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Using Human Serum Albumin Binding Affinities as a Proactive Strategy to Affect the Pharmacodynamics and Pharmacokinetics of Preclinical Drug Candidates
by
Fan, Jianwei
,
Gilmartin, Katherine
,
Octaviano, Steven
,
Villar, Francisca
,
Remache, Brianna
,
Regan, John
Published in
ACS pharmacology & translational science
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Synthesis and biological evaluation of orally active prodrugs and analogs of para-aminosalicylic acid (PAS)
by
Hegde, Pooja V.
,
Howe, Michael D.
,
Zimmerman, Matthew D.
,
Boshoff, Helena I.M.
,
Sharma, Sachin
,
Remache, Brianna
,
Jia, Ziyi
,
Pan, Yan
,
Baughn, Anthony D.
,
Dartois, Veronique
,
Aldrich, Courtney C.
Published in
European journal of medicinal chemistry
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Acs Pharmacology & Translational Science
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European Journal Of Medicinal Chemistry
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Subjects
Chemistry, Medicinal
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Life Sciences & Biomedicine
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Pharmacology & Pharmacy
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Science & Technology
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Aminosalicylic Acid - Adverse Effects
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Animals
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Antitubercular Agents - Pharmacology
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Antitubercular Agents - Therapeutic Use
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Binding Affinity
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Biological Availability
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Drug Scaffold
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Fluorination
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Hsa
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Metabolism
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Mice
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N-Acetyltransferase
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Para-Aminosalicylic Acid
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Pharmacodynamics
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Pharmacokinetics
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Prodrug
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American Chemical Society:jisc Collections:american Chemical Society Read & Publish Agreement 2022-2024 (Reading List)
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Elsevier Sciencedirect Journals
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Elsevier
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Pubmed Central Free
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Backfile Package - Organic Chemistry (Legacy) [Yco]
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