CTLA-4: a moving target in immunotherapy by Rowshanravan, Behzad, Halliday, Neil, Sansom, David M.

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Moving CTLA-4 from the trash to recycling by Sansom, David M

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Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4 by Qureshi, Omar S., Zheng, Yong, Nakamura, Kyoko, Attridge, Kesley, Manzotti, Claire, Schmidt, Emily M., Baker, Jennifer, Jeffery, Louisa E., Kaur, Satdip, Briggs, Zoe, Hou, Tie Z., Futter, Clare E., Anderson, Graham, Walker, Lucy S.K., Sansom, David M.

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CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement by Wang, Chun Jing, Heuts, Frank, Ovcinnikovs, Vitalijs, Wardzinski, Lukasz, Bowers, Chantelle, Schmidt, Emily M., Kogimtzis, Alexandros, Kenefeck, Rupert, Sansom, David M., Walker, Lucy S. K.

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Thymus transplantation for complete DiGeorge syndrome: European experience by Davies, E. Graham, FRCPCH, Cheung, Melissa, BSc, Gilmour, Kimberly, PhD, Maimaris, Jesmeen, MRCPCH, Curry, Joe, FRCS, Furmanski, Anna, PhD, Sebire, Neil, FRCPATH, Halliday, Neil, MB, BSc, Mengrelis, Konstantinos, PhD, Adams, Stuart, PhD, Bernatoniene, Jolanta, MD, Bremner, Ronald, FRCPCH, Browning, Michael, FRCPATH, Devlin, Blythe, PhD, Erichsen, Hans Christian, MD, Gaspar, H. Bobby, PhD, Hutchison, Lizzie, RCN, Ip, Winnie, PhD, Ifversen, Marianne, MD, Leahy, T. Ronan, PhD, McCarthy, Elizabeth, PhD, Moshous, Despina, PhD, Neuling, Kim, FRCPCH, Pac, Malgorzata, MD, Papadopol, Alina, MD, Parsley, Kathryn L., PhD, Poliani, Luigi, PhD, Ricciardelli, Ida, PhD, Sansom, David M., PhD, Voor, Tiia, MD, Worth, Austen, PhD, Crompton, Tessa, PhD, Markert, M. Louise, PhD, Thrasher, Adrian J., PhD

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Characterization of CTLA4 Trafficking and Implications for Its Function by Khailaie, Sahamoddin, Rowshanravan, Behzad, Robert, Philippe A., Waters, Erin, Halliday, Neil, Badillo Herrera, Jesus David, Walker, Lucy S.K., Sansom, David M., Meyer-Hermann, Michael

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CD86 Is a Selective CD28 Ligand Supporting FoxP3+ Regulatory T Cell Homeostasis in the Presence of High Levels of CTLA-4 by Halliday, Neil, Williams, Cayman, Kennedy, Alan, Waters, Erin, Pesenacker, Anne M, Soskic, Blagoje, Hinze, Claudia, Hou, Tie Zheng, Rowshanravan, Behzad, Janman, Daniel, Walker, Lucy S K, Sansom, David M

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Impact of CTLA-4 checkpoint antibodies on ligand binding and Transendocytosis by Williams, Cayman, Kennedy, Alan, Robinson, Maximillian A, Lloyd, Christopher, Dovedi, Simon J, Sansom, David M

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CTLA-4-mediated transendocytosis of costimulatory molecules primarily targets migratory dendritic cells by Ovcinnikovs, Vitalijs, Ross, Ellen M, Petersone, Lina, Edner, Natalie M, Heuts, Frank, Ntavli, Elisavet, Kogimtzis, Alexandros, Kennedy, Alan, Wang, Chun Jing, Bennett, Clare L, Sansom, David M, Walker, Lucy S K

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CD80 on Human T Cells Is Associated With FoxP3 Expression and Supports Treg Homeostasis by Soskic, Blagoje, Jeffery, Louisa E, Kennedy, Alan, Gardner, David H, Hou, Tie Zheng, Halliday, Neil, Williams, Cayman, Janman, Daniel, Rowshanravan, Behzad, Hirschfield, Gideon M, Sansom, David M

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Vitamin D Antagonises the Suppressive Effect of Inflammatory Cytokines on CTLA-4 Expression and Regulatory Function by Jeffery, Louisa E, Qureshi, Omar S, Gardner, David, Hou, Tie Z, Briggs, Zoe, Soskic, Blagoje, Baker, Jennifer, Raza, Karim, Sansom, David M

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Rigid, bivalent CTLA-4 binding to CD80 is required to disrupt the cis CD80/PD-L1 interaction by Robinson, Maximillian A., Kennedy, Alan, Orozco, Carolina T., Chen, Hung-Chang, Waters, Erin, Giovacchini, Dalisay, Yeung, Kay, Filer, Lily, Hinze, Claudia, Lloyd, Christopher, Dovedi, Simon J., Sansom, David M.

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What's the difference between CD80 and CD86? by Sansom, David M., Manzotti, Claire N., Zheng, Yong

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CTLA4 gene polymorphism and autoimmunity by Gough, Stephen C. L., Walker, Lucy S. K., Sansom, David M.

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Confusing signals: Recent progress in CTLA-4 biology by Walker, Lucy S.K, Sansom, David M

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Comparison of the intracellular trafficking itinerary of ctla-4 orthologues by Kaur, Satdip, Qureshi, Omar S, Sansom, David M

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Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4–insufficient subjects by Schwab, Charlotte, Gabrysch, Annemarie, Olbrich, Peter, Patiño, Virginia, Warnatz, Klaus, Wolff, Daniel, Hoshino, Akihiro, Kobayashi, Masao, Imai, Kohsuke, Takagi, Masatoshi, Dybedal, Ingunn, Haddock, Jamanda A., Sansom, David M., Lucena, Jose M., Seidl, Maximilian, Schmitt-Graeff, Annette, Reiser, Veronika, Emmerich, Florian, Frede, Natalie, Bulashevska, Alla, Salzer, Ulrich, Schubert, Desirée, Hayakawa, Seiichi, Okada, Satoshi, Kanariou, Maria, Kucuk, Zeynep Yesim, Chapdelaine, Hugo, Petruzelkova, Lenka, Sumnik, Zdenek, Sediva, Anna, Slatter, Mary, Arkwright, Peter D., Cant, Andrew, Lorenz, Hanns-Martin, Giese, Thomas, Lougaris, Vassilios, Plebani, Alessandro, Price, Christina, Sullivan, Kathleen E., Moutschen, Michel, Litzman, Jiri, Freiberger, Tomas, van de Veerdonk, Frank L., Recher, Mike, Albert, Michael H., Hauck, Fabian, Seneviratne, Suranjith, Pachlopnik Schmid, Jana, Kolios, Antonios, Unglik, Gary, Klemann, Christian, Speckmann, Carsten, Ehl, Stephan, Leichtner, Alan, Blumberg, Richard, Franke, Andre, Snapper, Scott, Zeissig, Sebastian, Cunningham-Rundles, Charlotte, Giulino-Roth, Lisa, Elemento, Olivier, Dückers, Gregor, Niehues, Tim, Fronkova, Eva, Kanderová, Veronika, Platt, Craig D., Chou, Janet, Chatila, Talal A., Geha, Raif, McDermott, Elizabeth, Bunn, Su, Kurzai, Monika, Schulz, Ansgar, Alsina, Laia, Casals, Ferran, Deyà-Martinez, Angela, Hambleton, Sophie, Kanegane, Hirokazu, Taskén, Kjetil, Neth, Olaf, Grimbacher, Bodo

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The CTLA‐4 immune checkpoint protein regulates PD‐L1:PD‐1 interaction via transendocytosis of its ligand CD80 by Kennedy, Alan, Robinson, Maximillian A, Hinze, Claudia, Waters, Erin, Williams, Cayman, Halliday, Neil, Dovedi, Simon, Sansom, David M

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Availability of 25-Hydroxyvitamin D3 to APCs Controls the Balance between Regulatory and Inflammatory T Cell Responses by Jeffery, Louisa E., Wood, Alice M., Qureshi, Omar S., Hou, Tie Zheng, Gardner, David, Briggs, Zoe, Kaur, Satdip, Raza, Karim, Sansom, David M.

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1,25-Dihydroxyvitamin D3 and IL-2 Combine to Inhibit T Cell Production of Inflammatory Cytokines and Promote Development of Regulatory T Cells Expressing CTLA-4 and FoxP3 by Jeffery, Louisa E, Burke, Fiona, Mura, Manuela, Zheng, Yong, Qureshi, Omar S, Hewison, Martin, Walker, Lucy S. K, Lammas, David A, Raza, Karim, Sansom, David M

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