Quantitative pharmacological analysis of antagonist binding kinetics at CRF1 receptors in vitro and in vivo by Ramsey, Simeon J, Attkins, Neil J, Fish, Rebecca, van der Graaf, Piet H

Get full text

The Interleukin‐1 Receptor–Associated Kinase 4 Inhibitor PF‐06650833 Blocks Inflammation in Preclinical Models of Rheumatic Disease and in Humans Enrolled in a Randomized Clinical... by Winkler, Aaron, Sun, Weiyong, De, Saurav, Jiao, Aiping, Sharif, M. Nusrat, Symanowicz, Peter T., Athale, Shruti, Shin, Julia H., Wang, Ju, Jacobson, Bruce A., Ramsey, Simeon J., Dower, Ken, Andreyeva, Tatyana, Liu, Heng, Hegen, Martin, Homer, Bruce L., Brodfuehrer, Joanne, Tilley, Mera, Gilbert, Steven A., Danto, Spencer I., Beebe, Jean J., Barnes, Betsy J., Pascual, Virginia, Lin, Lih‐Ling, Kilty, Iain, Fleming, Margaret, Rao, Vikram R.

Get full text

Quantitative pharmacological analysis of antagonist binding kinetics at CRF 1 receptors in vitro and in vivo by Ramsey, Simeon J, Attkins, Neil J, Fish, Rebecca, van der Graaf, Piet H

Get full text

Correction: Design and chemoproteomic functional characterization of a chemical probe targeted to bromodomains of BET family proteins by Wu, Jiang, Shin, Julia, Williams, Cara M. M, Geoghegan, Kieran F, Wright, Stephen W, Limburg, David C, Sahasrabudhe, Parag, Bonin, Paul D, Lefker, Bruce A, Ramsey, Simeon J

Get full text

Quantitative pharmacological analysis of antagonist binding kinetics at CRF, receptors in vitro and in vivo by RAMSEY, Simeon J, ATTKINS, Neil J, FISH, Rebecca, VAN DER GRAAF, Piet H

Get full text

Design and chemoproteomic functional characterization of a chemical probe targeted to bromodomains of BET family proteins by Wu, Jiang, Shin, Julia, Williams, Cara M. M., Geoghegan, Kieran F., Wright, Stephen W., Limburg, David C., Sahasrabudhe, Parag, Bonin, Paul D., Lefker, Bruce A., Ramsey, Simeon J.

Get full text

Design and chemoproteomic functional characterization of a chemical probe targeted to bromodomains of BET family proteinsElectronic supplementary information (ESI) available: Detai... by Wu, Jiang, Shin, Julia, Williams, Cara M. M, Geoghegan, Kieran F, Wright, Stephen W, Limburg, David C, Sahasrabudhe, Parag, Bonin, Paul D, Lefker, Bruce A, Ramsey, Simeon J

Get full text

Discovery, Characterization, and Structure of a Cell Active PAD2 Inhibitor Acting through a Novel Allosteric Mechanism by Byrnes, Laura J., Choi, Won Young, Balbo, Paul, Banker, Mary Ellen, Chang, Jeanne, Chen, Shi, Cheng, Xuemin, Cong, Yang, Culp, Jeff, Di, Hongxia, Griffor, Matt, Hall, Justin, Meng, Xiaoyun, Morgan, Barry, Mousseau, James J., Nicki, Jennifer, O’Connell, Thomas, Ramsey, Simeon, Shaginian, Alex, Shanker, Suman, Trujillo, John, Wan, Jinqiao, Vincent, Fabien, Wright, Stephen W., Vajdos, Felix

Get full text

Design and Synthesis of γ- and δ‑Lactam M1 Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M1‑Selective PAM with Weak Agonist Activity by Davoren, Jennifer E, Garnsey, Michelle, Pettersen, Betty, Brodney, Michael A, Edgerton, Jeremy R, Fortin, Jean-Philippe, Grimwood, Sarah, Harris, Anthony R, Jenkinson, Stephen, Kenakin, Terry, Lazzaro, John T, Lee, Che-Wah, Lotarski, Susan M, Nottebaum, Lisa, O’Neil, Steven V, Popiolek, Michael, Ramsey, Simeon, Steyn, Stefanus J, Thorn, Catherine A, Zhang, Lei, Webb, Damien

Get full text

Design and Synthesis of γ- and δ-Lactam M 1 Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M 1 -Selective PAM with Weak Agonist Activity by Davoren, Jennifer E, Garnsey, Michelle, Pettersen, Betty, Brodney, Michael A, Edgerton, Jeremy R, Fortin, Jean-Philippe, Grimwood, Sarah, Harris, Anthony R, Jenkinson, Stephen, Kenakin, Terry, Lazzaro, John T, Lee, Che-Wah, Lotarski, Susan M, Nottebaum, Lisa, O'Neil, Steven V, Popiolek, Michael, Ramsey, Simeon, Steyn, Stefanus J, Thorn, Catherine A, Zhang, Lei, Webb, Damien

Get full text

In vitro and in vivo pharmacological characterisation of the potent and selective vasopressin V(1A) receptor antagonist 4-[4-(4-Chloro-phenyl)-5-[1,2,3]triazol-2-ylmethyl-4H-[1,2,4... by Russell, Rachel, Doyle, Rachel, Turner, Jamie, Attkins, Neil, Ramsey, Simeon, Weibley, Laura, Bateman, Lucy, Bictash, Magda, Neal-Morgan, Stevie, Ivarsson, Magnus, Pullen, Nick

Get full text