Combined JAK/STAT5A and BCR-ABL Inhibition Impairs Blast Crisis Chronic Myeloid Leukemia Stem Cell Self-Renewal by Recart, Angela C Court, Goff, Daniel J, Sadarangani, Anil, Mason, Cayla N, Shih, Alice Y., Wall, Russell, Leu, Heather S., Ma, Wenxue, Chun, Hye-Jung, Marra, Marco A., Barrett, Christian L, Frazer, Kelly A, Jamieson, Catriona

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Inhibition Of Inflammation Driven Leukemia Stem Cell Self-Renewal With a Selective JAK2 Antagonist by Court Recart, Angela C, Sadarangani, Anil, Chun, Elizabeth, Mason, Cayla N, Jiang, Qingfei, Barrett, Christian L, Wall, Russell, Goff, Daniel J, Geron, Ifat, Shih, Alice, Leu, Heather S., Ma, Wenxue, Minden, Mark D., Frazer, Kelly A, Marra, Marco A., Crews, Leslie A, Jamieson, Catriona HM

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Sabutoclax, a Novel Pan BCL2 Family Inhibitor, Sensitizes Dormant Blast Crisis Chronic Myeloid Leukemia Stem Cells to Dasatinib by Leu, Heather S., Goff, Daniel J, Low-Marchelli, Janine, Recart, Angela C Court, Smith, Kristen M., Ma, Wenxue, Sadarangani, Anil, Shih, Alice Y., Wei, Jun, Zhai, Dayong, Gotlib, Jason, Minden, Mark D., Martinelli, Giovanni, Marra, Marco A., Frazer, Kelly A, Pellecchia, Maurizio, Reed, John C., Jamieson, Catriona

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NOTCH1 Signaling Defines a Leukemia Initiating Cell Population in T-Cell Acute Lymphoblastic Leukemia by Ma, Wenxue, Smith, Kristen M., Gutierrez, Alejandro, Leu, Heather S., Jiang, Qingfei, Wu, Christina C.N., Shih, Alice Y., Court-Recart, Angela C., Sadarangani, Anil, Goff, Daniel J., Wei, Ping, Look, A. Thomas, Jamieson, Catriona H.M.

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Combination Targeted Therapy to Impair Self-Renewal Capacity of Human Blast Crisis Leukemia Stem Cells by Court Recart, Angela C, Sadarangani, Anil, Goff, Daniel, Shih, Alice Y, Wall, Russell, Leu, Heather, Ma, Wenxue, Barrett, Christian L, Frazer, Kelly A, Chun, Elizabeth, Marra, Marco A., Jamieson, Catriona

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The RNA Editase ADAR1 Promotes Malignant Progenitor Reprogramming in Chronic Myeloid Leukemia by Jiang, Qingfei, Crews-Robertson, Leslie, Barrett, Christian L, Chun, Hyn-June, Court-Recart, Angela C., Goff, Daniel J, Minden, Mark D., Sadarangani, Anil, Rusert, Jessica, Dao, Kim-Hien, Morris, Sheldon R, Goldstein, Lawrence S.B., Marra, Marco A., Frazer, Kelly A, Jamieson, Catriona

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Cycling Toward Leukemia Stem Cell Elimination Wtih a Selective Sonic Hedgehog Antagonist by Shih, Alice Y, Schairer, Annelie, Barrett, Christian L, Geron, Ifat, Recart, Angela C Court, Goff, Daniel, Prashad, Sacha, Wu, Jerry, Jiang, Qingfei, Gotlib, Jason, Balaian, Larisa, Minden, Mark D., Leu, Heather, Wall, Russell, Ma, Wenxue, Shazand, Kamran, McPherson, John D, Kornblau, Steven M., Deichaite, Ida, Pu, Minya, Bao, Lei, Martinelli, Giovanni, Reya, Tannishtha, Morris, Sheldon R, VanArsdale, Todd, Hudson, Thomas J, Messer, Karen, Mikkola, Hanna, Levin, Wendy J., Frazer, Kelly A, Sadarangani, Anil, Jamieson, Catriona

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A Pan-BCL2 Inhibitor Renders Bone-Marrow-Resident Human Leukemia Stem Cells Sensitive to Tyrosine Kinase Inhibition by Goff, Daniel J., Recart, Angela Court, Sadarangani, Anil, Chun, Hye-Jung, Barrett, Christian L., Krajewska, Maryla, Leu, Heather, Low-Marchelli, Janine, Ma, Wenxue, Shih, Alice Y., Wei, Jun, Zhai, Dayong, Geron, Ifat, Pu, Minya, Bao, Lei, Chuang, Ryan, Balaian, Larisa, Gotlib, Jason, Minden, Mark, Martinelli, Giovanni, Rusert, Jessica, Dao, Kim-Hien, Shazand, Kamran, Wentworth, Peggy, Smith, Kristen M., Jamieson, Christina A.M., Morris, Sheldon R., Messer, Karen, Goldstein, Lawrence S.B., Hudson, Thomas J., Marra, Marco, Frazer, Kelly A., Pellecchia, Maurizio, Reed, John C., Jamieson, Catriona H.M.

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Abstract 217: BCR-ABL tyrosine kinase inhibition combined with a novel pan BCL2 family inhibitor abrogates leukemia stem cell survival in a niche-dependent manner by Ma, Wenxue, Low-Marchelli, Janine, Leu, Heather S., Court Recart, Angela, Wei, Jun, Huang, Xianshu, Krajewska, Maryla, Pellecchia, Maurizio, Reed, John C., Jamieson, Catriona H.M.

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Abstract 974: A selective Notch1 mAb targets leukemia progenitor cells in T-ALL by Ma, Wenxue, Gutierrez, Alejandro, Goff, Daniel, Geron, Ifat, Sadarangani, Anil, Shih, Alice, Recart, Angela Court, Jiang, Qingfei, Wu, Jerry C., Wu, Christina C., Leu, Heather, Wall, Russell, Geyrozaga, Rhonnie, Diccianni, Mitchell, Li, Kang, VanArsdale, Todd, Wei, Ping, Carson, Dennis, Look, A. Thomas, Jamieson, Catriona

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BCL2 Splice Isoform Switching Promotes Leukemia Stem Cell Survival and Sensitivity to a Novel Pan BCL2 Inhibitor by Goff, Daniel, Smith, Kristen M, Shih, Alice Y, Court-Recart, Angela, Sadarangani, Anil, Geron, Ifat, Chuang, Ryan, Balaian, Larisa, Wei, Jun, Kitada, Shinichi, Zhai, Dayong, Gotlib, Jason, Minden, Mark D., Martinelli, Giovanni, Schairer, Annelie, Leu, Heather, Ma, Wenxue, Jiang, Qingfei, Rusert, Jessica, Dao, Kim-Hien T, Shazand, Kamran, Volar, Milica, de Borja, Richard, McPherson, John D, Hudson, Thomas J, Barrett, Christian L, Frazer, Kelly A, Wentworth, Peggy, Jamieson, Christina, Morris, Sheldon R, Goldstein, Lawrence S.B., Pellechia, Maurizio, Reed, John C., Jamieson, Catriona

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