Safety, Pharmacokinetics, and Pharmacodynamics of a First-in-Class ClC-1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial by Ruijs, Titia Q, de Cuba, Catherine M K E, Heuberger, Jules A A C, Hutchison, John, Bold, Jane, Grønnebæk, Thomas S, Jensen, Klaus G, Chin, Eva, Quiroz, Jorge A, Petersen, Thomas K, Flagstad, Peter, de Kam, Marieke L, van Esdonk, Michiel J, Klaassen, Erica, Doll, Robert J, Koopmans, Ingrid W, de Goede, Annika A, Aulin, Linda B S, Pedersen, Thomas H, Groeneveld, Geert Jan

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Effects of Mexiletine and Lacosamide on Nerve Excitability in Healthy Subjects: A Randomized, Double‐Blind, Placebo‐Controlled, Crossover Study by Ruijs, Titia Q., Koopmans, Ingrid W., Kam, Marieke L., Esdonk, Michiel J., Koltzenburg, Martin, Groeneveld, Geert Jan, Heuberger, Jules A.A.C.

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Muscle velocity recovery cycles as pharmacodynamic biomarker: Effects of mexiletine in a randomized double‐blind placebo‐controlled cross‐over study by Ruijs, Titia Q., Koopmans, Ingrid W., Kam, Marieke L., Tannemaat, Martijn R., Groeneveld, Geert Jan, Heuberger, Jules A. A. C.

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Transcranial magnetic stimulation as biomarker of excitability in drug development: A randomized, double‐blind, placebo‐controlled, cross‐over study by Ruijs, Titia Q., Heuberger, Jules A. A. C., Goede, Annika A., Ziagkos, Dimitrios, Otto, Marije E., Doll, Robert J., Putten, Michel J. A. M., Groeneveld, Geert Jan

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The ClC-1 chloride channel inhibitor NMD670 improves skeletal muscle function in rat models and patients with myasthenia gravis by Skov, Martin, Ruijs, Titia Q, Grønnebæk, Thomas S, Skals, Marianne, Riisager, Anders, Winther, Jeppe Blichfeldt, Dybdahl, Kamilla Løhde Tordrup, Findsen, Anders, Morgen, Jeanette J, Huus, Nete, Broch-Lips, Martin, Nielsen, Ole B, de Cuba, Catherine M K E, Heuberger, Jules A A C, de Kam, Marieke L, Tannemaat, Martijn, Verschuuren, Jan J G M, Knutsen, Lars J S, Kelly, Nicholas M, Jensen, Klaus G, Arnold, William D, Burghes, Arthur H, Olesen, Claus, Bold, Jane, Petersen, Thomas K, Quiroz, Jorge A, Hutchison, John, Chin, Eva R, Groeneveld, Geert J, Pedersen, Thomas H

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Transcranial magnetic stimulation as a translational biomarker for AMPA receptor modulation by O’Donnell, Patricio, Dijkstra, Francis M., Damar, Ugur, Quanhong, Lei, de Goede, Annika A., Xu, Lin, Pascual-Leone, Andres, Buhl, Derek L., Zuiker, Rob, Ruijs, Titia Q., Heuberger, Jules A. A. C., MacMullin, Paul, Lubell, Martin, Asgharnejad, Mahnaz, Murthy, Venkatesha, Rotenberg, Alexander, Jacobs, Gabriel E., Rosen, Laura

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TH-186. Muscle velocity recovery cycles as pharmacodynamic biomarker: Effects of mexiletine in a randomized, double-blind, placebo-controlled, cross-over study in healthy subjects by Ruijs, Titia, Heuberger, Jules, Koopmans, Ingrid, de Cuba, Kaye, de Kam, Marieke, Jan Groeneveld, Geert

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WE-167. Muscle velocity recovery cycles to examine muscle membrane properties in myasthenia gravis patients by de Cuba, Catherine, Ruijs, Titia, Koopmans, Ingrid, de Kam, Marieke, Jan Groeneveld, Geert, Heuberger, Jules

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HP58 : Effects of sodium channel blockers on “nerve exciatability threshold tracking by Ruijs, Titia, Heuberger, Jules, Koopmans, Ingrid, Kam, Marieke de, Jan Groeneveld, Geert

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N°356 - Muscle velocity recovery cycles as pharmacodynamic biomarker in a first-in-human trial of a first-in-class chloride channel 1 inhibitor: A randomized, double-blind, placebo... by de Cuba, Catherine, Heuberger, Jules, Ruijs, Titia, Hutchison, John, Bold, Jan, Skjærlund Grønnebæk, Thomas, Gjervig Jensen, Klaus, Chin, Eva, Quiroz, Jorge, de Kam, Marieke, Koopmans, Ingrid, de Goede, Annika, Holm Pedersen, Thomas, Jan Groeneveld, Geert

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Chorioretinal thinning in chronic kidney disease links to inflammation and endothelial dysfunction by Balmforth, Craig, van Bragt, Job Jmh, Ruijs, Titia, Cameron, James R, Kimmitt, Robert, Moorhouse, Rebecca, Czopek, Alicja, Hu, May Khei, Gallacher, Peter J, Dear, James W, Borooah, Shyamanga, MacIntyre, Iain M, Pearson, Tom Mc, Willox, Laura, Talwar, Dinesh, Tafflet, Muriel, Roubeix, Christophe, Sennlaub, Florian, Chandran, Siddharthan, Dhillon, Baljean, Webb, David J, Dhaun, Neeraj

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