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Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis
by
SCHNUTE, Mark E
,
O'BRIEN, Patrick M
,
CARROLL, Jeffery N
,
PATT, William C
,
SHIEH, Huey S
,
COLLINS, Brandon
,
PAVLOVSKY, Alexander G
,
PALMQUIST, Katherine E
,
ASTON, Karl W
,
HITCHCOCK, Jeffrey
,
ROGERS, Michael D
,
MCDONALD, Joseph
,
NAHRA, Joe
,
JOHNSON, Adam R
,
MUNIE, Grace E
,
WITTWER, Arthur J
,
MAN, Chiu-Fai
,
SETTLE, Steven L
,
NEMIROVSKIY, Olga
,
VICKERY, Lillian E
,
AGAWAL, Arun
,
DYER, Richard D
,
SUNYER, Teresa
,
MORRIS, Mark
,
HOWARD ROARK, W
,
HANAU, Cathleen E
,
RUMINSKI, Peter G
,
SCHOLTEN, Jeffrey A
,
FLETCHER, Theresa R
,
HAMPER, Bruce C
Published in
Bioorganic & medicinal chemistry letters
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Discovery of (pyridin-4-yl)-2 H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis
by
Schnute, Mark E.
,
O’Brien, Patrick M.
,
Nahra, Joe
,
Morris, Mark
,
Howard Roark, W.
,
Hanau, Cathleen E.
,
Ruminski, Peter G.
,
Scholten, Jeffrey A.
,
Fletcher, Theresa R.
,
Hamper, Bruce C.
,
Carroll, Jeffery N.
,
Patt, William C.
,
Shieh, Huey S.
,
Collins, Brandon
,
Pavlovsky, Alexander G.
,
Palmquist, Katherine E.
,
Aston, Karl W.
,
Hitchcock, Jeffrey
,
Rogers, Michael D.
,
McDonald, Joseph
,
Johnson, Adam R.
,
Munie, Grace E.
,
Wittwer, Arthur J.
,
Man, Chiu-Fai
,
Settle, Steven L.
,
Nemirovskiy, Olga
,
Vickery, Lillian E.
,
Agawal, Arun
,
Dyer, Richard D.
,
Sunyer, Teresa
Published in
Bioorganic & medicinal chemistry letters
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Journal Title
Bioorganic & Medicinal Chemistry Letters
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Subjects
Dmoad
2 results
2
Mmp
2 results
2
Osteoarthritis
2 results
2
Administration, Oral
1 results
1
Animals
1 results
1
Binding Sites
1 results
1
Biological And Medical Sciences
1 results
1
Bones, Joints And Connective Tissue. Antiinflammatory Agents
1 results
1
Cartilage - Drug Effects
1 results
1
Cartilage - Metabolism
1 results
1
Catalytic Domain
1 results
1
Chemistry
1 results
1
Chemistry, Medicinal
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1
Chemistry, Organic
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1
Crystallography, X-Ray
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Disease Models, Animal
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Drug Discovery
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Life Sciences & Biomedicine
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1
Matrix Metalloproteinase 13 - Metabolism
1 results
1
Matrix Metalloproteinase Inhibitors
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Sciencedirect (Online Service)
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Sciencedirect Journals
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Backfile Package - Organic Chemistry (Legacy) [Yco]
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