GLPG0187 inhibits progression of established bone metastasis and achieves maximum efficacy when combined with standard-of-care metastatic breast cancer treatments by Clément-Lacroix, P, Berrocal, E, Heckmann, B, Wigerinck, P, Lorenzon, G, Pujuguet, P

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PP 87 Molecular imaging demonstrates GLPG0187, a small-molecule integrin antagonist, binds to RGD-integrin receptors in vivo and is efficacious in tumor and metastasis models by Pujuguet, P, Berrocal, E, Heckmann, B, Wigerinck, P, Lorenzon, G, Clément-Lacroix, P, Bormans, G, Deroose, C

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Role of Stromal Myofibroblasts Infiltrating Colon Cancer in Tumor Invasion by Martin, M., Pujuguet, P., Martin, F.

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Ezrin regulates E-cadherin-dependent adherens junction assembly through Rac1 activation by Pujuguet, Philippe, Del Maestro, Laurence, Gautreau, Alexis, Louvard, Daniel, Arpin, Monique

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Pharmacological inhibition of the medium chain fatty acid receptor GPR84 reduces myeloid cell in filtration into injured liver and ameliorates steatohepatitis and fibrosis by Puengel, T., De Vos, S., Krenkel, O., Pujuguet, P., Auberval, M., Marsais, F., Shoji, K.F., Saniere, L., Trautwein, C., Brys, R., Tacke, F.

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THU-461 - Pharmacological inhibition of the medium chain fatty acid receptor GPR84 reduces myeloid cell in filtration into injured liver and ameliorates steatohepatitis and fibrosi... by Puengel, T., De Vos, S., Krenkel, O., Pujuguet, P., Auberval, M., Marsais, F., Shoji, K.F., Saniere, L., Trautwein, C., Brys, R., Tacke, F.

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Molecular imaging demonstrates GLPG0187, a small-molecule integrin antagonist, binds to RGD-integrin receptors in vivo and is efficacious in tumor and metastasis models by Pujuguet, P, Berrocal, E, Heckmann, B, Wigerinck, P, Lorenzon, G, Clement-Lacroix, P, Bormans, G, Deroose, C

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Targeting of alphav integrins in stem/progenitor cells and supportive microenvironment impairs bone metastasis in human prostate cancer by van der Horst, G, van den Hoogen, C, Buijs, J T, Cheung, H, Bloys, H, Pelger, RCM, Lorenzon, G, Heckmann, B, Feyen, J, Pujuguet, P, Blanque, R, Clement-Lacroix, P, van der Pluijm, G

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Characterization of BCE-1, a Transcriptional Enhancer Regulated by Prolactin and Extracellular Matrix and Modulated by the State of Histone Acetylation by Myers, Connie A., Schmidhauser, Christian, Mellentin-Michelotti, Julia, Fragoso, Gilberto, Roskelley, Calvin D., Casperson, Gerald, Mossi, Romina, Pujuguet, Philippe, Hager, Gordon, Bissell, Mina J.

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Trichostatin a inhibits β-casein expression in mammary epithelial cells by Pujuguet, Philippe, Radisky, Derek, Levy, Dinah, Lacza, Charlemagne, Bissell, Mina J.

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A 24‐Week, Phase IIa, Randomized, Double‐Blind, Placebo‐Controlled Study of Ziritaxestat in Early Diffuse Cutaneous Systemic Sclerosis by Khanna, Dinesh, Denton, Christopher P., Furst, Daniel E., Mayes, Maureen D., Matucci‐Cerinic, Marco, Smith, Vanessa, Vries, Dick, Ford, Paul, Bauer, Yasmina, Randall, Matthew J., Ebrahimpoor, Mitra, Kupcsik, Laszlo, Stiers, Pieter‐Jan, Deberdt, Liesbeth, Prasad, Niyati, Lim, Sharlene, Pujuguet, Philippe, Ahmed, Sohail

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Pharmacological targeting of the ephrin receptor kinase signalling by GLPG1790 in vitro and in vivo reverts oncophenotype, induces myogenic differentiation and radiosensitizes embr... by Megiorni, Francesca, Gravina, Giovanni Luca, Camero, Simona, Ceccarelli, Simona, Del Fattore, Andrea, Desiderio, Vincenzo, Papaccio, Federica, McDowell, Heather P, Shukla, Rajeev, Pizzuti, Antonio, Beirinckx, Filip, Pujuguet, Philippe, Saniere, Laurent, der Aar, Ellen Van, Maggio, Roberto, De Felice, Francesca, Marchese, Cinzia, Dominici, Carlo, Tombolini, Vincenzo, Festuccia, Claudio, Marampon, Francesco

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A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignanci... by Cirkel, Geert A., Kerklaan, Bojana Milojkovic, Vanhoutte, Frédéric, der Aa, Annegret Van, Lorenzon, Giocondo, Namour, Florence, Pujuguet, Philippe, Darquenne, Sophie, de Vos, Filip Y. F., Snijders, Tom J., Voest, Emile E., Schellens, Jan H. M., Lolkema, Martijn P.

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