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Porcupine Inhibition Disrupts Mitochondrial Function and Homeostasis in WNT Ligand-Addicted Pancreatic Cancer
by
Aguilera, Kristina Y
,
Le, Thuc
,
Riahi, Rana
,
Lay, Anna R
,
Hinz, Stefan
,
Saadat, Edris A
,
Vashisht, Ajay A
,
Wohlschlegel, James
,
Donahue, Timothy R
,
Radu, Caius G
,
Dawson, David W
Published in
Molecular cancer therapeutics
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Abstract C01: Porcupine inhibition redirects mitochondrial metabolism in Wnt-dependent pancreatic cancer
by
Aguilera, Kristina Y.
,
Riahi, Rana
,
Saadat, Edris A.
,
Lay, Anna R.
,
Le, Thuc
,
Donahue, Timothy R.
,
Radu, Caius
,
Dawson, David W.
Published in
Cancer research (Chicago, Ill.)
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Abstract 1832: Ligand-dependent Wnt signaling directs metabolic adaptations to promote pancreatic tumorigenesis
by
Aguilera, Kristina Y.
,
Riahi, Rana
,
Saadat, Edris A.
,
Lay, Anna R.
,
Le, Thuc
,
Cabebe, Anthony
,
Donahue, Timothy R.
,
Radu, Caius
,
Dawson, David W.
Published in
Cancer research (Chicago, Ill.)
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Cancer Research
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Molecular Cancer Therapeutics
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Acyltransferases - Antagonists & Inhibitors
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Acyltransferases - Genetics
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Acyltransferases - Metabolism
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Carcinoma, Pancreatic Ductal - Drug Therapy
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Carcinoma, Pancreatic Ductal - Genetics
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Carcinoma, Pancreatic Ductal - Metabolism
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Cell Line, Tumor
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Cell Proliferation
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Homeostasis
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Humans
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Ligands
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Membrane Proteins - Antagonists & Inhibitors
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Membrane Proteins - Genetics
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Membrane Proteins - Metabolism
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Mitochondria - Metabolism
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Pancreatic Neoplasms
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Pancreatic Neoplasms - Drug Therapy
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