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Ig V region hypermutation in B cell hybrids mimics in vivo mutation and allows for isolation of clonal variants
by
Green, Nancy S.
,
Verdugoj, Gonzalo
,
Getman, Michael E.
,
Scharft, Matthew D.
Published in
Molecular immunology
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Molecular Immunology
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B-Lymphocytes - Chemistry
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B-Lymphocytes - Immunology
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Base Sequence
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Biochemistry & Molecular Biology
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Cell Separation
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Clone Cells - Chemistry
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Clone Cells - Immunology
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Codon, Terminator - Genetics
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Dna - Chemistry
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Hot Spot
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Humans
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Hybrid Cells - Chemistry
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Hybrid Cells - Immunology
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Hybridoma
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Igh Construct
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Immunoglobulin Heavy Chains - Genetics
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Immunoglobulin Variable Region - Genetics
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Immunology
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In Situ Hybridization, Fluorescence
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Life Sciences & Biomedicine
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