PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer by Raina, Kanak, Lu, Jing, Qian, Yimin, Altieri, Martha, Gordon, Deborah, Rossi, Ann Marie K., Wang, Jing, Chen, Xin, Dong, Hanqing, Siu, Kam, Winkler, James D., Crew, Andrew P., Crews, Craig M., Coleman, Kevin G.

Get full text

Design and SAR of thienopyrimidine and thienopyridine inhibitors of VEGFR-2 kinase activity by Munchhof, Michael J., Beebe, Jean S., Casavant, Jeffery M., Cooper, Beth A., Doty, Jonathan L., Higdon, R.Carla, Hillerman, Stephen M., Soderstrom, Catherine I., Knauth, Elisabeth A., Marx, Matthew A., Rossi, Ann Marie K., Sobolov, Susan B., Sun, Jianmin

Get full text

Discovery and pharmacologic characterization of CP-724,714, a selective ErbB2 tyrosine kinase inhibitor by JANI, Jitesh P, FINN, Richard S, MORRIS, Joel, MOYER, James D, PUSTILNIK, Leslie R, RAFIDI, Kristina, RALSTON, Sherry, ROSSI, Ann Marie K, STEYN, Stefanus J, WAGNER, Larry, WINTER, Steven M, BHATTACHARYA, Samit K, CAMPBELL, Mary, COLEMAN, Kevin G, CONNELL, Richard D, CURRIER, Nicolas, EMERSON, Erling O, FLOYD, Eugenia, HARRIMAN, Shawn, KATH, John C

Get full text

The biological and biochemical effects of CP-654577, a selective erbB2 kinase inhibitor, on human breast cancer cells by BARBACCI, E. Gabriella, PUSTILNIK, Leslie R, KATH, John C, ZHENGYU LIU, MOYER, James D, ROSSI, Ann Marie K, EMERSON, Erling, MILLER, Penny E, BOSCOE, Brian P, COX, Eric D, IWATA, Kenneth K, JANI, Jitesh P, PROVONCHA, Kathleen

Get full text

The CIP2A-TOPBP1 complex safeguards chromosomal stability during mitosis by De Marco Zompit, Mara, Esteban, Mònica Torres, Mooser, Clémence, Adam, Salomé, Rossi, Silvia Emma, Jeanrenaud, Alain, Leimbacher, Pia-Amata, Fink, Daniel, Shorrocks, Ann-Marie K., Blackford, Andrew N., Durocher, Daniel, Stucki, Manuel

Get full text

The Dark Energy Spectroscopic Instrument: one-dimensional power spectrum from first Ly α forest samples with Fast Fourier Transform by Ravoux, Corentin, Abdul Karim, Marie Lynn, Armengaud, Eric, Walther, Michael, Karaçaylı, Naim Göksel, Martini, Paul, Guy, Julien, Aguilar, Jessica Nicole, Ahlen, Steven, Bailey, Stephen, Bautista, Julian, Beltran, Sergio Felipe, Brooks, David, Cabayol-Garcia, Laura, Chabanier, Solène, Chaussidon, Edmond, Chaves-Montero, Jonás, Dawson, Kyle, de la Cruz, Rodrigo, de la Macorra, Axel, Doel, Peter, Fanning, Kevin, Font-Ribera, Andreu, Forero-Romero, Jaime, Gontcho A Gontcho, Satya, Gonzalez-Morales, Alma X, Gordon, Calum, Herrera-Alcantar, Hiram K, Honscheid, Klaus, Iršič, Vid, Ishak, Mustapha, Kehoe, Robert, Kisner, Theodore, Kremin, Anthony, Landriau, Martin, Le Guillou, Laurent, Levi, Michael, Lukić, Zarija, Magneville, Christophe, Meisner, Aaron, Miquel, Ramon, Moustakas, John, Mueller, Eva-Maria, Muñoz-Gutiérrez, Andrea, Napolitano, Lucas, Nie, Jundan, Niz, Gustavo, Palanque-Delabrouille, Nathalie, Percival, Will, Pérez-Ràfols, Ignasi, Pieri, Matthew, Poppett, Claire, Prada, Francisco, Ramírez Pérez, César, Rossi, Graziano, Sanchez, Eusebio, Schlegel, David, Schubnell, Michael, Seo, Hee-Jong, Sinigaglia, Francesco, Tan, Ting, Tarlé, Gregory, Wang, Ben, Weaver, Benjamin, Yèche, Christophe, Zhou, Zhimin

Get full text

Insulin-like growth factor binding protein-2 in at-risk adults and autopsy-confirmed Alzheimer brains by Quesnel, Marc James, Labonté, Anne, Picard, Cynthia, Zetterberg, Henrik, Blennow, Kaj, Brinkmalm, Ann, Villeneuve, Sylvia, Poirier, Judes

Get full text

Harmonizing neuropsychological assessment for mild neurocognitive disorders in Europe by Boccardi, Marina, Monsch, Andreas, Ferrari, Clarissa, Altomare, Daniele, Berres, Manfred, Bos, Isabelle, Buchmann, Andreas, Cerami, Chiara, Didic, Mira, Festari, Cristina, Nicolosi, Valentina, Sacco, Leonardo, Aerts, Liesbeth, Albanese, Emiliano, Annoni, Jean‐marie, Ballhausen, Nicola, Chicherio, Christian, Démonet, Jean‐françois, Descloux, Virginie, Diener, Suzie, Ferreira, Daniel, Georges, Jean, Gietl, Anton, Girtler, Nicola, Kilimann, Ingo, Klöppel, Stefan, Kustyniuk, Nicole, Mecocci, Patrizia, Mella, Nathalie, Pigliautile, Martina, Seeher, Katrin, Shirk, Steven, Toraldo, Alessio, Brioschi‐guevara, Andrea, Chan, Kwun, Crane, Paul, Dodich, Alessandra, Grazia, Alice, Kochan, Nicole, Oliveira, Fabricio Ferreira, Nobili, Flavio, Kukull, Walter, Peters, Oliver, Ramakers, Inez, Sachdev, Perminder, Teipel, Stefan, Visser, Pieter Jelle, Wagner, Michael, Weintraub, Sandra, Westman, Eric, Froelich, Lutz, Brodaty, Henry, Dubois, Bruno, Cappa, Stefano, Salmon, David, Winblad, Bengt, Frisoni, Giovanni, Kliegel, Matthias

Get full text

PF-03814735, an orally bioavailable small molecule aurora kinase inhibitor for cancer therapy by Jani, Jitesh P, Arcari, Joel, Bernardo, Vincent, Bhattacharya, Samit K, Briere, David, Cohen, Bruce D, Coleman, Kevin, Christensen, James G, Emerson, Erling O, Jakowski, Amy, Hook, Kenneth, Los, Gerrit, Moyer, James D, Pruimboom-Brees, Ingrid, Pustilnik, Leslie, Rossi, Ann Marie, Steyn, Stefan J, Su, Chunyan, Tsaparikos, Konstantinos, Wishka, Donn, Yoon, Kwansik, Jakubczak, John L

Get full text

Identification of genes required for eye development by high-throughput screening of mouse knockouts by Moore, Bret A., Leonard, Brian C., Sebbag, Lionel, Edwards, Sydney G., Cooper, Ann, Imai, Denise M., Straiton, Ewan, Santos, Luis, Reilly, Christopher, Griffey, Stephen M., Bower, Lynette, Clary, David, Mason, Jeremy, Roux, Michel J., Meziane, Hamid, Herault, Yann, McKerlie, Colin, Flenniken, Ann M., Nutter, Lauryl M. J., Berberovic, Zorana, Owen, Celeste, Newbigging, Susan, Adissu, Hibret, Eskandarian, Mohammed, Hsu, Chih-Wei, Kalaga, Sowmya, Udensi, Uchechukwu, Asomugha, Chinwe, Bohat, Ritu, Gallegos, Juan J., Seavitt, John R., Heaney, Jason D., Beaudet, Arthur L., Dickinson, Mary E., Justice, Monica J., Philip, Vivek, Kumar, Vivek, Svenson, Karen L., Braun, Robert E., Wells, Sara, Cater, Heather, Stewart, Michelle, Clementson-Mobbs, Sharon, Joynson, Russell, Gao, Xiang, Suzuki, Tomohiro, Wakana, Shigeharu, Smedley, Damian, Seong, J. K, Tocchini-Valentini, Glauco, Moore, Mark, Fletcher, Colin, Karp, Natasha, Ramirez-Solis, Ramiro, White, Jacqueline K., de Angelis, Martin Hrabe, Wurst, Wolfgang, Thomasy, Sara M., Flicek, Paul, Parkinson, Helen, Brown, Steve D. M., Meehan, Terrence F., Nishina, Patsy M., Murray, Stephen A., Krebs, Mark P., Mallon, Ann-Marie, Lloyd, K. C. Kent, Murphy, Christopher J., Moshiri, Ala

Get full text

Pharmacological characterization of CP-547,632, a novel vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for cancer therapy by Beebe, Jean S, Jani, Jitesh P, Knauth, Elisabeth, Goodwin, Peter, Higdon, Carla, Rossi, Ann Marie, Emerson, Erling, Finkelstein, Martin, Floyd, Eugenia, Harriman, Shawn, Atherton, Jim, Hillerman, Steve, Soderstrom, Cathy, Kou, Kou, Gant, Tom, Noe, Mark C, Foster, Barb, Rastinejad, Farzan, Marx, Matthew A, Schaeffer, Tracey, Whalen, Pamela M, Roberts, W Gregory

Get full text