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Activation of the Orphan Nuclear Receptor Steroidogenic Factor 1 by Oxysterols
by
Lala, Deepak S.
,
Syka, Peter M.
,
Lazarchik, Steven B.
,
Mangelsdorf, David J.
,
Parker, Keith L.
,
Heyman, Richard A.
Published in
Proceedings of the National Academy of Sciences - PNAS
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Tetrahydroquinoline glucocorticoid receptor agonists: Discovery of a 3-hydroxyl for improving receptor selectivity
by
Roach, Steven L.
,
Higuchi, Robert I.
,
Hudson, Andrew R.
,
Adams, Mark E.
,
Syka, Peter M.
,
Mais, Dale E.
,
Miner, Jeffrey N.
,
Marschke, Keith B.
,
Zhi, Lin
Published in
Bioorganic & medicinal chemistry letters
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Discovery of orally available tetrahydroquinoline-based glucocorticoid receptor agonists
by
Hudson, Andrew R.
,
Higuchi, Robert I.
,
Roach, Steven L.
,
Adams, Mark E.
,
Vassar, Angela
,
Syka, Peter M.
,
Mais, Dale E.
,
Miner, Jeffrey N.
,
Marschke, Keith B.
,
Zhi, Lin
Published in
Bioorganic & medicinal chemistry letters
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Nonsteroidal 2,3-dihydroquinoline glucocorticoid receptor agonists with reduced PEPCK activation
by
Hudson, Andrew R.
,
Higuchi, Robert I.
,
Roach, Steven L.
,
Valdez, Lino J.
,
Adams, Mark E.
,
Vassar, Angie
,
Rungta, Deepa
,
Syka, Peter M.
,
Mais, Dale E.
,
Marschke, Keith B.
,
Zhi, Lin
Published in
Bioorganic & medicinal chemistry letters
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Tetrahydroquinolin-3-yl carbamate glucocorticoid receptor agonists with reduced PEPCK activation
by
Roach, Steven L.
,
Higuchi, Robert I.
,
Hudson, Andrew R.
,
Vassar, Angie
,
Grant, Virginia H.S.
,
Lamer, Ryan
,
Hooper, Charlene
,
Rungta, Deepa
,
Syka, Peter M.
,
Mais, Dale E.
,
Marschke, Keith B.
,
Zhi, Lin
Published in
Bioorganic & medicinal chemistry letters
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Identification and Characterization of a Versatile Retinoid Response Element (Retinoic Acid Receptor Response Element-Retinoid X Receptor Response Element) in the Mouse Tissue Tran...
by
Nagy, Laszlo
,
Saydak, Margaret
,
Shipley, Nancy
,
Lu, Shan
,
Basilion, James P.
,
Yan, Zhong Hua
,
Syka, Peter
,
Chandraratna, Roshantha A.S.
,
Stein, Joseph P.
,
Heyman, Richard A.
,
Davies, Peter J.A.
Published in
The Journal of biological chemistry
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Discovery of potent, orally bioavailable in vivo efficacious antagonists of the TLR7/8 pathway
by
Alper, Phil B.
,
Deane, Jonathan
,
Betschart, Claudia
,
Buffet, David
,
Collignon Zipfel, Géraldine
,
Gordon, Perry
,
Hampton, Janice
,
Hawtin, Stuart
,
Ibanez, Maureen
,
Jiang, Tao
,
Junt, Tobias
,
Knoepfel, Thomas
,
Liu, Bo
,
Maginnis, Jillian
,
McKeever, Una
,
Michellys, Pierre-Yves
,
Mutnick, Daniel
,
Nayak, Bishnu
,
Niwa, Satoru
,
Richmond, Wendy
,
Rush, James S.
,
Syka, Peter
,
Zhang, Yi
,
Zhu, Xuefeng
Published in
Bioorganic & medicinal chemistry letters
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Discovery of the TLR7/8 Antagonist MHV370 for Treatment of Systemic Autoimmune Diseases
by
Alper, Phil
,
Betschart, Claudia
,
André, Cédric
,
Boulay, Thomas
,
Cheng, Dai
,
Deane, Jonathan
,
Faller, Michael
,
Feifel, Roland
,
Glatthar, Ralf
,
Han, Dong
,
Hemmig, Rene
,
Jiang, Tao
,
Knoepfel, Thomas
,
Maginnis, Jillian
,
Mutnick, Daniel
,
Pei, Wei
,
Ruzzante, Giulia
,
Syka, Peter
,
Zhang, Guobao
,
Zhang, Yi
,
Zink, Florence
,
Zipfel, Géraldine
,
Hawtin, Stuart
,
Junt, Tobias
,
Michellys, Pierre-Yves
Published in
ACS medicinal chemistry letters
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Discovery of Non-Peptidyl Small-Molecule Human GCSF Receptor Agonists for the Potential Treatment of Neutropenia
by
Marschke, Keith
,
Rungta, Deepa
,
Slavin, Daniela A
,
Sanders, Jennifer
,
Roach, Steven L
,
Pickens, Jason C
,
Shen, Yixing
,
van Oeveren, Arjan
,
Hong, Mei Hua
,
Sun, Hong
,
Bissonnette, Reid P.
,
Syka, Peter M
,
Zhi, Lin
Published in
Blood
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NON-Peptidyl Small Molecule EPO Receptor Agonists Are Potent Pathway Selective Inducers of Erythropoiesis
by
Bissonnette, Reid P.
,
Rungta, Deepa
,
Hudson, Andrew R
,
Roach, Steven L
,
Hong, Mei Hua
,
Sun, Hong
,
Hu, Junlian
,
Ward, James N
,
Luo, Wen
,
Sanders, Jen E
,
Syka, Peter M
,
Slavin, Daniela A
,
Zhi, Lin
,
Marschke, Keith B
Published in
Blood
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Synergistic Activation of the Hydratase but Not the ApoA1 Gene by Gemfibrozil and Retinoids
by
MUKHERJEE, RANJAN
,
JOW, LILY
,
STRASSER, JOSEF
,
SYKA, PETER
,
ROSEN, JONATHAN
,
HEYMAN, RICHARD
Published in
Annals of the New York Academy of Sciences
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Not cricket either
by
SYKA, PETER
Published in
Nature (London)
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Microvillin: A 200-Kilodalton Protein in Microvilli of Rat Mammary Cells Detected by a Monoclonal Antibody
by
Allen, Ross
,
Dulbecco, Renato
,
Syka, Peter
,
Bowman, Marianne
Published in
Proceedings of the National Academy of Sciences - PNAS
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Exposing the molecular heterogeneity of glycosylated biotherapeutics
by
Schachner, Luis F.
,
Mullen, Christopher
,
Phung, Wilson
,
Hinkle, Joshua D.
,
Beardsley, Michelle Irwin
,
Bentley, Tracy
,
Day, Peter
,
Tsai, Christina
,
Sukumaran, Siddharth
,
Baginski, Tomasz
,
DiCara, Danielle
,
Agard, Nicholas J.
,
Masureel, Matthieu
,
Gober, Joshua
,
ElSohly, Adel M.
,
Melani, Rafael
,
Syka, John E. P.
,
Huguet, Romain
,
Marty, Michael T.
,
Sandoval, Wendy
Published in
Nature communications
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