Development of a ligand for in vivo imaging of mutant huntingtin in Huntington's disease by Bertoglio, Daniele, Bard, Jonathan, Hessmann, Manuela, Liu, Longbin, Gärtner, Annette, De Lombaerde, Stef, Huscher, Britta, Zajicek, Franziska, Miranda, Alan, Peters, Finn, Herrmann, Frank, Schaertl, Sabine, Vasilkovska, Tamara, Brown, Christopher J, Johnson, Peter D, Prime, Michael E, Mills, Matthew R, Van der Linden, Annemie, Mrzljak, Ladislav, Khetarpal, Vinod, Wang, Yuchuan, Marchionini, Deanna M, Skinbjerg, Mette, Verhaeghe, Jeroen, Dominguez, Celia, Staelens, Steven, Munoz-Sanjuan, Ignacio

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Pharmacological characterization of mutant huntingtin aggregate-directed PET imaging tracer candidates by Herrmann, Frank, Hessmann, Manuela, Schaertl, Sabine, Berg-Rosseburg, Karola, Brown, Christopher J, Bursow, Galina, Chiki, Anass, Ebneth, Andreas, Gehrmann, Miriam, Hoeschen, Nicole, Hotze, Madlen, Jahn, Stefanie, Johnson, Peter D, Khetarpal, Vinod, Kiselyov, Alex, Kottig, Karsten, Ladewig, Stefanie, Lashuel, Hilal, Letschert, Sven, Mills, Matthew R, Petersen, Kathrin, Prime, Michael E, Scheich, Christoph, Schmiedel, Gerhard, Wityak, John, Liu, Longbin, Dominguez, Celia, Muñoz-Sanjuán, Ignacio, Bard, Jonathan A

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Phthalazinone Pyrazoles as Potent, Selective, and Orally Bioavailable Inhibitors of Aurora-A Kinase by Prime, Michael E, Courtney, Stephen M, Brookfield, Frederick A, Marston, Richard W, Walker, Victoria, Warne, Justin, Boyd, Andrew E, Kairies, Norman A, von der Saal, Wolfgang, Limberg, Anja, Georges, Guy, Engh, Richard A, Goller, Bernhard, Rueger, Petra, Rueth, Matthias

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Discovery and Structure–Activity Relationship of Potent and Selective Covalent Inhibitors of Transglutaminase 2 for Huntington’s Disease by Prime, Michael E, Andersen, Ole A, Barker, John J, Brooks, Mark A, Cheng, Robert K. Y, Toogood-Johnson, Ian, Courtney, Stephen M, Brookfield, Frederick A, Yarnold, Christopher J, Marston, Richard W, Johnson, Peter D, Johnsen, Siw F, Palfrey, Jordan J, Vaidya, Darshan, Erfan, Sayeh, Ichihara, Osamu, Felicetti, Brunella, Palan, Shilpa, Pedret-Dunn, Anna, Schaertl, Sabine, Sternberger, Ina, Ebneth, Andreas, Scheel, Andreas, Winkler, Dirk, Toledo-Sherman, Leticia, Beconi, Maria, Macdonald, Douglas, Muñoz-Sanjuan, Ignacio, Dominguez, Celia, Wityak, John

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[ 11 C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins by Liu, Longbin, Johnson, Peter D, Prime, Michael E, Khetarpal, Vinod, Lee, Matthew R, Brown, Christopher J, Chen, Xuemei, Clark-Frew, Daniel, Coe, Samuel, Conlon, Mike, Davis, Randall, Ensor, Samantha, Esposito, Simone, Moren, Anton Forsberg, Gai, Xinjie, Green, Samantha, Greenaway, Catherine, Haber, James, Halldin, Christer, Hayes, Sarah, Herbst, Todd, Herrmann, Frank, Heßmann, Manuela, Hsai, Ming Min, Kotey, Adrian, Mangette, John E, Mills, Matthew R, Monteagudo, Edith, Nag, Sangram, Nibbio, Martina, Orsatti, Laura, Schaertl, Sabine, Scheich, Christoph, Sproston, Joanne, Stepanov, Vladimir, Varnäs, Katarina, Varrone, Andrea, Wityak, John, Mrzljak, Ladislav, Munoz-Sanjuan, Ignacio, Bard, Jonathan A, Dominguez, Celia

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Development of a Series of Aryl Pyrimidine Kynurenine Monooxygenase Inhibitors as Potential Therapeutic Agents for the Treatment of Huntington’s Disease by Toledo-Sherman, Leticia M, Prime, Michael E, Mrzljak, Ladislav, Beconi, Maria G, Beresford, Alan, Brookfield, Frederick A, Brown, Christopher J, Cardaun, Isabell, Courtney, Stephen M, Dijkman, Ulrike, Hamelin-Flegg, Estelle, Johnson, Peter D, Kempf, Valerie, Lyons, Kathy, Matthews, Kimberly, Mitchell, William L, O’Connell, Catherine, Pena, Paula, Powell, Kendall, Rassoulpour, Arash, Reed, Laura, Reindl, Wolfgang, Selvaratnam, Suganathan, Friley, Weslyn Ward, Weddell, Derek A, Went, Naomi E, Wheelan, Patricia, Winkler, Christin, Winkler, Dirk, Wityak, John, Yarnold, Christopher J, Yates, Dawn, Munoz-Sanjuan, Ignacio, Dominguez, Celia

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A versatile, non-biomimetic route to the preussomerins: syntheses of (+/-)-preussomerins F, K and L by Quesada, Ernesto, Stockley, Martin, Ragot, Jacques P, Prime, Michael E, Whitwood, Adrian C, Taylor, Richard J K

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SAR Development of Lysine-Based Irreversible Inhibitors of Transglutaminase 2 for Huntington's Disease by Wityak, John, Prime, Michael E, Brookfield, Frederick A, Courtney, Stephen M, Erfan, Sayeh, Johnsen, Siw, Johnson, Peter D, Li, Marie, Marston, Richard W, Reed, Laura, Vaidya, Darshan, Schaertl, Sabine, Pedret-Dunn, Anna, Beconi, Maria, Macdonald, Douglas, Muñoz-Sanjuan, Ignacio, Dominguez, Celia

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Irreversible 4‑Aminopiperidine Transglutaminase 2 Inhibitors for Huntington's Disease by Prime, Michael E, Brookfield, Frederick A, Courtney, Stephen M, Gaines, Simon, Marston, Richard W, Ichihara, Osamu, Li, Marie, Vaidya, Darshan, Williams, Helen, Pedret-Dunn, Anna, Reed, Laura, Schaertl, Sabine, Toledo-Sherman, Leticia, Beconi, Maria, Macdonald, Douglas, Muñoz-Sanjuan, Ignacio, Dominguez, Celia, Wityak, John

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Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand by Liu, Longbin, Prime, Michael E, Lee, Matt R, Khetarpal, Vinod, Brown, Christopher J, Johnson, Peter D, Miranda-Azpiazu, Patricia, Chen, Xuemei, Clark-Frew, Daniel, Coe, Samuel, Davis, Randall, Dickie, Anthony, Ebneth, Andreas, Esposito, Simone, Gadouleau, Elise, Gai, Xinjie, Galan, Sebastien, Green, Samantha, Greenaway, Catherine, Giles, Paul, Halldin, Christer, Hayes, Sarah, Herbst, Todd, Herrmann, Frank, Heßmann, Manuela, Jia, Zhisheng, Kiselyov, Alexander, Kotey, Adrian, Krulle, Thomas, Mangette, John E, Marston, Richard W, Menta, Sergio, Mills, Matthew R, Monteagudo, Edith, Nag, Sangram, Nibbio, Martina, Orsatti, Laura, Schaertl, Sabine, Scheich, Christoph, Sproston, Joanne, Stepanov, Vladimir, Svedberg, Marie, Takano, Akihiro, Taylor, Malcolm, Thomas, Wayne, Toth, Miklós, Vaidya, Darshan, Vanräs, Katarina, Weddell, Derek, Wigginton, Ian, Wityak, John, Mrzljak, Ladislav, Munoz-Sanjuan, Ignacio, Bard, Jonathan A, Dominguez, Celia

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Design and Evaluation of [18F]CHDI-650 as a Positron Emission Tomography Ligand to Image Mutant Huntingtin Aggregates by Liu, Longbin, Johnson, Peter D., Prime, Michael E., Khetarpal, Vinod, Brown, Christopher J., Anzillotti, Luca, Bertoglio, Daniele, Chen, Xuemei, Coe, Samuel, Davis, Randall, Dickie, Anthony P., Esposito, Simone, Gadouleau, Elise, Giles, Paul R., Greenaway, Catherine, Haber, James, Halldin, Christer, Haller, Scott, Hayes, Sarah, Herbst, Todd, Herrmann, Frank, Heßmann, Manuela, Hsai, Ming Min, Khani, Yaser, Kotey, Adrian, Lembo, Angelo, Mangette, John E., Marriner, Gwendolyn A., Marston, Richard W., Mills, Matthew R., Monteagudo, Edith, Forsberg-Morén, Anton, Nag, Sangram, Orsatti, Laura, Sandiego, Christine, Schaertl, Sabine, Sproston, Joanne, Staelens, Steven, Tookey, Jack, Turner, Penelope A., Vecchi, Andrea, Veneziano, Maria, Muñoz-Sanjuan, Ignacio, Bard, Jonathan, Dominguez, Celia

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A Novel Route to Preussomerins via 2-Arylacetal Anions by Ragot, Jacques P, Prime, Michael E, Archibald, Stephen J, Taylor, Richard J. K

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Concise Syntheses of γ-Oxo-β,β-difluorinated Amino Acids via Chelated [3,3]-Rearrangement of Difluoroallylic Alcohols by Percy, Jonathan M, Prime, Michael E, Broadhurst, Michael J

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Rearrangement routes to selectively fluorinated compounds by Percy, Jonathan M., Prime, Michael E.

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Synthesis of α-hydroxy-β,β-difluoro-γ-ketoesters via [3,3]sigmatropic rearrangements by Broadhurst, Michael J., Brown, Samantha J., Percy, Jonathan M., Prime, Michael E.

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Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Tria... by Oslin, David W, Lynch, Kevin G, Shih, Mei-Chiung, Ingram, Erin P, Wray, Laura O, Chapman, Sara R, Kranzler, Henry R, Gelernter, Joel, Pyne, Jeffrey M, Stone, Annjanette, DuVall, Scott L, Lehmann, Lisa Soleymani, Thase, Michael E, Aslam, Muhammad, Batki, Steven L, Bjork, James M, Blow, Frederic C, Brenner, Lisa A, Chen, Peijun, Desai, Shivan, Dieperink, Eric W, Fears, Scott C, Fuller, Matthew A, Goodman, Courtney S, Graham, David P, Haas, Gretchen L, Hamner, Mark B, Helstrom, Amy W, Hurley, Robin A, Icardi, Michael S, Jurjus, George J, Kilbourne, Amy M, Kreyenbuhl, Julie, Lache, Daniel J, Lieske, Steven P, Lynch, Julie A, Meyer, Laurence J, Montalvo, Cristina, Muralidhar, Sumitra, Ostacher, Michael J, Paschall, Gayla Y, Pfeiffer, Paul N, Prieto, Susana, Przygodzki, Ronald M, Ranganathan, Mohini, Rodriguez-Suarez, Mercedes M, Roggenkamp, Hannah, Schichman, Steven A, Schneeweis, John S, Simonetti, Joseph A, Steinhauer, Stuart R, Suppes, Trisha, Umbert, Maria A, Vassy, Jason L, Voora, Deepak, Wiechers, Ilse R, Wood, Amanda E

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Genomic variability of monkeypox virus among humans, Democratic Republic of the Congo by Kugelman, Jeffrey R, Johnston, Sara C, Mulembakani, Prime M, Kisalu, Neville, Lee, Michael S, Koroleva, Galina, McCarthy, Sarah E, Gestole, Marie C, Wolfe, Nathan D, Fair, Joseph N, Schneider, Bradley S, Wright, Linda L, Huggins, John, Whitehouse, Chris A, Wemakoy, Emile Okitolonda, Muyembe-Tamfum, Jean Jacques, Hensley, Lisa E, Palacios, Gustavo F, Rimoin, Anne W

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Measurement of H2O2 within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix by Cochemé, Helena M., Quin, Caroline, McQuaker, Stephen J., Cabreiro, Filipe, Logan, Angela, Prime, Tracy A., Abakumova, Irina, Patel, Jigna V., Fearnley, Ian M., James, Andrew M., Porteous, Carolyn M., Smith, Robin A.J., Saeed, Saima, Carré, Jane E., Singer, Mervyn, Gems, David, Hartley, Richard C., Partridge, Linda, Murphy, Michael P.

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Accelerating the Evolution of Nonhuman Primate Neuroimaging by Milham, Michael, Basso, Michele A., Belin, Pascal, Fair, Damien A., Kastner, Sabine, Mars, Rogier B., Messinger, Adam, Poirier, Colline, Vanduffel, Wim, Becker, Yannick, Ben Hamed, Suliann, Benn, Austin, Bodin, Clementine, Boretius, Susann, Cagna, Bastien, Coulon, Olivier, El-Gohary, Sherif Hamdy, Forkel, Stephanie J., Froudist-Walsh, Sean, Gao, Yang, Gozzi, Alessandro, Grigis, Antoine, Hayashi, Takuya, Heuer, Katja, Howells, Henrietta, Jarraya, Béchir, Jedema, Hank P., Kelly, Clare, Kennedy, Henry, Leech, Robert, Madan, Christopher, Mallon, Ann-Marie, Marche, Kevin, Meguerditchian, Adrien, Menon, Ravi S., Merchant, Hugo, Mitchell, Anna, Nenning, Karl-Heinz, Nikolaidis, Aki, Ortiz-Rios, Michael, Pareek, Vikas, Prescott, Mark, Rajimehr, Reza, Rautu, Ioana-Sabina, Raz, Amir, Roe, Anna Wang, Rossi-Pool, Román, Roumazeilles, Lea, Sallet, Jerome, García-Saldivar, Pamela, Sawiak, Stephen, Seidlitz, Jakob, Shen, Zhi-ming, Shmuel, Amir, Silva, Afonso C., Sirmpilatze, Nikoloz, Sliwa, Julia, Smallwood, Jonathan, Tasserie, Jordy, Thiebaut de Schotten, Michel, Toro, Roberto, Uhrig, Lynn, Williams, Bella, Xu, Augix Guohua, Zhan, Ming, Ai, Lei, Balezeau, Fabien, Baxter, Mark G., Blezer, Erwin L.A., Chen, Aihua, Croxson, Paula L., Damatac, Christienne G., Dehaene, Stanislas, Everling, Stefan, Fleysher, Lazar, Griffiths, Timothy D., Guedj, Carole, Hadj-Bouziane, Fadila, Harel, Noam, Hiba, Bassem, Jung, Benjamin, Koo, Bonhwang, Laland, Kevin N., Leopold, David A., Lindenfors, Patrik, Mok, Kelvin, Pinsk, Mark, Reader, Simon M., Roelfsema, Pieter R., Rushworth, Matthew F.S., Russ, Brian E., Schmid, Michael Christoph, Thiele, Alexander, Todorov, Orlin S., Tsao, Doris, Ungerleider, Leslie, Wilson, Charles R.E., Ye, Frank Q., Zarco, Wilbert, Zhou, Yong-di

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The mitochondria-targeted anti-oxidant MitoQ reduces aspects of mitochondrial fission in the 6-OHDA cell model of Parkinson's disease by Solesio, María E., Prime, Tracy A., Logan, Angela, Murphy, Michael P., del Mar Arroyo-Jimenez, María, Jordán, Joaquín, Galindo, María F.

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