Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: Sequential metabolism of deltamethrin revealed by Stevenson, Bradley J., Bibby, Jaclyn, Pignatelli, Patricia, Muangnoicharoen, Sant, O’Neill, Paul M., Lian, Lu-Yun, Müller, Pie, Nikou, Dimitra, Steven, Andrew, Hemingway, Janet, Sutcliffe, Michael J., Paine, Mark J.I.

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Atomic Description of an Enzyme Reaction Dominated by Proton Tunneling by Masgrau, Laura, Roujeinikova, Anna, Johannissen, Linus O, Hothi, Parvinder, Basran, Jaswir, Ranaghan, Kara E, Mulholland, Adrian J, Sutcliffe, Michael J, Scrutton, Nigel S, Leys, David

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Deep Tunneling Dominates the Biologically Important Hydride Transfer Reaction from NADH to FMN in Morphinone Reductase by Pang, Jiayun, Hay, Sam, Scrutton, Nigel S, Sutcliffe, Michael J

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Large-Scale Domain Conformational Change Is Coupled to the Activation of the Co–C Bond in the B12-Dependent Enzyme Ornithine 4,5-Aminomutase: A Computational Study by Pang, Jiayun, Li, Xin, Morokuma, Keiji, Scrutton, Nigel S, Sutcliffe, Michael J

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Drug block of the hERG potassium channel: Insight from modeling by Stansfeld, Phillip J., Gedeck, Peter, Gosling, Martin, Cox, Brian, Mitcheson, John S., Sutcliffe, Michael J.

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Promoting motions in enzyme catalysis probed by pressure studies of kinetic isotope effects by Hay, Sam, Sutcliffe, Michael J, Scrutton, Nigel S

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TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies by MACFARLANE, Marion, KOHLHAAS, Susan L, SUTCLIFFE, Michael J, DYER, Martin J. S, COHEN, Gerald M

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Quantum Mechanics/Molecular Mechanics Studies on the Sulfoxidation of Dimethyl Sulfide by Compound I and Compound 0 of Cytochrome P450: Which Is the Better Oxidant? by Porro, Cristina S, Sutcliffe, Michael J, de Visser, Sam P

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To what extent is capital expenditure in UK higher education meeting the pedagogical needs of staff and students? by Jones, Steven, Sutcliffe, Michael J., Bragg, Joanna, Harris, Diane

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Barrier Compression Enhances an Enzymatic Hydrogen-Transfer Reaction by Hay, Sam, Pudney, Christopher R, McGrory, Tom A, Pang, Jiayun, Sutcliffe, Michael J, Scrutton, Nigel S

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Cysteine Substitution Mutagenesis and the Effects of Methanethiosulfonate Reagents at P2X2 and P2X4 Receptors Support a Core Common Mode of ATP Action at P2X Receptors by Roberts, Jonathan A., Digby, Helen R., Kara, Madina, Ajouz, Sam El, Sutcliffe, Michael J., Evans, Richard J.

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Drug Binding Interactions in the Inner Cavity of hERG Channels: Molecular Insights from Structure-Activity Relationships of Clofilium and Ibutilide Analogs by Perry, Matthew, Stansfeld, Phillip J, Leaney, Joanne, Wood, Claire, de Groot, Marcel J, Leishman, Derek, Sutcliffe, Michael J, Mitcheson, John S

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H-tunneling in the Multiple H-transfers of the Catalytic Cycle of Morphinone Reductase and in the Reductive Half-reaction of the Homologous Pentaerythritol Tetranitrate Reductase by Basran, Jaswir, Harris, Richard J., Sutcliffe, Michael J., Scrutton, Nigel S.

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Hydrogen tunnelling in enzyme-catalysed H-transfer reactions: flavoprotein and quinoprotein systems by Sutcliffe, Michael J, Masgrau, Laura, Roujeinikova, Anna, Johannissen, Linus O, Hothi, Parvinder, Basran, Jaswir, Ranaghan, Kara E, Mulholland, Adrian J, Leys, David, Scrutton, Nigel S

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The enzyme aromatic amine dehydrogenase induces a substrate conformation crucial for promoting vibration that significantly reduces the effective potential energy barrier to proton... by Johannissen, Linus O, Scrutton, Nigel S, Sutcliffe, Michael J

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Validation of Model of Cytochrome P450 2D6:  An in Silico Tool for Predicting Metabolism and Inhibition by Kemp, Carol A, Flanagan, Jack U, van Eldik, Annamaria J, Maréchal, Jean-Didier, Wolf, C. Roland, Roberts, Gordon C. K, Paine, Mark J. I, Sutcliffe, Michael J

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Residues Glutamate 216 and Aspartate 301 Are Key Determinants of Substrate Specificity and Product Regioselectivity in Cytochrome P450 2D6 by Paine, Mark J.I., McLaughlin, Lesley A., Flanagan, Jack U., Kemp, Carol A., Sutcliffe, Michael J., Roberts, Gordon C.K., Wolf, C. Roland

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Are Environmentally Coupled Enzymatic Hydrogen Tunneling Reactions Influenced by Changes in Solution Viscosity by Hay, Sam, Pudney, Christopher R, Sutcliffe, Michael J, Scrutton, Nigel S

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Direct Analysis of Donor−Acceptor Distance and Relationship to Isotope Effects and the Force Constant for Barrier Compression in Enzymatic H-Tunneling Reactions by Pudney, Christopher R, Johannissen, Linus O, Sutcliffe, Michael J, Hay, Sam, Scrutton, Nigel S

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Kinetic Studies of the Mechanism of Carbon−Hydrogen Bond Breakage by the Heterotetrameric Sarcosine Oxidase of Arthrobacter sp. 1-IN by Harris, Richard J, Meskys, Rolandas, Sutcliffe, Michael J, Scrutton, Nigel S

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