lucchini, Giovanna, Silva, Juliana, Ciocarlie, Oana, Inglott, Sarah, Champion, Kim, Hackshaw, Allan, Farzaneh, Farzin, Chiesa, Robert, Rao, Kanchan, Rao, Anupama Gopala, Ancliffe, Philip, Samarasinghe, Sujith, Vora, Ajay, Veys, Paul, Hough, Rachael, Wynn, Robert, Pule, Martin, Amrolia, Persis J

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Preliminary Results of UCART19, an Allogeneic Anti-CD19 CAR T-Cell Product in a First-in-Human Trial (PALL) in Pediatric Patients with CD19+ Relapsed/Refractory B-Cell Acute Lympho... by Qasim, Waseem, Ciocarlie, Oana, Adams, Stuart, Inglott, Sarah, Murphy, Claire, Rivat, Christine, Wright, Gary, Lucchini, Giovanna, Silva, Juliana, Rao, Kanchan, Zinaï, Amina, Binlich, Florence, Dupouy, Sandra, Pauly, Jeanne, Balandraud, Svetlana, Dubois, Frédéric, Konto, Cyril, Patel, Premal, Chiesa, Robert, Samarasinghe, Sujith, Hara, Havinder, Boyle, Alayna, Chu, Jan, Pinner, Danielle, Amrolia, Persis J, Vora, Ajay, Rao, Anupama, Ancliffe, Philip, Veys, Paul

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First Clinical Application of Talen Engineered Universal CAR19 T Cells in B-ALL by Qasim, Waseem, Amrolia, Persis Jal, Samarasinghe, Sujith, Ghorashian, Sara, Zhan, Hong, Stafford, Sian, Butler, Katie, Ahsan, Gul, Gilmour, Kimberly, Adams, Stuart, Pinner, Danielle, Chiesa, Robert, Chatters, Steve, Swift, Sue, Goulden, Nicholas, Peggs, Karl, Thrasher, Adrian J, Veys, Paul, Pule, Martin

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