Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes by White, Jacqueline K., Gerdin, Anna-Karin, Karp, Natasha A., Ryder, Ed, Bussell, James N., Salisbury, Jennifer, Clare, Simon, Ingham, Neil J., Podrini, Christine, Houghton, Richard, Estabel, Jeanne, Bottomley, Joanna R., Melvin, David G., Sunter, David, Barnes, Caroline, Cambridge, Emma, Carragher, Damian, Chana, Prabhjoat, Clarke, Kay, Igosheva, Natalia, Ismail, Ozama, Jackson, Hannah, Kane, Leanne, Lacey, Rosalind, Lucas, Mark, McGill, Katherine, McIntyre, Rebecca E., Messager, Sophie, Mottram, Lynda, Mulderrig, Lee, Pearson, Selina, Roberson, Laura-Anne, Salsbury, Grace, Sanger, Daniel, Shannon, Carl, Thompson, Paul C., Tuck, Elizabeth, Bushell, Wendy, Cook, Ross, Dalvi, Priya, Gleeson, Diane, Habib, Bishoy, Hardy, Matt, Miklejewska, Evelina, Price, Stacey, Sethi, Debarati, von Schiller, Dominique, Vyas, Sapna, West, Anthony P., Evans, Arthur, Holroyd, Simon, Iyer, Vivek, Lewis, Morag, Oakley, Darren, Richardson, David, Smedley, Damian, Agu, Chukwuma, Bryant, Jackie, Delaney, Liz, Gueorguieva, Nadia I., Tharagonnet, Helen, Townsend, Anne J., Biggs, Daniel, Collinson, Adam, Dumeau, Charles-Etienne, Grau, Evelyn, Harrison, Sarah, Ingle, Catherine E., Kundi, Helen, Madich, Alla, Mayhew, Danielle, Metcalf, Tom, Pass, Johanna, Reynolds, Helen, Sinclair, Caroline, Wardle-Jones, Hannah, Woods, Michael, Alexander, Liam, Brown, Terry, Flack, Francesca, Griggs, Nicola, McDermott, Jordan, Rogerson, Claire, White, Gemma, Zielezinski, Pawel, DiTommaso, Tia, Edwards, Andrew, Mahajan, Mary Ann, Yalcin, Binnaz, Tannahill, David, Logan, Darren W., MacArthur, Daniel G., Flint, Jonathan, Mahajan, Vinit B., Smyth, Ian, Watt, Fiona M., Skarnes, William C., Dougan, Gordon, Adams, David J., Bradley, Allan

Get full text

The role of sphingosine-1-phosphate transporter Spns2 in immune system function by Nijnik, Anastasia, Clare, Simon, Hale, Christine, Chen, Jing, Raisen, Claire, Mottram, Lynda, Lucas, Mark, Estabel, Jeanne, Ryder, Edward, Adissu, Hibret, Adams, Niels C, Ramirez-Solis, Ramiro, White, Jacqueline K, Steel, Karen P, Dougan, Gordon, Hancock, Robert E W

Get full text

Targeting of Slc25a21 is associated with orofacial defects and otitis media due to disrupted expression of a neighbouring gene by Maguire, Simon, Estabel, Jeanne, Ingham, Neil, Pearson, Selina, Ryder, Edward, Carragher, Damian M, Walker, Nicolas, Bussell, James, Chan, Wai-In, Keane, Thomas M, Adams, David J, Scudamore, Cheryl L, Lelliott, Christopher J, Ramírez-Solis, Ramiro, Karp, Natasha A, Steel, Karen P, White, Jacqueline K, Gerdin, Anna-Karin

Get full text

First-in-human in-vivo depiction of paraganglioma metabolism by hyperpolarised 13 C-magnetic resonance by Chowdhury, Rafat, Moorthy, Myuri, Smith, Lorna, Mueller, Christoph A, Gong, Fiona, Rogers, Harriet J, Papoutsaki, Marianthi-Vasiliki, Syer, Tom, Brembilla, Giorgio, Singh, Saurabh, Retter, Adam, Parry, Thomas, Clemente, Joey, Caselton, Lucy, Jeraj, Hassan, Bullock, Max, Mathew, Manju, Chung, Teng Teng, Akker, Scott, Chapple, Paul, Salsbury, Grace A, Bainbridge, Alan, Atkinson, David, Gadian, David G, Srirangalingam, Umasuthan, Punwani, Shonit

Get full text

First-in-human in-vivo depiction of paraganglioma metabolism by hyperpolarised 13C-magnetic resonance by Chowdhury, Rafat, Moorthy, Myuri, Smith, Lorna, Mueller, Christoph A, Gong, Fiona, Rogers, Harriet J, Papoutsaki, Marianthi-Vasiliki, Syer, Tom, Brembilla, Giorgio, Singh, Saurabh, Retter, Adam, Parry, Thomas, Clemente, Joey, Caselton, Lucy, Jeraj, Hassan, Bullock, Max, Mathew, Manju, Chung, Teng Teng, Akker, Scott, Chapple, Paul, Salsbury, Grace A, Bainbridge, Alan, Atkinson, David, Gadian, David G, Srirangalingam, Umasuthan, Punwani, Shonit

Get full text

CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs by Sladen, Paul E., Perdigão, Pedro R.L., Salsbury, Grace, Novoselova, Tatiana, van der Spuy, Jacqueline, Chapple, J. Paul, Yu-Wai-Man, Patrick, Cheetham, Michael E.

Get full text

Altered Cellular Metabolism Is a Consequence of Loss of the Ataxia-Linked Protein Sacsin by Perna, Laura, Salsbury, Grace, Dushti, Mohammed, Smith, Christopher J, Morales, Valle, Bianchi, Katiuscia, Czibik, Gabor, Chapple, J Paul

Get full text

Modelling autosomal dominant optic atrophy associated with OPA1 variants in iPSC-derived retinal ganglion cells by Sladen, Paul E, Jovanovic, Katarina, Guarascio, Rosellina, Ottaviani, Daniele, Salsbury, Grace, Novoselova, Tatiana, Chapple, J Paul, Yu-Wai-Man, Patrick, Cheetham, Michael E

Get full text

SAT266 Transcriptional Changes Associated With Loss Of Function Of Fumarate Hydratase In A Cellular Model Of Pheochromocytoma by Hall, Charlotte Louise, Read, Jordan Elise, Salsbury, Grace, Lim, Eugénie, Akker, Scott, Chapple, Paul

Get full text

Subcellular Localization And Formation Of Huntingtin Aggregates Correlates With Symptom Onset And Progression In A Huntington’S Disease Model by Landles, Christian, Milton, Rebecca E, Ali, Nadira, Flomen, Rachel, Flower, Michael, Schindler, Franziska, Gomez-Paredes, Casandra, Bondulich, Marie K, Osborne, Georgina F, Goodwin, Daniel, Salsbury, Grace, Benn, Caroline L, Sathasivam, Kirupa, Smith, Edward J, Tabrizi, Sarah J, Wanker, Erich E, Bates, Gillian P

Get full text

Disruption of the potassium channel regulatory subunit KCNE2 causes iron-deficient anemia by Salsbury, Grace, Cambridge, Emma L, McIntyre, Zoe, Arends, Mark J, Karp, Natasha A, Isherwood, Christopher, Shannon, Carl, Hooks, Yvette, Ramirez-Solis, Ramiro, Adams, David J, White, Jacqueline K, Speak, Anneliese O

Get full text

Corrigendum to “Disruption of the potassium channel regulatory subunit KCNE2 causes iron-deficient anemia” [Experimental Hematology, Vol. 42, Issue 12, p1053–1058.e1] by Salsbury, Grace, Cambridge, Emma L, McIntyre, Zoe, Arends, Mark J, Karp, Natasha A, Isherwood, Christopher, Shannon, Carl, Hooks, Yvette, Ramirez-Solis, Ramiro, Adams, David J, White, Jacqueline K, Speak, Anneliese O

Get full text