A plasmid system for optimization of Fab ′ production in Escherichia coli: importance of balance of heavy chain and light chain synthesis by Humphreys, David P, Carrington, Bruce, Bowering, Leigh C, Ganesh, Ravindra, Sehdev, Mukesh, Smith, Bryan J, King, Lloyd M, Reeks, Dominic G, Lawson, Alastair, Popplewell, Andrew G

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Recommendations for procurement of starting materials by apheresis for advanced therapy medicinal products by Manson, Lynn, Barry, Jacqueline, Fong, Chris, Potok, Davina, Sweeny, Di, Reeks, Dominic, Watson, Douglas, Hope, Drew, Piccinini, Elia, Cui, Haili, Keane, Helen, Armstrong, Jennifer, Sinclair, Joy, Guest, Julie, Chuku, Justina, Kerr, Maria, Francis, Natalie, Bell, Neil, Smith, Richard, Angelica, Rita, Shingler, William, Shingleton, William, Turner, Marc

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Fedbatch design for periplasmic product retention in Escherichia coli by Bäcklund, Emma, Reeks, Dominic, Markland, Katrin, Weir, Neil, Bowering, Leigh, Larsson, Gen

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Formation of dimeric Fabs in Escherichia coli: effect of hinge size and isotype, presence of interchain disulphide bond, Fab′ expression levels, tail piece sequences and growth con... by Humphreys, David P, Chapman, Andrew P, Reeks, Dominic G, Lang, Volker, Stephens, Paul E

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High-Level Periplasmic Expression in Escherichia coli Using a Eukaryotic Signal Peptide: Importance of Codon Usage at the 5′ End of the Coding Sequence by Humphreys, David P., Sehdev, Mukesh, Chapman, Andrew P., Ganesh, Ravindra, Smith, Bryan J., King, Lloyd M., Glover, David J., Reeks, Dominic G., Stephens, Paul E.

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F(ab′) 2 molecules made from Escherichia coli produced Fab′ with hinge sequences conferring increased serum survival in an animal model by Humphreys, David P., Vetterlein, Olivia M., Chapman, Andrew P., King, David J., Antoniw, Pari, Suitters, Amanda J., Reeks, Dominic G., Parton, Ted A.H., King, Lloyd M., Smith, Bryan J., Lang, Volker, Stephens, Paul E.

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Efficient site specific removal of a C-terminal FLAG fusion from a Fab′ using copper(II) ion catalysed protein cleavage by Humphreys, David P., Smith, Bryan J., King, Lloyd M., West, Shauna M., Reeks, Dominic G., Stephens, Paul E.

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Fragment-Based Discovery of a Novel, Brain Penetrant, Orally Active HDAC2 Inhibitor by Tamanini, Emiliano, Miyamura, Shin, Buck, Ildiko M., Cons, Benjamin D., Dawson, Lee, East, Charlotte, Futamura, Takashi, Goto, Shintaro, Griffiths-Jones, Charlotte, Hashimoto, Tetsuya, Heightman, Tom D., Ishikawa, Shunpei, Ito, Hideki, Kaneko, Yosuke, Kawato, Tatsuya, Kondo, Kazumi, Kurihara, Naoki, McCarthy, James M., Mori, Yukiko, Nagase, Tsuyoshi, Nakaishi, Yuichiro, Reeks, Judith, Sato, Akimasa, Schöpf, Patrick, Tai, Kuninori, Tamai, Taichi, Tisi, Dominic, Woolford, Alison J.-A.

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Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β‑Glucocerebrosidase by Palmer, Nick, Agnew, Christopher, Benn, Caroline, Buffham, William J., Castro, Joan N., Chessari, Gianni, Clark, Mellissa, Cons, Benjamin D., Coyle, Joseph E., Dawson, Lee A., Hamlett, Christopher C. F., Hodson, Charlotte, Holding, Finn, Johnson, Christopher N., Liebeschuetz, John W., Mahajan, Pravin, McCarthy, James M., Murray, Christopher W., O’Reilly, Marc, Peakman, Torren, Price, Amanda, Rapti, Magdalini, Reeks, Judith, Schöpf, Patrick, St-Denis, Jeffrey D., Valenzano, Chiara, Wallis, Nicola G., Walser, Reto, Weir, Heather, Wilsher, Nicola E., Woodhead, Andrew, Bento, Carla F., Tisi, Dominic

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