Search Results - Rivest, Brianna

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  1. 1
    Self-delivering RNAi immunotherapeutic PH-762 silences PD-1 to generate local and abscopal antitumor efficacy

    Self-delivering RNAi immunotherapeutic PH-762 silences PD-1 to generate local and abscopal antitumor efficacy by Cuiffo, Benjamin, Maxwell, Melissa, Yan, Dingxue, Guemiri, Ramdane, Boone, Andrew, Bellet, Deborah, Rivest, Brianna, Cardia, James, Robert, Caroline, Fricker, Simon P

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  2. 2
    474 Intratumoral CTLA-4-targeting INTASYL™ self-delivering RNAi enhances tumor control in combination with systemic anti-PD-1 antibody therapy in vivo suggesting a strategy to mitigate irSAEs

    474 Intratumoral CTLA-4-targeting INTASYL™ self-delivering RNAi enhances tumor control in combination with systemic anti-PD-1 antibody therapy in vivo suggesting a strategy to miti... by Cuiffo, Benjamin, Yan, Dingxue, Boone, Andrew, Rivest, Brianna, Maxwell, Melissa, Cardia, James

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  3. 3
    869 Locally administered immunotherapy self-delivering RNAi PH-762 results in abscopal clearance of untreated distal tumors, suggesting systemic immune response, in a murine hepatocarcinoma model

    869 Locally administered immunotherapy self-delivering RNAi PH-762 results in abscopal clearance of untreated distal tumors, suggesting systemic immune response, in a murine hepato... by Cuiffo, Benjamin, Maxwell, Melissa, Yan, Dingxue, Rivest, Brianna, Cardia, James, Fricker, Simon

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  4. 4
    INTASYL self-delivering RNAi decreases TIGIT expression, enhancing NK cell cytotoxicity: a potential application to increase the efficacy of NK adoptive cell therapy against cancer

    INTASYL self-delivering RNAi decreases TIGIT expression, enhancing NK cell cytotoxicity: a potential application to increase the efficacy of NK adoptive cell therapy against cancer by Maxwell, Melissa, Yan, Dingxue, Rivest, Brianna, Boone, Andrew, Cardia, James, Noessner, Elfriede

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  5. 5
    Abstract P109: Targeting BRD4 in T cells with self-delivering RNAi PH-894 for immunotherapy

    Abstract P109: Targeting BRD4 in T cells with self-delivering RNAi PH-894 for immunotherapy by Maxwell, Melissa, Ujiie, Daisuke, Cuiffo, Benjamin, Rivest, Brianna, Yan, Dingxue, Cardia, James, Melief, Jeroen, Kiessling, Rolf, Fricker, Simon P.

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  6. 6
    Abstract C109: INTASYL™ PH-894 self-delivering RNAi targeting BRD4 enhances the antigenicity of melanoma cells through MART-1 upregulation

    Abstract C109: INTASYL™ PH-894 self-delivering RNAi targeting BRD4 enhances the antigenicity of melanoma cells through MART-1 upregulation by Rivest, Brianna, Maxwell, Melissa, Boone, Andrew, Cuiffo, Benjamin, Yan, Dingxue, Cardia, James

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  7. 7
    Abstract C107: INTASYL™ self-delivering RNAi therapeutic targeting BRD4 elicits on-target apoptosis of human tumor cells

    Abstract C107: INTASYL™ self-delivering RNAi therapeutic targeting BRD4 elicits on-target apoptosis of human tumor cells by Boone, Andrew, Yan, Dingxue, Maxwell, Melissa, Rivest, Brianna, Cardia, James, Cuiffo, Benjamin

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  8. 8
    Abstract 1846: Intratumoral mPH-762, a self-delivering RNAi therapeutic (INTASYL™) targeting mouse PD-1, generates systemic tumor-specific memory CD8 T cells, providing a mechanism for abscopal efficacy toward untreated tumors in a murine hepatocarcinoma model

    Abstract 1846: Intratumoral mPH-762, a self-delivering RNAi therapeutic (INTASYL™) targeting mouse PD-1, generates systemic tumor-specific memory CD8 T cells, providing a mechanism... by Cuiffo, Benjamin G., Boone, Andrew, Yan, Dingxue, Maxwell, Melissa, Rivest, Brianna, Cardia, James, Fricker, Simon P.

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  9. 9
    Abstract 5113: INTASYL self-delivering RNAi therapeutic dual targeting PD-1 and CTLA-4 provides synergistic antitumor efficacy in the treatment of murine colon cancer in vivo

    Abstract 5113: INTASYL self-delivering RNAi therapeutic dual targeting PD-1 and CTLA-4 provides synergistic antitumor efficacy in the treatment of murine colon cancer in vivo by Cuiffo, Benjamin G., Boone, Andrew, Yan, Dingxue, Maxwell, Melissa, Rivest, Brianna, Cardia, James, Fricker, Simon P.

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  10. 10
    1402 PH 894: an INTASYL self-delivering siRNA targeting BRD4 has dual functions to sensitize tumor cell killing and activate CD8 T cells

    1402 PH 894: an INTASYL self-delivering siRNA targeting BRD4 has dual functions to sensitize tumor cell killing and activate CD8 T cells by Zhou, Shenghua, Cuiffo, Benjamin, Maxwell, Melissa, Dingxue Yan, Rivest, Brianna, Boone, Andrew, Cardia, James, Fricker, Simon

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  11. 11
    Abstract 4237: Local administration of BRD4-targeting self-delivering RNAi (PH-894) provides abscopal efficacy toward untreated distal tumors and potentiates the efficacy of systemic anti-PD-1 antibody therapy

    Abstract 4237: Local administration of BRD4-targeting self-delivering RNAi (PH-894) provides abscopal efficacy toward untreated distal tumors and potentiates the efficacy of system... by Cuiffo, Benjamin, Maxwell, Melissa, Yan, Dingxue, Zhou, Shenghua, Rivest, Brianna, Boone, Andrew, Cardia, James, Fricker, Simon P.

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