Diversity of CFTR variants across ancestries characterized using 454,727 UK biobank whole exome sequences by Ideozu, Justin E, Liu, Mengzhen, Riley-Gillis, Bridget M, Paladugu, Sri R, Rahimov, Fedik, Krishnan, Preethi, Tripathi, Rakesh, Dorr, Patrick, Levy, Hara, Singh, Ashvani, Waring, Jeffrey F, Vasanthakumar, Aparna

Get full text

Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes by Karczewski, Konrad J., Solomonson, Matthew, Chao, Katherine R., Goodrich, Julia K., Tiao, Grace, Lu, Wenhan, Riley-Gillis, Bridget M., Tsai, Ellen A., Kim, Hye In, Zheng, Xiuwen, Rahimov, Fedik, Esmaeeli, Sahar, Grundstad, A. Jason, Reppell, Mark, Waring, Jeff, Jacob, Howard, Sexton, David, Bronson, Paola G., Chen, Xing, Hu, Xinli, Goldstein, Jacqueline I., King, Daniel, Vittal, Christopher, Poterba, Timothy, Palmer, Duncan S., Churchhouse, Claire, Howrigan, Daniel P., Zhou, Wei, Watts, Nicholas A., Nguyen, Kevin, Nguyen, Huy, Mason, Cara, Farnham, Christopher, Tolonen, Charlotte, Gauthier, Laura D., Gupta, Namrata, MacArthur, Daniel G., Rehm, Heidi L., Seed, Cotton, Philippakis, Anthony A., Daly, Mark J., Davis, J. Wade, Runz, Heiko, Miller, Melissa R., Neale, Benjamin M.

Get full text

Different mutational rates and mechanisms in human cells at pregastrulation and neurogenesis by Bae, Taejeong, Tomasini, Livia, Mariani, Jessica, Zhou, Bo, Roychowdhury, Tanmoy, Franjic, Daniel, Pletikos, Mihovil, Pattni, Reenal, Chen, Bo-Juen, Venturini, Elisa, Riley-Gillis, Bridget, Sestan, Nenad, Urban, Alexander E, Abyzov, Alexej, Vaccarino, Flora M

Get full text

Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells by Bao, Erik L., Nandakumar, Satish K., Liao, Xiaotian, Bick, Alexander G., Karjalainen, Juha, Tabaka, Marcin, Gan, Olga I., Havulinna, Aki S., Kiiskinen, Tuomo T. J., Lareau, Caleb A., de Lapuente Portilla, Aitzkoa L., Li, Bo, Emdin, Connor, Codd, Veryan, Nelson, Christopher P., Walker, Christopher J., Churchhouse, Claire, de la Chapelle, Albert, Klein, Daryl E., Nilsson, Björn, Wilson, Peter W. F., Cho, Kelly, Pyarajan, Saiju, Gaziano, J. Michael, Samani, Nilesh J., Regev, Aviv, Palotie, Aarno, Neale, Benjamin M., Dick, John E., Natarajan, Pradeep, O’Donnell, Christopher J., Daly, Mark J., Milyavsky, Michael, Kathiresan, Sekar, Sankaran, Vijay G.

Get full text

Genetic architecture of human plasma lipidome and its link to cardiovascular disease by Tabassum, Rubina, Rämö, Joel T., Ripatti, Pietari, Koskela, Jukka T., Kurki, Mitja, Karjalainen, Juha, Palta, Priit, Hassan, Shabbeer, Nunez-Fontarnau, Javier, Kiiskinen, Tuomo T. J., Söderlund, Sanni, Matikainen, Niina, Gerl, Mathias J., Surma, Michal A., Klose, Christian, Stitziel, Nathan O., Laivuori, Hannele, Havulinna, Aki S., Service, Susan K., Salomaa, Veikko, Pirinen, Matti, Jauhiainen, Matti, Daly, Mark J., Freimer, Nelson B., Palotie, Aarno, Taskinen, Marja-Riitta, Simons, Kai, Ripatti, Samuli

Get full text

Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy by Ollila, Hanna M., Sharon, Eilon, Lin, Ling, Sinnott-Armstrong, Nasa, Ambati, Aditya, Yogeshwar, Selina M., Hillary, Ryan P., Jolanki, Otto, Faraco, Juliette, Einen, Mali, Luo, Guo, Zhang, Jing, Han, Fang, Yan, Han, Dong, Xiao Song, Li, Jing, Zhang, Jun, Hong, Seung-Chul, Kim, Tae Won, Dauvilliers, Yves, Barateau, Lucie, Lammers, Gert Jan, Fronczek, Rolf, Mayer, Geert, Santamaria, Joan, Arnulf, Isabelle, Knudsen-Heier, Stine, Bredahl, May Kristin Lyamouri, Thorsby, Per Medbøe, Plazzi, Giuseppe, Pizza, Fabio, Moresco, Monica, Crowe, Catherine, Van den Eeden, Stephen K., Lecendreux, Michel, Bourgin, Patrice, Kanbayashi, Takashi, Martínez-Orozco, Francisco J., Peraita-Adrados, Rosa, Benetó, Antonio, Montplaisir, Jacques, Desautels, Alex, Huang, Yu-Shu, Jennum, Poul, Nevsimalova, Sona, Kemlink, David, Iranzo, Alex, Overeem, Sebastiaan, Wierzbicka, Aleksandra, Geisler, Peter, Sonka, Karel, Honda, Makoto, Högl, Birgit, Stefani, Ambra, Coelho, Fernando Morgadinho, Mantovani, Vilma, Feketeova, Eva, Wadelius, Mia, Eriksson, Niclas, Smedje, Hans, Hallberg, Pär, Hesla, Per Egil, Rye, David, Pelin, Zerrin, Ferini-Strambi, Luigi, Bassetti, Claudio L., Mathis, Johannes, Khatami, Ramin, Aran, Adi, Nampoothiri, Sheela, Olsson, Tomas, Kockum, Ingrid, Partinen, Markku, Perola, Markus, Kornum, Birgitte R., Rueger, Sina, Winkelmann, Juliane, Miyagawa, Taku, Toyoda, Hiromi, Khor, Seik-Soon, Shimada, Mihoko, Tokunaga, Katsushi, Rivas, Manuel, Pritchard, Jonathan K., Risch, Neil, Kutalik, Zoltan, O’Hara, Ruth, Hallmayer, Joachim, Ye, Chun Jimmie, Mignot, Emmanuel J.

Get full text

Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata by Sliz, Eeva, Tyrmi, Jaakko S., Rahmioglu, Nilufer, Zondervan, Krina T., Becker, Christian M., Uimari, Outi, Kettunen, Johannes

Get full text

Integrative genetic analysis of mouse and human AML identifies cooperating disease alleles by Hatlen, Megan A, Arora, Kanika, Vacic, Vladimir, Grabowska, Ewa A, Liao, Willey, Riley-Gillis, Bridget, Oschwald, Dayna M, Wang, Lan, Joergens, Jacob E, Shih, Alan H, Rapaport, Franck, Gu, Shengqing, Voza, Francesca, Asai, Takashi, Neel, Benjamin G, Kharas, Michael G, Gonen, Mithat, Levine, Ross L, Nimer, Stephen D

Get full text

The public health impact of poor sleep on severe COVID-19, influenza and upper respiratory infections by Maisha, Fahrisa I., Strausz, Satu J., Lammi, Vilma, Plenge, Robert, Ehm, Margaret G., Auro, Kirsi, Longerich, Simonne, Chatelain, Clement, O´Donnell, Chris, Kaprio, Jaakko, Virolainen, Petri, Raivio, Taneli, Tikkanen, Jani, Kosma, Veli-Matti, Laukkanen, Jari, Ding, Zhihao, Hu, Xinli, Hedman, Åsa, Renaud, Nicole, Ripatti, Samuli, Arvas, Mikko, Hinttala, Reetta, Kettunen, Johannes, Mäkelä, Johanna, Hiltunen, Mikko, Peltola, Jukka, Raivio, Minna, Partanen, Juulia, Abbasi, Ali, Eaton, Susan, Xu, Fanli, Addis, Laura, Eicher, John, Pikkarainen, Sampsa, Jussila, Airi, Voutilainen, Markku, Miller, Jason, Miller, Melissa, Eklund, Kari, Lertratanakul, Apinya, Pelkonen, Margit, Mouded, Majd, Ngo, Debby, Niiranen, Teemu, Aittokallio, Jenni, Hernesniemi, Jussi, Hiltunen, Timo, Reeve, Mary Pat, Mattson, Johanna, Auranen, Annika, Auvinen, Päivi, Fabre, Margarete, Kulkarni, Diptee, Loboda, Andrey, Ollila, Terhi, Loomis, Stephanie, Hannula-Jouppi, Katariina, Salmi, Teea, Pussinen, Pirkko, Salo, Tuula, Siponen, Maria, Mäntylä, Päivi, Anttonen, Vuokko, Kotaniemi-Talonen, Laura, Välimäki, Niko, Laakkonen, Eija, Laisk, Triin, Isometsä, Erkki, Ollila, Hanna, Mäkitie, Antti, Aarnisalo, Antti, Aittomäki, Kristiina, Havulinna, Aki, Della Briotta Parolo, Pietro, Liu, Aoxing, Ganna, Andrea, Heyne, Henrike, Rodosthenous, Rodos, Palotie, Tuula, Palin, Kimmo, Garcia-Tabuenca, Javier, Siirtola, Harri, Kristiansson, Kati, Ritari, Jarmo, Pylkäs, Katri, Karjalainen, Minna, Mantere, Tuomo, Siltanen, Sanna, Kuopio, Teijo, Kajanne, Risto, Aavikko, Mervi, Zheng, Zhili, Kaunisto, Mari, Kytölä, Anastasia, Weldatsadik, Rigbe, Laiho, Päivi, Wong, Regis, Koskelainen, Sami, Lehto, Petri, Redline, Susan

Get full text

FinnGen provides genetic insights from a well-phenotyped isolated population by Kurki, Mitja I., Karjalainen, Juha, Palta, Priit, Sipilä, Timo P., Donner, Kati M., Reeve, Mary P., Laivuori, Hannele, Kaunisto, Mari A., Loukola, Anu, Lahtela, Elisa, Mattsson, Hannele, Laiho, Päivi, Della Briotta Parolo, Pietro, Lehisto, Arto A., Kanai, Masahiro, Mars, Nina, Heyne, Henrike O., Veerapen, Kumar, Rüeger, Sina, Lemmelä, Susanna, Zhou, Wei, Ruotsalainen, Sanni, Pärn, Kalle, Hiekkalinna, Tero, Koskelainen, Sami, Llorens, Vincent, Gracia-Tabuenca, Javier, Siirtola, Harri, Reis, Kadri, Elnahas, Abdelrahman G., Aalto-Setälä, Katriina, Biswas, Shameek, Dada, Oluwaseun A., Ding, Zhihao, Ehm, Margaret G., Eklund, Kari, Färkkilä, Martti, Finucane, Hilary, Ganna, Andrea, Ghazal, Awaisa, Hakanen, Antti, Hu, Xinli, Hunkapiller, Julie, Jacob, Howard, Jensen, Jan-Nygaard, Joensuu, Heikki, John, Sally, Junttila, Juhani, Kähönen, Mika, Kallio, Lila, Kaprio, Jaakko, Kettunen, Johannes, Kilpeläinen, Elina, Kosma, Veli-Matti, Kuopio, Teijo, Laisk, Triin, Laukkanen, Jari, Liu, Aoxing, Mägi, Reedik, Mäkitie, Antti, Malarstig, Anders, Maranville, Joseph, Niemi, Mari E. K., Niemi, Marianna, Obeidat, Ma´en, Okafo, George, Palomäki, Antti, Palotie, Tuula, Pitkäranta, Anne, Pulford, David, Raghavan, Neha, Rahimov, Fedik, Riley-Gillis, Bridget, Rodosthenous, Rodosthenis, Salminen, Eveliina, Salomaa, Veikko, Schleutker, Johanna, Serpi, Raisa, Shen, Huei-yi, Siegel, Richard, Sul, Jae Hoon, Tachmazidou, Ioanna, Tienari, Pentti, Tukiainen, Taru, Vaura, Felix, Virolainen, Petri, Waring, Jeffrey, Waterworth, Dawn, Yang, Robert, Nelis, Mari, Metspalu, Andres, Milani, Lili, Fox, Caroline, Havulinna, Aki S., Perola, Markus, Jalanko, Anu, Plenge, Robert, Runz, Heiko, Daly, Mark J., Palotie, Aarno

Get full text

Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease by Vasanthakumar, Aparna, Davis, Justin W, Idler, Kenneth, Waring, Jeffrey F, Asque, Elizabeth, Riley-Gillis, Bridget, Grosskurth, Shaun, Srivastava, Gyan, Kim, Sungeun, Nho, Kwangsik, Nudelman, Kelly N H, Faber, Kelley, Sun, Yu, Foroud, Tatiana M, Estrada, Karol, Apostolova, Liana G, Li, Qingqin S, Saykin, Andrew J

Get full text

Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population by Kurki, Mitja I., Karjalainen, Juha, Palta, Priit, Sipilä, Timo P., Donner, Kati M., Reeve, Mary P., Laivuori, Hannele, Kaunisto, Mari A., Loukola, Anu, Lahtela, Elisa, Mattsson, Hannele, Laiho, Päivi, Della Briotta Parolo, Pietro, Lehisto, Arto A., Kanai, Masahiro, Mars, Nina, Heyne, Henrike O., Veerapen, Kumar, Rüeger, Sina, Lemmelä, Susanna, Zhou, Wei, Ruotsalainen, Sanni, Pärn, Kalle, Hiekkalinna, Tero, Koskelainen, Sami, Llorens, Vincent, Gracia-Tabuenca, Javier, Siirtola, Harri, Reis, Kadri, Elnahas, Abdelrahman G., Aalto-Setälä, Katriina, Biswas, Shameek, Dada, Oluwaseun A., Ding, Zhihao, Ehm, Margaret G., Eklund, Kari, Färkkilä, Martti, Finucane, Hilary, Ganna, Andrea, Ghazal, Awaisa, Hakanen, Antti, Hu, Xinli, Hunkapiller, Julie, Jacob, Howard, Jensen, Jan-Nygaard, Joensuu, Heikki, John, Sally, Junttila, Juhani, Kähönen, Mika, Kallio, Lila, Kaprio, Jaakko, Kettunen, Johannes, Kilpeläinen, Elina, Kosma, Veli-Matti, Kuopio, Teijo, Laisk, Triin, Laukkanen, Jari, Liu, Aoxing, Mägi, Reedik, Mäkitie, Antti, Malarstig, Anders, Maranville, Joseph, Niemi, Mari E. K., Niemi, Marianna, Obeidat, Ma´en, Okafo, George, Palomäki, Antti, Palotie, Tuula, Pitkäranta, Anne, Pulford, David, Raghavan, Neha, Rahimov, Fedik, Riley-Gillis, Bridget, Rodosthenous, Rodosthenis, Salminen, Eveliina, Salomaa, Veikko, Schleutker, Johanna, Serpi, Raisa, Shen, Huei-yi, Siegel, Richard, Sul, Jae Hoon, Tachmazidou, Ioanna, Tienari, Pentti, Tukiainen, Taru, Vaura, Felix, Virolainen, Petri, Waring, Jeffrey, Waterworth, Dawn, Yang, Robert, Nelis, Mari, Metspalu, Andres, Milani, Lili, Fox, Caroline, Havulinna, Aki S., Perola, Markus, Jalanko, Anu, Plenge, Robert, Runz, Heiko, Daly, Mark J., Palotie, Aarno

Get full text

Different mutational rates and mechanisms in human cells at pre-gastrulation and neurogenesis by Bae, Taejeong, Tomasini, Livia, Mariani, Jessica, Zhou, Bo, Roychowdhury, Tanmoy, Franjic, Daniel, Pletikos, Mihovil, Pattni, Reenal, Chen, Bo-Juen, Venturini, Elisa, Riley-Gillis, Bridget, Sestan, Nenad, Urban, Alexander E, Abyzov, Alexej, Vaccarino, Flora M

Get full text

Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis by Ruotsalainen, Sanni E., Surakka, Ida, Mars, Nina, Karjalainen, Juha, Kurki, Mitja, Kanai, Masahiro, Krebs, Kristi, Graham, Sarah, Mishra, Pashupati P., Mishra, Binisha H., Sinisalo, Juha, Palta, Priit, Lehtimäki, Terho, Raitakari, Olli, Milani, Lili, Okada, Yukinori, Palotie, Aarno, Widen, Elisabeth, Daly, Mark J., Ripatti, Samuli

Get full text

Integrative Analysis of the Mutational Landscape of Mouse and Human AML Identifies Functionally Relevant Leukemia Disease Alleles by Hatlen, Megan A., Arora, Kanika, Vacic, Vladimir, Grabowska, Ewa A., Liao, Willey, Riley-Gillis, Bridget, Oschwald, Dayna M., Wang, Lan, Joergens, Jacob E., Shih, Alan H., Rapaport, Franck, Gu, Shengqing, Voza, Francesca, Asai, Takashi, Neel, Benjamin, Kharas, Michael G., Gonen, Mithat, Levine, Ross L., Nimer, Stephen D.

Get full text