The role of the Th17 cytokines IL-17 and IL-22 in Rheumatoid Arthritis pathogenesis and developments in cytokine immunotherapy by Roeleveld, Debbie M., Koenders, Marije I.

Get full text

Higher efficacy of anti-IL-6/IL-21 combination therapy compared to monotherapy in the induction phase of Th17-driven experimental arthritis by Roeleveld, Debbie M, Marijnissen, Renoud J, Walgreen, Birgitte, Helsen, Monique M, van den Bersselaar, Liduine, van de Loo, Fons A, van Lent, Peter L, van der Kraan, Peter M, van den Berg, Wim B, Koenders, Marije I

Get full text

Interleukin‐21 Receptor Deficiency Increases the Initial Toll‐like Receptor 2 Response but Protects Against Joint Pathology by Reducing Th1 and Th17 Cells During Streptococcal Cell... by Marijnissen, Renoud J., Roeleveld, Debbie M., Young, Deborah, Nickerson‐Nutter, Cheryl, Abdollahi‐Roodsaz, Shahla, Garcia de Aquino, Sabrina, de Loo, Fons A. J., Spriel, Annemiek B., Boots, Annemieke M. H., den Berg, Wim B., Koenders, Marije I.

Get full text

Systemic overexpression of interleukin-22 induces the negative immune-regulator SOCS3 and potently reduces experimental arthritis in mice by Aarts, Joyce, Roeleveld, Debbie M, Helsen, Monique M, Walgreen, Birgitte, Vitters, Elly L, Kolls, Jay, van de Loo, Fons A, van Lent, Peter L, van der Kraan, Peter M, Koenders, Marije I

Get full text

Imaging fibroblast activation protein to monitor therapeutic effects of neutralizing interleukin-22 in collagen-induced arthritis by van der Geest, Tessa, Roeleveld, Debbie M, Walgreen, Birgitte, Helsen, Monique M, Nayak, Tapan K, Klein, Christian, Hegen, Martin, Storm, Gert, Metselaar, Josbert M, van den Berg, Wim B, van der Kraan, Peter M, Laverman, Peter, Boerman, Otto C, Koenders, Marije I

Get full text

The Th17 Pathway as a Therapeutic Target in Rheumatoid Arthritis and Other Autoimmune and Inflammatory Disorders by Roeleveld, Debbie M., van Nieuwenhuijze, Annemarie E. M., van den Berg, Wim B., Koenders, Marije I.

Get full text

Microbiota‐Dependent Involvement of Th17 Cells in Murine Models of Inflammatory Arthritis by Evans‐Marin, Heather, Rogier, Rebecca, Koralov, Sergei B., Manasson, Julia, Roeleveld, Debbie, Kraan, Peter M., Scher, Jose U., Koenders, Marije I., Abdollahi‐Roodsaz, Shahla

Get full text

Pregnancy and Birth Cohort Resources in Europe: a Large Opportunity for Aetiological Child Health Research by Larsen, Pernille Stemann, Kamper-Jørgensen, Mads, Adamson, Ashley, Barros, Henrique, Bonde, Jens Peter, Brescianini, Sonia, Brophy, Sinead, Casas, Maribel, Devereux, Graham, Eggesbø, Merete, Fantini, Maria Pia, Frey, Urs, Gehring, Ulrike, Grazuleviciene, Regina, Henriksen, Tine Brink, Hertz-Picciotto, Irva, Heude, Barbara, Hryhorczuk, Daniel O., Inskip, Hazel, Jaddoe, Vincent W.V., Lawlor, Debbie A, Ludvigsson, Johnny, Kelleher, Cecily, Kiess, Wieland, Koletzko, Berthold, Kuehni, Claudia Elisabeth, Kull, Inger, Kyhl, Henriette Boye, Magnus, Per, Momas, Isabelle, Murray, Dierdre, Pekkanen, Juha, Polanska, Kinga, Porta, Daniela, Poulsen, Gry, Richiardi, Lorenzo, Roeleveld, Nel, Skovgaard, Anne Mette, Sram, Radim J., Strandberg-Larsen, Katrine, Thijs, Carel, Van Eijsden, Manon, Wright, John, Vrijheid, Martine, Andersen, Anne-Marie Nybo

Get full text

Changes in parental smoking during pregnancy and risks of adverse birth outcomes and childhood overweight in Europe and North America: An individual participant data meta-analysis... by Philips, Elise M, Santos, Susana, Trasande, Leonardo, Aurrekoetxea, Juan J, Barros, Henrique, von Berg, Andrea, Bergström, Anna, Bird, Philippa K, Brescianini, Sonia, Ní Chaoimh, Carol, Charles, Marie-Aline, Chatzi, Leda, Chevrier, Cécile, Chrousos, George P, Costet, Nathalie, Criswell, Rachel, Crozier, Sarah, Eggesbø, Merete, Fantini, Maria Pia, Farchi, Sara, Forastiere, Francesco, van Gelder, Marleen M H J, Georgiu, Vagelis, Godfrey, Keith M, Gori, Davide, Hanke, Wojciech, Heude, Barbara, Hryhorczuk, Daniel, Iñiguez, Carmen, Inskip, Hazel, Karvonen, Anne M, Kenny, Louise C, Kull, Inger, Lawlor, Debbie A, Lehmann, Irina, Magnus, Per, Manios, Yannis, Melén, Erik, Mommers, Monique, Morgen, Camilla S, Moschonis, George, Murray, Deirdre, Nohr, Ellen A, Nybo Andersen, Anne-Marie, Oken, Emily, Oostvogels, Adriëtte J J M, Papadopoulou, Eleni, Pekkanen, Juha, Pizzi, Costanza, Polanska, Kinga, Porta, Daniela, Richiardi, Lorenzo, Rifas-Shiman, Sheryl L, Roeleveld, Nel, Rusconi, Franca, Santos, Ana C, Sørensen, Thorkild I A, Standl, Marie, Stoltenberg, Camilla, Sunyer, Jordi, Thiering, Elisabeth, Thijs, Carel, Torrent, Maties, Vrijkotte, Tanja G M, Wright, John, Zvinchuk, Oleksandr, Gaillard, Romy, Jaddoe, Vincent W V

Get full text

IQCB1 mutations in patients with leber congenital amaurosis by Estrada-Cuzcano, Alejandro, Koenekoop, Robert K, Coppieters, Frauke, Kohl, Susanne, Lopez, Irma, Collin, Rob W J, De Baere, Elfride B W, Roeleveld, Debbie, Marek, Jonah, Bernd, Antje, Rohrschneider, Klaus, van den Born, L Ingeborgh, Meire, Françoise, Maumenee, Irene H, Jacobson, Samuel G, Hoyng, Carel B, Zrenner, Eberhart, Cremers, Frans P M, den Hollander, Anneke I

Get full text

Cathepsin B Mediated Lysosomal Degradation in Macrophages Controls the Pharmacokinetics of the Therapeutic Protein Asparaginase by Van Der Meer, Laurens T, Terry, Samantha YA, van Ingen Schenau, Dorette, Andree, Kiki, Franssen, Gerben M, Roeleveld, Debbie, Metselaar, Bart, Reinheckel, Thomas, Hoogerbrugge, Peter M, Boerman, Otto C, van Leeuwen, Frank N

Get full text

A germ line mutation in cathepsin B points toward a role in asparaginase pharmacokinetics by van der Meer, Laurens T., Waanders, Esmé, Levers, Marloes, Venselaar, Hanka, Roeleveld, Debbie, Boos, Joachim, Lanvers, Claudia, Brüggemann, Roger J., Kuiper, Roland P., Hoogerbrugge, Peter M., van Leeuwen, Frank N., te Loo, D. Maroeska

Get full text

A Germline Mutation in Cathepsin B in a Child with ALL Points towards a Key Role for This Enzyme in L-Asparaginase Pharmacokinetics by van der Meer, Laurens T., Waanders, Esmé, Levers, Marloes, Venselaar, Hanka, Roeleveld, Debbie, Boos, Joachim, Lanvers-Kaminsky, Claudia, Kuiper, Roland P., Hoogerbrugge, Peter M., van Leeuwen, Frank N., te Loo, D. Maroeska W.M.

Get full text