Search Results - Rominger, Dave

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  1. 1
    Abstract P237: PRT2527 is a potent and selective CDK9 inhibitor that demonstrates anti-cancer activity in preclinical models of hematological malignancies and solid tumors with MYC amplification

    Abstract P237: PRT2527 is a potent and selective CDK9 inhibitor that demonstrates anti-cancer activity in preclinical models of hematological malignancies and solid tumors with MYC... by Zhang, Yang W., Lu, Liang, Wang, Min, Rominger, Dave, Ruepp, Stefan, Gallagher, Kirsten, Gowen-MacDonald, William, Dai, Chaofeng, Cowart, Miles, Combs, Andrew, Ruggeri, Bruce, Scherle, Peggy, Vaddi, Kris

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  2. 2
    Abstract 2919: Discovery of PRT811, a potent, selective, and orally bioavailable brain penetrant PRMT5 Inhibitor for the treatment of brain tumors

    Abstract 2919: Discovery of PRT811, a potent, selective, and orally bioavailable brain penetrant PRMT5 Inhibitor for the treatment of brain tumors by Zhang, Yang, Lin, Hong, Wang, Min, Angelis, Dimitrios, Hawkins, Michael, Rominger, Dave, Emm, Tom, Luengo, Juan, Ruggeri, Bruce, Scherle, Peggy, Vaddi, Kris

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  3. 3
    Abstract 2915: Preclinical characterization of PRT543, a potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5), with broad antitumor activity in in vitro and in vivo models

    Abstract 2915: Preclinical characterization of PRT543, a potent and selective inhibitor of protein arginine methyltransferase 5 (PRMT5), with broad antitumor activity in in vitro a... by Bhagwat, Neha, Zhang, Yang, Lin, Hong, Wang, Min, Rominger, Dave, Emm, Tom, Chugani-Mahtani, Divya, Angelis, Dimitrios, Shetty, Rupa, Leal, Raul, Gowen-MacDonald, William, Grego, Alexander, Luengo, Juan, Manshouri, Taghi, Pastore, Friederike, Levine, Ross L., Verstovsek, Srdan, Ruggeri, Bruce, Scherle, Peggy, Vaddi, Kris

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  4. 4
    Abstract LB320: Discovery and characterization of QTX3034, a potent, selective, and orally bioavailable allosteric KRAS inhibitor

    Abstract LB320: Discovery and characterization of QTX3034, a potent, selective, and orally bioavailable allosteric KRAS inhibitor by Zhang, Yang W., Rominger, Dave, Vo, Elizabeth Donohue, Silva, Jillian M., Zhang, Yang J., Lee, Greg, Micozzi, John, Reid, Ben, McDonough, Brooke, Hospital, Audrey, Luengo, Juan I., Pitt, Cameron, Lin, Hong

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  5. 5
    Abstract LB321: Discovery and characterization of QTX3046, a potent, selective, and orally bioavailable non-covalent KRASG12D inhibitor

    Abstract LB321: Discovery and characterization of QTX3046, a potent, selective, and orally bioavailable non-covalent KRASG12D inhibitor by Vo, Elizabeth Donohue, Zhang, Yang W., Rominger, Dave, Silva, Jillian M., Zhang, Yang J., Lee, Greg, Micozzi, John, Reid, Ben, McDonough, Brooke, Hospital, Audrey, Luengo, Juan I., Lin, Hong, Pitt, Cameron

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  6. 6
    Abstract 2300: Brain penetrant CDK4/6 inhibitor PRT3645 demonstrates anti-tumor activity and enhances survival in glioblastoma and breast cancer brain metastasis models

    Abstract 2300: Brain penetrant CDK4/6 inhibitor PRT3645 demonstrates anti-tumor activity and enhances survival in glioblastoma and breast cancer brain metastasis models by Juvekar, Ashish, Zhang, Yang, Buesking, Andrew, Wang, Min, Rominger, Dave, Rager, Joseph, Ruepp, Stefan, Gallagher, Kirsten, Zou, Yue, Cowart, Miles, Wu, Xiaowei, Pawley, Sarah, Holmes, Ryan, Gowen-MacDonald, William, Vaddi, Kris, Combs, Andrew, Ruggeri, Bruce, Scherle, Peggy

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